Abstract: Described are systems, methods, and computer readable medium for a lottery reconciliation system. Exemplary embodiments provide systems, methods, and computer readable medium for reconciling online lottery game transactions. Exemplary embodiments also provide systems, methods, and computer readable medium for reconciling instant lottery game transactions. Exemplary embodiments also provide systems, methods, and computer readable medium for reconciling lottery game transaction at an interactive vending machine.

Abstract: Disclosed are pyrazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts and N-oxides thereof, wherein X1, X2, Z1, Z2, the ring system denoted by “a”, R1, A1A, L1B, A1B, L1A, L2, Q, L3, R3, A4A, L4B, A4B, L4A, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein disrupt the eIF4E/eiF4G interaction, and can be used to treat hyperproliferative disorder, a neurological disease or disorder, or autism.

Abstract: A system and a method for assembling a core engine and a fan case of a gas turbine engine. The system includes a core engine support that detachably supports the core engine. The core engine support includes at least one core engine alignment sensor. The system further includes a fan case support that detachably supports the fan case. The fan case support includes at least one fan case alignment sensor. The system further includes a computer-controllable unit configured to align the core engine support and the fan case support based on signals from the at least one core engine alignment sensor and the at least one fan case alignment sensor. The computer-controllable unit is further configured to guide a movement of at least one of the core engine support and the fan case support to couple the core engine with the fan case.

Abstract: The battery-powered backpack blower includes a back support assembly including a back plate configured to permit a user to mount the blower to the user's back, and a volute assembly including a first volute portion and a second volute portion. The backpack blower further includes a housing assembly including a battery assembly and a motor assembly therein, the housing assembly is provided intermediate to the back assembly and the volute assembly.

Abstract: The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Abstract: An electronic circuit includes a driver circuit having an output terminal that can be coupled to a load to drive the load. A control circuit is coupled to the driver circuit for controlling the driver circuit. A transistor is coupled in series between the driver circuit and the output terminal. The transistor has a first terminal coupled to the driver circuit and a second terminal coupled to the output terminal. A biasing circuit is coupled to a gate terminal of the transistor and configured to provide a constant voltage to the gate terminal to bias the transistor to a conducting state to reduce the susceptibility of the electronic circuit to electromagnetic interference. The biasing circuit includes a voltage regulator, a Zener diode, and a capacitor. The Zener diode and capacitor are coupled to the gate terminal and a reference terminal.

Abstract: The battery-powered backpack blower includes a back support assembly including a back plate configured to permit a user to mount the blower to the user's back, and a volute assembly including a first volute portion and a second volute portion. The backpack blower further includes a housing assembly including a battery assembly and a motor assembly therein, the housing assembly is provided intermediate to the back assembly and the volute assembly.

Abstract: A method of replacing a module in a modular gas turbine engine having a first fan module; a first propulsor module including an engine core and a gearbox; and a first fan case module having a fan case; includes the steps of: disassembling the gas turbine engine, replacing one of the fan module, propulsor module or fan case module with a replacement fan module, a replacement propulsor module or a replacement fan case module, the replacement module, having the same configuration as the first module; and reassembling the gas turbine engine using the replacement module.

Abstract: A gas turbine engine for an aircraft includes: an engine core having a turbine, a compressor, and a core shaft connecting the turbine to the compressor, wherein the engine core extends along a rotational axis, and has an engine core diameter perpendicular to the rotational axis; and a fan having a plurality of fan blades extending radially from the rotational axis, wherein the fan has a fan diameter perpendicular to the rotational axis, wherein a ratio of the engine core diameter to the fan diameter is between 1:1.7 and 1:2.2.

Abstract: A method of calibrating an engine core of a gas turbine engine, wherein the engine core includes a turbine, combustion equipment, a compressor, and a core shaft connecting the turbine to the compressor, the core shaft arranged to drive a propulsive fan of the gas turbine engine, the method including: providing a resistance load on the core shaft, the resistance load arranged to replicate the load of a propulsive fan; driving the engine core; measuring a performance parameter or the engine core; measuring a thrust generated by the engine core; and determining power rating data of the engine core, providing a correlation between the performance parameter and the thrust.

