Abstract: A medical procedure system, including a medical instrument to be inserted into a body part, and including position-tracking transducers to provide position signals, a distal end, and at least one radiopaque marker, a position tracking sub-system to compute a position including at least one location and orientation of the distal end in a position-tracking sub-system coordinate frame responsively to the position signals, a fluoroscope to capture fluoroscopic images of an interior of the body part and the radiopaque marker(s), and a registration sub-system to render, to a display, the captured fluoroscopic images including at least one marker-image of the radiopaque marker(s), and at least one graphical representation indicative of the computed position of the distal end, receive user-alignment input aligning the graphical representation(s) with the marker-image(s), and register the position-tracking sub-system coordinate frame with a coordinate frame of the fluoroscope responsively to the received user-alignmen

Abstract: In one embodiment, a medical system includes a catheter configured to be inserted into a chamber of a heart of a living subject, and including catheter electrodes configured to contact tissue at respective locations within the chamber of the heart, a display, and a processing circuitry configured to receive respective signals from the catheter captured by respective ones of the electrodes, assess conformity of each of the respective signals to at least one signal characteristic, find a given one of the signals of a given one of the electrodes not conforming to the at least one signal characteristic for a given time period, and render to the display an indication that the given signal of the given electrode does not conform to the at least one signal characteristic for the given time period.

Abstract: In one embodiment, a medical system includes a catheter configured to be inserted into a chamber of a heart of a living subject, and including a distal end including catheter electrodes configured to contact tissue at respective locations within the chamber of the heart, at least one position sensor configured to provide at least one position signal indicative of a position of the distal end, a display, and processing circuitry configured to compute the position of the distal end of the catheter responsively to the at least one position signal, render to the display a 3D anatomical map of the chamber of the heart and a 3D representation of the distal end of the catheter, and render to the display over at least part of the map, at least one intracardiac electrogram trace representing electrical activity in the tissue that is sensed by at least one of the catheter electrodes.

Abstract: A catheter includes an insertion tube, a flexible substrate and one or more electrical devices. The insertion tube is configured for insertion into a patient body. The flexible substrate is configured to wrap around a distal end of the insertion tube and includes electrical interconnections. The electrical devices are coupled to the flexible substrate and are connected to the electrical interconnections.

Abstract: The subject of this disclosure is devices, systems, and uses thereof to treat a plurality of patients for paroxysmal atrial fibrillation. The solution can include delivering a multi-electrode radiofrequency balloon catheter and a multi-electrode diagnostic catheter to one or more targeted pulmonary veins; ablating tissue of the one or more targeted pulmonary veins using the multi-electrode radiofrequency balloon catheter; diagnosing the one or more targeted pulmonary veins using the multi-electrode diagnostic catheter; and achieving at least one of a predetermined clinical effectiveness and acute effectiveness of the method or use based on use of the multi-electrode radiofrequency balloon catheter and the multi-electrode diagnostic catheter in the isolation of the one or more targeted pulmonary veins.

Abstract: In one embodiment, a medical system includes a catheter configured to be inserted into a body part of a living subject, and including a deflectable element having a distal end, an expandable distal end assembly disposed at the distal end of the deflectable element, and comprising a plurality of electrodes, a distal portion, and a proximal portion, and configured to expand from a collapsed form to an expanded deployed form, and a stretchable irrigation tube disposed between the distal portion and the proximal portion, and comprising a plurality of irrigation holes, and configured to stretch longitudinally when the distal end assembly is collapsed from the expanded deployed form to the collapsed form.

Abstract: Apparatus, consisting of a probe configured to be inserted into contact with a myocardium, and an electrode attached to the probe. A temperature sensor, incorporated in the probe, is configured to output a temperature signal. A pump irrigates the myocardium, via the probe, with an irrigation fluid at a controllable rate, and a radiofrequency (RF) signal generator applies RF power via the electrode to the myocardium, so as to ablate the myocardium. The apparatus also has processing circuitry that measures a temperature of the probe, based on the temperature signal, while the RF power is applied and, when the measured temperature exceeds a preset target temperature, iteratively reduces the RF power applied by the signal generator and concurrently iteratively varies a rate of irrigation of the irrigation fluid provided by the pump, until the measured temperature is reduced to the preset target temperature.

Abstract: A system includes a catheter and a processor. The catheter includes an expandable distal-end assembly (EDEA) having: (i) a transmitter, which is coupled to the EDEA and is configured to transmit a first signal, and (ii) one or more receivers, which are coupled to an elastic component of the EDEA, and are configured to produce one or more respective second signals in response to receiving the first signal. The processor is configured to estimate, based on the one or more respective second signals, a force applied to the elastic component.

Abstract: A ventilator system for a patient includes: an intubation tube configured to flow oxygen-enriched humidified air (OHA) toward patient lungs and to evacuate exhaust air exhaled from the lungs, the intubation tube includes: a distal end, configured to be inserted into patient trachea, and a proximal end, configured to be connected to tubes for receiving the OHA and evacuating the exhaust air; a first microgravity sensor, coupled to the intubation tube at a first position, and configured to produce a first signal indicative of a first micro-acceleration of the intubation tube at the first position; a second microgravity sensor, coupled to the intubation tube at a second different position, and configured to produce a second signal indicative of a second micro-acceleration of the intubation tube at the second position; and a processor, configured to control the ventilation system to apply a ventilation scheme responsively to the first and second signals.

Abstract: In one embodiment a medical tracking system, including a catheter to be inserted into blood vessels of a body-part of a living subject, and including a flexible shaft having a deflectable distal end, and a location tracking transducer in the distal end configured to output a signal indicative of a location of the transducer, a tracking subsystem to track locations of the distal end over time responsively to the signal, a display, and processing circuitry to add the tracked locations of the distal end to a movement log, and render to the display an image of at least part of the body-part with a representation of a length of the shaft of the catheter in at least one blood vessel of the body-part, with respective positions along the length of the shaft being located in the image responsively to respective ones of the tracked locations from the movement log.

Abstract: Medical apparatus includes an insertion tube configured for insertion into a body cavity of a patient and an expandable assembly connected distally to the insertion tube and comprising electrodes, which are configured to apply electrical energy to tissue within the body cavity. A flexible porous sheath is fitted over the expandable assembly and configured to contact the tissue within the body cavity so that the electrical energy is applied from the electrodes through the sheath to the tissue.

Abstract: Catheterization is carried out by inserting a probe into a cavity in a body of a subject. The probe has a contact force, a transmitter, a receiver, and an ultrasound transducer in its distal segment. After navigating the probe into contact with a target in a wall of the cavity using the contact force sensor, a desired contact force is established and maintained between the probe and the target. Responsively to readings by the receiver of signals from the transmitter, the distal end of the probe is oriented orthogonally to the target.

Abstract: Methods and systems are provided for training machine learning (e.g., NN) or other artificial intelligence (AI) models to control a robot arm to manipulate a catheter to robotically perform an invasive clinical catheter-based procedure.

Abstract: An electroporation ablation system includes a probe to be inserted into a body part of a living subject, and including a distal end including at least one electrode, body-surface patches to be applied to a skin surface, an ablation power generator to apply at least one first electrical pulse train between the electrode(s) and first one(s) of the body-surface patches, and a processor to provide a measurement of movement of the living subject responsively to applying the first electrical pulse train(s) between the electrode(s) and the first one(s) of the body-surface patches, and select second one(s) of the body-surface patches responsively to the measurement of movement, and wherein the ablation power generator is configured to apply at least one second electrical pulse train between the electrode(s) and the second one(s) of the body-surface patches.

Abstract: A location pad includes multiple field-generators and a frame. The multiple field-generators are configured to generate respective magnetic fields in a region-of-interest of a patient organ, so as to measure a position of a medical instrument in the region-of-interest. The frame is transparent to an X-ray radiation, and is configured to fix the multiple field-generators at respective positions surrounding the region-of-interest.

Abstract: An apparatus includes an interface and a processor. The interface is configured to receive one or more magnetic-positioning signals from one or more position sensors coupled to one or more body-surface patches attached to a body of a patient, the magnetic-positioning signals indicative of respective positions of the position sensors. The processor is configured to (i) detect an inadvertent stimulation of a phrenic nerve of the patient, which occurs due to cardiac pacing applied by an intra-cardiac electrode in a heart of the patient, (ii) estimate, based on the magnetic-positioning signals, a motion of one or more of the body-surface patches occurring during the detected stimulation of the phrenic nerve, (iii) estimate, based on the estimated motion of the body-surface patches, a distance between the pacing electrode and the phrenic nerve, and (iv) send an output derived from the estimated distance to the output device.

Abstract: A location pad includes multiple field-generators, a frame and a mounting fixture. The multiple field-generators are configured to generate respective magnetic fields in a region-of-interest of a patient body, for measuring a position of a medical instrument in the region-of-interest. The frame is configured to fix the multiple field-generators at respective positions surrounding the region-of-interest. The mounting fixture is configured to position the frame above the patient body.

Abstract: A system includes a catheter and a processor. The catheter includes a distal-end assembly coupled to a distal end of a shaft for insertion into a cavity of an organ of a patient, the distal-end assembly including (i) one or more functional electrodes configured to be placed in contact with wall tissue of the cavity and (ii) a reference electrode configured to be placed in the cavity but not in contact with the wall tissue. The processor is configured to (i) estimate one or more impedances between one or more of the functional electrodes and the reference electrode, and (ii) based on the impedances, determine, for at least a functional electrode from among the one or more functional electrodes, whether the functional electrode is in physical contact with the wall tissue.

Abstract: A method includes, receiving a first electrocardiogram (ECG) signal, which is acquired in a heart of a patient and is distorted by interference. One or more external signals that sense the interference concurrently with acquisition of the first ECG signal are received from one or more sources external to the heart. A second ECG signal, in which the interference is suppressed relative to the first ECG signal, is produced by applying a trained Neural Network (NN) to the first ECG signal and to the one or more external signals.

Abstract: A phacoemulsification device includes a needle, one or more piezoelectric crystals, and one or more thermocouples. The needle is configured for insertion into a lens capsule of an eye. The one or more piezoelectric crystals are configured to vibrate the needle. The one or more thermocouples are thermally coupled directly to the respective piezoelectric crystals and are configured to measure respective temperatures of the one or more piezoelectric crystals as the crystals vibrate, and to output indications of the respectively measured temperatures.