Abstract: The invention relates to a rail vehicle (1) comprising a first passenger car and a powerpack (2) having a longitudinal axis, the powerpack (2) and the passenger car being coupled together. The powerpack (2) comprises at least one fuel cell (20) and at least one fuel tank (21) having a fuel tank valve (33). The powerpack (2) is mounted on at least one bogie. The rail vehicle (1) comprises at least one driven bogie which can be supplied with electrical energy from the fuel cell (20).

Abstract: The present invention relates to a blocking device (4) for a damper drive, wherein the blocking device (4) can be transferred by activation from an inoperative state into an alternative activated state. The blocking device (4) comprises a movably mounted blocking element (41) which, in a blocking position, blocks an output member (13) in a safety position. The blocking device (4) further comprises a drive element (42) which, when the blocking device (4) is activated, moves the blocking element (41) into the blocking position. The blocking device further comprises an activating element (43) which, when a blocking temperature has been exceeded, activates the blocking device (4) by an irreversible change in shape. Also disclosed are a damper drive with a blocking device, a fire protection device and a method for operating a fire protection device.

Abstract: The present invention discloses a method of manufacturing 4-chloro-7H-pyrrolo[2,3-d]pyrimidine comprising the steps: a) Preparing ethyl 2-cyano-4,4-dimethoxybutanoate by coupling ethyl 2-cyanoacetate and 2-bromo-1,1-dimethoxyethane; b) Preparing 6-amino-5-(2,2-dimethoxyethyl)pyrimidin-4-ol by adding formamidine to ethyl 2-cyano-4,4-dimethoxybutanoate; c) Converting 6-amino-5-(2,2-dimethoxyethyl)pyrimidin-4-ol to 7H-pyrrolo[2,3-d]pyrimidin-4-ol; and d) Converting the 7H-pyrrolo[2,3-d]pyrimidin-4-ol to 4-chloro-7H-pyrrolo[2,3-d]pyrimidine. The method offers increased yield, less by-products and a decrease in waste compared to methods known as being state of the art.

Abstract: The present invention discloses a method of manufacturing 4-chloro-7H-pyrrolo[2,3-d]pyrimidine comprising the steps: a) Preparing ethyl 2-cyano-4,4-dimethoxybutanoate by coupling ethyl 2-cyanoacetate and 2-bromo-1,1-dimethoxyethane; b) Preparing 6-amino-5-(2,2-dimethoxyethyl)pyrimidin-4-ol by adding formamidine to ethyl 2-cyano-4,4-dimethoxybutanoate; c) Converting 6-amino-5-(2,2-dimethoxyethyl)pyrimidin-4-ol to 7H-pyrrolo[2,3-d]pyrimidin-4-ol; and d) Converting the 7H-pyrrolo[2,3-d]pyrimidin-4-ol to 4-chloro-7H-pyrrolo[2,3-d]pyrimidine. The method offers increased yield, less by-products and a decrease in waste compared to methods known as being state of the art.

Abstract: A butterfly valve comprises a seat ring (1), a centered valve disc (3) and a valve axis (16). The seat ring (1) and the valve disc (3) are constructed to co-operate as first and second elements of a seal for sealing a volume in which the valve axis (16) is located from internal volume of the valve. The seal is substantially a radial-force-type seal with respect to the valve axis (16). The torque for opening or closing the valve is not more than 160 Nm. The invention relates further to an actuator for a butterfly valve comprising either a voltage detection and/or a temperature and/or humidity controller and/or a safety subsystem to prevent fire in the case of fault conditions. The invention relates further to a hand crank detection system for a butterfly valve, a position indicator for a butterfly valve and an adapter between a butterfly valve and its actuator.

Abstract: The present invention relates to a blocking device (4) for a damper drive, wherein the blocking device (4) can be transferred by activation from an inoperative state into an alternative activated state. The blocking device (4) comprises a movably mounted blocking element (41) which, in a blocking position, blocks an output member (13) in a safety position. The blocking device (4) further comprises a drive element (42) which, when the blocking device (4) is activated, moves the blocking element (41) into the blocking position. The blocking device further comprises an activating element (43) which, when a blocking temperature has been exceeded, activates the blocking device (4) by an irreversible change in shape. Also disclosed are a damper drive with a blocking device, a fire protection device and a method for operating a fire protection device.

Abstract: An actuator (1M, 1S) with a motor (12) and a motor controller (11) is configurable to operate as a master or a slave to another actuator which is coupled mechanically for driving a common load. For the case where the actuator (1M) is set as the master, the motor controller (11) receives on an input terminal (Y3) an external position control signal (pC), generates a motor control signal (sC) for controlling the motor (12) based on the position control signal (pC), and supplies the motor control signal (sC) to an output terminal (U5) for controlling a slave. For the case where the actuator (1S) is set as the slave, the motor controller (11) controls the motor (12) by supplying to the motor (12) the motor control signal (sC) received from the master. Controlling the actuators with a master improves workload balancing and reduces damages to transmission mechanics of the actuators.

Abstract: This device has a drive output element for the actuation of a rotatable body which is separate or separable from the device, and it has a housing part in which the drive output element is rotatably mounted. The drive output element has a coupling part which is designed for rotational positive locking and which is designed to be mounted on a corresponding coupling connector of the shaft of the rotatable body. The device is characterized in that a quick-action fastener arrangement is provided for the detachable connection of the coupling part to the coupling connector. Further, the quick-action fastener arrangement can have manually actuable elements for enabling the quick-action fastener arrangement to be closed without tools.

