Patents by Inventor Atsunori Hiratsuka
Atsunori Hiratsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11906461Abstract: Provided is a means for promoting electron transfer between nanocarbon and other substances. An electron transfer accelerator for nanocarbon comprising a compound having an aromatic ring Skelton.Type: GrantFiled: March 29, 2019Date of Patent: February 20, 2024Assignees: TOYOBO CO., LTD., NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Katsumi Tsuji, Keizo Yoneda, Atsushi Sogabe, Atsunori Hiratsuka, Hitoshi Muguruma, Hisanori Iwasa, Takeshi Tanaka, Kouhei Orihara
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Patent number: 11136612Abstract: A reagent used for a glucose sensor for electrochemical, quantitative determination of glucose, includes a flavin adenine dinucleotide glucose dehydrogenase, single-walled carbon nanotubes, and a dispersant.Type: GrantFiled: August 7, 2017Date of Patent: October 5, 2021Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Hitoshi Muguruma, Atsunori Hiratsuka, Hisanori Iwasa, Jun Takagi, Hiroyasu Kadoya
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Publication number: 20210293742Abstract: Provided is a means for promoting electron transfer between nanocarbon and other substances. An electron transfer accelerator for nanocarbon comprising a compound having an aromatic ring skeleton.Type: ApplicationFiled: March 29, 2019Publication date: September 23, 2021Applicants: TOYOBO CO., LTD., NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Katsumi TSUJI, Keizo YONEDA, Atsushi SOGABE, Atsunori HIRATSUKA, Hitoshi MUGURUMA, Hisanori IWASA, Takeshi TANAKA, Kouhei ORIHARA
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Publication number: 20190194714Abstract: A reagent used for a glucose sensor for electrochemical, quantitative determination of glucose, includes a flavin adenine dinucleotide glucose dehydrogenase, single-walled carbon nanotubes, and a dispersant.Type: ApplicationFiled: August 7, 2017Publication date: June 27, 2019Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Hitoshi MUGURUMA, Atsunori HIRATSUKA, Hisanori IWASA, Jun TAKAGI, Hiroyasu KADOYA
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Publication number: 20150267178Abstract: The present invention provides a protein derived from a thermophilic filamentous fungus having flavin adenine dinucleotide-dependent glucose dehydrogenase activity. The present invention provides an enzyme for glucose measurement that has better thermal stability than that of conventional enzymes while being unaffected by dissolved oxygen, not requiring the addition of a coenzyme, and maintaining the excellent properties of FADGDH in terms of having excellent substrate specificity (particularly low reactivity with maltose).Type: ApplicationFiled: September 9, 2013Publication date: September 24, 2015Inventors: Kazumichi Ozawa, Noriko Sasaki, Atsunori Hiratsuka, Kenji Yokoyama, Nao Kinoshita, Hideaki Ooe, Jun Takagi, Koji Tanaka, Katsushige Kotani
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Publication number: 20150027886Abstract: Provided is a technique capable of suppressing reduction of a mediator in a stored state. A reagent layer (an enzyme layer 106b, a mediator layer 106c) stacked separately on a hydrophilic layer 106a containing a hydrophilic polymer having a double bond of oxygen atoms contains an enzyme, a mediator, and a hydrophilic polymer having no double bond of oxygen atoms. Accordingly, since the mediator is surrounded by the hydrophilic polymer having no double bond of oxygen atoms, the mediator contained in mediator layer 106c can be prevented from coming into contact with CMC as the hydrophilic polymer in hydrophilic layer 106a, and reduction of the mediator by the hydrophilic polymer having a double bond of oxygen atoms in hydrophilic layer 106a can be suppressed, in the stored state.Type: ApplicationFiled: September 11, 2014Publication date: January 29, 2015Inventors: Jun Takagi, Hideaki Ooe, Kenji Yokoyama, Atsunori Hiratsuka, Noriko Sasaki
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Publication number: 20140373347Abstract: Provided is a technique capable of easily manufacturing a biosensor in which each of an enzyme layer and a mediator layer contains a hydrophilic polymer having no double bond of oxygen atoms and thereby which can be stored for a long period. Since an enzyme layer and a mediator layer are formed together as a reaction layer, there is no need to individually form enzyme layer and mediator layer on a cover layer and an electrode layer, respectively, as in a conventional biosensor, and reaction layer can be easily formed. Since each of enzyme layer and mediator layer contains the hydrophilic polymer having no double bond of oxygen atoms, a reaction between an enzyme and a mediator can be suppressed, and reduction of the mediator in mediator layer can be suppressed, in a stored state. Therefore, a biosensor which can be stored for a long period can be easily manufactured.Type: ApplicationFiled: September 11, 2014Publication date: December 25, 2014Inventors: Jun Takagi, Hideaki Ooe, Kenji Yokoyama, Atsunori Hiratsuka, Noriko Sasaki
