Abstract: A solid obstacle is removed with a high-power laser beam to establish a transmission path for a spatial laser communication. When a space in which the laser beam is transmitted is blocked off by the solid obstacle, the spatial laser communication cannot be carried out.

Abstract: A laser irradiation apparatus is provided with a controller that calculates at least one predicted movement position into which a target is predicted to move at a specific time in future, a transmission laser source that generates a transmission laser, irradiation optics configured to emit the transmission laser to the target and emit search laser to the predicted movement position and wavefront correction optics. The wavefront correction optics are configured to correct a wavefront of the transmission laser at the specific time based on observation light that returns when the search laser is emitted to the predicted movement position.

Abstract: A laser irradiation apparatus that efficiently carries out processes such as target detection. The laser irradiation apparatus (1) is provided with a laser array (10), a detector (20) and a controller (30). The laser array is provided with a plurality of laser oscillators including a first laser oscillator (11) that irradiates first detection laser light and a second laser oscillator (11) that irradiates second dealing laser light. The detector obtains detection information based on reflected light (503) that is the first detection laser light reflected by a target (2). The controller estimates a position of the target based on the detection information and generates a second dealing signal that instructs to irradiate the second dealing laser light to the estimated position of the target. The second laser oscillator irradiates dealing laser light to the estimated position of the target based on the second dealing signal.

Abstract: This invention provides a kit or a device for the detection of pancreatic cancer, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting pancreatic cancer, comprising measuring the miRNA(s) in vitro.

Abstract: The present technology relates to an information processing device, an information processing method, a program, and a moving object that enable provision of a service from a mobile unit to another mobile unit. An information processing device includes: a planning unit that sets a joining route on the basis of information about at least one of a planned route of a user mobile unit that is a mobile unit to use a service or a planned route of a provider mobile unit that is a mobile unit to provide the service, the joining route being a zone for the user mobile unit and the provider mobile unit to receive and provide the service, and makes a movement plan including at least one of a route plan for the user mobile unit or a route plan for the provider mobile unit in accordance with the joining route; and a service provision unit that controls provision of the service so that the user mobile unit and the provider mobile unit receive and provide the service while moving on the joining route.

Abstract: An underwater acoustic deception system deceives a sensor installed on a threat existing in or on water by acoustic effect in order to protect ships from the threat. The underwater acoustic deception system is provided with a control device, a laser oscillator and emission optical system. The control device determines a focusing position to focus a laser beam (50) in water in order to generate bubbles (70) at a desired position with a desired scale and emission parameters of the laser beam (50). The laser oscillator generates the laser beam (50) configured to focus in water and generate bubbles. The emission optical system emits the generated laser beam (50) to the focusing position. The underwater acoustic deception system deceives an arbitrary sensor existing in the water by acoustic effect of the bubbles (70) on the surroundings.

Abstract: A method for predicting responsiveness to a HER2-directed therapy by assessing HER2 heterogeneity in a tumor includes contacting a sample of the tumor with a biomarker-specific reagent that specifically binds to HER2 protein and detecting HER2 protein in the sample, contacting the sample of the tumor with a first nucleic acid probe that specifically binds HER2 genomic DNA and detecting HER2 gene amplification status in the sample, contacting the sample of the tumor with a second nucleic acid probe that specifically binds HER2 RNA and detecting HER2 RNA status in the sample scoring the HER2 protein (IHC), HER2 gene (DISH), and HER2 RNA (RNA-ISH), predicting that the tumor is responsive to the HER2-directed therapy if the tumor reveals a first foci having a first score and a second score, in which the first score and the second score are not the same.

Abstract: This invention provides a kit or a device for the detection of pancreatic cancer, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting pancreatic cancer, comprising measuring the miRNA(s) in vitro.

Abstract: A method of irradiating an electromagnetic pulse includes specifying a position of a target having electronic equipment; setting the light-condensing point based on the position of the target; and condensing the laser beam to generate plasma in the light-condensing point such that the electromagnetic pulse generated from the plasma is irradiated to the electronic equipment. In this way, a method and system for irradiating an electromagnetic pulse are realized which can irradiate the electromagnetic pulse of a large output while restraining diffusion of the electromagnetic pulse.

Abstract: It is intended to provide a kit or a device for the detection of esophageal cancer and a method for detecting esophageal cancer. The present invention provides a kit or a device for the detection of esophageal cancer, comprising nucleic acid(s) capable of specifically binding to miRNA(s) in a sample f a subject, and a method for detecting esophageal cancer, comprising measuring the miRNA in vitro.

Abstract: The present inventors discovered that neural invasion is suppressed by inhibiting IL-6 in a model for neural invasion of pancreatic cancer, and completed the present invention. The present inventors also demonstrated that: an IL-6 receptor is expressed in cells of human pancreatic cancer cell lines; and IL-6 enhances the chemotactic and migratory activities and intracellular signaling of pancreatic cancer cells; and thus pancreatic cancer can be treated by inhibiting IL-6. Furthermore, the present inventors found that neural invasion of human pancreatic cancer can be suppressed, from the results of administering IL-6 inhibitors to neural invasion model mice.

Abstract: A laser beam irradiation apparatus including: a plurality of laser light sources emitting first laser beams; and a light-condensing optics system having an incident face on which the first laser beams are made incident and performing an optical operation on the first laser beams to emit second laser beams. The plurality of laser light sources are configured to emit the first laser beams so that beam diameters are expanded towards the incident face. Each first laser beam overlaps at least one of the other laser beams on the incident face. The light-condensing optics system is configured so that beam diameters of second laser beams emitted from the light-condensing optics system are minimal on a target face, and a distance between a center of each second laser beam and the optical axis on the target face is smaller than a beam radius of each second laser beam on the target face.

Abstract: The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the miRNA in vitro.

Abstract: Observing a disturbance of a wavefront of reference light received from a target and generating a wavefront in a conjugate relationship with the wavefront by use of a driving optical system. Generating a plurality of control signals on a basis of a plurality of Zernike coefficients calculated as a Zernike polynomial which approximates the wavefront disturbance in order to respectively drive a plurality of deformable mirrors included in the driving optical system. Providing an adaptive optical system which can optically compensate a wavefront disturbance derived from an atmospheric fluctuation even in a case of radiating laser light to a target moving at a high speed.

Abstract: It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting liver cancer, comprising measuring the miRNA in vitro.

Abstract: This invention relates to a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for the detection of stomach cancer, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting stomach cancer, comprising measuring the miRNA(s) in vitro.

Abstract: It is intended to provide a kit or a device for the detection of lung cancer and a method for detecting lung cancer. The present invention provides a kit or a device for the detection of lung cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting lung cancer, comprising measuring the miRNA in vitro.

Abstract: It is intended to provide a kit or a device for the detection of colorectal cancer and a method for detecting colorectal cancer. The present invention provides a kit or a device for the detection of colorectal cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting colorectal cancer, comprising measuring the miRNA in vitro.

Abstract: The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the miRNA in vitro.

Abstract: This application provides a kit or a device for the detection of early pancreatic cancer or a pancreatic cancer precursor lesion, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting early pancreatic cancer or a pancreatic cancer precursor lesion, comprising measuring an expression level(s) of the miRNA(s) in vitro.