Abstract: An envelope processing apparatus that inserts an enclosure into an envelope includes an envelope conveyor, a flap opener, an enclosure pusher, and circuitry. The envelope conveyor extends in a vertical direction and conveys the envelope to an enclosing position via an envelope conveyance passage as a passage in which the envelope is conveyed. The flap opener opens a flap of the envelope. The enclosure pusher pushes the enclosure toward an opening of a body of the envelope conveyed to the enclosing position with the flap open. The circuitry changes a pushing amount of the enclosure into the envelope and adjusts the pushing amount based on the opening of the body of the envelope within a specified range from an inside to an outside of the body of the envelope.

Abstract: A controller for an internal combustion engine is configured to execute a determination process that determines that a deviation between a first change amount and a second change amount during a fuel cutoff operation is less than or equal to a threshold, and an anomaly diagnosing process that determines that an exhaust purification device is in a detached state when the determination process determines that the deviation is less than or equal to the threshold. The first change amount and the second change amount are change amounts per unit time of the temperature of exhaust gas on the upstream side and the downstream side of the exhaust purification device, respectively. The controller is configured to interrupt the determination process when the upstream-side temperature increases within a determination period.

Abstract: Provided is a medical support arm system including a support arm that is a multilink structure having a plurality of links connected by a joint unit including an actuator, and supports a medical unit. The medical support arm system further includes a control device including an external force estimation unit to estimate an external force acting on the joint unit on the basis of a drive characteristic of the actuator, and a joint control unit to control drive of the joint unit on the basis of an external torque estimated by the external force estimation unit.

Abstract: An input device includes: an operation surface that receives an operation from an operating body that is in close proximity thereto; and first detection electrodes that are arranged along the operation surface and that extend parallel to each other in a first direction. Each of the first detection electrodes has first detection surfaces that are provided side by side in the first direction and a first current path portion that extends linearly in the first direction and via which the first detection surfaces are connected to each other; and each of the first detection surfaces has one or more second current path portions and a pair of first connection portions via which the one or more second current path portions and the first current path portion are connected in parallel to each other.

Abstract: An envelope processing apparatus conveys an envelope to an enclosing position and encloses an enclosure on which specific information is formed at a formation position. The enclosing device includes: an envelope conveyor to convey the enclosure to the enclosing position to insert the enclosure into the envelope; a sensor to acquire, as an image, a structure of the envelope during conveyance, and acquire transparent-portion information indicating a position of a transparent portion in the envelope; an envelope holder to hold the envelope in a state in which the enclosure is insertable; and control circuitry to output position adjustment information for adjusting a position of the envelope in a width direction of the envelope at the enclosing position or a position of the specific information in a conveyance direction of the envelope, based on relative positions between the formation position of the specific information and the position of the transparent portion.

Abstract: A pancreatic cancer detection method is provided, including: (a) bringing extracellular vesicles, which are in a body fluid sample derived from a subject into contact with one or more kinds of lectins; (b) measuring an amount of the extracellular vesicles bound to the one or more kinds of lectins after (a); and (c) evaluating the presence of pancreatic cancer in the subject based on the amount of the extracellular vesicles measured in (b). In addition, a pancreatic cancer detection kit is provided, including: a solid-phase carrier on which one or more kinds of lectins are immobilized; and an antibody specifically binding to a pan-extracellular vesicle membrane protein or an antigen-binding fragment thereof.

Abstract: A train jolt determination system includes: a portable terminal capable of being held in a train and configured to acquire position information on the train, detect the acceleration of the train, and capture an image of the scene around the train; a storage section configured to associate the position information, acceleration information indicative of a detection result of the acceleration, and image information indicative of the scene and store the position information, the acceleration information, and the image information; and a jolt amount calculation section configured to calculate an amount of jolting of the body based on the acceleration information. In a case where the body is determined to have jolted based on the amount of jolting, position information associated with acceleration information used for the determination of jolting is supplemented with image information associated with the acceleration information, and a position where the body has jolted is estimated.

Abstract: An optical aberration correction program causing a computer (3) to execute: obtaining phases of a plurality of provisional optical transfer functions of an optical system (10) corresponding to a plurality of provisional optical aberration amounts of the optical system; generating a plurality of three-dimensional phase-modulated images by deconvolving a three-dimensional original image of a sample (12) including an optical aberration of the optical system (10) with each of the phases of the plurality of provisional optical transfer functions; obtaining an optimal theoretical three-dimensional point spread function based on indices of luminance values of the plurality of three-dimensional phase-modulated images; and calculating a three-dimensional correction image by deconvolving the three-dimensional original image or another three-dimensional original image that includes the optical aberration of the optical system (10) and is different from the three-dimensional original image with an optimal optical transfe

Abstract: Provided is a T cell receptor containing, as ? chain complementarity determining regions, respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 1 to 3, or respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 4 to 6, as ? chain complementarity determining regions, respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 7 to 9, or respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 10 to 12, and capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24.

Abstract: A gradient magnetic field sensor includes: an AC power supply connection terminal to which a first power supply terminal included in an AC power supply is connected; a first magnetic core connected between the connection terminal and the ground; a second magnetic core connected in parallel with the first magnetic core between the connection terminal and ground; an AC current control unit connected between the connection terminal and at least one of the first magnetic core and the second magnetic core and configured to control an AC current flowing through at least one of the first and second magnetic core; a first detection coil wound around the first magnetic core; a second detection coil wound around second magnetic core and differentially-connected with the first detection coil; and a detection circuit that detects a voltage difference between first voltage output from first detection coil and second voltage output from the second.

