Abstract: It is intended to provide a kit or a device for the detection of lung cancer and a method for detecting lung cancer. The present invention provides a kit or a device for the detection of lung cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting lung cancer, comprising measuring the miRNA in vitro.

Abstract: Provided is an information processing device that includes a planning unit that sets a joining route on the basis of information about at least one of a planned route of a user mobile unit that uses a service or a planned route of a provider mobile unit that provides the service, the joining route being a zone for the user mobile unit and the provider mobile unit to receive and provide the service, and makes a movement plan including at least one of a route plan for the user mobile unit or a route plan for the provider mobile unit based on the joining route. The information processing device further includes a service provision unit that controls provision of the service so that the user mobile unit and the provider mobile unit receive and provide the service while moving on the joining route.

Abstract: It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting liver cancer, comprising measuring the miRNA in vitro.

Abstract: The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the miRNA in vitro.

Abstract: This invention relates to a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for the detection of stomach cancer, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting stomach cancer, comprising measuring the miRNA(s) in vitro.

Abstract: It is intended to provide a kit or a device for the detection of colorectal cancer and a method for detecting colorectal cancer. The present invention provides a kit or a device for the detection of colorectal cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting colorectal cancer, comprising measuring the miRNA in vitro.

Abstract: This application provides a kit or a device for the detection of early pancreatic cancer or a pancreatic cancer precursor lesion, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting early pancreatic cancer or a pancreatic cancer precursor lesion, comprising measuring an expression level(s) of the miRNA(s) in vitro.

Abstract: A laser beam irradiation apparatus including: a plurality of laser light sources emitting first laser beams; and a light-condensing optics system having an incident face on which the first laser beams are made incident and performing an optical operation on the first laser beams to emit second laser beams. The plurality of laser light sources are configured to emit the first laser beams so that beam diameters are expanded towards the incident face. Each first laser beam overlaps at least one of the other laser beams on the incident face. The light-condensing optics system is configured so that beam diameters of second laser beams emitted from the light-condensing optics system are minimal on a target face, and a distance between a center of each second laser beam and the optical axis on the target face is smaller than a beam radius of each second laser beam on the target face.

Abstract: This application provides a kit or a device for the detection of early pancreatic cancer or a pancreatic cancer precursor lesion, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting early pancreatic cancer or a pancreatic cancer precursor lesion, comprising measuring an expression level(s) of the miRNA(s) in vitro.

Abstract: We achieved the present invention on the basis of the finding that an excellent therapeutic effect against pancreatic cancer can be obtained by administering an IL-6 inhibitor and an antimetabolite to pancreatic cancer patients. We also found that metastatic lesions from human pancreatic cancer can be reduced and ascites can be eliminated.

Abstract: A threat coping system (10) is provided with a threat coping device (300) that copes with a coping target (30) and a control device (200) that controls the threat coping device. The control device (200) is provided with a no-coping area setting means (514) and a coping instruction means (526). The no-coping area setting means (514) sets a no-coping area (12) based on information of a no-coping target that is not to cope with. The coping instruction means (526) generates an instruction signal, that instructs the threat coping device to cope a coping target, based on the no-coping area.

Abstract: We achieved the present invention on the basis of the finding that an excellent therapeutic effect against pancreatic cancer can be obtained by administering an IL-6 inhibitor and an antimetabolite to pancreatic cancer patients. We also found that metastatic lesions from human pancreatic cancer can be reduced and ascites can be eliminated.

Abstract: An underwater acoustic deception system deceives a sensor installed on a threat existing in or on water by acoustic effect in order to protect ships from the threat. The underwater acoustic deception system is provided with a control device, a laser oscillator and emission optical system. The control device determines a focusing position to focus a laser beam (50) in water in order to generate bubbles (70) at a desired position with a desired scale and emission parameters of the laser beam (50). The laser oscillator generates the laser beam (50) configured to focus in water and generate bubbles. The emission optical system emits the generated laser beam (50) to the focusing position. The underwater acoustic deception system deceives an arbitrary sensor existing in the water by acoustic effect of the bubbles (70) on the surroundings.

Abstract: A laser beam is condensed in a close position to a target object in underwater so as to generate an air bubble or plasma. The target object is efficiently destroyed by a shock by the air bubble or the plasma.

Abstract: A driving optical system is used to observe a disturbance of a wavefront of reference light received from a target and generate a wavefront in a conjugate relationship with the wavefront. A plurality of control signals are generated on a basis of a plurality of Zernike coefficients calculated as a Zernike polynomial which approximates the wavefront disturbance in order to respectively drive a plurality of deformable mirrors included in the driving optical system. An adaptive optical system is provided which can optically compensate a wavefront disturbance derived from an atmospheric fluctuation even in a case of radiating laser light to a target moving at a high speed.

Abstract: An optical correction is predictively performed based on a result of AI learning previously performed by use of learning data including measurement data. The optical compensation system is provided with wavefront correction optics, a sensor and a controller. The wavefront correction optics corrects a wavefront of light that passes through a given optical path. The sensor obtains environmental information in the optical path. The controller calculates, based on the environmental information, a predicted wavefront disturbance of the light that has passed through the optical path and controls the wavefront correction optics so as to cancel the predicted wavefront disturbance.

Abstract: Changing non-mechanically a direction of irradiating a laser. The laser apparatus includes an optical device and a laser irradiation device. The optical device has two reflection mirrors facing each other, and a waveguide between the two reflection mirrors. The laser irradiation device irradiates the optical device with laser. The optical device is configured so that at least a portion of the laser travels on the waveguide by being reflected by the two reflection mirrors in order. The optical device has an output surface that emits a portion of the laser. The laser irradiation device has a plurality of irradiation parts including a first irradiation part that irradiates a first laser and a second irradiation part that irradiates a second laser. When viewed from a normal direction of the output surface, a traveling direction of the first laser is not parallel to a traveling direction of the second laser.

Abstract: An optical system that obtains characteristics of a transmission path in atmosphere, when laser light propagates through this transmission path, at a place separated from this transmission path and before the propagation, and corrects wavefront of the laser light based on the obtained characteristics, is provided. The optical system is provided with an irradiation device and an atmospheric characteristics obtaining system. The irradiation device irradiates an external target with light via a first optical path. The atmospheric characteristics obtaining system is arranged in a second optical path separated from the first optical path and obtains characteristics of atmospheric environment in the first optical path with respect to the irradiated light. The irradiation device is provided with wavefront correction optics. The wavefront correction optics correct wavefront of the irradiated light based on the obtained characteristics.

Abstract: A laser beam is condensed in a close position to a target object in underwater so as to generate an air bubble or plasma. The target object is efficiently destroyed by a shock by the air bubble or the plasma.

Abstract: A solid obstacle is removed with a high-power laser beam to establish a transmission path for a spatial laser communication. When a space in which the laser beam is transmitted is blocked off by the solid obstacle, the spatial laser communication cannot be carried out.