Patents by Inventor Avetik Markosyan

Avetik Markosyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12677849
    Abstract: Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2, reb M2, and reb I are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.
    Type: Grant
    Filed: January 16, 2023
    Date of Patent: July 14, 2026
    Assignee: PureCircle Sdn. Bhd.
    Inventors: Avetik Markosyan, Indra Prakash, Cyrille Jarrin, Aurélien Badie, Robert Ter Halle, Cynthia Curran, Daniel Auriol
  • Patent number: 12677848
    Abstract: Stevia flavor compositions comprising a high level of reb audioside AM (Reb AM) are described. These compositions are flavors with modifying properties, or FMPs. Using an FMP, certain flavor notes in a consumable product may be enhanced, while other flavor notes may be suppressed.
    Type: Grant
    Filed: May 17, 2020
    Date of Patent: July 14, 2026
    Assignee: PureCircle USA Inc.
    Inventors: Avetik Markosyan, Saravanan A/L Ramandach, Mohamad Afzaal Bin Hasim, Khairul Nizam Bin Nawi, Siew Yin Chow, Siddhartha Purkayastha
  • Patent number: 12622375
    Abstract: Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such plants to confer such desirable Reb M phenotypes to plant progeny.
    Type: Grant
    Filed: December 13, 2023
    Date of Patent: May 12, 2026
    Assignees: PureCircle USA, Inc., KeyGene N.V., The Coca-Cola Company
    Inventors: Avetik Markosyan, Seong Siang Ong, Runchun Jing, Tengfang Huang, Fayaz Khazi, Stephen Ezra Schauer, Indra Prakash, Alec Hayes
  • Patent number: 12604825
    Abstract: A stevia cultivar containing a high Rebaudioside M content, designated ‘18136109’, is disclosed. The invention relates to the plant parts of stevia cultivar ‘18136109’, to the plants of stevia ‘18136109’ and to methods for producing a stevia plant produced by crossing the cultivar ‘18136109’ with itself or another stevia variety, including methods using marker assisted breeding. The invention further relates to hybrid stevia seeds and plants produced by crossing the cultivar ‘18136109’ with another stevia cultivar. Twelve highly polymorphic SNPs loci and the corresponding genomic sequences used to identify plant variety ‘18136109’-derived plant materials are also disclosed.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: April 21, 2026
    Assignee: PureCircle USA Inc.
    Inventors: Avetik Markosyan, Runchun Jing, Seong Siang Ong, Yucheng Bu, Jianning Chen, Yeen Yee Wong, Chunhui Wang, Hongwei Liao
  • Publication number: 20260055130
    Abstract: Methods for purifying steviol glycosides, including Rebaudioside X, are provided herein. Sweetener and sweetened containing Rebaudioside X are also provided herein. Methods of improving the flavor and/or temporal profile of sweetenable compositions, such as beverages, are also provided.
    Type: Application
    Filed: September 24, 2025
    Publication date: February 26, 2026
    Inventor: Avetik MARKOSYAN
  • Publication number: 20260033524
    Abstract: A food or beverage product is provided comprising a steviol glycoside composition, said composition comprising 5-30 wt % rebaudioside M (reb M), 15-35 wt % rebaudioside AM (reb AM), and 10-25 wt % rebaudioside N2 (reb N2) based on the total amount of steviol glycosides in the product, wherein the steviol glycoside composition is present in an amount below its sweetness threshold. It is found that the food or beverage product has a modified or enhanced flavor compared to a food or beverage product not comprising the steviol glycoside composition.
    Type: Application
    Filed: July 28, 2023
    Publication date: February 5, 2026
    Inventors: Kasi SUNDARESAN, Maryam SAYEED, Avetik MARKOSYAN
  • Publication number: 20260009063
    Abstract: Methods of preparing highly purified steviol glycosides are described. The methods include utilizing enzyme preparations and recombinant microorganisms for converting various starting compositions to target steviol glycosides. The highly purified steviol glycosides are useful as non-caloric sweetener, flavor enhancer, sweetness enhancer, flavor stabilizer, flavoring with modifying properties (FMP), foaming suppressor and solubility enhancing agent in consumable products such as any food, beverages, pharmaceutical compositions, tobacco products, nutraceutical compositions, and oral hygiene compositions.