Abstract: The present invention relates to a novel process for preparing opiates or salts thereof. More particularly, the present invention relates to oxidizing the starting material in a continuous flow reactor, followed by either an isolation of the intermediate, or a direct reduction reaction.

Abstract: An actuator (1M, 1S) with a motor (12) and a motor controller (11) is configurable to operate as a master or a slave to another actuator which is coupled mechanically for driving a common load. For the case where the actuator (1M) is set as the master, the motor controller (11) receives on an input terminal (Y3) an external position control signal (pC), generates a motor control signal (sC) for controlling the motor (12) based on the position control signal (pC), and supplies the motor control signal (sC) to an output terminal (U5) for controlling a slave. For the case where the actuator (1S) is set as the slave, the motor controller (11) controls the motor (12) by supplying to the motor (12) the motor control signal (sC) received from the master. Controlling the actuators with a master improves workload balancing and reduces damages to transmission mechanics of the actuators.

Abstract: An actuator is described with a prestressed reduction gear, which acts via a drive organ, particularly in the form of a drive segment, of a linear drive or a drive spindle upon an actuator for regulating a gas or fluid flow, particularly in the fields of heating ventilation, air-conditioning and fire and smoke protection. Actuating movement is limited by end stops. At least one inner end stop on the housing side limits the rotational freedom of an end wheel, which is in a positive fit with the drive organ, up to more than a full rotation. In a prestressed reduction gear, a switching device g can comprise two spur gears which have identical diameter and can be driven in the opposite direction for changing the M direction of movement of the drive organ, each of which have a pinion which can be displaced in the axial direction. The pinions are in each axial position in a positive fit with the drive organ.

Abstract: The present invention relates to a novel process for preparing opiates or salts thereof. More particularly, the present invention relates to oxidizing the starting material in a continuous flow reactor, followed by either an isolation of the intermediate, or a direct reduction reaction.

Abstract: A process for the preparation of a compound of formula (Ib): including contacting a compound of formula (Ia): with toluene and HCl gas to provide the compound of formula (Ib).

Abstract: Amorolfine base, which is a compound of formula (I): is improvedly prepared by: (i) contacting a compound of formula (II): with a Friedel-Crafts catalyst; and (ii) adding one equivalent of 2-halogeno-2-methylbutane, wherein the reaction mixture obtained in step (i) is cooled to a temperature from ?40° to ?60° C. prior to step (ii) and the Friedel-Craft catalyst is selected from the group consisting of gallium chloride, antimony pentafluoride, molybdenum pentachloride, indium chloride, antimony pentachloride.

Abstract: A process for the preparation of a compound of formula (Ib): including contacting a compound of formula (Ia): with toluene and HCl gas to provide the compound of formula (Ib).

Abstract: A process for the preparation of a compound of formula (Ia): includes: (i) contacting a compound of formula (III): with a compound of formula (IV): in the presence of a palladium catalyst, methanol and hydrogen gas, the step (i) preferably being conducted under basic conditions with acetic acid being added to the medium of reaction once the consumption of the hydrogen gas has ceased.

Abstract: The invention relates to a drive system (A) for a fire protection flap (8) arranged in a ventilation duct (9). Said drive system (A) comprises at least one drive element (1), an energy supply element (2) for supplying energy to the drive element (1) and a mechanical load-torque lock (3) for absorbing a torque acting on the fire protection flap (8). The drive element (1) is made essentially of plastic. A thermal protection element (4) is at least arranged on the side of the drive element (1) which faces the ventilation duct (9).

Abstract: Amorolfine base, which is a compound of formula (I): is improvedly prepared by: (i) contacting a compound of formula (II): with a Friedel-Crafts catalyst; and (ii) adding one equivalent of 2-halogeno-2-methylbutane, wherein the reaction mixture obtained in step (i) is cooled to a temperature from ?40° to ?60° C. prior to step (ii) and the Friedel-Craft catalyst is selected from the group consisting of gallium chloride, antimony pentafluoride, molybdenum pentachloride, indium chloride, antimony pentachloride.

Abstract: The invention relates to an actuator (16) with a prestressed reduction gear (10), which acts via a drive organ (12), particularly in the form of a drive segment, of a linear drive or a drive spindle upon an actuator for regulating a gas or fluid flow, particularly in the fields of heating ventilation, air-conditioning and fire and smoke protection. The actuating movement is limited by end stops (34). At least one inner end stop (34) on the housing side limits the rotational freedom of an end wheel (32). which is in a positive fit with the drive organ (12), up to more than a full rotation. In a prestressed reduction gear (10), a switching device can comprise two spur gears (52, 54) which have identical diameter and can be driven in the opposite direction for changing the direction of movement of the drive organ (12), each of which have a pinion (50, 58) which can be displaced in the axial direction. Said pinions are in each axial position in a positive fit with the drive organ (12).

Abstract: An improved process of producing Amorolfine base, which is a compound of formula (I): said process including the steps of: (i) contacting a compound of formula (II): with a Friedel-Crafts catalyst at a temperature in the range of 20° to 30° C.; (ii) adding a 2-halogeno-2-methylbutane thereto, and wherein the reaction mixture obtained in step (i) is cooled to a temperature of from ?40° to ?60° C. prior to step (ii).