Patents by Inventor Bayard R. Huck

Bayard R. Huck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL BICYCLIC UREA COMPOUNDS
    Publication number: 20120190654
    Abstract: The invention provides novel substituted azaheterocyclic compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
    Type: Application
    Filed: July 28, 2010
    Publication date: July 26, 2012
    Applicant: MERCK PATENT GMBH
    Inventors: Xiaoling Chen, Srinivasa R. Karra, Bayard R. Huck, Ruoxi Lan, Amanda E. Sutton, Andreas Goutopoulos, Brian L. Hodous, Reinaldo Jones
  • Novel Amino Azaheterocyclic Carboxamides
    Publication number: 20120046269
    Abstract: The invention provides novel substituted amino azaheterocyclic carboxamide compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
    Type: Application
    Filed: February 4, 2010
    Publication date: February 23, 2012
    Applicant: Merck Patent GmbH
    Inventors: Amanda E. Sutton, Ruoxi Lan, Thomas E. Richardson, David Perrey, Harold George Vandeveer, Bayard R. Huck, Srinivasa R. Karra, Xiaoling Chen, Lesley Liu-Bujalski, Andreas Goutopoulos, Frank Steiber, Brian L. Hodous, Hui Qiu, Reinaldo C. Jones, Brian H. Heasley
  • Tricyclic Azaindoles
    Publication number: 20120022060
    Abstract: Disclosed are dipyridyl-pyrrole derivative compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.
    Type: Application
    Filed: December 3, 2009
    Publication date: January 26, 2012
    Applicant: MERCK PATENT GMBH
    Inventors: Bayard R. Huck, Amanda E. Sutton, Benny C. Askew, JR., Christopher Charles Victor Jones, Garry R. Smith, Nadia Brugger
  • C-Ring Modified Tricyclic Benzonaphthiridinone Protein Kinase Inhibitors and Use Thereof
    Publication number: 20110312951
    Abstract: Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.
    Type: Application
    Filed: December 2, 2009
    Publication date: December 22, 2011
    Applicant: MERCK PATENT GMBH
    Inventors: Yufang Xiao, Bayard R. Huck, Amanda E. Sutton, Thomas E. Richardson, Srinivasa R. Karra
  • NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS
    Publication number: 20110269758
    Abstract: Naphthyridinone derivative compounds that inhibit Aurora kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed Aurora kinases such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.
    Type: Application
    Filed: June 29, 2009
    Publication date: November 3, 2011
    Applicant: MERCK PATENT GMBH
    Inventors: Yufang Xiao, Bayard R. Huck, Amanda E. Sutton, Xiaoling Chen, Srinivasa R. Karra, Andreas Goutopoulos
  • PROTEIN KINASE INHIBITORS AND USE THEREOF
    Publication number: 20110053906
    Abstract: Disclosed are benzonaphthyridinyl derivative compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to kinase signal transduction inhibition, regulation or modulation.
    Type: Application
    Filed: February 25, 2009
    Publication date: March 3, 2011
    Applicant: MERCK PATENT GMBH
    Inventors: Bayard R. Huck, Xiaoling Chen, Lizbeth Celeste Deselm, Christopher Charles Victor Jones, Srinivasa R. Karra, Yufang Xiao, Andreas Goutopoulos, Amanda E. Sutton
  • Oligomers and polymers of di-substituted cyclic imino carboxylic acids
    Patent number: 7304165
    Abstract: Disclosed are cyclic imino oligomers and polymers comprised of subunits of the formula: Also disclosed are combinatorial libraries and arrays of the cyclic imino compounds.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: December 4, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Bayard R. Huck
  • Oligomers and polymers of di-substituted cyclic imino carboxylic acids
    Publication number: 20040152133
    Abstract: Disclosed are cyclic imino oligomers and polymers comprised of subunits of the formula: 1
    Type: Application
    Filed: January 21, 2004
    Publication date: August 5, 2004
    Inventors: Samuel H. Gellman, Bayard R. Huck
  • Oligomers and polymers of cyclic imino carboxylic acids
    Patent number: 6727368
    Abstract: Disclosed are cyclic imino oligomers and polymers comprised of subunits of the formula: Also disclosed are combinatorial libraries and arrays of the cyclic imino compounds.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: April 27, 2004
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Bayard R. Huck, Michele R. Richards
  • Oligomers and polymers of di-substituted cyclic imino carboxylic acids
    Patent number: 6710186
    Abstract: Disclosed are cyclic imino oligomers and polymers comprised of subunits of the formula: Also disclosed are combinatorial libraries and arrays of the cyclic imino compounds.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: March 23, 2004
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Bayard R. Huck
  • Oligomers and polymers of di-substituted cyclic imino carboxylic acids
    Publication number: 20020032334
    Abstract: Disclosed are cyclic imino oligomers and polymers comprised of subunits of the formula: 1
    Type: Application
    Filed: June 18, 2001
    Publication date: March 14, 2002
    Inventors: Samuel H. Gellman, Bayard R. Huck