Abstract: Diagnosis, treatment and prophylaxis of diseases and conditions associated with smooth muscle cell (SMC) dysfunction are provided through the inhibition or IL-11-mediated signalling.

Abstract: Systems and methods of repairing tissue are disclosed. Systems and methods may repair an opening through a hip capsule. Systems and methods preferably repair the tissue while minimally encroaching on the tissue immediately behind the repair, such as the hip joint tissues. Some systems may repair the tissue with a suture passer having a needle that slides in axial alignment with the passer and includes a first recess for passing the suture in a first axial direction and a second recess for passing the suture in an opposing axial direction. Some systems may pass a portion of a repair construct in a retrograde direction, placing the repair construct in a preferred arrangement accommodating for the stresses on the tissue.

Abstract: According to one aspect, a method includes detecting, through a detection interface of a vehicle, an installation of a first compartment insert in a first compartment of the vehicle, wherein detecting the installation includes determining when the detection interface is in contact with a second interface of the first compartment insert. After detecting the installation of the first compartment insert, it is determined whether the first compartment insert is capable of transmitting information to the vehicle. The method also includes obtaining the information from the first compartment insert when it is determined that the first compartment insert is capable of transmitting the information to the vehicle, and identifying a type associated with the first compartment insert from the information.

Abstract: Systems, apparatuses, and methods for providing negative pressure and/or instillation fluids to a tissue site. Some embodiments are illustrative of an apparatus or system for delivering negative-pressure and/or therapeutic solution of fluids to a tissue site, which can be used in conjunction with sensing properties of fluids extracted from a tissue site and/or instilled at a tissue site. For example, an apparatus includes a dressing interface or connector that includes a pH sensor, a humidity sensor, a temperature sensor and/or a pressure sensor embodied on a single pad within the connector and proximate the tissue site to provide data indicative of acidity, humidity, temperature and pressure. Such apparatus includes algorithms for processing such data for detecting leakage and blockage as well as providing information relating to the progression of healing of wounds at the tissue site.

Abstract: This invention concerns a sole element for a cleated article of footwear, in particular for a football shoe. The sole element includes a composite element with an anisotropic bending property. The sole element further includes a polymer element, and the polymer element at least partially covers the composite element of the sole element.

Abstract: In some illustrative examples, a bridge suitable for treating a tissue site may include a bridge sealing member and one or more bridge wicking layers. The bridge sealing member may extend along a length of the bridge, and may define an internal passageway in fluid communication between a receiving end of the bridge and a transmitting end of the bridge. The one or more bridge wicking layers may be disposed within the internal passageway of the bridge sealing member. Other apparatus, systems, and methods are disclosed.

Abstract: A method, system, and computer program product for bit flip aware latch placement in integrated circuit generation are provided. The method identifies a chip design for an integrated circuit. A set of chip design constraints, associated with the chip design, is identified. A set of checking groups, associated with a plurality of latches to be placed in the chip design, is determined. Based on the set of chip design constraints and the set of checking groups, a placement scheme for the plurality of latches is selected. The method places the plurality of latches within the chip design based on the placement scheme and the set of checking groups.

Abstract: A portable temperature-controlled device includes a housing and a controllable temperature element having a first surface and a second surface, wherein the first surface opposes the second surface. Inside the housing, a heat sink is disposed and in contact with the first surface of the controllable temperature element, and a fan is disposed adjacent the heat sink inside the housing and configured to direct heat away from the heat sink. The portable temperature-controlled device further includes a heat spreader in contact with the controllable temperature element for thermal energy transfer. The heat sink and the fan are supported on a support member inside the housing.

Abstract: Aspiration medical device as well as methods for making and using aspiration medical devices are disclosed. An example aspiration medical device may include a tubular member having a distal end region and defining an inflow orifice adjacent to the distal end region. An aspiration member may be disposed within the tubular member. The aspiration member may have a plurality of axially-spaced fluid jets formed therein.

Abstract: A photovoltaic (PV) system can include a plurality of PV modules and circuitry configured to receive an indication of a status of the PV system and to, in response to the indication, determine whether to switch between a first state in which the PV modules output DC power and a second state in which the PV modules do not output power.

