Patents by Inventor Barry Hart

Barry Hart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rho-kinase inhibitors
    Publication number: 20040014755
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: January 10, 2003
    Publication date: January 22, 2004
    Inventors: Dhanapalan Nagarathnam, Uday Khire, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Chunguang Wang, Barry Hart, Olaf Weber, Mark Lynch, Lei Zhang, Lei Wang
  • Process for preparing quinazoline Rho-kinase inhibitiors and intermediates thereof
    Publication number: 20030220357
    Abstract: A process for the preparation of various quinazoline compounds which are useful as Rho-Kinase inhibitors, and thus having utility in the treatment of hypertension and other indications.
    Type: Application
    Filed: September 24, 2002
    Publication date: November 27, 2003
    Inventors: Donald Bankston, Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • Rho-kinase inhibitors
    Publication number: 20030125344
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: March 22, 2002
    Publication date: July 3, 2003
    Applicant: BAYER CORPORATION
    Inventors: Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of PDE7B-mediated diseases and conditions
    Publication number: 20030119829
    Abstract: The invention relates to 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7B (PDE7B). Diseases and conditions mediated by PDE7B include osteoporosis, osteopenia and asthma.
    Type: Application
    Filed: April 29, 2002
    Publication date: June 26, 2003
    Inventors: Andreas Stolle, Donald E. Bierer, Yuanwei Chen, Dongping Fan Can, Barry Hart, Mary Katherine Monahan, William J. Scott