Patents by Inventor Atsushi Izawa

Atsushi Izawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220007496
    Abstract: An optical module includes a box-shaped housing with an optical element mounted therein. Further, a wiring substrate is bonded to a part of a surface of a housing part of the housing, and an electric wiring, which is formed in the wiring substrate or on a surface of the wiring substrate, and an electric wiring, which is introduced into the housing part or onto a surface of the housing part, are electrically connected to each other.
    Type: Application
    Filed: September 17, 2021
    Publication date: January 6, 2022
    Applicant: FURUKAWA ELECTRIC CO., LTD.
    Inventors: Maiko ARIGA, Yusuke INABA, Kazuki YAMAOKA, Atsushi IZAWA, Kazuya NAGASHIMA
  • Publication number: 20210376931
    Abstract: An optical module includes: photoelectric elements including first terminal groups; an integrated circuit including second terminal groups and ground terminals; a carrier substrate; a housing; and a common ground pad. Further, the carrier substrate is fixed to one surface of the housing, the carrier substrate includes signal wiring parts and a ground wiring part, the ground wiring part includes terminal pattern parts, a common pattern part, and a coupling part, each of the terminal pattern parts being disposed between the corresponding signal wiring parts and electrically connected with one of the ground terminals, the common pattern part being disposed on a side where the common ground pad is provided on the carrier substrate, the coupling part electrically connecting each terminal pattern part and the common pattern part, and the ground terminals of the integrated circuit are electrically connected with the common ground pad through the ground wiring part.
    Type: Application
    Filed: August 12, 2021
    Publication date: December 2, 2021
    Applicant: FURUKAWA ELECTRIC CO., LTD.
    Inventors: Kazuya NAGASHIMA, Yozo ISHIKAWA, Atsushi IZAWA
  • Publication number: 20210320719
    Abstract: An optical module includes: a laser device; a wavelength detector; a modulator; a modulator driver; a coherent mixer; a photoelectric element; a transimpedance amplifier; and a casing. Further, the laser device is arranged such that the laser device outputs a laser light beam in a direction opposite to a side on which the optical output unit is arranged in the casing.
    Type: Application
    Filed: June 23, 2021
    Publication date: October 14, 2021
    Applicant: FURUKAWA ELECTRIC CO., LTD.
    Inventors: Kazuya NAGASHIMA, Yozo ISHIKAWA, Atsushi IZAWA, Kazuki YAMAOKA
  • Publication number: 20170261701
    Abstract: An optical module includes a first module having a first end surface provided with a first guide hole and a second end surface opposite the first end surface, wherein the first module includes first optical fibers each provided penetrating the first module from the first end surface to the second end surface and having an axial center aligned based on a positional relationship to the first guide hole, and a first optical element having an axial center aligned based on a positional relationship to the first guide hole.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 14, 2017
    Applicant: FURUKAWA ELECTRIC CO., LTD.
