Patents by Inventor Atsushi Matsuo

Atsushi Matsuo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240175674
    Abstract: A laser interferometer includes: a laser light source configured to emit laser light toward an object; an optical modulator including a vibrator configured to modulate the laser light using the vibrator and superimpose a modulation signal on the laser light; a photodetector configured to receive the laser light including a sample signal derived from the object and the modulation signal, and to output a light reception signal; a demodulation circuit configured to demodulate the sample signal from the light reception signal based on a reference signal; and an oscillation circuit configured to operate using the vibrator as a signal source and output the reference signal to the demodulation circuit. The vibrator includes a vibration substrate having a base portion and a vibration unit coupled to the base portion. The vibration unit vibrates along an in-plane direction of the vibration substrate and includes a side surface intersecting with the in-plane direction.
    Type: Application
    Filed: November 29, 2023
    Publication date: May 30, 2024
    Inventors: Kohei YAMADA, Atsushi MATSUO
  • Publication number: 20240176157
    Abstract: An optical modulator includes: a vibrator configured to perform flexural vibration along a first direction; and a diffraction grating disposed in the vibrator and having a plurality of grooves arranged in parallel along the first direction. A frequency of laser light incident on the diffraction grating is shifted. In addition, it is preferable that the vibrator includes a base portion, a first vibration arm, and a second vibration arm disposed side by side along the first direction and coupled to the base portion, the first vibration arm and the second vibration arm perform the flexural vibration along the first direction, and the diffraction grating is disposed on at least one of the first vibration arm and the second vibration arm.
    Type: Application
    Filed: November 29, 2023
    Publication date: May 30, 2024
    Inventors: Kohei YAMADA, Atsushi MATSUO
  • Publication number: 20240166689
    Abstract: An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
    Type: Application
    Filed: September 1, 2023
    Publication date: May 23, 2024
    Inventors: Shiori KARIYUKI, Takeo IIDA, Miki KOJIMA, Ryuichi TAKEYAMA, Mikimasa TANADA, Tetsuo KOJIMA, Hitoshi IIKURA, Atsushi MATSUO, Takuya SHIRAISHI, Takashi EMURA, Kazuhiko NAKANO, Koji TAKANO, Kousuke ASOU, Takuya TORIZAWA, Ryusuke TAKANO, Nozomi HISADA, Naoaki MURAO, Atsushi OHTA, Kaori KIMURA, Yusuke YAMAGISHI, Tatsuya KATO
  • Patent number: 11990887
    Abstract: The vibrator device includes a vibrator element, a relay substrate, a base, an element-side bonding member for bonding the vibrator element and the relay substrate to each other, and a base-side bonding member for bonding the base and the relay substrate to each other. Further, the element-side bonding member has a first bonding member and s second bonding member arranged side by side along an A axis. Further, an X axis of a first quartz crystal substrate provided to the vibrator element is parallel to the A axis, and a second quartz crystal substrate provided to the relay substrate is a Z-cut quartz crystal substrate.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: May 21, 2024
    Assignee: SEIKO EPSON CORPORATION
    Inventors: Ryuta Nishizawa, Shinya Aoki, Atsushi Matsuo
  • Publication number: 20240162879
    Abstract: A vibrator element includes a vibrating section having a rectangular shape in a plan view and including a first principal surface, a second principal surface, and an excitation portion sandwiched by a first excitation electrode and a second excitation electrode and making a thickness-shear vibration, a coupling arm extending from a corner part of the vibrating section in a first direction, and a supporting arm having a side surface at one end part side coupled to the coupling arm and extending in a second direction crossing the first direction, wherein the supporting arm includes a first supporting electrode electrically coupled to the first excitation electrode and bonded to a container via an adhesive member, and a width of the coupling arm along the second direction is four or more times a thickness of the excitation portion along a third direction crossing the first direction and the second direction and equal to or smaller than a length from an end part of the supporting arm at the coupling arm side to t
    Type: Application
    Filed: November 15, 2023
    Publication date: May 16, 2024
    Inventors: Norihito MATSUKAWA, Atsushi MATSUO, Kensaku ISOHATA
  • Publication number: 20240148287
    Abstract: A biological information measurement device includes: a light-emitting unit including a first light-emitting element that emits red light and a second light-emitting element that emits infrared light; a light-receiving unit configured to receive the red light emitted from the first light-emitting element and the infrared light emitted from the second light-emitting element and generate a first light-receiving signal based on the red light and a second light-receiving signal based on the infrared light; and a controller configured to calculate an oxygen saturation concentration. The controller is configured to calculate the oxygen saturation concentration using the first light-receiving signal and the second light-receiving signal, calculate correlation data using the first light-receiving signal and the second light-receiving signal, and determine the oxygen saturation concentration based on the correlation data.
    Type: Application
    Filed: November 8, 2023
    Publication date: May 9, 2024
    Inventors: Akira IKEDA, Atsushi MATSUO
  • Publication number: 20240148821
    Abstract: The present inventors found cyclic peptide compounds that interact with Ras, and pharmaceutical compositions containing the cyclic peptide compounds or salts thereof, or solvates thereof.
