Abstract: Provided are methods for biological sample processing and analysis. A method can comprise providing a substrate configured to rotate. The substrate can comprise an array having immobilized thereto a biological analyte. A solution comprising a plurality of probes may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector can be configured to detect a signal from the at least one probe coupled to the biological analyte, thereby analyzing the biological analyte.

Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of probes may be directed, via centrifugal force, across the array during rotation of the substrate, to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via continuous rotational area scanning of the substrate.

Abstract: Provided are systems for biological sample processing and analysis. A system can comprise a substrate configured to rotate. The substrate can comprise an array configured to immobilize a biological analyte. A fluid flow unit comprising a fluid channel can be configured to dispense a solution comprising a plurality of probes. The solution may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector in optical communication with the array can be configured to detect one or more signals from the at least one probe coupled to the biological analyte.

Abstract: A method and a system for evaluating a content of a bin, the method may include: transmitting at a first point in time and by a first acoustic transceiver array, a first acoustic pulse; receiving by a second acoustic transceiver array an echo of the first acoustic pulse; and processing the echo of the first acoustic pulse to assist in a provision of a first estimate related to the content; wherein the second acoustic transceiver array differs from the first transceiver array; wherein a distance between the first and second acoustic transceiver array is at least ten times a distance between transducers of the second acoustic transceiver array.

Abstract: A method and a system for evaluating a content of a bin, the method may include (a) transmit multiple acoustic pulses by multiple acoustic transceiver arrays towards different areas of an upper surface of the content when the acoustic transceivers are positioned at different locations; wherein the multiple acoustic transceiver arrays are connected to a device that is moved according to a movement pattern between the different locations; receive by the multiple acoustic transceiver arrays multiple echoes of the multiple acoustic pulses; process by the multiple acoustic transceiver arrays the multiple echoes to provide multiple estimates of the different areas; associate with the multiple estimates of the different areas timing information indicative of a timing of the receiving of the multiple echoes to a computer; and obtain by an acoustic based location device, location information readings related to locations of the device at multiple points of time.

Abstract: A method and a system for evaluating a content of a bin, the method may include: transmitting by multiple acoustic transceiver arrays, a plurality of acoustics pulses in an at least partially overlapping manner towards an expected location of the content to generate an acoustic interference pattern that comprises multiple fringes; detecting by an acoustic transceiver array a first fringe of the acoustic interference pattern and providing a fringe detection signal; and processing the first fringe detection signal to assist in a provision of a first estimate related to the content. A distance between a pair of acoustic transceiver arrays is at least ten times a distance between transducers of a same acoustic transceiver array.

Abstract: A positioning system, includes a plurality of anchor stations each configured to transmit a radio frequency signal. A mobile station includes a radio frequency transceiver configured to transmit and receive a radio frequency signal from at least one of the plurality of anchor stations. A processing unit is configured to determine position information of the mobile unit based upon the transmitted and received radio frequency signal. Another positioning system uses a number of beacons ranging a number of mobile tags with ultra-wide band ranging, and communicating wirelessly with an application server.

Abstract: An ultrawide band two-way ranging based positioning system includes a number of active tags each having a position, and a number of beacons configured for location of a position of a tag of the plurality of active tags. The active tags and the beacons are synchronized continuously to a common time base.

Abstract: A method, non-transitory computer readable medium and a system that includes a confidence level module arranged to calculate, in response to detection signals, estimated upper surface points and to associate a non-binary confidence level with each estimated upper surface point; wherein the detection signals are generated by a receiver in response to an irradiation of at least a portion of the upper surface of the content with radiation pulses transmitted by a transmitter; and an estimator that is arranged to calculate an estimate of the upper surface based upon the estimated upper surface points and the non-binary confidence level associated with each estimated upper surface point.

Abstract: A method and a system for automatically mapping obstacles within a bin that stores content, the system may include: a location estimator that is arranged to calculate, in response to detection signals, an estimated shape of an upper surface of the content; wherein the detection signals are generated by a receiver in response to radiation signals reflected or scattered from multiple points within the bin; and an obstacle detector that is arranged to detect at least one obstacle point that belongs to an obstacle in response to (a) the estimated shape of the upper surface of the content, and (b) an expected shape attribute of the upper surface of the content.

Abstract: An indoor position system, includes a plurality of anchor stations each configured to transmit a radio frequency signal and an acoustic signal. A mobile station includes a radio frequency receiver configured to receive a radio frequency signal from at least one of the plurality of anchor stations and an acoustic receiver configured to receive an acoustic signal from at least one of the plurality of anchor stations. A processing unit is configured to determine position information of the mobile unit based upon the received radio frequency signal and acoustic signal.

