Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: A method of fabricating a multijunction solar cell panel by providing a plurality of multijunction solar cells; dispensing out uncured silicone coating on the solar cells using an automated process with visual recognition, and curing the silicone coating on the solar cell to complete the Cell-Interconnect-Cover Glass (CIC) assembly.

Abstract: A vehicle mounted spreader for spreading materials such as sand, salt, or other granular chemicals onto snow and ice covered road surfaces comprises a hopper for containing the material to be spread, a spinner for spreading the material, a conveyor for conveying the material from the hopper to the spinner, a vehicle speed sensor, a load sensor, and a controller programmed with an intended density of material (e.g., pounds per acre) and desired width of coverage; within the controller the vehicle speed sensor measurement and load sensor inputs are processed to generate outputs to control the speed of the conveyor and spinner, to both control the rate of material distribution and the pattern of material distribution to approach the intended density and width.

Abstract: A pneumatic robotic tool, such as grinder, sander, etc., implements passive force control and compliance using two or more double-acting pneumatic pistons distributed about a pneumatic motor within the tool housing. The multiple pistons facilitate a compact design, reducing tool stack height, as compared to prior-art, single-piston designs. In one embodiment, filtered breather vents and an air pressure equalization passage maintain ambient atmospheric pressure throughout the tool, while preventing the infiltration of dust and other particulates. In one embodiment, a hard port rigidly affixed to the tool housing is provided for at least motor supply pneumatic fluid. The motor supply air is transferred from the hard port to the pneumatic motor via a flexible pneumatic fluid tube within the tool housing. In one embodiment, the pneumatic motor discharge air is vented from the tool housing in a sealed passage that accommodates the tool compliance motion, and prevents dust infiltration.

Abstract: The present invention relates to compounds of formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: wherein X1, X2, R1, R2, R30, R31 and Ring A are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.

Abstract: A system that may include a bus bar that may include a mounting bracket configured to electrically couple the bus bar to a motor. The mounting bracket may also be configured to be removably coupled to the motor with at least one fastener. A transducer may be electrically coupled to the bus bar and have transducer elements. A dielectric material may be disposed between the bus bar and the transducer to prevent debris from contacting the active transducer elements and electrical arcing from occurring.

Abstract: There is provided a method of manufacturing sachets. The method involves moving a web of semi-rigid material through a cutting station and simultaneously cutting a discrete cut in the web of semi-rigid material while the web of semi-rigid material continues to move through the cutting station. The method also includes sandwiching the web of semi-rigid material between a first flexible web of material and a second web of flexible material such that the first web of flexible material seals the discrete cuts in the semi-rigid web of material and the second web of flexible material forms a continuous elongate reservoir with the web of semi-rigid material. There is also provided an apparatus for cutting a web of material. The apparatus has a cutting roller and at least one cutting element protruding beyond the exterior surface of the roller, wherein the cutting element has a cutting profile that is at least partly a zigzag shape.

Abstract: A method of collecting visual data using a mobile image capture device is provided. The method comprises the steps of: capturing image data with the mobile image capture device and associating time and location data with each image; and storing the image data and associated time and location data. The method further comprises monitoring the position and orientation of the image capture device. The method further comprises: defining an area surrounding or next to the location of the mobile image capture device; and identifying a characteristic of the defined area based on one or more of: the density of the image data in the area; the age of the image data in the area; and/or data demand values associated with locations within the defined area. The timing of capture of image data is based on the characteristic of the defined area.

Abstract: A system for improving drill bit performance, having processors and memory storing instructions to obtain a wear report for a drill bit, wherein the wear report includes wear characteristics of the drill bit and drill operating parameters under which the drill bit was used; compare the wear characteristics of the drill bit to a threshold for acceptable drill bit wear; and adjust drill operating parameters based on the wear characteristics of the drill bit. The instructions to obtain the wear report for the drill bit include instructions to analyze images of the drill bit to identify wear characteristics; identify wear patterns based on the wear characteristics of the drill bit; identify probable drilling conditions based on the wear patterns; and generate the wear report for the drill bit based on the images of the drill bit, the wear characteristics of the drill bit, and the probable drilling conditions.

Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided.

Abstract: A fluid management system and method includes a thermal management system disposed within a housing that includes conduits extending between a source and a destination of a first fluid. The first fluid exchanges heat with cooling devices as the first fluid moves between the source and the destination. A fluid mixture including the first fluid and a second fluid, and an exhaust are generated responsive to the first fluid exchanging heat with the cooling devices. The exhaust directed toward an outlet of the housing. A separator assembly fluidly coupled with and disposed downstream of the thermal management system receives the fluid mixture and separates the first fluid from the second fluid. The first fluid is directed in a first direction out of the separator assembly and the second fluid is directed toward the outlet to be combined with the exhaust.

Abstract: A rack system for a vehicle and method of operating same includes an upright support bracket and a stability bracket. The upright support bracket has upper and lower portions with the upper portion having a bracket body and a bracket channel, and the lower portion configured to removably attach to the vehicle. The stability bracket has a shelf projection and a bracket base. The shelf projection extends from the bracket base and has a shelf bottom. The bracket base of the stability bracket is configured to be removably secure to the bracket body of the upright support bracket within the bracket channel of the upright support bracket in a predetermined position such that the shelf bottom is configured to support a mounting bar thereon.

Abstract: The present invention relates to compounds of formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: wherein X1, X2, R1, R2, R30, R31 and Ring A are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.

Abstract: A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.

Abstract: The invention provides methods of treating cancer and methods for selecting approaches for treatment of cancer.

Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: A method of fabricating a multijunction solar cell by providing a plurality of multijunction solar cells; dispensing an uncured silicone coating on the solar cells using an automated process with visual recognition, and curing the silicone coating on the solar cell.

Abstract: An in vitro microfluidic gut-on-chip is described herein that mimics the structure and at least one function of specific areas of the gastrointestinal system in vivo. In particular, a multicellular, layered, microfluidic culture is described, allowing for interactions between lamina propria-derived cells and gastrointestinal epithelial cells and endothelial cells. This in vitro microfluidic system can be used for modeling inflammatory gastrointestinal tissue, e.g., Crohn's disease, colitis and other inflammatory gastrointestinal disorders. These multicellular, layered microfluidic gut-on-chip further allow for comparisons between types of gastrointestinal tissues, e.g., small intestinal deuodejeum, small intestinal ileium, large intestinal colon, etc., and between disease states of gastrointestinal tissue, i.e. healthy, pre-disease and diseased areas.

Abstract: An in vitro microfluidic gut-on-chip is described herein that mimics the structure and at least one function of specific areas of the gastrointestinal system in vivo. In particular, a multicellular, layered, microfluidic culture is described, allowing for interactions between lamina propria-derived cells and gastrointestinal epithelial cells and endothelial cells. This in vitro microfluidic system can be used for modeling inflammatory gastrointestinal tissue, e.g., Crohn's disease, colitis and other inflammatory gastrointestinal disorders. These multicellular, layered microfluidic gut-on-chip further allow for comparisons between types of gastrointestinal tissues, e.g., small intestinal deuodejeum, small intestinal ileium, large intestinal colon, etc., and between disease states of gastrointestinal tissue, i.e. healthy, pre-disease and diseased areas.