    Type: Application
    Filed: May 6, 2022
    Publication date: May 9, 2024
    Inventors: Mikimasa TANADA, Koji TAKANO, Atsushi MATSUO, Minoru TAMIYA, Aya CHIYODA, Toshiya ITO, Takeo IIDA, Atsushi OHTA
  • Publication number: 20240113687
    Abstract: A resonator element includes an AT-cut quartz crystal substrate having a first surface that is a front surface and a second surface that is a rear surface with respect to the front surface, the two surfaces extending along the axes X and Z? of a quartz crystal, and further having side surfaces that link the first and second surfaces to each other, a first excitation electrode disposed at the first surface, a first extraction electrode disposed at the first surface and coupled to the first excitation electrode, a second excitation electrode disposed at the second surface, and a second extraction electrode disposed at the second surface and coupled to the second excitation electrode. The side surfaces include a first side surface located at one side of the direction of the axis X, and second and third side surfaces that intersect with the first side surface. At least one of the first and second extraction electrodes is disposed at and extends along the first side surface.
    Type: Application
    Filed: September 26, 2023
    Publication date: April 4, 2024
    Inventors: Atsushi Matsuo, Katsuhiko Maki
  • Publication number: 20240088859
    Abstract: A method for manufacturing a vibrator includes: a preparation process of preparing a quartz-crystal wafer including a vibrator and a holding portion, the vibrator including a support portion and a vibration part arranged side by side along a first direction, the holding portion being coupled to one end portion of the support portion in a second direction intersecting the first direction; an adhering process of fixing at least the support portion and the holding portion of the quartz-crystal wafer to a film via an adhesive; and a singulation process of stretching the film along the second direction, and separating and singulating the vibrator from the holding portion.
    Type: Application
    Filed: August 29, 2023
    Publication date: March 14, 2024
    Inventors: Atsushi Matsuo, Katsuhiko Maki
  • Publication number: 20240066553
    Abstract: A vibrator device includes a vibrator element including a vibrator section having a rectangular shape in a plan view, a linkage arm extending from a corner portion of the vibrator section in a first direction, and a support arm extending from the linkage arm in a second direction that intersects with the first direction, a container that houses the vibrator element, and an adhesive member that is shifted from the linkage arm in the second direction, is bonded to the support arm of the vibrator element, and bonds the vibrator element to the container, and an adhesive area of the region where the adhesive member is bonded to the support arm is greater than or equal to 20% of the area of the support arm in the plan view.
    Type: Application
    Filed: August 23, 2023
    Publication date: February 29, 2024
    Inventors: Atsushi MATSUO, Kensaku ISOHATA, Norihito MATSUKAWA
  • Publication number: 20240072760
    Abstract: A resonator device includes a resonator element, a container configured to house the resonator element, and a bonding member configured to bond the resonator element and the container to each other, wherein the resonator element has a vibrating part which has a first principal surface provided with a first excitation electrode, a second principal surface provided with a second excitation electrode and having an obverse-reverse relationship with the first principal surface, and a side surface extending in a first direction along a displacement direction of a thickness-shear vibration excited by the first excitation electrode and the second excitation electrode, and which has a longitudinal direction in a second direction as a direction crossing the first direction, a coupling arm extending in the second direction from the side surface of the vibrating part, and a support part which includes a first support arm extending in the first direction from the coupling arm, which extends in the first direction, and whi
    Type: Application
    Filed: August 30, 2023
    Publication date: February 29, 2024
    Inventors: Atsushi MATSUO, Kensaku ISOHATA, Norihito MATSUKAWA
  • Patent number: 11891457
    Abstract: An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: February 6, 2024
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Shiori Kariyuki, Takeo Iida, Miki Kojima, Ryuichi Takeyama, Mikimasa Tanada, Tetsuo Kojima, Hitoshi Iikura, Atsushi Matsuo, Takuya Shiraishi, Takashi Emura, Kazuhiko Nakano, Koji Takano, Kousuke Asou, Takuya Torizawa, Ryusuke Takano, Nozomi Hisada, Naoaki Murao, Atsushi Ohta, Kaori Kimura, Yusuke Yamagishi, Tatsuya Kato
  • Publication number: 20240039509
    Abstract: A vibrator element includes a vibrator section that has a first principal surface, a second principal surface, a first side surface, and a second side surface, a support section that is disposed at a distance from the vibrator section and has a first support side surface facing the first side surface of vibrator section and a second support side surface extending in a direction that intersects with the direction in which the first support side surface extends, and a linkage section that has a first linkage surface coupled to the first side surface and the first support side surface and a second linkage surface coupled to the second side surface and the second support side surface, and the first linkage surface has a configuration in which at least one of a first section coupled to the first side surface and a second section coupled to the first support side surface has a curved surface.
