Abstract: Provided herein is an endotracheal tube, and an intubation system comprising said endotracheal tube and a stylet for guiding an endotracheal tube during intubation. The endotracheal tube has a body comprising a flexible hollow tube with a distal end for insertion into a patient's trachea during intubation, and an opposite proximal end. The endotracheal tube comprises one or more internal projections, said internal projections projecting radially inwardly from an internal wall surface of a distal tip portion of the endotracheal tube, wherein the internal projections are tapered in at least one direction.

Abstract: Provided herein is an endotracheal tube, and an intubation system comprising said endotracheal tube and a stylet for guiding an endotracheal tube during intubation. The endotracheal tube has a body comprising a flexible hollow tube with a distal end for insertion into a patient's trachea during intubation, and an opposite proximal end. The endotracheal tube body comprises a polymeric material comprising a helically wound, meshed or braided reinforcement structure embedded therein, the helically wound, meshed or braided reinforcement structure being formed from one or more filaments. One or more properties of the reinforcement structure vary along the length of the endotracheal tube such that the bending flexibility and/or the mechanical strength of the endotracheal tube varies along the length of the endotracheal tube.

Abstract: A server operates between a customer and a subscriber to store data associated with the customer and data comprising media content associated with the subscriber. The server is configured to receive from the customer a request for content associated with products or services provided by the subscriber. The request is triggered by scanning a code by a user device operated by the customer. The request causes the server to retrieve customer information from data storage operated by the server. Based on the retrieved customer information and the request for content from the customer, the server retrieves personalized data associated with the subscriber. The personalized data comprises the media content associated with the subscriber that is tailored based on customer preferences stored in the server.

Abstract: Embodiments are generally directed to compression in machine learning and deep learning processing. An embodiment of an apparatus for compression of untyped data includes a graphical processing unit (GPU) including a data compression pipeline, the data compression pipeline including a data port coupled with one or more shader cores, wherein the data port is to allow transfer of untyped data without format conversion, and a 3D compression/decompression unit to provide for compression of untyped data to be stored to a memory subsystem and decompression of untyped data from the memory subsystem.

Abstract: The present invention provides a transporting device for a storage system which maximises storage capacity of the storage system whilst remaining scalable and avoiding overheads. The transporting device includes a frame having a Z-direction track and a tray for supporting the container. The tray includes an X-direction movement unit arranged to move the container in an X-direction, a Y-direction movement unit arranged to move the container in a Y-direction and a Z-direction movement unit arranged to move the tray in a Z-direction by way of interaction with the Z-direction track. The transporting device can include a frame having a Z-direction track and a first movement unit arranged to move the container in an X-direction and/or a Z-direction by with the Z-direction track. A second movement unit is arranged to move the container in a Y-direction and/or a Z-direction.

Abstract: There is provided an air-treatment device including an airflow generator for generating an airflow, an adsorbent material for adsorbing one or more airborne contaminants, the adsorbent material being arranged such that at least a portion of the airflow passes through the adsorbent material, a heater arranged to heat a portion of the adsorbent material to desorb adsorbed contaminants, and a photocatalytic reactor arranged to receive air containing the contaminants desorbed from the heated portion of adsorbent material. The photocatalytic reactor includes a photo-catalyst for photocatalytic degradation of one or more of the contaminants, and one or more light sources for illuminating the photo-catalyst to facilitate photocatalytic degradation. The air-treatment device is arranged such that at least a portion of the airflow that has not passed through the heated portion of the adsorbent material contacts the one or more light sources.

Abstract: There is provided a photocatalytic reactor arranged to receive one or more airborne contaminants. The photocatalytic reactor includes a photo-catalyst for photocatalytic degradation of one or more of the contaminants disposed on a substrate, and a light-emitting diode circuit board comprising a circuit board with one or more first light-emitting diodes mounted to a first side of the circuit board and one or more second light-emitting diodes mounted to a second side of the circuit board. The substrate is arranged to be illuminated by both the one or more first light-emitting diodes and the one or more second light-emitting diodes in order to facilitate photocatalytic degradation.

Abstract: The present disclosure discloses methods for culturing stem cells in three-dimensional methods. Said method is either a spheroid-based method or a microcarrier-based method. The process as described herein leads to the expansion of the stem cells to obtain an expanded population of the stem cells, and a stem cell derived-conditioned medium. The present disclosure also discloses an expanded population of the stem cells, and a stem cell derived-conditioned medium obtained from the process as described herein. Further, an exosome preparation obtained from the stem cell derived-conditioned medium is also disclosed herein. The present disclosure also discloses a composition comprising an expanded population of the stem cells, or a stem cell derived-conditioned medium, or an exosome preparation, or combinations thereof. Methods of treatment using the composition as described herein is also disclosed in the present disclosure.

Abstract: In one embodiment, a mobile data analysis system generates mobile reports. In this context, a mobile report represents information collected by a mobile device user and provided as input to a report form displayed by an associated mobile device. The collected information may, for example, include information relating to an activity or event, information relating to a particular person, entity, or location, or any combination thereof. A mobile report may be based on a report template. A report template defines one or more data fields and other property information to be included in a mobile report. A mobile report may be sent to a server to generate one or more data objects, and one or more data object links between the data objects from a first mobile report, the data objects from a second mobile report, and exiting data objects that are maintained at the server.