Abstract: This disclosure relates to an assembly and method for attaching a heliostat to a foundation in a tower-based solar thermal CSP installation. A heliostat securing assembly for securing a heliostat to a tubular foundation post comprises an insert locatable within an upper opening in the foundation post, the insert defining an aperture for receiving a support shaft of the heliostat. A clamp arrangement, for locating the insert in the upper opening in the foundation post, has at least one inner or outer bearing surface configured to bear against at least one corresponding outer or inner bearing surface of the insert. One or more urging connectors, for connecting the insert and the clamp arrangement, is operable to urge at least one of the insert and the clamp arrangement toward the other in an axial direction of the foundation post.

Abstract: A method for conveying a data message using a public ledger includes: generating, by a generation module of a processing server, a data message, wherein the data message comprises one or more data values; electronically transmitting, by a transmitting device of the processing server, a data signal superimposed with the generated data message to a first computing system; receiving, by a receiving device of the processing server, a data signal superimposed with an encrypted message from the first computing system, wherein the encrypted message is generated via application of one or more encryption algorithms to the generated data message using at least one encryption key; appending, by the generation module of the processing server, an identification value to the encrypted message; and submitting, by the transmitting device of the processing server, the appended encrypted message to a public ledger associated with a second computing system.

Abstract: This disclosure describes devices, systems, and methods related to two-piece dressings. In one aspect, a two-piece dressing includes a drape including a first light switchable adhesive, and a pad. The pad includes a second light switchable adhesive configured to couple the pad to the drape and a light source configured to emit light and activate at least the second light switchable adhesive. In another aspect a two-piece dressing includes a drape and a pad. The pad is configured to be coupled to the drape and to a light source, and the pad includes a light switchable adhesive configured to couple the pad to the drape. The light source is configured to emit light to activate the light switchable adhesive to decouple the pad from the drape, and the pad is configured to direct the light to activate second light switchable adhesive to decouple the drape from a tissue site.

Abstract: Various methods, apparatuses/systems, and media for automatically protecting sensitive information data entering application logs, events, metrics, traces, or other outputs are disclosed. A processor receives source code associated with an application being developed; parses the source code and identifies variables or fields in the source code that include sensitive information data; applies artificial intelligence or machine learning algorithm to the source code to automatically identify variables that contain the sensitive information data based on the identified variables or fields and annotating accordingly. Each annotation is a hint that data associated with corresponding annotation is confidential and sensitive information that should not be published, logged, or printed.

Abstract: A beam layout is optimised for a given traffic distribution and network state by determining optimum beam centre positions and generating a beam layout so as to meet system requirements and minimise the distances of locations within a coverage area from the optimum beam centre positions. Adjacent beams in low traffic areas may be merged.

Abstract: A device for retaining a bicycle chain on a sprocket includes a base plate defining a plurality of fastener openings centered on an origin. A center of each of the plurality of fastener openings is disposed at a first radial distance from the origin. The origin defines an axis extending substantially orthogonally from a plane defined by two lines extending from the origin and at least two centers of the centers of the plurality of fastener openings. A first guard is secured to the base plate and includes a first guard retaining surface including a first curved surface defined by a second radial distance from the axis that is greater than the first radial distance and a first guard guiding surface having a first end adjacent the first guard retaining surface and a second end distal from the first end. The first end is disposed at the second radial distance from the axis. The second end is disposed at a third radial distance from the axis. The third radial distance is greater than the second radial distance.

Abstract: A collapsible pet crate that is easy to operate, aesthetically pleasing, quiet, light, durable, easy to clean, and safe and comfortable for the animal. Also disclosed herein are methods of operating a collapsible pet crate. The collapsible pet crate disclosed herein can further include one-step operation, environmentally safe and pet-friendly materials, and method to include various pet-friendly accessories.

Abstract: An outsole for a shoe including first and second sole segments that overlap at least partially. The first sole segment can include at least one stud and be arranged at least in a mid-foot portion of the outsole. The second sole segment can include at least one stud and be arranged at least in a toe portion of the outsole. In some embodiments, the outsole can include a first cushion element arranged between the first sole segment and the second sole segment and overlapping with at least one first stud of the first or second sole segment. In some embodiments, the outsole can include a second cushion element being arranged between the first sole segment and the second sole segment and overlapping with at least one second stud of the first or second sole segment. In some embodiments, the outsole may be an outsole for a football shoe.