Patents by Inventor Benjamin Alexander

Benjamin Alexander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9477700
    Abstract: A method of and system for monitoring and providing notification of changes to a data environment. Parameters of interest for monitoring changes made to a metadata data store are stored. Instructions are stored related to notifying a recipient of a communication about the changes. The metadata is monitored for changes related to the parameters of interest, and a change notification communication is generated with transmission initiated to the recipient. The instructions related to notification of the changes may include the identity of a recipient, mechanism for notification, and format and content of notification. A computer readable memory system and a computer program product may be provided that is encoded with a data structure for notifying data consumers of changes to a data environment that includes metadata.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: October 25, 2016
    Assignee: BANK OF AMERICA CORPORATION
    Inventors: Richard M. Wilson, Eric B. Stanley, Benjamin Alexander Leeson
  • Patent number: 9471618
    Abstract: A method of and system for monitoring and providing notification of changes to a data environment. Parameters of interest for monitoring changes made to a metadata data store are stored. Instructions are stored related to notifying a recipient of a communication about the changes. The metadata is monitored for changes related to the parameters of interest, and a change notification communication is generated with transmission initiated to the recipient. The instructions related to notification of the changes may include the identity of a recipient, mechanism for notification, and format and content of notification. A computer readable memory system and a computer program product may be provided that is encoded with a data structure for notifying data consumers of changes to a data environment that includes metadata.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: October 18, 2016
    Assignee: BANK OF AMERICA CORPORATION
    Inventors: Richard M. Wilson, Eric B. Stanley, Benjamin Alexander Leeson
  • Publication number: 20160280729
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are nucleoside analogs of Formula I: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein Base, Z1 Z2, Z3, Z4, V, W, X, Y, Ar, R1 and R2 are as described herein.
    Type: Application
    Filed: November 19, 2014
    Publication date: September 29, 2016
    Applicant: IDENIX PHARMACEUTICALS LLC
    Inventors: Adel M. Moussa, Alistair James Stewart, Benjamin Alexander Mayes
  • Publication number: 20160271162
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are D-alanine phosphoramidate pronucleotides of 2?-methyl 2?-fluoro guanosine nucleoside which display remarkable efficacy and bioavailability for the treatment of for example, HCV infection in a human. In certain embodiments, the compounds are of Formula I or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof; where W and R are as described herein.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 22, 2016
    Applicant: IDENIX PHARMACUETICALS, LLC
    Inventors: Adel M. Moussa, Benjamin Alexander Mayes, Alistair James Stewart
  • Publication number: 20160162533
    Abstract: A method of and system for monitoring and providing notification of changes to a data environment. Parameters of interest for monitoring changes made to a metadata data store are stored. Instructions are stored related to notifying a recipient of a communication about the changes. The metadata is monitored for changes related to the parameters of interest, and a change notification communication is generated with transmission initiated to the recipient. The instructions related to notification of the changes may include the identity of a recipient, mechanism for notification, and format and content of notification. A computer readable memory system and a computer program product may be provided that is encoded with a data structure for notifying data consumers of changes to a data environment that includes metadata.
    Type: Application
    Filed: February 16, 2016
    Publication date: June 9, 2016
    Inventors: Richard M. Wilson, Eric B. Stanley, Benjamin Alexander Leeson
  • Publication number: 20160162534
    Abstract: A method of and system for monitoring and providing notification of changes to a data environment. Parameters of interest for monitoring changes made to a metadata data store are stored. Instructions are stored related to notifying a recipient of a communication about the changes. The metadata is monitored for changes related to the parameters of interest, and a change notification communication is generated with transmission initiated to the recipient. The instructions related to notification of the changes may include the identity of a recipient, mechanism for notification, and format and content of notification. A computer readable memory system and a computer program product may be provided that is encoded with a data structure for notifying data consumers of changes to a data environment that includes metadata.
