Patents by Inventor Bee-Cheng Sim

Bee-Cheng Sim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human growth hormone modified at position 35
    Patent number: 8778880
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: July 15, 2014
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human growth hormone
    Patent number: 8143216
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: March 27, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria A. Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Pegylated human interferon polypeptides
    Patent number: 8093356
    Abstract: Modified human interferon polypeptides and uses thereof are provided, including PEGylated human interferon polypeptides with one or more non-naturally encoded amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: January 10, 2012
    Assignee: Ambrx, Inc.
    Inventors: Anna-Maria A. Hays, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Modified Human Growth Hormone
    Publication number: 20110294161
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: February 25, 2011
    Publication date: December 1, 2011
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Richard D. DIMARCHI, Anna-Maria HAYS, Troy E. WILSON, Bee-Cheng SIM, David C. LITZINGER
  • Modified human growth horomone polypeptides and their uses
    Patent number: 7939496
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: May 10, 2011
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified Insulin Polypeptides and Their Uses
    Publication number: 20100298212
    Abstract: Modified insulin polypeptides and their uses thereof are provided
    Type: Application
    Filed: November 20, 2008
    Publication date: November 25, 2010
    Applicant: AMBRX, INC.
    Inventors: Zhenwei Miao, Denise Krawitz, Vadim Kraynov, Tian Feng, Bee-Cheng Sim, Lillian Skidmore, Anna-Maria A. Hays Putnam, Nick Knudesen, Michael Deguzman
  • Human Interferon Molecules and Their Uses
    Publication number: 20100135959
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: June 2, 2006
    Publication date: June 3, 2010
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. Hays Putnam, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Non-Natural Amino Acid Polypeptides Having Modified Immunogenicity
    Publication number: 20090093405
    Abstract: Non-naturally encoded amino acid polypeptides with modulated immunogenicity and uses thereof are provided.
    Type: Application
    Filed: January 18, 2007
    Publication date: April 9, 2009
    Applicant: AMBRX, INC.
    Inventors: John W. Wallen, III, Bee-Cheng Sim, Bruce Kimmel, Thomas O. Daniel
  • Modified Human Four Helical Bundle Polypeptides And Their Uses
    Publication number: 20080300163
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Application
    Filed: January 28, 2005
    Publication date: December 4, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified Human Four Helical Bundle Polypeptides and Their Uses
    Publication number: 20080207877
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Application
    Filed: April 24, 2008
    Publication date: August 28, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Richard D. DIMARCHI, Anna-Maria HAYS, Troy E. WILSON, Bee-Cheng SIM, David C. LITZINGER
  • Modified Human Four Helical Bundle Polypeptides and Their Uses
    Publication number: 20080161539
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 18, 2007
    Publication date: July 3, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Richard D. DIMARCHI, Anna-Maria HAYS, Troy E. WILSON, Bee-Cheng SIM, David C. LITZINGER
  • Modified Human Four Helical Bundle Polypeptides and Their Uses
    Publication number: 20080146781
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 18, 2007
    Publication date: June 19, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Richard D. DIMARCHI, Anna-Maria HAYS, Troy E. WILSON, Bee-Cheng SIM, David C. LITZINGER
  • Human Interferon Molecules and Their Uses
    Publication number: 20080132681
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: June 5, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. HAYS, Bruce E. KIMMEL, Ho Sung CHO, Bee-Cheng SIM, David C. LITZINGER, Roberto MARIANI, Vadim KRAYNOV, Nick Knudsen, Thomas O. DANIEL, Alan KODER, Stuart BUSSELL, Junjie LIU, Zhenwei MIAO, Theresa MORROW
  • Human Interferon Molecules and Their Uses
    Publication number: 20080119640
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 22, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. HAYS, Bruce E. KIMMEL, Ho Sung CHO, Bee-Cheng SIM, David C. LITZINGER, Roberto MARIANI, Vadim KRAYNOV, Nick Knudsen, Thomas O. DANIEL, Alan KODER, Stuart BUSSELL, Junjie LIU, Zhenwei MIAO, Theresa MORROW
  • Human Interferon Molecules and Their Uses
    Publication number: 20080108792
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria Hays, Bruce Kimmel, Ho Sung Cho, Bee-Cheng SIM, David Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20080108797
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Growth Hormone
    Publication number: 20080107680
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas Daniel, Richard DiMarchi, Anna-Maria Hays, Troy Wilson, Bee-Cheng Sim, David Litzinger
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20080103293
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Growth Hormone
    Publication number: 20080102124
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Growth Hormone
    Publication number: 20080102125
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER