Patents by Inventor Athanasios Polymeridis

Athanasios Polymeridis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10359486
    Abstract: During operation, a system may apply a polarizing field and an excitation sequence to a sample. Then, the system may measure a signal associated with the sample for a time duration that is less than a magnitude of a relaxation time associated with the sample. Next, the system may calculate the relaxation time based on a difference between the measured signal and a predicted signal of the sample, where the predicted signal is based on a forward model, the polarizing field and the excitation sequence. After modifying at least one of the polarizing field and the excitation sequence, the aforementioned operations may be repeated until a magnitude of the difference is less than a convergence criterion. Note that the calculations may be performed concurrently with the measurements and may not involve performing a Fourier transform on the measured signal.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: July 23, 2019
    Assignee: Q Bio, Inc.
    Inventors: Jeffrey Howard Kaditz, Athanasios Polymeridis, Jorge Fernandez Villena, Deepak Ramaswamy, Jacob White
  • Publication number: 20190154783
    Abstract: During operation, a system may apply an external magnetic field and an RF pulse sequence to a sample. Then, the system may measure at least a component of a magnetization associated with the sample, such as MR signals of one or more types of nuclei in the sample. Moreover, the system may calculate at least a predicted component of the magnetization for voxels associated with the sample based on the measured component of the magnetization, a forward model, the external magnetic field and the RF pulse sequence. Next, the system may solve an inverse problem by iteratively modifying the parameters associated with the voxels in the forward model until a difference between the predicted component of the magnetization and the measured component of the magnetization is less than a predefined value. Note that the calculations may be performed concurrently with the measurements and may not involve performing a Fourier transform.
    Type: Application
    Filed: January 7, 2019
    Publication date: May 23, 2019
    Applicant: Q Bio, Inc
    Inventors: Jeffrey H. Kaditz, Athanasios Polymeridis, Jorge Villena
  • Patent number: 10222441
    Abstract: During operation, a system may apply an external magnetic field and an RF pulse sequence to a sample. Then, the system may measure at least a component of a magnetization associated with the sample, such as MR signals of one or more types of nuclei in the sample. Moreover, the system may calculate at least a predicted component of the magnetization for voxels associated with the sample based on the measured component of the magnetization, a forward model, the external magnetic field and the RF pulse sequence. Next, the system may solve an inverse problem by iteratively modifying the parameters associated with the voxels in the forward model until a difference between the predicted component of the magnetization and the measured component of the magnetization is less than a predefined value. Note that the calculations may be performed concurrently with the measurements and may not involve performing a Fourier transform.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: March 5, 2019
    Assignee: Q Bio, Inc.
    Inventors: Jeffrey Howard Kaditz, Athanasios Polymeridis, Jorge Fernandez Villena
  • Publication number: 20170303813
    Abstract: A plurality of stimulations is transmitted to tissue or other material using one or more transmitters. The plurality of signals associated with the excited tissue and the transmitted stimulations are measured. The measured signals are processed to generate field-related quantities, such as B1+ and/or MR signal maps. Field-related quantities are generated also from simulation, by calculating the one or more incident fields from a simulator model of the one or more transmitters and assuming a given distribution of electrical properties in the tissue or other material. Field-related quantities generated from simulation and experimental procedures are compared to each other. The assumed electrical properties distribution is updated and the procedure is repeated iteratively until the difference between simulated and experimental field-related quantities is smaller than a threshold.
    Type: Application
    Filed: April 21, 2017
    Publication date: October 26, 2017
    Inventors: Riccardo LATTANZI, Daniel K. SODICKSON, José E. CRUZ SERRALLES, Athanasios POLYMERIDIS, Luca DANIEL, Jacob K. WHITE
  • Publication number: 20170285122
    Abstract: During operation, a system may apply a polarizing field and an excitation sequence to a sample. Then, the system may measure a signal associated with the sample for a time duration that is less than a magnitude of a relaxation time associated with the sample. Next, the system may calculate the relaxation time based on a difference between the measured signal and a predicted signal of the sample, where the predicted signal is based on a forward model, the polarizing field and the excitation sequence. After modifying at least one of the polarizing field and the excitation sequence, the aforementioned operations may be repeated until a magnitude of the difference is less than a convergence criterion. Note that the calculations may be performed concurrently with the measurements and may not involve performing a Fourier transform on the measured signal.
    Type: Application
    Filed: November 28, 2016
    Publication date: October 5, 2017
    Applicant: Q Bio, Inc
    Inventors: Jeffrey Howard Kaditz, Athanasios Polymeridis, Jorge Fernandez Villena, Deepak Ramaswamy, Jacob White
  • Publication number: 20170285123
    Abstract: During operation, a system may apply an external magnetic field and an RF pulse sequence to a sample. Then, the system may measure at least a component of a magnetization associated with the sample, such as MR signals of one or more types of nuclei in the sample. Moreover, the system may calculate at least a predicted component of the magnetization for voxels associated with the sample based on the measured component of the magnetization, a forward model, the external magnetic field and the RF pulse sequence. Next, the system may solve an inverse problem by iteratively modifying the parameters associated with the voxels in the forward model until a difference between the predicted component of the magnetization and the measured component of the magnetization is less than a predefined value. Note that the calculations may be performed concurrently with the measurements and may not involve performing a Fourier transform.
    Type: Application
    Filed: November 28, 2016
    Publication date: October 5, 2017
    Applicant: Q Bio, Inc
    Inventors: Jeffrey Howard Kaditz, Athanasios Polymeridis, Jorge Fernandez Villena, Deepak Ramaswamy, Jacob White