Abstract: Coupling mechanisms for engaging and releasing a tool attachment such as a socket from a drive element include an engaging element and an actuating element. The actuating element can include a collar or other manually-accessible part, and various features allow for a relatively small outside diameter for the collar or other part. These features include configuring the actuating element to contact the engaging element within the drive element, placing the biasing elements within the drive element, and forming guides for parts of the actuating element within the drive element. Also, the engaging element can move along a direction that is oriented at an oblique angle to the longitudinal axis of the drive element, in whole or in part. The engaging element can have a first part that moves obliquely in the drive element and a second part that moves radially in the drive element to engage the tool attachment.

Abstract: A universal joint includes first and second parts interconnected by a coupling element, and a coupling mechanism for detachably engaging tool attachments such as sockets. The disclosed coupling mechanisms include an engaging element and an actuating element. The engaging element can include a pin, and the pin can be oriented either obliquely or longitudinally in the drive stud of the universal joint. The actuating element can include a collar and a central portion that crosses the central longitudinal axis of the drive stud. The central portion can be offset along the longitudinal axis toward the coupling element, and the actuating element can be configured to extend into an aperture formed by the coupling element and the second part of the universal joint.

Abstract: Coupling mechanisms for engaging and releasing a tool attachment such as a socket from a drive element include an engaging element and an actuating element. The actuating element can include a collar or other manually-accessible part, and various features allow for a relatively small outside diameter for the collar or other part. These features include configuring the actuating element to contact the engaging element within the drive element, placing the biasing elements within the drive element, and forming guides for parts of the actuating element within the drive element Also, the engaging element can move along a direction that is oriented at an oblique angle to the longitudinal axis of the drive element, in whole or in part. The engaging element can have a first part that moves obliquely in the drive element and a second part that moves radially in the drive element to engage the tool attachment.

Abstract: 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl(DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described.

Abstract: The condensation-free and bacteria-free pan system provides hygienic cover for a food preparation area. The system includes at least one pan having a top cover sheet, a heating element, a layer of thermal insulation and a bottom pan sheet. The top cover sheet is formed from a corrosion resistant material and is adapted for catching contaminants falling from overhead. The layer of thermal insulation is sandwiched between the top cover sheet and the heating element, and the bottom pan sheet is formed from a thermally conductive, corrosion resistant material, the bottom pan sheet having a lower wall and at least one sidewall. The top cover sheet, the layer of thermal insulation and the heating element are disposed above the bottom pan sheet to form a multilayer pan.

Abstract: Coupling mechanisms for engaging and releasing a tool attachment such as a socket from a drive element include an engaging element and an actuating element. The actuating element can include a collar or other manually-accessible part, and various features allow for a relatively small outside diameter for the collar or other part. These features include configuring the actuating element to contact the engaging element within the drive element, placing the biasing elements within the drive element, and forming guides for parts of the actuating element within the drive element Also, the engaging element can move along a direction that is oriented at an oblique angle to the longitudinal axis of the drive element, in whole or in part. The engaging element can have a first part that moves obliquely in the drive element and a second part that moves radially in the drive element to engage the tool attachment.

Abstract: A universal joint includes first and second parts interconnected by a coupling element, and a coupling mechanism for detachably engaging tool attachments such as sockets. The disclosed coupling mechanisms include an engaging element and an actuating element. The engaging element can include a pin, and the pin can be oriented either obliquely or longitudinally in the drive stud of the universal joint. The actuating element can include a collar and a central portion that crosses the central longitudinal axis of the drive stud. The central portion can be offset along the longitudinal axis toward the coupling element, and the actuating element can be configured to extend into an aperture formed by the coupling element and the second part of the universal joint.

Abstract: Tools for detachably engaging a tool attachment are described that include a drive element and a mechanism for altering engagement forces between the tool attachment and the drive element. The mechanism includes a locking element and an actuating element coupled to the locking element.

Abstract: A ratchet wrench has a drive-stud element with a drive stud at a first end and a drive recess at a second end. The drive-stud element is coupled with a one-way drive transmitting wheel to rotate in unison therewith about an axis. The wrench can have a centering element that resists movement of the one-way drive transmitting wheel in at least one direction away from the axis. The drive-stud element and the one-way drive transmitting wheel can be separately formed. A method is also disclosed for operating a ratchet wrench with a drive-stud element with a drive stud at a first end and a drive recess at a second end.

Abstract: 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl (DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described.

