Abstract: An endovascular spiral coil coating and methods of making and using the same.

Abstract: Systems and methods are disclosed for intra-oral delivery of drugs.

Abstract: Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.

Abstract: Systems and methods are disclosed for intra-oral delivery of drugs.

Abstract: Systems and methods are disclosed for intra-oral delivery of drugs. One method embodiment includes providing a dental device with one or more reservoirs, supplying at least one of the reservoirs with the one or more substances, and fluidly releasing the one or more substances from at least one reservoir into an oral structure at different preselected doses at different predetermined time periods and in a predetermined sequence.

Abstract: Devices, systems, and methods are disclosed for intra-orally diagnosing a body condition.

Abstract: An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.

Abstract: An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.

Abstract: Systems and methods are disclosed for detecting or diagnosing diseases by sampling and testing intra-oral fluids.

Abstract: An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.

Abstract: An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.

Abstract: An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.

Abstract: Systems and methods are disclosed for intra-oral delivery of drugs.

Abstract: Devices for fabricating oriented polymer fibers, and methods for fabricating thereof by electropulling, are provided.

Abstract: Devices, systems, and methods are disclosed for intra-orally diagnosing a body condition.

Abstract: Customized implants for use in reconstructive bone surgeries where anatomical accuracy and bone adaptation are important, such as plastic and craniomaxillofacial reconstructions. This implant comprises a porous surface layer and a tough inner core of interpenetrating phase composite. The porous surface layer enhances the biocompatibility, tissue ingrowth, and implant stability. The tough inner core improves the mechanical properties of the implant with a high fracture toughness and a low modulus. The anatomical accuracy of the implants will minimize the intra-operative manipulation required to maintain a stable host bone-implant interface.

Abstract: Customized implants for use in reconstructive bone surgeries where anatomical accuracy and bone adaptation are important, such as plastic and craniomaxillofacial reconstructions. This implant comprises a porous surface layer and a tough inner core of interpenetrating phase composite. The porous surface layer enhances the biocompatibility, tissue ingrowth, and implant stability. The tough inner core improves the mechanical properties of the implant with a high fracture toughness and a low modulus. The anatomical accuracy of the implants will minimize the intra-operative manipulation required to maintain a stable host bone-implant interface.

Abstract: Customized implants for use in reconstructive bone surgeries where anatomical accuracy and bone adaptation are important, such as plastic and craniomaxillofacial reconstructions. This implant comprises a porous surface layer and a tough inner core of interpenetrating phase composite. The porous surface layer enhances the biocompatibility, tissue ingrowth, and implant stability. The tough inner core improves the mechanical properties of the implant with a high fracture toughness and a low modulus. The anatomical accuracy of the implants will minimize the intra-operative manipulation required to maintain a stable host bone-implant interface.