Abstract: A fan case for a gas turbine aircraft engine, the fan case formed of a wall extending in a loop around an axis (9?) and along the axis (9?), and having a case length along the axis (9?), and a case perimeter around the axis, wherein the fan case comprises two or more longitudinal segments configured to be assembled to form the wall, wherein each longitudinal segment includes a portion of the wall extending at least part of the length of the fan case and forming an incomplete portion of the perimeter of the fan case.

Abstract: A method of upgrading a modular gas turbine engine, which includes: a first fan module with a fan having plurality of fan blades; a first engine core module including an engine core and a gearbox providing drive to the fan; and a first fan case module with a fan case arranged to enclose the fan blades, the method including: disassembling the gas turbine engine, replacing one of the first fan module, first engine core module or first fan case module with a replacement fan module, a replacement engine core module or a replacement fan case module; and reassembling the gas turbine engine using the replacement module, which is compatible with the others of the first fan module, first engine core module or first fan case module; and the replacement module designed to different parameters to one of the first fan module, first engine core module or first fan case module.

Abstract: Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “a”, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

Abstract: Textured fabrics have raised projections separated by depressed areas. The raised projections have heights of 0.3 to 8 mm above the level of the surrounding depressed areas. The raised projections have a pitch of 0.25 to 10 mm. The raised projections are locked into the fabric by the presence of a flexible, crosslinked polymer. The fabrics are water-resistant and breathable. The raised projections and the depressed areas create channels through which water can flow, maintaining the air permeability of the textured fabric during rainstorms. The textured fabric may be part of an outerwear rain jacket.

Abstract: A tooling and a method for removing or mounting a fan blade from or to a fan disc of a ducted fan aeroengine are provided. The tooling comprises a cover adapted to be arranged on an inner wall of an air intake of the aeroengine and a boot adapted to be mounted on a leading edge tip of the blade and adapted to slide on the cover during removing or mounting the fan blade from or to the fan disc.

Abstract: The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured, humanized antibodies, antibody fragments, etc., that specifically bind a Sortilin protein, e.g., human Sortilin or mammalian Sortilin, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.

Abstract: Disclosed are pyrazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure (I) and pharmaceutically acceptable salts and/V-oxides thereof, wherein X1, X2, Z1, Z2, the ring system denoted by “a”, R1, A1A, L1B, A1B, L1A, L2, Q, L3, R3, A4A, L4B, A4B, L4A, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein disrupt the eIF4E/eiF4G interaction, and can be used to treat hyperproliferative disorder, a neurological disease or disorder, or autism.

Abstract: A system for mounting a gas turbine engine to a pylon on a wing of an aircraft. At least one temporary forward link, being length-adjustable, and at least one temporary rearward link, being length-adjustable, are provided. These are for temporarily attaching the gas turbine engine to the pylon. The temporary forward link and the temporary rearward link each comprise a respective winch operable to adjust pay out of a respective tension member thereby to provide length adjustment. The temporary forward link and the temporary rearward link maintain a positional relationship between the gas turbine engine and the pylon in the absence of adjustment of the lengths of the temporary forward link and the temporary rearward link. Adjustment of the length of the temporary links brings engine mounts into alignment with pylon mounts for service attachment of the gas turbine engine to the pylon.

Abstract: A system for mounting a gas turbine engine to a pylon on a wing of an aircraft. A temporary forward link, being length-adjustable, and at least one temporary rearward link, being length-adjustable, are provided. These are for temporarily attaching the gas turbine engine to the pylon. The temporary forward link and the temporary rearward link are each adapted to resist tension and compression, to maintain a positional relationship between the gas turbine engine and the pylon in the absence of adjustment of the lengths of the temporary forward link and the temporary rearward link. Adjustment of the length of the temporary links brings engine mounts into alignment with pylon mounts for service attachment of the gas turbine engine to the pylon.