Abstract: In various embodiments, methods and systems are provide for detecting a physical configuration of a device based on sensor data from one or more configuration sensors. The physical configuration includes a position of a first display region of the device with respect to a second display region of the device, where the position is physically adjustable. A configuration profile is selected from a plurality of configuration profiles based on the detected physical configuration of the device. Each configuration profile is a representation of at least one respective physical configuration of the device. An interaction mode corresponding to the selected configuration profile is activated, where the interaction mode includes a set of mode input/output (I/O) features available while the interaction mode is active. Device interfaces of the device are managed using at least some mode I/O features in the set of mode I/O features based on the activating of the interaction mode.

Abstract: A dispenser (1) suitable for delivery of a cream, gel or soft solid composition comprising: (vi) a convex applicator surface (6) at an upper end; (vii) a replaceable cartridge (12) containing a composition to be dispensed; (viii) a passageway between the cartridge and the applicator surface; (ix) a drive mechanism for forcing the composition from the cartridge through the passageway and onto the applicator surface; and (x) an outer body (3) containing features (ii) to (iv); the drive mechanism comprising a dial unit (4) and a plunger (47), rotation of the dial unit (4) in a first direction advancing the plunger (47) axially upwards, the plunger (47) acting upon a piston seal (8) at the base of the replaceable cartridge (12), thereby forcing the contained composition upwards and outwards through the passageway and onto the applicator surface (6); rotation of the dial unit (4) in a second direction, counter to the first, rotationally re-setting the dial unit (4) relative to the plunger (47) in readiness for a f

Abstract: An antiperspirant composition and a dispenser therefor, the composition being a gel, cream or soft solid of viscosity from 3000 mPa·s to 5200 mPa·s at a shear rate of 16/s comprising a non-pore blocking inhibitor of perspiration and the dispenser comprising a dome-shaped applicator surface of radius of curvature decreasing from a maximum of from 25 to 60 mm at its top/center to a value of from 75 to 95% of its maximum value at a distance of 1 cm from its top/center.

Abstract: Conventional stereo audio recordings do not factor in natural ear spacing or “head shadow” of a user's head and ears. The hinged computing devices disclosed herein incorporate a pair of microphones that approximate the user's ear-to-ear spacing and orientation, as well as a physical structure that approximates the user's head shadow. A resulting recording of the computing device's environment may be conditioned and reproduced as a binaural stereo audio feed for selective playback to the user or other users.

Abstract: Conventional stereo audio recordings do not factor in natural ear spacing or “head shadow” of a user's head and ears. The hinged computing devices disclosed herein incorporate a pair of microphones that approximate the user's ear-to-ear spacing and orientation, as well as a physical structure that approximates the user's head shadow. A resulting recording of the computing device's environment may be conditioned and reproduced as a binaural stereo audio feed for selective playback to the user or other users.

Abstract: The present invention provides materials and methods for modulating an immune response. In one embodiment, the present invention provides an initial artificial lymph-node homing environment, and a simultaneous, or subsequent, artificial spleen environment leading to the resolution of the activated immune responses. In one specific embodiment, the present invention can be used to prevent and/or treat pathogenic infection, cancer, allergenic reactions, and/or unwanted immune or auto-immune responses.

Abstract: The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.

Abstract: The present invention provides materials and methods for modulating an immune response. In one embodiment, the present invention provides an initial artificial lymph-node homing environment, and a simultaneous, or subsequent, artificial spleen environment leading to the resolution of the activated immune responses. In one specific embodiment, the present invention can be used to prevent and/or treat pathogenic infection, cancer, allergenic reactions, and/or unwanted immune or auto-immune responses.

Abstract: The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.

Abstract: In various embodiments, methods and systems are provide for detecting a physical configuration of a device based on sensor data from one or more configuration sensors. The physical configuration includes a position of a first display region of the device with respect to a second display region of the device, where the position is physically adjustable. A configuration profile is selected from a plurality of configuration profiles based on the detected physical configuration of the device. Each configuration profile is a representation of at least one respective physical configuration of the device. An interaction mode corresponding to the selected configuration profile is activated, where the interaction mode includes a set of mode input/output (I/O) features available while the interaction mode is active. Device interfaces of the device are managed using at least some mode I/O features in the set of mode I/O features based on the activating of the interaction mode.

Abstract: A night vision imaging system (NVIS) compatible liquid crystal display (LCD) includes a backlight and an LCD panel. The LCD panel includes a color filter including a plurality of colored pixels. Each of the colored pixels in the plurality of colored pixels incorporates a near infrared (NIR) filter, capable of substantially blocking emissions from the backlight, including NIR emission between 650 nm and 930 nm, while maintaining high transmission of bands of visible light for producing a full color visual image.

Abstract: Broadly speaking, the technology relates to using wave field synthesis theory to simulate one or more idealized virtual point sources in a multi-speaker system. The speaker transfer function of each speaker is modeled, and the values and directional gradient of the combined speaker transfer function at test points in a convexly-bounded listening region are compared to the desired values and directional gradient for the idealized transfer function of the idealized virtual point source(s) at the test points to determine filter coefficient sets for each filter. The determined filter coefficients are those which minimize the total difference between the values and directional gradient of the combined speaker transfer function and the values and directional gradient of the idealized transfer function of the idealized virtual point source across all the test points for a plurality of frequency bins.

Abstract: An antiperspirant composition and a dispenser therefor, the composition being a gel, cream or soft solid of viscosity from 3000 mPa·s to 5200 mPa·s at a shear rate of 16/s comprising a non-pore blocking inhibitor of perspiration and the dispenser comprising a dome-shaped applicator surface of radius of curvature decreasing from a maximum of from 25 to 60 mm at its top/centre to a value of from 75 to 95% of its maximum value at a distance of 1 cm from its top/centre.

Abstract: A dispenser (1) suitable for delivery of a cream, gel or soft solid composition comprising: (vi) a convex applicator surface (6) at an upper end; (vii) a replaceable cartridge (12) containing a composition to be dispensed; (viii) a passageway between the cartridge and the applicator surface; (ix) a drive mechanism for forcing the composition from the cartridge through the passageway and onto the applicator surface; and (x) an outer body (3) containing features (ii) to (iv); the drive mechanism comprising a dial unit (4) and a plunger (47), rotation of the dial unit (4) in a first direction advancing the plunger (47) axially upwards, the plunger (47) acting upon a piston seal (8) at the base of the replaceable cartridge (12), thereby forcing the contained composition upwards and outwards through the passageway and onto the applicator surface (6); rotation of the dial unit (4) in a second direction, counter to the first, rotationally re-setting the dial unit (4) relative to the plunger (47) in readiness for a f

Abstract: Disclosed herein is a non-toxic, bioresorbable, magnesium based alloy for use in production of implants. Specifically exemplified herein are alloy embodiments useful for orthopedic implants. Also disclosed are alloy materials that incorporate magnesium, calcium and strontium.

Abstract: Embodiments of the present disclosure provide for arrays, systems, and methods analyzing cells, methods of making arrays, and the like.

Abstract: A rigid electrical panel has both a flexible printed circuit and an electrically conductive grounding layer embedded therein. The electrically conductive grounding layer is electrically connected to a grounding insert which is also embedded in the rigid material. The grounding insert has a base portion and an exposed portion. The electrically conductive grounding layer is connected to the base portion, and the exposed portion allows the grounding insert, and thus the electrically conductive grounding layer, to be electrically connected to a grounding point, for example on a gas turbine engine.