Patents by Inventor B. Narasimhulu Naidu

B. Narasimhulu Naidu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV Integrase Inhibitors
    Publication number: 20120309745
    Abstract: The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: December 7, 2011
    Publication date: December 6, 2012
    Inventors: Kevin Peese, B. Narasimhulu Naidu, Manoj Patel, Chen Li, Michael A. Walker
  • HIV Integrase Inhibitors
    Publication number: 20120309698
    Abstract: The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: December 6, 2011
    Publication date: December 6, 2012
    Inventors: Yasutsugu Ueda, Timothy P. Connolly, Barry L. Johnson, Chen Li, B. Narasimhulu Naidu, Manoj Patel, Kevin Peese, Margaret E. Sorenson, Michael A. Walker, Michael S. Bowsher, Rongti Li
  • HIV integrase inhibitors
    Patent number: 8129398
    Abstract: The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: March 6, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: Francis Beaulieu, Carl Ouellet, B. Narasimhulu Naidu, Manoj Patel, Yasutsugu Ueda, Timothy P. Connolly, Jonathan R. Weiss, Michael A. Walker, Nicholas A. Meanwell, Kevin M. Peese, Margaret E. Sorenson, Chen Li
  • HIV integrase inhibitors
    Patent number: 8039458
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: October 18, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Yasutsugu Ueda, John D. Matiskella, Michael A. Walker, Jacques Banville, Francis Beaulieu, Carl Ouellet, Serge Plamondon
  • HIV Integrase Inhibitors
    Publication number: 20110245241
    Abstract: The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: October 8, 2010
    Publication date: October 6, 2011
    Inventors: B. Narasimhulu Naidu, Kevin Peese, Ira B. Dicker, Chen Li, Manoj Patel, Nicholas A. Meanwell, Michael A. Walker
  • HIV integrase inhibitors
    Patent number: 7902182
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: March 8, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson, Yasutsugu Ueda, John D. Matiskella, Michael A. Walker
  • HIV integrase inhibitors
    Patent number: 7897593
    Abstract: The invention encompasses series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: March 1, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson
  • HIV integrase inhibitors
    Patent number: 7897592
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: March 1, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventor: B. Narasimhulu Naidu
  • HIV integrase inhibitors
    Patent number: 7893055
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: February 22, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Walker, Chen Li, Katharine A. Grant-Young, John D. Matiskella, B. Narasimhulu Naidu, Jacques Banville, Francis Beaulieu, Carl Ouellet, Annapurna Pendri, Roger Remillard, Yasutsugu Ueda, Ting T. Yin
  • HIV integrase inhibitors
    Patent number: 7763630
    Abstract: The invention encompasses a series pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: July 27, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson, Manoj Patel
  • HIV Integrase Inhibitors
    Publication number: 20090253677
    Abstract: The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: March 18, 2009
    Publication date: October 8, 2009
    Inventors: Francis Beaulieu, Carl Ouellet, B. Narasimhulu Naidu, Manoj Patel, Yasutsugu Ueda, Timothy P. Connolly, Jonathan R. Weiss, Michael A. Walker, Nicholas A. Meanwell, Kevin M. Peese, Margaret E. Sorenson
  • N-[[4-fluoro-2-(5-methy-1H-1,2,4-triazol-1-yl)phenyl]methyl]-4-,6,7,9-tetrahydro-3-hydroxy-9,9-dimethyl-4-oxo-pyrimido[2,1-c][1,4]oxazine-2-carboxamide as an HIV integrase inhibitor
    Patent number: 7511037
    Abstract: The invention encompasses a series of bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: March 31, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Jacques Banville, Francis Beaulieu, Timothy P. Connolly, Mark R. Krystal, John D. Matiskella, Carl Ouellet, Serge Plamondon, Roger Remillard, Margaret E. Sorenson, Yasutsugu Ueda, Michael A. Walker
  • N-[4-Fluorophenyl)methyl]-4,6,7,9-tetrahydro-3-hydroxy-9,9-dimethyl-4-oxo-pyrimido[2,1-c][1,4]oxazine-2-carboxamide as an HIV integrase inhibitor
    Patent number: 7491819
    Abstract: The invention encompasses a series of bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: February 17, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson, Dawn DiGiugno
  • HIV Integrase Inhibitors
    Publication number: 20080306051
    Abstract: The invention encompasses a series pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: June 3, 2008
    Publication date: December 11, 2008
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson, Manoj Patel
  • HIV integrase inhibitors: cyclic pyrimidinone compounds
    Patent number: 7419969
    Abstract: The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: September 2, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Timothy P. Connolly, Yasutsugu Ueda
  • HIV Integrase Inhibitors
    Publication number: 20080004265
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: June 26, 2007
    Publication date: January 3, 2008
    Inventors: Michael A. Walker, Chen Li, Katharine A. Grant-Young, John D. Matiskella, B. Narasimhulu Naidu, Jacques Banville, Francis Beaulieu, Carl Ouellet, Annapurna Pendri, Roger Remillard, Yasutsugu Ueda, Ting T. Yin
  • HIV Integrase Inhibitors
    Publication number: 20070281917
    Abstract: The invention encompasses series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: May 29, 2007
    Publication date: December 6, 2007
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson
  • HIV integrase inhibitors: cyclic pyrimidinone compounds
    Patent number: 7273859
    Abstract: The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: September 25, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventor: B. Narasimhulu Naidu
  • HIV INTEGRASE INHIBITORS
    Publication number: 20070129379
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: November 17, 2006
    Publication date: June 7, 2007
    Inventors: B. Narasimhulu Naidu, Yasutsugu Ueda, Timothy Connolly
  • HIV integrase inhibitors
    Publication number: 20070112190
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Application
    Filed: November 14, 2006
    Publication date: May 17, 2007
    Inventor: B. Narasimhulu Naidu