Abstract: Various aspects of the present disclosure relate to methods, apparatuses, and systems that support angle-based positioning. For instance, an angular search window and associated uncertainty for positioning (e.g., sidelink positioning) can be determined based on an approximate position and/or range of a target-UE. Further, reporting of per path measurements is provided to in multipath environments. Implementations are also provided for triggering, configuring, and reporting angle information including angle of arrival (AoA) and/or angle of departure (AoD) (e.g., sidelink AoA and/or sidelink AoD) in terms of a Global Coordinate System (GCS) and a Local Coordinate System (LCS).

Abstract: Apparatuses, methods, and systems are disclosed for RAT-independent positioning in sidelink. An apparatus (1500) includes a memory and a processor (1505) coupled to the memory (1510). The processor (1505) transmits, to at least one other device via an SL connection, a RAT-independent positioning information configuration and a RAT-independent reporting configuration. The processor (1505) receives a RAT-independent measurement and location report in response to the RAT-independent positioning information and reporting configuration. The processor (1505) detects an error related to a SL positioning assistance data configuration, measurement, and information report. The processor (1505) transmits an indication of the error and a request for supported RAT-independent positioning capabilities of the at least one other device. The processor (1505) receives a response comprising the supported RAT-independent positioning capabilities of the at least one other device.

Abstract: There is provided herein methods generating a population of primed mesenchymal stem cell-derived exosomes. A method in accordance with the disclosure may comprise expanding a population of mesenchymal stem cells (MSCs) in culture, administering one or more priming agents in the culture to prime the population of MSCs and obtain a population of primed MSCs: growing the population of die primed MCSs in culture to produce a primed-MSC-derived conditioned medium; collecting the primed MSC-conditioned medium; and purifying a population of exosomes from the primed MSC-conditioned medium. The one or more priming p agents may comprise a conditioned media derived from a population of stem cells different from the population of MSCs, a Nrf2 activator, or a combination thereof. There is also provided herein methods of treating tissues such as cornea and liver using the population of exosomes from the primed MSC-conditioned medium.

Abstract: The present disclosure provides an improved cogwheel permitting enhanced meshing of cogwheels when operating perpendicularly. Exemplary embodiments introduce a multi-cogwheel design with specific dimensions and tooth profiles to permit perpendicular engagement of cogwheels whilst permitting translation of such cogwheels.

Abstract: A fan assembly, including a fan body including an inlet surface defining an air inlet. A motor-driven impeller contained within the fan body generates an airflow. A filter assembly is arranged to removably engage with the fan body and to cover at least a portion of the inlet surface when engaged with the fan body. The filter assembly includes a filter and a housing for the filter, the housing being provided with a filter retention assembly for releasably retaining the filter in the housing, and a user interface for actuating the filter retention assembly to release the filter from the housing. Upon actuation of the filter retention assembly via the user interface, the filter is free to slide relative to the housing. Preferably, the user interface is positioned on the housing.

Abstract: A nozzle for a fan assembly is described. The nozzle includes a first duct through which a first airflow moves, the first duct having a first outlet for emitting the first airflow. The nozzle further includes a second duct through which a second airflow moves, the second duct having a second outlet for emitting the second airflow. The first and second outlets are arranged such that the first and second airflows collide to generate a combined airflow having a direction defined by the relative flow rates of the first and second airflows. The first duct then includes a portion moveable to vary the flow rate of the first airflow.

Abstract: A nozzle for a fan assembly is described. The nozzle includes a first duct through which a first airflow moves, and a second duct through which a second airflow moves. The first duct has a first outlet for emitting the first airflow, and the second duct has a second outlet for emitting the second airflow. The first and the second outlets are arranged such that the first and second airflows collide to generate a combined airflow having a direction defined by the relative flow rates of the first and second airflows. The second duct has a constant restriction, and the first duct has a variable restriction to vary the flow rate of the first airflow.

Abstract: There is provided a container maneuvering apparatus arranged to provide an interface between a container-conveying system and a container-storage system. More specifically, there is disclosed a container maneuvering apparatus arranged to load/unload a container into/from a carriage. Optionally, the carriage is a Magway carriage. The carriage can be made stationary before loading/unloading the container by the container-conveying system. The carriage and container can match velocities so that both are moving, but at the same velocity, whilst loading/unloading operations are performed by the container maneuvering apparatus.

Abstract: The present invention provides a transporting device for a storage system which maximises storage capacity of the storage system whilst remaining scalable and avoiding overheads. The transporting device includes a frame having a Z-direction track and a tray for supporting the container. The tray includes an X-direction movement unit arranged to move the container in an X-direction, a Y-direction movement unit arranged to move the container in a Y-direction and a Z-direction movement unit arranged to move the tray in a Z-direction by way of interaction with the Z-direction track. The transporting device can include a frame having a Z-direction track and a first movement unit arranged to move the container in an X-direction and/or a Z-direction by with the Z-direction track. A second movement unit is arranged to move the container in a Y-direction and/or a Z-direction.