Abstract: The present disclosure provides an improved cogwheel permitting enhanced meshing of cogwheels when operating perpendicularly. Exemplary embodiments introduce a multi-cogwheel design with specific dimensions and tooth profiles to permit perpendicular engagement of cogwheels whilst permitting translation of such cogwheels.

Abstract: The present disclosure discloses a bioengineered formulation comprising: (a) a modified collagen peptide having a molecular weight in the range of 20-80 kDa, and with a degree of substitution in the range of 20-75%; and (b) a modified hyaluronic acid having a molecular weight in the range of 10-100 kDa, and with a degree of substitution in the range of 20-75%. The present disclosure also discloses the bioengineered formulation comprising stem cells, or exosomes, or combinations thereof. Further, the process for preparing the bioengineered formulation is also disclosed therein. Moreover, the formulation comprising: a) exosomes selected from the group consisting of corneal stromal stem cell derived-exosomes, primed mesenchymal stem cell derived-exosomes, and naive mesenchymal stem cell derived-exosomes; and (b) a clinically approved eye drop formulation is also provided.

Abstract: The present disclosure discloses a xeno-free bio-ink formulation amenable to be printed using a 3D printer. The bio-ink formulation exhibits optimum viscosity in the range of 1690-5300 cP. The present disclosure discloses a bio-printed corneal lenticule obtained from the bio-ink formulation. The bio-printed corneal lenticule as disclosed is of the optimum thickness in the range of 10-500 microns and exhibits transmittance in the range of 80-99%. The present disclosure also discloses a process for preparing the bio-ink formulation as well as for preparing the bio-printed corneal lenticule. Further, the present disclosure discloses a method of treating a corneal defect using the bio-printed corneal lenticule as an implant to treat the corneal defect. The bio-printed corneal lenticule can further be used as a model for in-vitro drug testing and diseases modelling.

Abstract: The present disclosure discloses embodiments of exosome compositions comprising primed mesenchymal stem cell-derived exosomes.

Abstract: The present disclosure discloses embodiments of a formulation for application to the cornea, the formulation comprising a hyaluronic acid, a gelatin, and exosomes. In certain variations, the exosomes may be naive mesenchymal stem cell-derived exosomes, primed mesenchymal stem cell derived-exosomes, or corneal stromal stem cell derived-exosomes. In certain variations, the primed mesenchymal stem cell-derived exosomes are exosomes derived from mesenchymal stem cells primed with a corneal stromal stem cell derived-conditioned medium.

Abstract: A storage system as disclosed can maximize storage capacity whilst remaining scalable. A transporting device is arranged to form a cluster with a reconfigurable physical topology. A transporting device can cooperate with a portion of a surface, and with at least one other transporting device in a cluster with a reconfigurable physical topology. An item receiving space and a relocating unit permit relocation of the transporting device within the cluster by way of interaction with the portion of the surface.

Abstract: The present disclosure provides a process for obtaining an expanded primed mesenchymal stem cell population. In the process, the MSCs are cultured in the culture medium comprising a corneal stromal stem cell derived-conditioned medium to obtain the expanded population of the primed mesenchymal stem cell population along with the mesenchymal stem cell derived-conditioned medium. Also, provided is a method of culturing the MSCs in 3D culture using a spheroid-based method or a microcarrier-based method, in order to obtain the expanded primed mesenchymal stem cell population. Further, an exosome preparation obtained from the expanded primed mesenchymal stem cell derived-conditioned medium is also disclosed herein. The present disclosure also discloses a composition comprising an expanded population of the primed mesenchymal stem cells, or a primed mesenchymal stem cell derived-conditioned medium, or an exosome preparation, or combinations thereof.

Abstract: Aspects of the present disclosure address systems and methods for clock tree synthesis (CTS). A first iteration of CTS is performed to generate an intermediate clock tree for an integrated circuit (IC) design that includes one or more macros. Target pin insertion delays (PIDs) for the one or more macros are computed based on the intermediate clock tree using a linear program. A second iteration of CTS is performed using the target PIDs for the one or more macros to generate an optimized clock tree for the IC design.

Abstract: There is provided a container maneuvering apparatus arranged to provide an interface between a container-conveying system and a container-storage system. More specifically, there is disclosed a container maneuvering apparatus arranged to load/unload a container into/from a carriage. Optionally, the carriage is a Magway carriage. The carriage can be made stationary before loading/unloading the container by the container-conveying system. The carriage and container can match velocities so that both are moving, but at the same velocity, whilst loading/unloading operations are performed by the container maneuvering apparatus.

Abstract: In one embodiment, a mobile data analysis system generates mobile reports. In this context, a mobile report represents information collected by a mobile device user and provided as input to a report form displayed by an associated mobile device. The collected information may, for example, include information relating to an activity or event, information relating to a particular person, entity, or location, or any combination thereof. A mobile report may be based on a report template. A report template defines one or more data fields and other property information to be included in a mobile report. A mobile report may be sent to a server to generate one or more data objects, and one or more data object links between the data objects from a first mobile report, the data objects from a second mobile report, and exiting data objects that are maintained at the server.