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Publication number: 20140246336Abstract: A technique allowing improved determination accuracy in quantifying a substance to be determined by lessening influence by a current component different from an oxidation current is provided. The oxidation current results from oxidation of a reducing substance generated through reaction between an enzyme and the substance to be determined. Current components are contained in a response current resulting from application of a determination potential, referenced to a counter electrode, to a working electrode. Since a conditioning potential higher than a determination potential is applied as a pulse to the working electrode, influence by a current component different from an oxidation current can be lessened. Thus, the response current can be measured in a stable manner and determination accuracy in quantification of a substance to be determined which is contained in a specimen can be improved.Type: ApplicationFiled: May 15, 2014Publication date: September 4, 2014Applicant: Murata Manufacturing Co., Ltd.Inventors: Hideaki OOE, Jun TAKAGI, Kenji YOKOYAMA, Atsunori HIRATSUKA, Nobuyuki YOSHIDA, Noriko SASAKI
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Publication number: 20140246335Abstract: A technique and a sensor chip allowing determination of a hematocrit value of a blood sample in a short period of time with low cost are provided. A response current obtained by sweep of a voltage applied across a working electrode for determination and a counter electrode for determination included in a sensor chip is measured and a hematocrit value is derived based on followability of the response current to temporal change in swept applied voltage. Therefore, it is not necessary to stand by until oxidation reduction reaction of an oxidation reducing substance is stabilized for determining a hematocrit value as in a conventional method of determining a hematocrit value, and thus a hematocrit value of a blood sample can be determined in a short period of time. Since no oxidation reducing substance is necessary for determining a hematocrit value, a hematocrit value can be determined with low cost.Type: ApplicationFiled: May 15, 2014Publication date: September 4, 2014Applicant: Murata Manufacturing Co., Ltd.Inventors: Hideaki OOE, Jun TAKAGI, Kenji YOKOYAMA, Atsunori HIRATSUKA, Nobuyuki YOSHIDA, Noriko SASAKI
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Patent number: 8702950Abstract: A device for electrophoresis applies a voltage to a medium in contact with a plurality of electric conductors so that a potential of adjacent conductors is within a certain range. This allows preventing decline in electrophoresis speed. A device for electrophoresis and transfer includes an electrode having a plurality of electrode regions being insulated one another and arranged in a specific direction. This allows providing a practical and easy-to-use device for electrophoresis and transfer. A device for transfer alters an applied voltage or applied voltage duration to a certain position to another position. This allows improving transfer efficiency.Type: GrantFiled: September 10, 2012Date of Patent: April 22, 2014Assignees: Sharp Kabushiki Kaisha, Toppan Printing Co., Ltd.Inventors: Yuji Maruo, Yutaka Unuma, Atsunori Hiratsuka, Hideki Kinoshita, Kenji Yokoyama, Koji Sakairi, Satonari Akutsu
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Patent number: 8500981Abstract: An electrophoresis apparatus includes a sample separating section for containing a sample separating medium for separating a sample in a horizontal direction, the sample separating section containing the sample separating medium in such a manner that the sample separating medium has an exposed portion at least one end of a surface of the sample separating medium, the surface being in parallel with the horizontal direction; and medium connecting means for connecting a sample containing medium to the sample separating medium at a connecting region, the sample containing medium containing a sample, and the connecting region satisfying a particular equation. By this, an electrophoresis technique with better accuracy than conventional arts can be provided.Type: GrantFiled: July 15, 2009Date of Patent: August 6, 2013Assignees: Toppan Printing Co., Ltd., Sharp Kabushiki KaishaInventors: Koji Sakairi, Satonari Akutsu, Yuji Maruo, Takateru Matsunaga, Yutaka Unuma, Atsunori Hiratsuka, Hideki Kinoshita, Nao Sakaguchi, Kenji Yokoyama
