Abstract: The object of the present invention is to inject smoothly a precursor to be a support and make an excellent support in which a boundary between a separation gel and a concentration gel after the injection is not ill-defined in the cassette which is made by combining two plates made of a synthetic resin, and in order to achieve the object, the present invention provides an electrophoresis cassette made by combining plates made of a synthetic resin which has a cavity for forming a support, wherein the surface of the plate which contacts with the support is covered with a SiOx film, and the SiOx film has a contact angle to water of 30° or less, and preferably 10° or less.

Abstract: With the use of a chip (4) for electrophoresis and transfer including a transfer membrane (1) and an electrophoretic gel that is integrated with the transfer membrane (1), separation of a sample by electrophoresis and transfer of the sample separated to the transfer membrane (1) are carried out consecutively. This allows molecules separated on the gel by electrophoresis to be accurately transferred to the transfer membrane.

Abstract: A device for electrophoresis applies a voltage to a medium in contact with a plurality of electric conductors so that a potential of adjacent conductors is within a certain range. This allows preventing decline in electrophoresis speed. A device for electrophoresis and transfer includes an electrode having a plurality of electrode regions being insulated one another and arranged in a specific direction. This allows providing a practical and easy-to-use device for electrophoresis and transfer. A device for transfer alters an applied voltage or applied voltage duration to a certain position to another position. This allows improving transfer efficiency.

Abstract: The present invention is to provide a sample separation instrument used in a sample separation apparatus which includes: holding means for holding a first medium supporter which supports a first medium; and driving means for moving fixing means or the holding means in a direction parallel or perpendicular to a plane whose sides extend in the first direction and in the second directions. The sample separation instrument includes an insulator for storing a second medium which allows a sample separated in the first medium in the first direction to be further separated in the second direction different from the first direction, wherein: the insulator includes a first opening and a second opening each of which defines the second direction in which the second medium is electrified, and the second opening has a shape which allows the first medium containing the separated sample to be attached to the second medium along the first direction.

Abstract: A novel biosensor was accomplished using a plasma-polymerized membrane. The biosensor of the present invention is a high-performance biosensor produced by a simpler method and applicable to a wide range of fields.

Abstract: Transfer of fluid substances, and/or substances comprised in fluid substances, is controlled by introducing a separation medium, which prevents transfer of the fluid substances, and/or the substances comprised in the fluid substances, to an intermediate cavity connecting a first cavity and a second cavity; and introducing a connection medium to replace the separation medium and thereby start substance transfer to the second cavity. Substance transfer may be readily controlled without relying on mechanical means. Based on the present invention, two-dimensional electrophoretic analysis can be readily implemented on a chip.

Abstract: An objective of the present invention is to provide electrophoretic separation methods and devices that enable the various features of a substrate surface that comes in contact with an electrophoresis medium to be controlled. The present invention provides methods for electrophoresing substances, which comprises the steps of: (a) adding a substance to be analyzed to an electrophoresis medium retained in a substrate, whose surface that has come in contact with the electrophoresis medium has been coated with a polymer membrane; and (b) adding electrophoretic pressure to the electrophoresis medium. For example, the use of a plasma-polymerized membrane allows the formation of a membrane with homogeneous quality and thickness on the surface of an arbitrary shape. In addition, desired characteristics can be conferred on the surface through selection of monomeric substances. Protein adsorption onto micro-chips can be effectively prevented as well.

Abstract: The present invention relates to a filter for filtering a blood sample containing a blood cell component, which comprises a main body which defines a channel for causing the blood sample to flow, an opening for introducing the blood sample, the opening being located at one end of the channel, and an opening for discharging the blood sample filtered through the channel, the opening being located at the other end of the channel. A plurality of structures are disposed in the channel to prevent the blood cell component from passing through the channel. The structures are disposed at intervals such that a slit through which the blood cell component cannot pass is formed between each structure and an adjacent inner wall of the channel and between adjacent structures. The plurality of structures and the inner wall of the channel define at least one cavity functioning as a blood cell reservoir for accommodating the blood cell component in the channel.

Abstract: An invasive apparatus for obtaining an in vivo fluid is provided wherein the invasive apparatus includes a different stimulus applying portion for applying a stimulus different from a stimulus applied by an invasive portion to an organism in a leading end area other than a hole through which the invasive portion exits. The invasive portion is a hollow tube, knife, needle or laser beam, and the different stimulus is a mechanical stimulus. A recessed portion and/or raised portion is formed in the area other than the hole, and the different stimulus applying portion is the recessed portion and/or raised portion. The different stimulus is given by the recessed portion and/or raised portion.