    Inventor: Atsushi IZAWA
  • Patent number: 9725514
    Abstract: The present inventors assessed the effect of anti-IL-6 receptor antibodies in suppressing chronic rejection reaction. They assessed the effect of anti-mouse IL-6 receptor antibody (MR16-1) administration in suppressing the chronic rejection reaction using a mouse model for post-heart-transplantation chronic rejection. The result of histopathological analysis of transplanted hearts extirpated 60 days after transplantation revealed that fibrosis of myocardium and vascular stenotic lesions, which are pathological conditions characteristic of the chronic rejection reaction, were significantly suppressed in the MR16-1-treated group as compared to the control group. Thus, MR16-1 administration was demonstrated to have the effect of suppressing chronic rejection reaction. Specifically, the present inventors discovered for the first time that the rejection reaction in the chronic phase after organ transplantation was suppressed by administering an anti-IL-6 receptor antibody.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: August 8, 2017
    Assignees: Shinshu University, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Masafumi Takahashi, Atsushi Izawa
  • Patent number: 9562103
    Abstract: The present inventors assessed the effect of anti-IL-6 receptor antibodies in suppressing chronic rejection reaction. They assessed the effect of anti-mouse IL-6 receptor antibody (MR16-1) administration in suppressing the chronic rejection reaction using a mouse model for post-heart-transplantation chronic rejection. The result of histopathological analysis of transplanted hearts extirpated 60 days after transplantation revealed that fibrosis of myocardium and vascular stenotic lesions, which are pathological conditions characteristic of the chronic rejection reaction, were significantly suppressed in the MR16-1-treated group as compared to the control group. Thus, MR16-1 administration was demonstrated to have the effect of suppressing chronic rejection reaction. Specifically, the present inventors discovered for the first time that the rejection reaction in the chronic phase after organ transplantation was suppressed by administering an anti-IL-6 receptor antibody.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: February 7, 2017
    Assignees: Chugai Seiyaku Kabushiki Kaisha, Shinshu University
    Inventors: Masafumi Takahashi, Atsushi Izawa
  • Patent number: 8623355
    Abstract: The effect of anti-IL-6 receptor antibodies in suppressing cytotoxic T cell induction was examined. The results showed that CTL activity against alloantigens was statistically significantly reduced in mice treated with anti-IL-6 receptor antibodies as compared to mice not treated with antibodies and mice treated with a control antibody. The anti-IL-6 receptor antibody was also administered to recipients of a mouse model for allogenic heart transplantation. As a result, histopathological findings showed that inflammatory cell infiltration into transplanted hearts was suppressed and the survival period of transplanted hearts was significantly prolonged. Thus, the present inventors for the first time discovered that administration of anti-IL-6 receptor antibodies could suppress cytotoxic T cell induction and thereby suppress acute rejection after transplantation.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: January 7, 2014
    Assignees: Chugai Seiyaku Kabushiki Kaisha, National Hospital Organization, Shinshu University
    Inventors: Masaji Okada, Masafumi Takahashi, Atsushi Izawa, Yoshiyuki Ohsugi, Masahiko Mihara
  • Publication number: 20100061986
    Abstract: The present inventors assessed the effect of anti-IL-6 receptor antibodies in suppressing chronic rejection reaction. They assessed the effect of anti-mouse IL-6 receptor antibody (MR16-1) administration in suppressing the chronic rejection reaction using a mouse model for post-heart-transplantation chronic rejection. The result of histopathological analysis of transplanted hearts extirpated 60 days after transplantation revealed that fibrosis of myocardium and vascular stenotic lesions, which are pathological conditions characteristic of the chronic rejection reaction, were significantly suppressed in the MR16-1-treated group as compared to the control group. Thus, MR16-1 administration was demonstrated to have the effect of suppressing chronic rejection reaction. Specifically, the present inventors discovered for the first time that the rejection reaction in the chronic phase after organ transplantation was suppressed by administering an anti-IL-6 receptor antibody.
    Type: Application
    Filed: January 23, 2008
    Publication date: March 11, 2010
    Applicants: Shinshu University, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Masafumi Takahashi, Atsushi Izawa
  • Publication number: 20090263384
    Abstract: The effect of anti-IL-6 receptor antibodies in suppressing cytotoxic T cell induction was examined. The results showed that CTL activity against alloantigens was statistically significantly reduced in mice treated with anti-IL-6 receptor antibodies as compared to mice not treated with antibodies and mice treated with a control antibody. The anti-IL-6 receptor antibody was also administered to recipients of a mouse model for allogenic heart transplantation. As a result, histopathological findings showed that inflammatory cell infiltration into transplanted hearts was suppressed and the survival period of transplanted hearts was significantly prolonged. Thus, the present inventors for the first time discovered that administration of anti-IL-6 receptor antibodies could suppress cytotoxic T cell induction and thereby suppress acute rejection after transplantation.