Abstract: A capacitance detection device for detecting a capacitance between a detection electrode and an object in proximity to the detection electrode includes the detection electrode configured to detect a capacitance between the detection electrode and the object, an active shield electrode disposed in proximity to the detection electrode, a voltage output circuit for outputting an alternating voltage to be supplied to the active shield electrode, a first adjustment circuit for adjusting an amplitude of an alternating voltage output from the voltage output circuit, and a first operational amplifier for amplifying and outputting a voltage difference between an inverting input terminal thereof connected to one end of the detection electrode and a non-inverting input terminal thereof to which an alternating voltage adjusted by the first adjustment circuit is applied. The detection electrode has, between one end and the other end thereof, a resistance value from 5 k? to 270 k?.

Abstract: N (n is a natural number) power converters operate in accordance with a drive signal to generate a power to be supplied to a load. Multi-redundant A/D converters convert an analog detection value from the power converters into digital values. First and second controllers operate in parallel and each generate a drive signal of the power converters using the digital values from the A/D converters. A system selector selects one controller in accordance with an abnormality detection result of the first and second controllers. Each of n output selectors receives the drive signals from both of the first and second controllers and outputs the drive signal from the one controller selected by the system selector to the power converters.

Abstract: A capacitance detection device includes at least one detection electrode, a shield electrode disposed in close vicinity of the detection electrode, an AC signal source that supplies an AC signal to the shield electrode, a detection circuit that detects capacitance between a physical object in close vicinity of the detection electrode and the detection electrode on the basis of a detection signal output from the detection electrode and the AC signal output from the AC signal source, and a phase adjustment circuit provided between the AC signal source and the shield electrode. The phase adjustment circuit advances the phase of the AC signal output from the AC signal source.

Abstract: Provided is a T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24. A T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 28 or a complex of the peptide and HLA-A02. Disclosed T cell receptors are useful in treating or avoiding cancers which are associated with expression of glypican-3.

Abstract: A first imaging unit 71 generates a first image a first image by taking an object to be inspected. A guide display unit 72 determines the object to be inspected from the first image by using a model for determining an object to be inspected from an image, and displays an illustration representing the object to be inspected as a guide. A second imaging unit 73 generates a second image by superimposing on the guide, and taking the object to be inspected with a recognizable marker regardless of color of an appearance of an object to be inspected, attached in a vicinity of a defect. A defect position determination unit 74 determines a position of the defect included in the object to be inspected based on a positional relationship between the illustration and the marker included in the second image. An information collecting unit 75 collects defect information associated with a type of the object to be inspected and the position of the defect.

Abstract: An input device includes: an operation surface that receives an operation from an operating body that is in close proximity thereto; and first detection electrodes that are arranged along the operation surface and that extend parallel to each other in a first direction. Each of the first detection electrodes has first detection surfaces that are provided side by side in the first direction and a first current path portion that extends linearly in the first direction and via which the first detection surfaces are connected to each other; and each of the first detection surfaces has one or more second current path portions and a pair of first connection portions via which the one or more second current path portions and the first current path portion are connected in parallel to each other.

Abstract: A pancreatic cancer detection method is provided, including: (a) bringing extracellular vesicles, which are in a body fluid sample derived from a subject into contact with one or more kinds of lectins; (b) measuring an amount of the extracellular vesicles bound to the one or more kinds of lectins after (a); and (c) evaluating the presence of pancreatic cancer in the subject based on the amount of the extracellular vesicles measured in (b). In addition, a pancreatic cancer detection kit is provided, including: a solid-phase carrier on which one or more kinds of lectins are immobilized; and an antibody specifically binding to a pan-extracellular vesicle membrane protein or an antigen-binding fragment thereof.

Abstract: A capacitance detection part simultaneously receive input of electric charges stored at one electrode, from a plurality of terminals provide to the one electrode. As a result of the simultaneous input, partial electric charges stored between an object and an overlapping portion of one electrode overlapping one segment are distributed as distribution electric charges to each of the plurality of terminals in accordance with a conductance from the overlapping portion to each of the plurality of terminals. The capacitance detection part generates detection data corresponding to the distribution electric charges, for each of N terminals. The element data configuration part configures M pieces of element data corresponding to M segments, on the basis of the N pieces of detection data.

Abstract: An object of the present invention is to provide a magnetic sensor that can reduce influences of a disturbance magnetic field while ensuring high detection sensitivity. The magnetic sensor includes a sensor chip 20 having an element formation surface 20S on which magnetic detection elements MR3, MR4 are formed, a first magnetic member 31 placed on the element formation surface 20S and having a first height H1 as a height from the element formation surface 20S, and a second magnetic member 32 located on an opposite side of the magnetic detection elements MR3, MR4 to the first magnetic member 31 and having a second height H2 lower than the first height H1. According to the present invention, because the height H2 of the second magnetic member 32 is lower than that of the first magnetic member 31, a detection magnetic field attracted to the second magnetic member 32 can be reduced while a disturbance magnetic field is shielded by the second magnetic member 32.

Abstract: An input device includes a detector that includes a base having a polyhedral shape and detection electrodes that are provided on some or all sides of the base and detect proximity of an operator, and a guide that has a shape surrounding the detector and guides an input operation performed by the operator.