Patents by Inventor B. Narasimhulu Naidu

B. Narasimhulu Naidu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic heterocycles as HIV integrase inhibitors
    Patent number: 7192948
    Abstract: The invention encompasses a series cyclic bicyclic heterocyclic compounds of Formula I which are inhibitors of HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: March 20, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jacques Banville, Gilles Bouthillier, B. Narasimhulu Naidu, Roger Remillard, Michael A. Walker
  • Bicyclic heterocycles as HIV integrase inhibitors
    Patent number: 7176196
    Abstract: The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
    Type: Grant
    Filed: May 11, 2005
    Date of Patent: February 13, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Jacques Banville, Francis Beaulieu, Timothy P. Connolly, Mark R. Krystal, John D. Matiskella, Carl Ouellet, Serge Plamondon, Roger Remillard, Margaret E. Sorenson, Yasutsugu Ueda, Michael A. Walker
  • Bicyclic heterocycles as HIV integrase inhibitors
    Patent number: 7173022
    Abstract: The invention encompasses a series cyclic bicyclic heterocyclic compounds of Formula I which are inhibitors of HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: February 6, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Jacques Banville, John D. Matiskella, Serge Plamondon, Yasutsugu Ueda
  • Bicyclic heterocycles as HIV integrase inhibitors
    Patent number: 7157447
    Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: January 2, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Jacques Banville, Francis Beaulieu, Timothy P. Connolly, Mark R. Krystal, John D. Matiskella, Carl Ouellet, Serge Plamondon, Roger Remillard, Margaret E. Sorenson, Yasutsugu Ueda, Michael A. Walker
  • HIV integrase inhibitors
    Patent number: 7115601
    Abstract: Compounds of the present disclosure are spirocycle-substituted pyrimidinecarboxamides. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating HIV infection and AIDS.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: October 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Margaret E. Sorenson
  • HIV integrase inhibitors
    Patent number: 7109186
    Abstract: The present invention describes novel compounds of Formula I which inhibit HIV integrase.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: September 19, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Walker, Zhuping Ma, B. Narasimhulu Naidu, Margaret E. Sorenson, Annapurna Pendri, Jacques Banville, Serge Plamondon, Roger Remillard
  • HIV integrase inhibitors
    Patent number: 7037908
    Abstract: The present invention relates to a series of pyrimidine compounds of Formula I which inhibit HIV integrase and to pharmaceutical compositions and methods of treatment for AIDS or ARC using these compounds
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: May 2, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: B. Narasimhulu Naidu, Michael A. Walker, Margaret E. Sorenson
  • O-derivatized nocathiacin derivatives
    Patent number: 7022667
    Abstract: The present invention provides compounds of formula I having potent antibiotic activity, including activity towards Gram-positive bacteria and mycobacteria.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: April 4, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Thomas W. Hudyma, Xiaofan Zheng, B. Narasimhulu Naidu, Margaret E. Sorenson, Alicia Regueiro-Ren, Timothy P. Connolly, John D. Matiskella, Oak K. Kim, Yunhui Zhang, Dane M. Springer, Jason Goodrich, Yasutsugu Ueda, Joanne J. Bronson
  • Topoisomerase I selective cytotoxic sugar derivatives of indolopyrrolocarbazoles
    Patent number: 6855698
    Abstract: The present invention relates to fluoro sugar and other sugar derivatives of indolopyrrolocarbazoles, their salts and hydrates, which exhibit selective topoisomerase I (topo I) activity, are useful in inhibiting the proliferation of tumor cells and exhibit an antitumor effect, as well as processes for their preparation.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: February 15, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Edward H. Ruediger, Mark G. Saulnier, Francis Beaulieu, Carol Bachand, Neelakantan Balusubramanian, Byron Hepler Long, David B. Frennesson, Kurt Zimmermann, B. Narasimhulu Naidu, Karen Stoffan, Denis Robert St. Laurent
  • HIV integrase inhibitors
    Publication number: 20040229892
    Abstract: The present invention relates to a series of pyrimidine compounds of Formula I which inhibit HIV integrase and to pharmaceutical compositions and methods of treatment for AIDS or ARC using these compounds.
    Type: Application
    Filed: April 15, 2004
    Publication date: November 18, 2004
    Inventors: B. Narasimhulu Naidu, Michael A. Walker, Margaret E. Sorenson
  • HIV integrase inhibitors
    Publication number: 20040110804
    Abstract: The present invention describes novel compounds of Formula I which inhibit HIV integrase. The invention also describes compositions and treatments of AIDS or ARC by using these compounds.
    Type: Application
    Filed: July 9, 2003
    Publication date: June 10, 2004
    Inventors: Michael A. Walker, Zhuping Ma, B. Narasimhulu Naidu, Margaret E. Sorenson, Annapurna Pendri, Jacques Banville, Serge Plamondon, Roger Remillard
  • O-derivatized nocathiacin derivatives
    Publication number: 20040018963
    Abstract: The present invention provides compounds of formula I 1
    Type: Application
    Filed: July 3, 2002
    Publication date: January 29, 2004
    Inventors: Thomas W. Hudyma, Xiaofan Zheng, B. Narasimhulu Naidu, Margaret E. Sorenson, Alicia Regueiro-Ren, Timothy P. Connolly, John D. Matiskella, Oak K. Kim, Yunhui Zhang, Dane M. Springer, Jason Goodrich, Yasutsugu Ueda, Joanne J. Bronson
  • Topoisomerase I selective cytotoxic sugar derivatives of indolopyrrolocarbazoles
    Publication number: 20030083271
    Abstract: The present invention relates to fluoro sugar and other sugar derivatives of indolopyrrolocarbazoles, their salts and hydrates, which exhibit selective topoisomerase I (topo I) activity, are useful in inhibiting the proliferation of tumor cells and exhibit an antitumor effect, as well as processes for their preparation.
    Type: Application
    Filed: March 22, 2002
    Publication date: May 1, 2003
    Inventors: Edward H. Ruediger, Mark G. Saulnier, Francis Beaulieu, Carol Bachand, Neelakantan Balusubramanian, Byron Hepler Long, David B. Frennesson, Kurt Zimmermann, B. Narasimhulu Naidu, Karen Stoffan, Denis Robert St. Laurent
  • Water soluble thiazolyl peptide derivatives
    Publication number: 20020065219
    Abstract: Novel thiazolyl peptide compounds useful for the treatment of serious bacterial infections, and pharmaceutical compositions thereof are provided.
    Type: Application
    Filed: August 13, 2001
    Publication date: May 30, 2002
    Inventors: B. Narasimhulu Naidu, Wenying Li, Kin S. Lam, Margaret E. Sorenson, John A. Wichtowski, Timothy P. Connolly, Yasutsugu Ueda, Joanne J. Bronson, Yunhui Zhang, Oak K. Kim