    Type: Application
    Filed: November 15, 2006
    Publication date: October 22, 2009
    Applicants: NATIONAL HOSPITAL ORGANIZATION, SHINSHU UNIVERSITY, CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Masaji Okada, Masafumi Takahashi, Atsushi Izawa, Yoshiyuki Ohsugi, Masahiko Mihara
  • Publication number: 20090032984
    Abstract: A method for manufacturing optical fibers with filter, wherein a multilayer-film filter is formed at end face of the optical fibers, comprising a process for fixing each of the optical fibers on a fixing jig, a process for polishing the end face of the optical fiber fixed on said fixing jig, a process for film-forming a filter on the end face of the optical fibers after polishing, and a process for taking out said optical fibers from said fixing jigs, respectively, wherein said process for film-forming the filter is performed by forming a fiber bundle in which a plural number of optical fibers after polishing, on which the filter has been film-formed, are tied such that all polished planes are aligned at the end face.
    Type: Application
    Filed: July 9, 2008
    Publication date: February 5, 2009
    Applicant: THE FURUKAWA ELECTRIC CO., LTD.
    Inventors: Masayuki Iwase, Atsushi Izawa, Yozo Ishikawa
  • Patent number: 7412148
    Abstract: An optical component provided with a waveguide groove having, an waveguide holding plane having a surface shape extending along a specified axial direction and capable of holding at least one optical waveguide while positioning it at at least a part of at least one side face thereof; and an opening extending substantially oppositely to the waveguide holding plane and being smaller in width than the outside diameter of at least one optical waveguide in a specified widthwise direction perpendicular to the specified axial direction.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: August 12, 2008
    Assignee: The Furukawa Electric Co., Ltd.
    Inventors: Masayuki Iwase, Atsushi Izawa, Yozo Ishikawa
  • Patent number: 6608725
    Abstract: An optical module, in which an optical device can be mounted and repaired without damaging an electrode on an electronic device side, is provided. A photodiode (1) and a pre-amplifier IC (2) are mounted on a base (stem) (4), and except for that, a relay terminal table (7) is provided. The photodiode (1) and the pre-amplifier IC (2) are connected through the relay terminal table (7) by means of bonding wires (3a, 3b). The relay terminal table (7) is connected via the bonding wire (3a) to an electrode (11) of the photodiode (1), as well as via the bonding wire (3b) to an electrode (12) of the pre-amplifier IC (2). In repairing the photodiode (1) only the bonding wire (3a) is removed for re-wiring, so that the electrode (12) of the pre-amplifier IC can be prevented from being damaged.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: August 19, 2003
    Assignee: The Furukawa Electric Co., Ltd.
    Inventors: Atsushi Izawa, Masayuki Iwase
  • Patent number: 6552083
    Abstract: The present invention relates to an agent for inhibiting diseases associated with chronic rejection after organ transplantation, such as transplanted heart-accelerated coronary arteriosclerosis, containing as an active ingredient N-(3,4-dimethoxycinnamoyl)anthranilic acid represented by formula: or a pharmaceutically acceptable salt thereof, which has an inhibitory effect on vascular thickening in transplanted hearts.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: April 22, 2003
    Assignee: Kissei Pharmaceutical Co., Ltd.
    Inventors: Mitsuaki Isobe, Atsushi Izawa
  • Publication number: 20020067554
    Abstract: An optical module, in which an optical device can be mounted and repaired without damaging an electrode on an electronic device side, is provided. A photodiode (1) and a pre-amplifier IC (2) are mounted on a base (stem) (4), and except for that, a relay terminal table (7) is provided. The photodiode (1) and the pre-amplifier IC (2) are connected through the relay terminal table (7) by means of bonding wires (3a, 3b). The relay terminal table (7) is connected via the bonding wire (3a) to an electrode (11) of the photodiode (1), as well as via the bonding wire (3b) to an electrode (12) of the pre-amplifier IC (2). In repairing the photodiode (1) only the bonding wire (3a) is removed for re-wiring, so that the electrode (12) of the pre-amplifier IC can be prevented from being damaged.
    Type: Application
    Filed: June 26, 2001
    Publication date: June 6, 2002
    Inventors: Atsushi Izawa, Masayuki Iwase