    Type: Application
    Filed: July 27, 2023
    Publication date: February 1, 2024
    Inventors: Kensaku ISOHATA, Atsushi MATSUO, Norihito MATSUKAWA
  • Publication number: 20240039511
    Abstract: A vibrator includes a vibrator section, a support section, a linkage section, a first excitation electrode that is provided at a first principal surface, a second excitation electrode that is provided at a second principal surface and induces along with the first excitation electrode thickness-shear vibration that vibrates along a direction X, a first support electrode that is provided at the support section and electrically coupled to the first excitation electrode, a second support electrode that is provided at the support section and electrically coupled to the second excitation electrode, a first draw-out wiring line that is drawn from the first excitation electrode along a direction Z and electrically couples the first excitation electrode to the first support electrode, and a second draw-out wiring that is drawn from the second excitation electrode along the direction Z and electrically couples the second excitation electrode to the second support electrode.
    Type: Application
    Filed: July 27, 2023
    Publication date: February 1, 2024
    Inventors: Kensaku ISOHATA, Atsushi MATSUO, Norihito MATSUKAWA
  • Publication number: 20230382912
    Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.
    Type: Application
    Filed: August 11, 2023
    Publication date: November 30, 2023
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hitoshi YOSHINO, Satoshi TSUCHIYA, Atsushi MATSUO, Tsutomu SATO, Masahiro NISHIMOTO, Kyoko OGURI, Hiroko OGAWA, Yoshikazu NISHIMURA, Yoshiyuki FURUTA, Hirotaka KASHIWAGI, Nobuyuki HORI, Takuma KAMON, Takuya SHIRAISHI, Shoshin YOSHIDA, Takahiro KAWAI, Satoshi TANIDA, Masahide AOKI
  • Patent number: 11814381
    Abstract: The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: November 14, 2023
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hitoshi Yoshino, Satoshi Tsuchiya, Atsushi Matsuo, Tsutomu Sato, Masahiro Nishimoto, Kyoko Oguri, Hiroko Ogawa, Yoshikazu Nishimura, Yoshiyuki Furuta, Hirotaka Kashiwagi, Nobuyuki Hori, Takuma Kamon, Takuya Shiraishi, Shoshin Yoshida, Takahiro Kawai, Satoshi Tanida, Masahide Aoki
  • Patent number: 11722098
    Abstract: A vibrator includes: a vibration element that includes a pair of first excitation electrodes formed at the first vibration portion, a pair of second excitation electrodes formed at the second vibration portion, and a pair of third excitation electrodes formed at the third vibration portion, in which one second excitation electrode of the pair of second excitation electrodes is formed at a first inclined surface that is inclined with respect to two main surfaces, and one third excitation electrode of the pair of third excitation electrodes is formed at a second inclined surface that is inclined with respect to the two main surfaces and the first inclined surface; and a package that houses the vibration element. The vibration element includes a fixing portion to be fixed to the package. The fixing portion is provided between the first vibration portion and the second and third vibration portions.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: August 8, 2023
    Assignee: SEIKO EPSON CORPORATION
    Inventors: Atsushi Matsuo, Ryuta Nishizawa
  • Publication number: 20230198489
    Abstract: A method for manufacturing a resonator element includes: a substrate preparation step of preparing a substrate; an etching step of performing an etching process on the substrate to form a resonator element, a frame portion, and a holding portion that couples the resonator element and the frame portion; and a break-off step of breaking off the resonator element from the frame portion. The holding portion includes a narrow portion in which a part of a width is narrow. The width of the narrow portion is minimum at a position closer to a resonator element side than at a center of the holding portion. In a cross-sectional view, an angle formed by a side surface of the narrow portion with respect to a flat surface of the holding portion is in a range of 85° or more and 95° or less. The etching process is dry etching.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 22, 2023
    Inventors: Atsushi Matsuo, Kensaku Isohata, Masaya Kanno
  • Publication number: 20230151060
    Abstract: The present inventors found cyclic peptide compounds that interact with Ras, and non-natural amino acids useful for the production of the cyclic peptide compounds. The inventors also found that the cyclic peptide compounds inhibit the binding between Ras and SOS. In addition, the inventors found specific non-natural amino acids contained in the cyclic peptide compounds and methods for production thereof.
    Type: Application
    Filed: November 5, 2020
    Publication date: May 18, 2023
    Inventors: Mikimasa TANADA, Koji TAKANO, Atsushi MATSUO, Minoru TAMIYA, Aya CHIYODA, Toshiya ITO, Takeo IIDA
  • Patent number: 11651264
    Abstract: Systems and methods that address an optimized method to improve systems and methods for handling inequality constraints in mixed binary optimization problems on quantum computers and to solve local optima which significantly improves system performance. Embodiments employ an improved methodology that can optimize parameters, determine an optimal slack variable and optimize variational parameters for fixed slack variables. This procedure allows to move out of local minima, solve an optimization and improve the system performance by providing optimal results. These embodiments also extend to variational hybrid quantum/classical algorithms for gate-based quantum computers.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: May 16, 2023
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stefan Woerner, Daniel Josef Egger, Jennifer Ranae Glick, Takashi Imamichi, Atsushi Matsuo