Abstract: There is provided an air-treatment device including an airflow generator for generating an airflow, an adsorbent material for adsorbing one or more airborne contaminants, the adsorbent material being arranged such that at least a portion of the airflow passes through the adsorbent material, a heater arranged to heat a portion of the adsorbent material to desorb adsorbed contaminants, and a photocatalytic reactor arranged to receive air containing the contaminants desorbed from the heated portion of adsorbent material. The photocatalytic reactor includes a photo-catalyst for photocatalytic degradation of one or more of the contaminants, and one or more light sources for illuminating the photo-catalyst to facilitate photocatalytic degradation. The air-treatment device is arranged such that at least a portion of the airflow that has not passed through the heated portion of the adsorbent material contacts the one or more light sources.

Abstract: There is provided a photocatalytic reactor arranged to receive one or more airborne contaminants. The photocatalytic reactor includes a photo-catalyst for photocatalytic degradation of one or more of the contaminants disposed on a substrate, and a light-emitting diode circuit board comprising a circuit board with one or more first light-emitting diodes mounted to a first side of the circuit board and one or more second light-emitting diodes mounted to a second side of the circuit board. The substrate is arranged to be illuminated by both the one or more first light-emitting diodes and the one or more second light-emitting diodes in order to facilitate photocatalytic degradation.

Abstract: The present disclosure discloses methods for culturing stem cells in three-dimensional methods. Said method is either a spheroid-based method or a microcarrier-based method. The process as described herein leads to the expansion of the stem cells to obtain an expanded population of the stem cells, and a stem cell derived-conditioned medium. The present disclosure also discloses an expanded population of the stem cells, and a stem cell derived-conditioned medium obtained from the process as described herein. Further, an exosome preparation obtained from the stem cell derived-conditioned medium is also disclosed herein. The present disclosure also discloses a composition comprising an expanded population of the stem cells, or a stem cell derived-conditioned medium, or an exosome preparation, or combinations thereof. Methods of treatment using the composition as described herein is also disclosed in the present disclosure.

Abstract: In one embodiment, a mobile data analysis system generates mobile reports. In this context, a mobile report represents information collected by a mobile device user and provided as input to a report form displayed by an associated mobile device. The collected information may, for example, include information relating to an activity or event, information relating to a particular person, entity, or location, or any combination thereof. A mobile report may be based on a report template. A report template defines one or more data fields and other property information to be included in a mobile report. A mobile report may be sent to a server to generate one or more data objects, and one or more data object links between the data objects from a first mobile report, the data objects from a second mobile report, and exiting data objects that are maintained at the server.

Abstract: The present disclosure provides an improved cogwheel permitting enhanced meshing of cogwheels when operating perpendicularly. Exemplary embodiments introduce a multi-cogwheel design with specific dimensions and tooth profiles to permit perpendicular engagement of cogwheels whilst permitting translation of such cogwheels.

Abstract: The present disclosure discloses a bioengineered formulation comprising: (a) a modified collagen peptide having a molecular weight in the range of 20-80 kDa, and with a degree of substitution in the range of 20-75%; and (b) a modified hyaluronic acid having a molecular weight in the range of 10-100 kDa, and with a degree of substitution in the range of 20-75%. The present disclosure also discloses the bioengineered formulation comprising stem cells, or exosomes, or combinations thereof. Further, the process for preparing the bioengineered formulation is also disclosed therein. Moreover, the formulation comprising: a) exosomes selected from the group consisting of corneal stromal stem cell derived-exosomes, primed mesenchymal stem cell derived-exosomes, and naive mesenchymal stem cell derived-exosomes; and (b) a clinically approved eye drop formulation is also provided.

Abstract: The present disclosure discloses a xeno-free bio-ink formulation amenable to be printed using a 3D printer. The bio-ink formulation exhibits optimum viscosity in the range of 1690-5300 cP. The present disclosure discloses a bio-printed corneal lenticule obtained from the bio-ink formulation. The bio-printed corneal lenticule as disclosed is of the optimum thickness in the range of 10-500 microns and exhibits transmittance in the range of 80-99%. The present disclosure also discloses a process for preparing the bio-ink formulation as well as for preparing the bio-printed corneal lenticule. Further, the present disclosure discloses a method of treating a corneal defect using the bio-printed corneal lenticule as an implant to treat the corneal defect. The bio-printed corneal lenticule can further be used as a model for in-vitro drug testing and diseases modelling.

Abstract: The present disclosure discloses embodiments of a formulation for application to the cornea, the formulation comprising a hyaluronic acid, a gelatin, and exosomes. In certain variations, the exosomes may be naive mesenchymal stem cell-derived exosomes, primed mesenchymal stem cell derived-exosomes, or corneal stromal stem cell derived-exosomes. In certain variations, the primed mesenchymal stem cell-derived exosomes are exosomes derived from mesenchymal stem cells primed with a corneal stromal stem cell derived-conditioned medium.

Abstract: The present disclosure discloses embodiments of exosome compositions comprising primed mesenchymal stem cell-derived exosomes.

Abstract: A storage system as disclosed can maximize storage capacity whilst remaining scalable. A transporting device is arranged to form a cluster with a reconfigurable physical topology. A transporting device can cooperate with a portion of a surface, and with at least one other transporting device in a cluster with a reconfigurable physical topology. An item receiving space and a relocating unit permit relocation of the transporting device within the cluster by way of interaction with the portion of the surface.