    Type: Application
    Filed: February 16, 2016
    Publication date: June 9, 2016
    Inventors: Richard M. Wilson, Eric B. Stanley, Benjamin Alexander Leeson
  • Patent number: 9339541
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, the compounds are according to Formula 2001: where PD, Base, RA and RB are as provided herein. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: May 17, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Cyril B. Dousson, Benjamin Alexander Mayes, David Dukhan, Adel M. Moussa, Alistair James Stewart
  • Patent number: 9330197
    Abstract: A method of and system for monitoring and providing notification of changes to a data environment. Parameters of interest for monitoring changes made to a metadata data store are stored. Instructions are stored related to notifying a recipient of a communication about the changes. The metadata is monitored for changes related to the parameters of interest, and a change notification communication is generated with transmission initiated to the recipient. The instructions related to notification of the changes may include the identity of a recipient, mechanism for notification, and format and content of notification. A computer readable memory system and a computer program product may be provided that is encoded with a data structure for notifying data consumers of changes to a data environment that includes metadata.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: May 3, 2016
    Assignee: Bank of America Corporation
    Inventors: Richard M. Wilson, Eric B. Stanley, Benjamin Alexander Leeson
  • Publication number: 20160113956
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2?-cyano, azido or amino nucleosides according to Formula 1001 or 2001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form, or polymorphic form thereof, wherein Base, W, R1 and R2 are as described herein.
    Type: Application
    Filed: September 25, 2015
    Publication date: April 28, 2016
    Inventors: David DUKHAN, Christophe Claude PARSY, Gilles GOSSELIN, Jean-François GRIFFON, Guillaume BRANDT, Cyril B. DOUSSON, Adel M. Moussa, Benjamin Alexander Mayes, Alistair James Stewart
  • Publication number: 20160118934
    Abstract: A photovoltaic (PV) system can include a plurality of PV modules and circuitry configured to receive an indication of a status of the PV system and to, in response to the indication, determine whether to switch between a first state in which the PV modules output DC power and a second state in which the PV modules do not output power.
    Type: Application
    Filed: June 23, 2015
    Publication date: April 28, 2016
    Inventors: Benjamin Alexander Johnson, Andrew Joseph Ponec
  • Patent number: 9309275
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 3?-deoxy nucleoside compounds according to Formula 3001a or 3001b: or a pharmaceutically acceptable salts, solvates, stereoisomeric forms, tautomeric forms, or polymorphic forms thereof, wherein PD, Base1 and Base2 are as provided herein.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: April 12, 2016
    Assignees: IDENIX PHARMACEUTICALS LLC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ MONTPELLIER 2 SCIENCES ET TECHNIQUES
    Inventors: Alistair James Stewart, Adel M. Moussa, Benjamin Alexander Mayes, Francois-Rene Alexandre, Dominique Surleraux, Christophe Claude Parsy, Claire Pierra, David Dukhan, Gilles Gosselin
  • Publication number: 20160098541
    Abstract: System and method to determine a reduced cohort criteria, the method including: defining N selection criteria to select a cohort from among a universe of patient data; querying a patient database, by use of a processor, and by use of the N selection criteria, in order to define a full patient population; selecting a subset of size M of the N selection criteria, to produce a subset criteria; selecting a permutation of the subset criteria, to produce a permuted subset criteria in a predetermined order; for each member of the permuted subset criteria: querying the patient database by use of the member of the permuted subset criteria to produce a respective interim patient population; combining all respective interim patient populations to produce a partial patient population; and calculating, by a processor, a coverage figure of merit that compares the partial patient population to the full patient population.
    Type: Application
    Filed: October 6, 2014
    Publication date: April 7, 2016
    Inventors: Thomas Paul Haskell, Benjamin Alexander Paul Hughes
  • Publication number: 20160082030
    Abstract: Provided herein are compounds, compositions, and methods for the treatment of viral infections, for example, Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are D-amino acid phosphoramidate halogeno pyrimidine nucleoside analog compounds which display remarkable efficacy and bioavailability for the treatment of, for example, HCV infection in a human. In certain embodiments, the compounds are of Formula I: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form, or polymorphic form thereof, wherein: PD, X, R1, R2, RA, and RB are as described herein.