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Patent number: 8449748Abstract: A sample separation/adsorption appliance (100) according to one embodiment of the present invention includes: a first buffer solution tank (103) equipped with a first electrode (101) and used for holding a first buffer solution; a second buffer solution tank (104) equipped with a second electrode (102) and used for holding a second buffer solution; a sample separation section (110) that holds a sample separation medium (131) for separating a sample; and a conductive section (120) that holds a conductive medium (133), wherein: the sample separation medium (131) and the conductive medium (133) are in contact with the sample adsorption member (132), respectively, on the opposite sides thereof; an end of the sample separation medium (131) opposite to an end being in contact with the sample adsorption member (132) is connected to an inside of the first buffer solution tank (103); and an end of the conductive medium (133) opposite to an end being in contact with the sample adsorption member (132) is connected to anType: GrantFiled: June 1, 2009Date of Patent: May 28, 2013Assignees: Sharp Kabushiki Kaisha, National Institute of Advanced Industrial Science and TechnologyInventors: Uichi Midorikawa, Takateru Matsunaga, Yuji Maruo, Yutaka Unuma, Atsunori Hiratsuka, Hideki Kinoshita, Kenji Yokoyama
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Patent number: 8419916Abstract: A biological molecule separation apparatus for separating a biological molecule of one embodiment of the present invention has a buffer solution chamber receiving a buffer solution, a separation electrode arranged in the buffer solution chamber, a biological molecule separation medium for separating a biological molecule, a biological molecule adsorption film for adsorbing a biological molecule, a pair of transfer electrodes having a plurality of line shaped conductors extending in a direction perpendicular to a first direction, the conductors being arranged in the direction perpendicular to the first direction, and a separation part which holds the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode, wherein the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode are stacked in this order.Type: GrantFiled: March 28, 2011Date of Patent: April 16, 2013Assignee: Toppan Printing Co., Ltd.Inventors: Koji Sakairi, Satonari Akutsu, Atsunori Hiratsuka, Kenji Yokoyama, Yuji Maruo, Hiroshi Ohki
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Publication number: 20130015069Abstract: A device for electrophoresis applies a voltage to a medium in contact with a plurality of electric conductors so that a potential of adjacent conductors is within a certain range. This allows preventing decline in electrophoresis speed. A device for electrophoresis and transfer includes an electrode having a plurality of electrode regions being insulated one another and arranged in a specific direction. This allows providing a practical and easy-to-use device for electrophoresis and transfer. A device for transfer alters an applied voltage or applied voltage duration to a certain position to another position. This allows improving transfer efficiency.Type: ApplicationFiled: September 10, 2012Publication date: January 17, 2013Applicant: Sharp Kabushiki Kaisha and Toppan Printing Co., Ltd.Inventors: Yuji MARUO, Yutaka Unuma, Atsunori Hiratsuka, Hideki Kinoshita, Kenji Yokoyama, Koji Sakairi, Satonari Akutsu
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Publication number: 20120273360Abstract: An instrument for electrophoresis includes a sample-separating portion in which a slab sample-separating medium that separates a sample is provided. The instrument for electrophoresis includes a sample-transporting portion that transports a sample-containing medium containing the sample to the sample-separating portion. The instrument for electrophoresis includes a positioning portion that is provided to the sample-separating portion and/or the sample-transporting portion and used for connecting the sample-transporting portion to a predetermined position of the sample-separating portion.Type: ApplicationFiled: December 21, 2010Publication date: November 1, 2012Inventors: Hideki Kinoshita, Yuji Maruo, Yutaka Unuma, Atsunori Hiratsuka, Koji Sakairi, Satonari Akutsu
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Patent number: 8221604Abstract: Transfer of fluid substances, and/or substances comprised in fluid substances, is controlled by introducing a separation medium, which prevents transfer of the fluid substances, and/or the substances comprised in the fluid substances, to an intermediate cavity connecting a first cavity and a second cavity; and introducing a connection medium to replace the separation medium and thereby start substance transfer to the second cavity. Substance transfer may be readily controlled without relying on mechanical means. Based on the present invention, two-dimensional electrophoretic analysis can be readily implemented on a chip.Type: GrantFiled: October 28, 2003Date of Patent: July 17, 2012Assignee: Katayanagi InstituteInventors: Kazuyoshi Yano, Isao Karube, Atsunori Hiratsuka, Shuo-Wen Tsai