    Type: Application
    Filed: June 30, 2023
    Publication date: January 8, 2026
    Inventors: Avetik MARKOSYAN, Pei Chen KOH, Mohamad Afzaal BIN HASIM, Khairul NIZAM BIN NAWI, Saravanan A/L RAMANADACH, Kristina CHKHAN
  • Patent number: 12514274
    Abstract: A method for making a granulated Stevia sweetener is described. The resulting sweetener has a desirably high solubility level.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: January 6, 2026
    Assignee: PureCircle Sdn. Bhd.
    Inventors: Siddhartha Purkayastha, Avetik Markosyan
  • Patent number: 12479877
    Abstract: A method is described for purifying Rebaudioside X using a plurality of adsorbent columns packed with an adsorbent resin, passing a solution containing Rebaudioside X through the columns to adsorb Rebaudioside X onto the adsorbent resin, and eluting the Rebaudioside X from the adsorbent resin to result in purified Rebaudioside X.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: November 25, 2025
    Assignees: The Coca-Cola Company, PureCircle Sdn. Bhd.
    Inventors: Indra Prakash, Avetik Markosyan, Venkata Sai Prakash Chaturvedula, Mary Campbell, Rafael San Miguel, Siddhartha Purkayastha, Marquita Johnson
  • Publication number: 20250326782
    Abstract: Glucosylated chlorogenic acid (GCGA) compounds, particularly compounds selected from those having structural formulae (A), (B), (C), (D), (E), (F), salts thereof, and combinations thereof, and methods of preparing same are described. The GCGA compounds are useful in beverage products, food products, and home care products.
    Type: Application
    Filed: April 28, 2023
    Publication date: October 23, 2025
    Inventors: Avetik MARKOSYAN, Pei Chen KOH, Yeen Yee WONG, Siew Yin CHOW, Khairul NIZAM BIN NAWI
  • Patent number: 12441753
    Abstract: Methods for purifying steviol glycosides, including Rebaudioside X, are provided herein. Sweetener and sweetened containing Rebaudioside X are also provided herein. Methods of improving the flavor and/or temporal profile of sweetenable compositions, such as beverages, are also provided.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: October 14, 2025
    Assignees: PureCircle Sdn. Bhd., The Coca-Cola Company
    Inventor: Avetik Markosyan
  • Publication number: 20250295084
    Abstract: A stevia cultivar with super high Rebaudioside A content, designated ‘320032’, is disclosed. Another embodiment relates to the plant parts of stevia cultivar ‘320032’, to the plants of stevia ‘320032’ and to methods for producing a stevia plant produced by crossing the cultivar ‘320032’ with itself or another stevia variety, including methods using marker assisted breeding. Another embodiment further relates to hybrid stevia seeds and plants produced by crossing the cultivar ‘320032’ with another stevia cultivar. Twelve highly polymorphic SNPs loci and the corresponding genomic sequences used to identify plant variety ‘320032’-derived plant materials are also disclosed.
    Type: Application
    Filed: April 23, 2025
    Publication date: September 25, 2025
    Applicant: PureCircle USA Inc.
    Inventors: AVETIK MARKOSYAN, RUNCHUN JING, SEONG SIANG ONG, CHUNHUI WANG, YUCHENG BU, JIANNING CHEN, YEEN YEE WONG
  • Patent number: 12408689
    Abstract: Rebaudioside M compositions with improved aqueous solubility and methods for preparing the same are provided herein. The rebaudioside M compositions include (i) disordered crystalline compositions comprising rebaudioside M and rebaudioside D, (ii) spray-dried compositions comprising rebaudioside M, rebaudioside D and steviol glycoside mixtures and/or rebaudioside B and/or NSF-02, (iii) spray-dried compositions comprising rebaudioside M, rebaudioside D and at least one surfactant, polymer, saponin, carbohydrate, polyol, preservative or a combination thereof. Sweetened compositions, such a beverages, containing the rebaudioside M compositions with improved water solubility are also provided herein.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: September 9, 2025
    Assignees: The Coca-Cola Company, PureCircle Sdn Bhd
    Inventors: Indra Prakash, Gil Ma, Avetik Markosyan, Youlung Chen
  • Patent number: 12402645
    Abstract: The present invention provides a process for preparation of highly purified mogrosides mixture from low purity mogrosides mixture.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: September 2, 2025
    Assignee: PureCircle Sdn. Bhd.
