Abstract: A method of cooling a mammal with an implantable blood pump. The method includes measuring a temperature of an internal controller, the internal controller being in communication with the implantable blood pump. an alert is generated if the temperature of the internal controller exceeds a predetermined temperature threshold.

Abstract: A system for treating obstructive sleep apnea (OSA) is described. The system may include a locking device having a size and shape selected to couple to skin along a jaw of a patient. The locking device may be configured to receive at least one of a needle or an introducer for insertion into a tongue of the patient for lead placement of a lead for OSA treatment, and lock at least a portion of the at least one of the needle or introducer in place to reduce movement of the needle or introducer within the tongue.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.

Abstract: A sleep apnea and obesity comorbidity treatment system includes a transceiver and a control module. The control module is configured to: receive sensor data, where the sensor data is indicative of a glucose level of a patient and a ketones level of the patient, transmit the sensor data to a remote feedback device, receive feedback information from the remote feedback device based on the sensor data, and where the feedback information provides indications to the patient to maintain or alter a behavior of the patient based on the glucose level and the ketones level, and based on the feedback information, performing an operation to maintain or alter at least one of a diet or physical activity of the patient.

Abstract: A removable oral device is disclosed. The removable oral device comprises a mounting retainer configured to align with a set of teeth. An electrical stimulator is coupled to the mounting retainer. A single lead is employed that has a first and a second end and lacking a mechanical connection to the mounting retainer. A first and a second electrode are positioned along the single lead. The lead is disposed perpendicular to a longitudinal axis of a patient's tongue such that the first electrode is proximate a first hypoglossal nerve and the second electrode is proximate a second hypoglossal nerve.

Abstract: Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.

Abstract: A system for detecting strokes includes a sensor device configured to obtain physiological data from a patient, for example brain activity data. The sensor device can include electrodes configured to be disposed at the back of the patient's neck or base of the skull. The electrodes can detect electrical signals corresponding to brain activity in the P3, Pz, and/or P4 brain regions or other brain regions. A computing device communicatively coupled to the sensor device is configured to receive the physiological data and analyze it to indicate whether the patient has suffered a stroke.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.

Abstract: A system for treating obstructive sleep apnea (OSA) is described. The system may include a locking device having a size and shape selected to couple to skin along a jaw of a patient. The locking device may be configured to receive at least one of a needle or an introducer for insertion into a tongue of the patient for lead placement of a lead for OSA treatment, and lock at least a portion of the at least one of the needle or introducer in place to reduce movement of the needle or introducer within the tongue.

Abstract: A lead for delivering electrical stimulation therapy is described. The lead includes an elongated member defining a longitudinal axis, one or more electrodes disposed at a distal end of the elongated member, a plurality of collars located along the longitudinal axis, and one or more fixation members. At least one of the fixation members is a bow-like member having a first connection point to a first collar of the plurality of collars and a second connection point to a second collar of the plurality of collars. The distal end of the elongated member is configured for insertion in a tongue of a patient such that the one or more electrodes are implanted proximate to one or more motor points of a protrusor muscle within the tongue of the patient and the bow-like member of the one or more fixation members is implanted within tissue of the tongue.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.

Abstract: A system for treatment of obstructive sleep apnea (OSA) is described. The system includes an introducer needle having an elongated body. The introducer needle is configured to create an opening in a tongue of a patient for implantation of a lead for treating OSA. One or more electrically conductive areas are located on the elongated body. A medical device is configured to deliver a stimulation signal via the introducer needle through the one or more electrically conductive areas to the tongue of the patient to stimulate one or more motor points of a protrusor muscle within the tongue of the patient.

Abstract: This disclosure is directed to devices, systems, and techniques for monitoring a patient condition. In some examples, a medical device system includes processing circuitry configured to determine a plurality of pulse transit time (PTT) intervals, determine, based on an accelerometer signal, a posture of a patient from a plurality of postures corresponding to each PTT interval of the plurality of PTT intervals, classify each PTT interval of the plurality of PTT intervals based on the respective posture of the patient corresponding to the respective PTT interval, and monitor, based on the classified plurality of PTT intervals, a patient condition.

Abstract: An implantable neurostimulator (INS) and method of use, the INS including an electrical lead having formed thereon at least a pair of bi-polar electrodes, wherein the electrical lead is configured for placement of the pair of bi-polar electrodes proximate protrusor muscles of a patient, a pulse generator electrically connected to the electrical lead and configured to deliver electrical energy to the pair of bi-polar electrodes, the pulse generator having mounted therein a sensor and a control circuit, and the sensor is configured to generate signals representative of an orientation of the pulse generator and communicate the signals to the control circuit and the control circuit is configured to determine the orientation of the pulse generator and deliver electrical energy to the bi-polar electrodes when the determined orientation correlates to a pre-determined orientation.

Abstract: A system and method of diagnosing sleep apnea including an implantable device with a sensor, a telemetry circuit and a memory, an external programmer in communication with the telemetry circuit and configured to receive data collected by the sensor and stored in the memory. The system and method include operation of a server, including a processor, in communication with the external programmer and storing an application including instructions that when executed by the processor executes steps of receiving the data collected by the sensor from the external programmer, analyzing the received data collected by the sensor, and transmitting to a remote computer an assessment of the received sensor data, wherein the assessment includes an evaluation of sleep apnea for the patient.

Abstract: A medical device system and method are disclosed for treating obstructive sleep apnea. The system includes a pulse generator and a medical electrical lead including multiple electrodes carried by a distal portion of an elongated lead body. The method includes advancing the distal portion within protrusor muscle tissue below the oral cavity and delivering electrical stimulation pulses via the electrodes to sustain a protruded state throughout a delivery time period to sustain a protruded state of a patient's tongue throughout the therapy delivery time period. The therapy delivery time period may span multiple respiration cycles.

Abstract: A system and method of assessing therapy of an implantable neurostimulator (INS), the INS including a lead having at least one pair of bi-polar electrodes, and a pulse generator in electrical communication with the bi-polar electrodes, the pulse generator including a sensor, a memory, a control circuit, and a telemetry circuit. The system and method includes an external programmer in communication with the INS via the telemetry circuit, a server in communication with the external programmer and including thereon an application configured to receive sensor data from the INS from the external programmer and assess a quality of the sleep of a patient in which the INS is implanted based on the received sensor data, and a remote computer in communication with the server and configured to present an assessment of the quality of sleep of the patient.