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Publication number: 20110233062Abstract: A biological molecule separation apparatus for separating a biological molecule of one embodiment of the present invention has a buffer solution chamber receiving a buffer solution, a separation electrode arranged in the buffer solution chamber, a biological molecule separation medium for separating a biological molecule, a biological molecule adsorption film for adsorbing a biological molecule, a pair of transfer electrodes having a plurality of line shaped conductors extending in a direction perpendicular to a first direction, the conductors being arranged in the direction perpendicular to the first direction, and a separation part which holds the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode, wherein the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode are stacked in this order.Type: ApplicationFiled: March 28, 2011Publication date: September 29, 2011Applicant: Toppan Printing Co., Ltd.Inventors: Koji Sakairi, Satonari Akutsu, Atsunori Hiratsuka, Kenji Yokoyama, Yuji Maruo, Hiroshi Ohki
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Patent number: 7964077Abstract: The present invention is to provide a sample separation instrument used in a sample separation apparatus which includes: holding means for holding a first medium supporter which supports a first medium; and driving means for moving fixing means or the holding means in a direction parallel or perpendicular to a plane whose sides extend in the first direction and in the second directions. The sample separation instrument includes an insulator for storing a second medium which allows a sample separated in the first medium in the first direction to be further separated in the second direction different from the first direction, wherein: the insulator includes a first opening and a second opening each of which defines the second direction in which the second medium is electrified, and the second opening has a shape which allows the first medium containing the separated sample to be attached to the second medium along the first direction.Type: GrantFiled: August 28, 2006Date of Patent: June 21, 2011Assignees: Sharp Kabushiki Kaisha, Toppan Printing Co., LtdInventors: Yuji Maruo, Katsuyoshi Takahashi, Yutaka Unuma, Keisuke Usui, Hideki Kinoshita, Kisho Shiseki, Yoshio Suzuki, Atsunori Hiratsuka, Hiroyuki Fukui, Kenji Yokoyama, Ichiji Namatame, Kouhei Yodoya, Yasuhiro Ogawa, Koji Sakairi, Chie Hayashida, Satonari Akutsu, Kazuyoshi Yano, Isao Karube
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Publication number: 20110114485Abstract: An electrophoresis apparatus includes a sample separating section for containing a sample separating medium for separating a sample in a horizontal direction, the sample separating section containing the sample separating medium in such a manner that the sample separating medium has an exposed portion at least one end of a surface of the sample separating medium, the surface being in parallel with the horizontal direction; and medium connecting means for connecting a sample containing medium to the sample separating medium at a connecting region, the sample containing medium containing a sample, and the connecting region satisfying a particular equation. By this, an electrophoresis technique with better accuracy than conventional arts can be provided.Type: ApplicationFiled: July 15, 2009Publication date: May 19, 2011Inventors: Koji Sakairi, Satonari Akutsu, Yuji Maruo, Takateru Matsunaga, Yutaka Unuma, Atsunori Hiratsuka, Hideki Kinoshita, Nao Sakaguchi, Kenji Yokoyama
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Publication number: 20110094887Abstract: A sample separation/adsorption appliance (100) according to one embodiment of the present invention includes: a first buffer solution tank (103) equipped with a first electrode (101) and used for holding a first buffer solution; a second buffer solution tank (104) equipped with a second electrode (102) and used for holding a second buffer solution; a sample separation section (110) that holds a sample separation medium (131) for separating a sample; and a conductive section (120) that holds a conductive medium (133), wherein: the sample separation medium (131) and the conductive medium (133) are in contact with the sample adsorption member (132), respectively, on the opposite sides thereof; an end of the sample separation medium (131) opposite to an end being in contact with the sample adsorption member (132) is connected to an inside of the first buffer solution tank (103); and an end of the conductive medium (133) opposite to an end being in contact with the sample adsorption member (132) is connected to anType: ApplicationFiled: June 1, 2009Publication date: April 28, 2011Inventors: Uichi Midorikawa, Takateru Matsunaga, Yuji Maruo, Yutaka Unuma, Atsunori Hiratsuka, Hideki Kinoshita, Kenji Yokoyama