Abstract: Provided are organometallic compounds comprising an at least two-dentate ligand comprising at least one 5-membered or 6-membered carbocyclic or heterocyclic ring. Further provided are organometallic compounds containing a platinum atom as the central metal atom. Also described are their various uses including as emitters in devices such as organic light emitting diodes and related electronic devices. Also provided are formulations comprising these organometallic compounds containing a platinum atom as the central metal atom. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these organometallic compounds.

Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and a balloon catheter assembly comprising an elongated balloon catheter shaft extending from the handle portion. The balloon catheter shaft includes a proximal end portion coupled to the handle portion and a distal end portion. The balloon catheter assembly further includes a balloon coupled to the distal end portion and configured to mount a prosthetic heart valve in a radially compressed state. A protective cover encapsulates the balloon, the cover defining a cavity shaped to accommodate the balloon.

Abstract: The present disclosure generally relate to spin-orbit torque (SOT) devices. The SOT devices each comprise a non-magnetic layer, a free layer disposed in contact with the non-magnetic layer, and a bismuth antimony (BiSb) layer disposed over the free layer. The non-magnetic layer has a thickness of about 0.5 nm to about 2 nm. The BiSb layer has a thickness of about 5 nm to about 10 nm. The BiSb layer and the free layer have collective thickness between about 5 nm to about 20 nm. By reducing the thickness of the non-magnetic layer and BiSb layer, a read gap of each SOT device is reduced while enabling large inverse spin Hall angles and high signal-to-noise ratios.

Abstract: A system for determining a distance between a receiver and a transmitter are disclosed herein. The transmitter includes a first antenna array having a first spatial orientation and is configured to transmit a signal. The receiver includes a second antenna array and an orientation sensor to determine a second spatial orientation of the second antenna array and is configured to receive the signal. A logic circuit is configured compare the first spatial orientation to the second spatial orientation to determine a relative orientation of the second antenna array; determine an angle of arrival of the signal; identify, based on the relative orientation of the second antenna array and the angle of arrival of the signal, a received signal strength compensation value; and calculate a distance between the transmitter and the receiver based on a measured received signal strength of the signal and the identified compensation value.

Abstract: The disclosure relates to methods for therapeutically targeting circulating tumor cells during hemodialysis, comprising: connecting a patient's bloodstream to a flow electroporator device, the device comprising: an array of polymeric channels, where the opposing sidewalls of each channel are lined with discontinuous sections of electrodes, interspersed by non-conductive polymer sections to generate sequential electric fields by constant direct current voltages; sequential electric fields with independently regulated intensity, duration, and polarity to induce lysis of circulating tumor cells and deliver chemotherapeutic agents to reduce the viability of circulating tumor cells; and polymeric tubing inlet and outlet for seamless integration into the bloodline tubing of any hemodialysis machine

Abstract: A panel assembly for use in a vehicle includes a first face sheet, a second face sheet, and a core layer disposed between the first and second face sheets. The core layer is defined by a base material along a first section of the panel assembly, and the core layer is defined by a honeycomb structure along a second section of the panel assembly. The first section and the second section are discrete, and the first section that includes the base material extends along a perimeter of the panel assembly.

Abstract: A device for crimping a radially expandable and collapsible prosthetic valve comprises a crimping loop having a first end portion, a second end portion, and a loop portion extending between the first and second end portions and defining an opening configured to receive the prosthetic valve. The crimping loop is movable between a first state in which the opening has a first diameter and a second state in which the opening has a second diameter smaller than the first diameter such that when the prosthetic valve is positioned within the loop portion, movement of the crimping loop from the first state to the second state is effective to reduce a diameter of the prosthetic valve. A method for crimping a prosthetic valve comprises reducing a diameter of an opening of a crimping loop, thereby radially compressing an at least partially expanded prosthetic valve disposed within the opening.

Abstract: A clip system is configured to secure an insulation blanket to a frame. The clip system includes a first clamp member including an adjustment arm and a first engagement arm, and a second clamp member including a sleeve and a second engagement arm. The sleeve is configured to adjustably retain the adjustment arm to allow the first clamp member and the second clamp member to be moveably adjusted. The first engagement arm and the second engagement arm are configured to securely clamp portions of the insulation blanket and the frame therebetween.

Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.

Abstract: An Alternate Wetting and Drying (AWD) method/system for irrigating a field using a pump comprising an outlet supplying water to the field and an inlet connected to a water source is disclosed. The method/system comprises a sensor placed at a location in the field for sensing a water depth below a surface of the field and transmitting the water depth to a controller located remotely from the sensing location using a wireless connection. The controller enables the pump when the sensed water depth is below a threshold depth and disables the pump when the sensed water depth is above a threshold depth.