Abstract: A tool of the type having a drive stud for receiving and releasing a tool attachment includes an opening in the drive stud and a locking pin movably mounted in the opening. The opening defines first and second ends, and the first end of the opening is located at a portion of the drive stud constructed for insertion into the tool attachment. An actuating member is movably positioned on the drive stud, and the actuating member defines a sliding surface that engages the pin. A first spring biases the sliding surface toward the pin, and a second, weaker spring biases the pin toward the sliding surface. The first spring reacts against a ring that is disposed between the spring and a shoulder formed on the tool. The shoulder extends away from the longitudinal axis of the drive stud by a lesser distance than the spring or the ring.

Abstract: A tool of the type having a drive stud for receiving and releasing a tool attachment includes an opening in the drive stud and a locking pin movably mounted in the opening. The opening defines first and second ends, and the first end of the opening is located at a portion of the drive stud constructed for insertion into the tool attachment. An actuating member is movably positioned on the drive stud, and the actuating member defines a sliding surface that engages the pin. A first spring biases the sliding surface toward the pin, and a second, weaker spring biases the pin toward the sliding surface. The first spring reacts against a ring that is disposed between the spring and a shoulder formed on the tool. The shoulder extends away from the longitudinal axis of the drive stud by a lesser distance than the spring or the ring.

Abstract: The invention provides enantiomers of ajoene and derivatives of Z(?)-ajoene. The derivative of Z(?)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.

Abstract: A remote tracking and communication device comprising a housing which encloses a processor, a memory, a position locator, a first transmitter, and a second transmitter. Each of the latter components are electronically coupled to the processor. Both the first and second transmitters are adapted to send and receive wireless voice and data signals in a digital format. The device further comprises a first battery, which is removably affixed to the housing and electronically coupled to each component within the housing, a speaker and a microphone electronically coupled to the first transmitter, and a button electronically coupled to the processor. When pressed, the button is adapted to activate voice communications with a call center using the first transmitter.

Abstract: The invention relates to systems and methods for assessing blood flow in single or multiple vessels and segments, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for effect, for assessing risk factors, for evaluating intracranial pressure and for analyzing the results in a defined manner. The invention enables direct monitoring of therapies, substances and devices on blood vessels, especially those of the cerebral vasculature. Relevant blood flow parameters include mean flow velocity, systolic acceleration, and pulsatility index. Measurement and analysis of these parameters, and others, provides details regarding the vascular health of individual and multiple vessels and a global analysis of an individual's overall vascular health.

Abstract: The invention provides enantiomers of ajoene and derivtives of Z(?)-ajoene. The derivative of Z(?)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.

Abstract: The present invention relates generally to systems and methods for assessing blood flow in blood vessels, for assessing vascular health, for conducting clinical trials, for screening therapeutic interventions for adverse effects, and for assessing the effects of risk factors, therapies and substances, including therapeutic substances, on blood vessels, especially cerebral blood vessels, all achieved by measuring various parameters of blood flow in one or more vessels and analyzing the results in a defined matter. The relevant parameters of blood flow include mean flow velocity, systolic acceleration, and pulsatility index. By measuring and analyzing these parameters, one can ascertain the vascular health of a particular vessel, multiple vessels and an individual. Such measurements can also determine whether a substance has an effect, either deleterious or advantageous, on vascular health. In one of many embodiments, the present invention further provides an expert system for achieving the above.

Abstract: A system for refrigeration of products includes a case having a compartment defining a space configured to receive the products. A first heat exchanger is configured to cool a fluid communicating with the space to cool the objects. A second heat exchanger is configured to receive a heat supply from an air source to warm the fluid. At least one coolant supply line and at least one coolant discharge line are configured to direct the fluid in communication with the space.

Abstract: A temperature controlled service case for storage and display of chilled or frozen products, including at least one compartment for product storage, at least one access opening providing entrance to the compartment, at least one shelf within the compartment for holding product, and refrigeration operatively associated with the compartment for maintaining a selected temperature therein. The refrigeration includes at least one cooling coil above the shelf with a cooling medium flowing therethrough, and cooling within the shelf with a cooling medium flowing therethrough. Coolant supply is also provided for supplying cooling medium to the cooling coil and shelf.

Abstract: A temperature controlled service case for storage and display of chilled or frozen products, including at least one compartment for product storage, at least one access opening providing entrance to the compartment, at least one shelf within the compartment for holding product, and refrigeration operatively associated with the compartment for maintaining a selected temperature therein. The refrigeration includes at least one cooling coil above the shelf with a cooling medium flowing therethrough, and cooling within the shelf with a cooling medium flowing therethrough. Coolant supply is also provided for supplying cooling medium to the cooling coil and shelf with separate coolant supply and discharge lines from the coolant supply to the cooling coil and shelf. In accordance with a further embodiment, the shelf is divided into separate sections. In accordance with a still further embodiment, means are provided to warm the coolant for at least one of said cooling coil and shelf.