    Inventor: Avetik Markosyan
  • Publication number: 20250268285
    Abstract: A Stevia extract made from leaves of the Stevia rebaudiana plant is described. The extract has desired levels of steviol glycosides and is useful in food, beverage, and other consumable products.
    Type: Application
    Filed: May 12, 2025
    Publication date: August 28, 2025
    Inventor: Avetik MARKOSYAN
  • Publication number: 20250263768
    Abstract: Methods of preparing highly purified steviol glycosides, particularly steviolmonoside, steviolmonoside A, steviolbioside, steviolbioside A, steviolbioside B, rubusoside, stevioside, stevioside A (rebaudioside KA), stevioside B, stevioside C, rebaudioside E, rebaudioside E2, rebaudioside E3, and rebaudioside AM are described. The methods include utilizing enzyme preparations and recombinant microorganisms for converting various staring compositions to target steviol glycosides. The highly purified rebaudiosides are useful as non-caloric sweetener, flavor enhancer, sweetness enhancer, and foaming suppressor in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.
    Type: Application
    Filed: April 9, 2025
    Publication date: August 21, 2025
    Inventors: Avetik MARKOSYAN, Saravanan A/L RAMANDACH, Mohamad Afzaal BIN HASIM, Khairul NIZAM BIN NAWI, Siew Yin CHOW
  • Patent number: 12378590
    Abstract: Methods of preparing highly purified steviol glycosides. The methods include utilizing enzyme preparations and recombinant microorganisms for converting various starting compositions to target steviol glycosides. The highly purified steviol glycosides are useful as non-caloric sweetener, flavor enhancer, sweetness enhancer, and foaming suppressor in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.
    Type: Grant
    Filed: February 15, 2020
    Date of Patent: August 5, 2025
    Assignee: PURECIRCLE USA INC.
    Inventors: Avetik Markosyan, Siew Yin Chow, Khairul Nizam Bin Nawi, Kristina Chkhan, Mohamad Afzaal Bin Hasim, Saravanan A/L Ramandach
  • Publication number: 20250228275
    Abstract: A taste and flavor profile modifying composition is described. The composition includes a blend of glucosylated steviol glycosides and residual steviol glycosides which can modify the intensity of a taste and/or flavor in a food or beverage product.
    Type: Application
    Filed: April 7, 2025
    Publication date: July 17, 2025
    Inventors: Siddhartha PURKAYASTHA, Avetik MARKOSYAN
  • Patent number: 12295391
    Abstract: A Stevia extract made from leaves of the Stevia rebaudiana plant is described. The extract has desired levels of steviol glycosides and is useful in food, beverage, and other consumable products.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: May 13, 2025
    Assignee: PURECIRCLE USA INC.
    Inventor: Avetik Markosyan
  • Patent number: 12284959
    Abstract: A stevia cultivar with super high Rebaudioside A content, designated ‘320032’, is disclosed. Another embodiment relates to the plant parts of stevia cultivar ‘320032’, to the plants of stevia ‘320032’ and to methods for producing a stevia plant produced by crossing the cultivar ‘320032’ with itself or another stevia variety, including methods using marker assisted breeding. Another embodiment further relates to hybrid stevia seeds and plants produced by crossing the cultivar ‘320032’ with another stevia cultivar. Twelve highly polymorphic SNPs loci and the corresponding genomic sequences used to identify plant variety ‘320032’-derived plant materials are also disclosed.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: April 29, 2025
    Assignee: PureCircle USA Inc.
    Inventors: Avetik Markosyan, Runchun Jing, Seong Siang Ong, Chunhui Wang, Yucheng Bu, Jianning Chen, Yeen Yee Wong