Patents by Inventor B. Narasimhulu Naidu

B. Narasimhulu Naidu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20240374598
    Abstract: Compounds and pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.
    Type: Application
    Filed: July 12, 2024
    Publication date: November 14, 2024
    Inventors: Michael S. Bowsher, Eric P. Gillis, Christiana Iwuagwu, B. Narasimhulu Naidu, Kyle E. Parcella, Manoj Patel, Kevin M. Peese
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20240182473
    Abstract: The invention relates to compounds of Formula (I), (Ia), (II) or (IIa), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: November 14, 2023
    Publication date: June 6, 2024
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John F. MILLER, B. Narasimhulu NAIDU, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • Compounds Useful in HIV Treatment
    Publication number: 20240182510
    Abstract: The invention relates to compounds of Formula (I), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: February 21, 2022
    Publication date: June 6, 2024
    Applicant: ViiV Healthcare Company
    Inventor: B. Narasimhulu NAIDU
  • COMPOUNDS WITH HIV MATURATION INHIBITORY ACTIVITY
    Publication number: 20230192758
    Abstract: The present invention relates to compound of Formula I or a pharmaceutically acceptable salt thereof wherein R1 is where the squiggly line indicates the point of attachment to the rest of the molecule; R2 is F or where the squiggly line indicates the point of attachment to the rest of the molecule; R3 is H or CH3; Z is O or is absent; and R4 is —OC1-3alkyl, C1-30alkyl, or —N(CH3)2.
    Type: Application
    Filed: January 12, 2023
    Publication date: June 22, 2023
    Inventors: John F. KADOW, B. Narasimhulu Naidu
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20230013823
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
    Type: Application
    Filed: October 2, 2020
    Publication date: January 19, 2023
    Inventors: Michael S. BOWSHER, Eric P. GILLIS, B. Narasimhulu NAIDU, Kyle E PARCELLA, Manoj PATEL
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20220411425
    Abstract: The invention relates to a compound having the structure: or a pharmaceutically acceptable salt thereof, along with pharmaceutical compositions and therapeutic methods thereof.
    Type: Application
    Filed: June 1, 2021
    Publication date: December 29, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John F. MILLER, B. Narasimhulu NAIDU, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20220409619
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
    Type: Application
    Filed: September 29, 2020
    Publication date: December 29, 2022
    Inventors: B. Narasimhulu NAIDU, Manoj PATEL
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20220389007
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
    Type: Application
    Filed: September 29, 2020
    Publication date: December 8, 2022
    Inventors: Michael S. BOWSHER, Eric P. GILLIS, Christiana IWUAGWU, B Narasimhulu NAIDU, Kyle E. PARCELLA, Manoj PATEL
  • 4-oxo-3,4-dihydroquinazoline compounds as inhibitors of human immunodeficiency virus replication
    Patent number: 11505543
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: November 22, 2022
    Assignee: VIIV HEALTHCARE UK (NO.5) LIMITED
    Inventors: Makonen Belema, John A. Bender, David B. Frennesson, Eric P. Gillis, Christiana Iwuagwu, John F. Kadow, B. Narasimhulu Naidu, Kyle E. Parcella, Kevin M. Peese, Ramkumar Rajamani, Mark G. Saulnier, Alan Xiangdong Wang, Manoj Patel, Michael S. Bowsher
  • Compounds Useful in HIV Therapy
    Publication number: 20220117993
    Abstract: The invention relates to compounds of the Formula: salts thereof, pharmaceutical compositions thereof, combinations thereof, as well as therapeutic methods of treatment and prevention.
    Type: Application
    Filed: August 8, 2019
    Publication date: April 21, 2022
    Applicants: GlaxoSmithKline Intellectual Property (No. 2) Limited, VIIV Healthcare Company
    Inventors: John Franklin MILLER, David TEMELKOFF, Emile Johann VELTHUISEN, Martha Alicia DE LA ROSA, Lita SUWANDI, B. Narasimhulu NAIDU
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20210393633
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
    Type: Application
    Filed: October 22, 2019
    Publication date: December 23, 2021
    Inventors: Eric P. GILLIS, Kyle E. PARCELLA, Manoj PATEL, B. Narasimhulu NAIDU
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20210379071
    Abstract: Compounds and pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.
    Type: Application
    Filed: November 4, 2019
    Publication date: December 9, 2021
    Inventors: Michael S. BOWSHER, Eric P. GILLIS, Christiana IWUAGWU, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Manoj PATEL, Kevin M. PEESE
  • COMPOUNDS WITH HIV MATURATION INHIBITORY ACTIVITY
    Publication number: 20210347813
    Abstract: The present invention relates to compound of Formula I or a pharmaceutically acceptable salt thereof wherein R1 is where the squiggly line indicates the point of attachment to the rest of the molecule; R2 is F or where the squiggly line indicates the point of attachment to the rest of the molecule; R3 is H or CH3; Z is O or is absent; and R4 is —OC1-3alkyl, C1-30alkyl, or —N(CH3)2.
    Type: Application
    Filed: April 22, 2019
    Publication date: November 11, 2021
    Inventors: John F. KADOW, B. Narasimhulu NAIDU
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 10954252
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: March 23, 2021
    Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
    Inventors: Suresh Babu, Makonen Belema, John A. Bender, Christiana Iwuagwu, John F. Kadow, Selvakumar Kumaravel, Pulicharla Nagalakshmi, B. Narasimhulu Naidu, Manoj Patel, Kevin M. Peese, Ramkumar Rajamani, Mark Saulnier, Alan Xiangdong Wang
  • 4-OXO-3,4-DIHYDROQUINAZOLINE COMPOUNDS AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20210024503
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
    Type: Application
    Filed: April 11, 2019
    Publication date: January 28, 2021
    Inventors: Makonen BELEMA, John A. BENDER, David B. FRENNESSON, Eric P. GILLIS, Christiana IWUAGWU, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Kevin M. PEESE, Ramkumar RAJAMANI, Mark G. SAULNIER, Alan Xiangdong WANG, Manoj PATEL, Michael S. BOWSHER
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20200325127
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: May 9, 2017
    Publication date: October 15, 2020
    Inventors: John F. KADOW, B Narasimhulu NAIDU, Tao WANG, Zhiwei YIN, Zhongxing ZHANG
  • 5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
    Patent number: 10577353
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: March 3, 2020
    Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
    Inventors: John F. Kadow, B. Narasimhulu Naidu, Tao Wang, Zhiwei Yin, Zhongxing Zhang
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20200055839
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: January 2, 2018
    Publication date: February 20, 2020
    Inventors: Makonen BELEMA, Michael S. BOWSHER, Jeffrey A. DESKUS, Kyle J. EASTMAN, Eric P. GILLIS, David B. FRENNESSON, Christiana IWUAGWU, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Kevin M. PEESE, Mark G. SAULNIER, Prasanna SIVAPRAKASAM
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20200016136
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: January 2, 2018
    Publication date: January 16, 2020
    Inventors: Michael S. BOWSHER, Jeffrey DESKUS, Kyle J. EASTMAN, Eric P. GILLIS, David B. FRENNESSON, Christiana IWUAGWU, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Kevin M. PEESE, Mark G. SAULNIER, Prasanna SIVAPRAKASAM
  • Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
    Patent number: 10407410
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: September 10, 2019
    Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
    Inventors: John F. Kadow, B. Narasimhulu Naidu, Manoj Patel, Michael A. Walker, Tao Wang, Zhiwei Yin, Zhongxing Zhang, Zhizhen Barbara Zheng