Abstract: This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based on identifying the risk of progressive multifocal leukoencephalopathy PML using a genetic test.

Abstract: A Stirling cycle machine with a liquid fuel/gaseous fuel burner. The burner may include a preheater to capture the thermal energy of the exhaust. The burner directs the preheated air to each burner head, where it enters a prechamber. Each burner head includes a fuel nozzle that directs liquid or gaseous fuel into the prechamber. The prechamber is fluidically connected to a combustion chamber via a prechamber nozzle that has a smaller opening than the prechamber. The burner head ignites the fuel air mixture in the prechamber with an ignitor located above or within the prechamber. The flame is initially lit as a diffusion flame in the prechamber. The flame is pushed out of the prechamber into the combustion chamber by an increased air flow rate. The liquid fuel from the nozzle now evaporates in the prechamber and forms a prevaporized flame in the combustion chamber.

Abstract: This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based on identifying the risk of progressive multifocal leukoencephalopathy PML using a genetic test.

Abstract: This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based on identifying the risk of progressive multifocal leukoencephalopathy PML using a genetic test.

Abstract: An ultrasonic instrument includes a body, an actuation assembly, a shaft assembly, and an end effector. The actuation assembly includes an activation member that is operable to move in a first direction to select a mode of operation. The shaft assembly extends distally from the body and includes an acoustic waveguide. The end effector includes an ultrasonic blade that is in acoustic communication with the acoustic waveguide. The activation member is operable to move in a second direction to activate the end effector in a mode of operation selected by movement of the activation member in the first direction.

Abstract: A system for performing shear-assisted extrusion can include a front fixed endstock and a rear fixed endstock. The system can include a front movable headstock and a rear movable headstock. The system can include a die tool connected to the front fixed endstock. The die tool can include a face configured to engage and plasticize a face of feedstock material. The die tool can define an opening to receive plasticized feedstock material therethrough. The system can include a front spindle supported by the front movable headstock. The front spindle can be rotatable to rotate the feedstock material with respect to the front movable headstock. The system can include a rear spindle connected to the rear movable headstock, the rear spindle rotatable with respect to the rear movable headstock and the die tool.

Abstract: Systems and methods for measuring a temperature at a location within a patient's body such as at an in vivo location proximate to a site of intravenous fluid administration, are disclosed. In some embodiments, an insertable device includes an insertion tube member having a tip configured to be inserted into a blood vessel (or other body lumen) of a patient, and a temperature sensor operatively coupled to the insertion tube proximate the tip and configured to measure a temperature within the blood vessel during administration of a fluid through the insertion tube. The device may also include a controller operable to receive one or more signals from the temperature sensor indicative of the temperature within the blood vessel proximate the tip of the insertion tube.

Abstract: Clamp assemblies and associated methods are disclosed. According to one aspect, a clamp assembly may comprise a shell, a tensioning mechanism, and a retainer. The shell includes a pair of segments sized to be positioned over a joint connection, with the pair of segments being moveable between an open position and a contracted position. The tensioning mechanism is operable to tighten the pair of segments and includes a threaded shaft extending through a segment opening defined in a first segment of the pair of segments. The retainer is coupled with the first segment and includes a first cantilevered flange configured to engage the threaded shaft to retain the threaded shaft in the segment opening when the shell is in the open position.

Abstract: A medicine administration and tracking system includes a delivery device configured to deliver a plurality of doses of medicine over a plurality of days and a computing device configured to receive dose information for each dose. The computing device includes a software application operable to cause the computing device to retrieve the dose information for all doses within a pre-determined period of days, categorize each dose within the pre-determined period of days into one of a plurality of time blocks throughout a 24-hour timeframe, determine a time of interest based on a time block of the plurality of time blocks having the least amount of doses categorized therein, and select a physiological parameter reading from a plurality of physiological parameter readings as a physiological parameter reading of interest based on a proximity of a time of the physiological parameter reading to the determined time of interest.

Abstract: An ostomy device includes a proximal side configured for attachment to a user, a distal side opposite to the proximal side, and a leakage detection sensor having electrically conductive circuitry supported on a support layer. The leakage detection sensor is configured to detect ostomy effluent by detecting a change in resistance in the electrically conductive circuitry. The ostomy device may be an ostomy appliance or an ostomy accessory.

Abstract: The present invention relates to a fruit or vegetable shaped fan for dispersing airborne eye irritants that are released during cutting fruits or vegetables. The fan includes a base that is wedge-shaped, an air inflow collimator that is fruit or vegetable shaped having an open front end, an internal frame that is configured to provide minimal abatement to airflow through the air inflow collimator, a motor mount that secures a motor, a fan blade that attaches to the motor, and a grill that attaches to the open front end of the air inflow collimator. The fan is configured to disperse airborne eye irritants away from a user's eyes. Airborne eye irritants are released when certain fruits and vegetables are chopped or otherwise cut. Such fruits and vegetables that can release airborne eye irritants when cut include onions, peppers, and certain other fruits and vegetables.

Abstract: A method for operating an industrial automation system may involve receiving, via a first module of a plurality of modules in a control system, an indication that an error between a measurement associated with a target variable that corresponds with at least a portion of the industrial automation system and a modeled value for the target variable. The method may then involve determining, via the first module, whether the error is within a first range of values and retraining a model used to generate the modeled value for the target variable based on a portion of a plurality of sets of data points acquired via a plurality of sensors disposed in the industrial automation system in response to the error being within the first range of values.

Abstract: An ostomy device includes a proximal side configured for attachment to a user, a distal side opposite to the proximal side, and a leakage detection sensor having electrically conductive circuitry supported on a support layer. The leakage detection sensor is configured to detect ostomy effluent by detecting a change in resistance in the electrically conductive circuitry. The ostomy device may be an ostomy appliance or an ostomy accessory.

Abstract: An ultrasonic instrument includes a body, an actuation assembly, a shaft assembly, and an end effector. The actuation assembly includes an activation member that is operable to move in a first direction to select a mode of operation. The shaft assembly extends distally from the body and includes an acoustic waveguide. The end effector includes an ultrasonic blade that is in acoustic communication with the acoustic waveguide. The activation member is operable to move in a second direction to activate the end effector in a mode of operation selected by movement of the activation member in the first direction.

Abstract: A mobile phone may include a housing, a battery at least partially within the housing, and a circuit board assembly at least partially within the housing and positioned along a side of the battery. The circuit board assembly may include a first circuit board defining a first hole, a second circuit board defining a second hole, a wall structure between the first circuit board and the second circuit board and attached to an inner surface of the first circuit board and an inner surface of the second circuit board, and a fastener assembly configured to retain the first circuit board to the second circuit board.

Abstract: The present disclosure relates to a bead clamp ring for covering a bead clamp of a tire building machine during a tire building process, comprising an annular body formed of a flexible material that includes a central body portion, a proximal end body portion, and a distal end body portion. The proximal end body portion includes a securing to secure the bead clamp ring to the drum. The distal end body portion includes a bead lug to engage the bead clamp. The bead lug includes an annular recess, which includes a proximal recess portion communicated with the open recess end and an enlarged distal recess portion defining the closed recess end. The enlarged distal recess portion extends radially below the proximal recess portion and has a greater radial depth than the proximal recess portion. The enlarged distal recess portion is located distally of a mid-point of the bead lug length.