Abstract: A clip system is configured to secure an insulation blanket to a frame. The clip system includes a first clamp member including an adjustment arm and a first engagement arm, and a second clamp member including a sleeve and a second engagement arm. The sleeve is configured to adjustably retain the adjustment arm to allow the first clamp member and the second clamp member to be moveably adjusted. The first engagement arm and the second engagement arm are configured to securely clamp portions of the insulation blanket and the frame therebetween.

Abstract: A system for determining a distance between a receiver and a transmitter are disclosed herein. The transmitter includes a first antenna array having a first spatial orientation and is configured to transmit a signal. The receiver includes a second antenna array and an orientation sensor to determine a second spatial orientation of the second antenna array and is configured to receive the signal. A logic circuit is configured compare the first spatial orientation to the second spatial orientation to determine a relative orientation of the second antenna array; determine an angle of arrival of the signal; identify, based on the relative orientation of the second antenna array and the angle of arrival of the signal, a received signal strength compensation value; and calculate a distance between the transmitter and the receiver based on a measured received signal strength of the signal and the identified compensation value.

Abstract: A rotating control device can include a bearing housing, an inner mandrel rotatably supported in the bearing housing, and a barrier having upper and lower portions, the upper portion being secured against rotation relative to the inner mandrel, the lower portion being secured against rotation relative to the bearing housing, the lower portion including annular recesses, the recesses being progressively deeper in a radially outward direction. Another barrier can include upper and lower portions, the lower portion including multiple annular walls, an upper surface of each wall being inclined downward in a radially outward direction. Another barrier can include upper and lower portions, the upper and lower portions having annular walls, the upper portion walls being interdigitated with the lower portion walls, and the upper and lower portion walls being circumferentially discontinuous, whereby gaps are formed between circumferential ends of the upper and lower portion walls.

Abstract: Devices and methods for crimping a prosthetic heart valve onto a delivery device are described. In some embodiments, valves are crimped over an inflatable balloon and between proximal and distal shoulders mounted on a shaft inside the balloon. Crimping methods can include multiple compression steps with the valve located in different axial positions relative to the crimping jaws at each different step. In some methods, the valve may extend partially outside of the crimping jaws during certain crimping steps, such that the crimping force is only applied to the part of the valve that is inside the jaws. Exemplary crimping devices can include two or more adjacent sets of jaws that close down to different inner diameters, such that different parts of a valve get compressed to different outer diameters at the same time during a single crimping step.

Abstract: A radio frequency (RF) device includes a spatial orientation sensor and logic circuit configured to determine spatial orientation of the RF device relative to a reference position or relative to a RF transmitter. In particular, the RF device determines a distance between the RF receiver and the RF transmitter based on a received signal strength of the signal and a determined spatial orientation of the RF device, by determining an orientation compensation value from a stored orientation compensation profile and determining a resulting compensated received signal strength. The RF device is thereby able to determine distance in an orientationally-invariant manner.

Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.

Abstract: The present disclosure relates to compositions of phytonutrients and methods of treating obesity by administering these compositions to subjects in need thereof. The compositions described herein are rationally designed compositions of phytonutrients that interfere with fat cell differentiation, a process commonly known as “adipogenesis”, to prevent weight gain and improve glycemic control. The phytonutrients are rationally combined based on their complementary effects on the expression level of six adipogenic biomarker proteins. Exemplary compositions can include one or more of berberine, luteolin, resveratrol, fisetin, quercetin, fucoidan, epigallocatechin gallate (EGCG), hesperidin, or curcumin.

Abstract: The present disclosure relates to compositions of phytonutrients and methods of treating diabetes by administering these compositions to subjects in need thereof. The compositions described herein are rationally designed compositions of phytonutrients that promote insulin sensitivity and have weight-loss potential. The compositions include formulation of rationally combined phytonutrients for diabetes treatment and management. Using nanofluidic proteomics, phytonutrients were classified as insulin sensitizing or anti-adipogenic based on their ability to enhance insulin-stimulated Akt2 phosphorylation and glucose uptake or inhibit adipogenesis, respectively. In some embodiments, the formulation includes a synergistic amount of insulin-sensitizing phytonutrients cinnamaldehyde and curcumin.

Abstract: Provided are organometallic compounds. Also provided are formulations comprising these organometallic compounds. Further provided are OLEDs and related consumer products that utilize these organometallic compounds.

Abstract: The present disclosure generally relates to systems, devices, and methods for providing control of fluids from a subject, which may be utilized with an introducer system. Such fluids may comprise blood and may be produced during medical operation upon the subject. An expandable sheath may be provided that is configured to cover a portion of an introducer sheath body between the surface of the subject and a housing of the introducer sheath to retain fluid from the subject within the expandable sheath.