Abstract: A method, non-transitory computer readable medium and a system that includes a fuzzy logic module arranged to apply a fuzzy logic algorithm for calculating, in response to received echoes that are received by a receiver, confidence levels of origins of received echoes; wherein the received echoes are reflected or scattered from the origins; and a volume calculator that is arranged to calculate a volume of the content in response to (a) estimated locations of the origins, and (b) the confidence levels of the origins.

Abstract: A method and a system for automatically mapping obstacles within a bin that stores content, the system may include a location estimator that is arranged to calculate, in response to detection signals, multiple estimates of shapes of the upper surface of the content at different time periods; wherein the detection signals are generated by a receiver in response to radiation signals reflected or scattered within the bin; and an obstacle detector that is arranged to detect an obstacle in response to relationships between the multiple estimates of shapes of the upper surface of the content.

Abstract: A system for measuring the height of bin contents includes transmitters for transmitting pulses of wave energy towards the upper surface of the contents and receivers for receiving echoes of the pulses and producing corresponding signals. The transmitters and receivers are distributed aerially above the contents. The system also includes a processing apparatus, for using the received signals to map the upper surface, that includes correlators that correlate pulse waveforms with the signals, and a beamformer. In one embodiment, the beamformer computes, from the signals considered as corresponding to echoes, of pulses from fewer synthetic transmitters, received at a synthetic receiver array, respective directions of arrival of the signals.

Abstract: A multi-beam scanning electron beam device (100) is described. The multi-bea scanning electron beam device having a column, includes a multi-beam emitter (110) for emitting a plurality of electron beams (12,13,14), at least one common electron beam optical element (130) having a common opening for at least two of the plurality of electron beams and being adapted for commonly influencing at least two of the plurality of electron beams, at least one individual electron beam optical element (140) for individually influencing the plurality of electron beams, a common objective lens assembly (150) for focusing the plurality of electrons beams having a common excitation for focusing at least two of the plurality of electron beams, and adapted for focusing the plurality of electron beams onto a specimen (20) for generation of a plurality of signal beams (121, 131,141), and a detection assembly (170) for individually detecting each signal beam on a corresponding detection element.

Abstract: A computer creates a recipe for a manufacturing tool based on design data. The computer obtains the design data, which includes basic elements and hierarchical levels corresponding to the basic elements. The computer selects one or more basic elements of interest and generates one or more sets of simple array cells corresponding to a level of interest. The computer uses the sets of simple array cells to identify periodical areas in level-of-interest coordinates to enable automated recipe creation. The periodical areas are identified with respect to one or more basic elements.

Abstract: An indoor position system, includes a plurality of anchor stations each configured to transmit a radio frequency signal and an acoustic signal. A mobile station includes a radio frequency receiver configured to receive a radio frequency signal from at least one of the plurality of anchor stations and an acoustic receiver configured to receive an acoustic signal from at least one of the plurality of anchor stations. A processing unit is configured to determine position information of the mobile unit based upon the received radio frequency signal and acoustic signal.

Abstract: A method and a system for evaluating a content of a bin, the method may include: transmitting by multiple acoustic transceiver arrays, a plurality of acoustics pulses in an at least partially overlapping manner towards an expected location of the content to generate an acoustic interference pattern that comprises multiple fringes; detecting by an acoustic transceiver array a first fringe of the acoustic interference pattern and providing a fringe detection signal; and processing the first fringe detection signal to assist in a provision of a first estimate related to the content. A distance between a pair of acoustic transceiver arrays is at least ten times a distance between transducers of a same acoustic transceiver array.

Abstract: A method and a system for evaluating a content of a bin, the method may include (a) transmit multiple acoustic pulses by multiple acoustic transceiver arrays towards different areas of an upper surface of the content when the acoustic transceivers are positioned at different locations; wherein the multiple acoustic transceiver arrays are connected to a device that is moved according to a movement pattern between the different locations; receive by the multiple acoustic transceiver arrays multiple echoes of the multiple acoustic pulses; process by the multiple acoustic transceiver arrays the multiple echoes to provide multiple estimates of the different areas; associate with the multiple estimates of the different areas timing information indicative of a timing of the receiving of the multiple echoes to a computer; and obtain by an acoustic based location device, location information readings related to locations of the device at multiple points of time

Abstract: A method and a system for evaluating a content of a bin, the method may include: transmitting at a first point in time and by a first acoustic transceiver array, a first acoustic pulse; receiving by a second acoustic transceiver array an echo of the first acoustic pulse; and processing the echo of the first acoustic pulse to assist in a provision of a first estimate related to the content; wherein the second acoustic transceiver array differs from the first transceiver array; wherein a distance between the first and second acoustic transceiver array is at least ten times a distance between transducers of the second acoustic transceiver array.