    Type: Application
    Filed: November 30, 2015
    Publication date: March 24, 2016
    Inventors: Benjamin Alexander Mayes, Adel M. MOUSSA, Cyril B. DOUSSON, Gilles GOSSELIN, Claire PIERRA, David DUKHAN
  • Publication number: 20160083413
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2?-chloro nucleosides according to Formula 2001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, Z and PD are as described herein.
    Type: Application
    Filed: October 22, 2015
    Publication date: March 24, 2016
    Inventors: Gilles Gosselin, Christophe Claude Parsy, François-René Alexandre, Houcine Rahali, Jean-François Griffon, Dominique Surleraux, Cyril B. Dousson, Claire Pierra, Adel M. Moussa, Benjamin Alexander Mayes, Alistair James Stewart, David Dukhan
  • Publication number: 20160002281
    Abstract: Provided herein are compounds, compositions and methods for the treatment of liver disease and conditions, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents.
    Type: Application
    Filed: September 16, 2015
    Publication date: January 7, 2016
    Inventors: Benjamin Alexander MAYES, Adel M. MOUSSA, Alistair James STEWART, Gilles GOSSELIN, Christophe Claude PARSY, François-René ALEXANDRE, Jean-François GRIFFON, Dominique SURLERAUX, Cyril B. DOUSSON, Claire PIERRA, Houcine RAHALI
  • Patent number: 9211300
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are according to Formula 1501: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, PD, RA, RB, RC, L, M and Z are as described herein.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: December 15, 2015
    Assignees: Idenix Pharmaceuticals LLC, Centre National De La Recherche Scientifique, Universite Montpellier 2 Sciences et Techniques
    Inventors: Benjamin Alexander Mayes, Adel M. Moussa, Alistair James Stewart, Gilles Gosselin
  • Patent number: 9192621
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, provided herein are compounds according to Formula 1001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein Base, Y, Z, A, RC and RD are as described herein.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: November 24, 2015
    Assignee: IDENIX PHARMACEUTICALS LLC
    Inventors: Benjamin Alexander Mayes, Adel M. Moussa
  • Patent number: 9187515
    Abstract: Provided herein are compounds, methods and pharmaceutical compositions for use in treatment of viral infections, including hepatitis C virus (HCV) infections, in hosts in need thereof. In certain embodiments, the compounds are 2?,4?-fluoro nucleosides according to Formula 1001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form, or polymorphic form thereof, wherein Base, RA, and PD are as described herein. In certain embodiments, 2?,4?-fluoro nucleosides are provided which display remarkable efficacy and bioavailability for the treatment of, for example, HCV infection in a human.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: November 17, 2015
    Assignee: IDENIX PHARMACEUTICALS LLC
    Inventors: Benjamin Alexander Mayes, Adel M. Moussa, Alistair James Stewart
  • Patent number: 9146005
    Abstract: One embodiment of a portable media equipment support device comprising a hollow shaft having a first shaft end and a second shaft end. A manually rotatable handle is operatively mounted relative to the first shaft end and a mounting device rotational actuator is operatively mounted to the second shaft end. The manually rotatable handle is connected to mounting device rotational actuator by a drive rod internally running through said hollow shaft. A bevel gear system is internally located in said rotational actuator and used to translate motion approximately 90 degrees into a media mounting device. The media mounting device is used to secure and carry a media equipment element. The rotatable handle serves to control the motion of the drive rod and is thereby translated by the bevel gear system. This sequence of mechanical reactions is used to facilitate at least one of the panning or tilting motions of the media equipment.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: September 29, 2015
    Inventor: Benjamin Alexander Swanson
  • Patent number: 9109001
    Abstract: Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: August 18, 2015
    Assignee: IDENIX PHARMACEUTICALS, INC.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Cyril B. Dousson, David Dukhan, Claire Pierra, Dominique Surleraux, Benjamin Alexander Mayes, Adel M. Moussa, Alistair James Stewart