Abstract: An exemplary surgical endocutter may include a staple holder; at least one feeder belt having two lateral edges, at least part of at least one feeder belt extending into the staple holder; and staples, wherein each said staple may include a first end frangibly affixed to a corresponding feeder belt, wherein each first end is affixed to the feeder belt at a location laterally spaced from the longitudinal centerline of the feeder belt, and a second free end; and wherein the staples form at least one row, each row including at least two said staples; wherein staples in least one row are staggered relative to said staples in at least one other row.

Abstract: An exemplary surgical method of treating tissue may include possessing a surgical tool that has at least one movable feeder belt that includes staples frangibly connected thereto, where at least one staple is oriented relative to the feeder belt in a direction angled relative to the transverse direction; placing the surgical tool adjacent to tissue; deforming at least one staple into tissue; frangibly separating at least one deformed staple from the feeder belt; advancing the feeder belt; and repeating the placing, deploying and separating. Another exemplary surgical method of treating tissue of a patient may include holding a cartridgeless surgical tool that includes staples; stapling tissue with staples in response to a single actuation of the surgical tool; and repeating the stapling at least once.

Abstract: A surgical endocutter may include an end effector, at least one feeder belt that extends at least partially into the end effector; and two or more staples, where each staple has a first end frangibly connected to a corresponding feeder belt and a second, free end, and where the staples form at least one row. The endocutter may be used to treat a patient by inserting the end effector into the body of a patient through an opening such as a trocar port, engaging tissue with the end effector, stapling tissue along two staple lines with the end effector; cutting tissue between the staple lines with the end effector, releasing the tissue from the end effector, and repeating the holding, stapling and engaging on tissue at a different location within the body of the patient without removing the end effector from within the body of the patient.

Abstract: An exemplary driverless surgical stapler may include a staple holder; staples positioned within that staple holder; and at least one wedge, where each wedge is slidable to directly contact at least one staple, where that contact causes deployment of each contacted staple. An exemplary surgical method may include providing a driverless surgical stapler that has a staple holder, staples positioned within the staple holder, and at least one wedge; and sliding at least one wedge relative to the staples to directly contact at least one staple.

Abstract: A surgical apparatus may include a feeder belt having two lateral edges, and a number of staples, where each staple includes a first end frangibly connected to the feeder belt and a second free end, where at least one staple is oriented relative to the feeder belt in a direction angled relative to the transverse direction, and where the staples form at least one row, each row including at least two staples. The feeder belt may be held by a surgical stapler. The surgical stapler may be utilized by placing that surgical stapler adjacent to tissue, deforming at least one staple into tissue, separating at least one deformed staple from the feeder belt, advancing the feeder belt, and repeating the placing, deploying and separating.

Abstract: A surgical method for treating a tissue structure having a wall and a lumen may include providing a substantially rigid anvil and a flexible tip affixed to and extending from the distal end of that anvil; making an incision in the wall of the tissue structure; inserting the flexible tip and at least a portion of the rigid anvil through the incision into the lumen of the tissue structure; and deforming at least one connector, introduced from outside the wall of the tissue structure, against the portion of the rigid anvil located within the lumen of the tissue structure.

Abstract: An exemplary surgical stapler may include a staple holder, staples positioned within the staple holder, and at least one structure slidable within the staple holder to contact directly at least one staple, where that direct contact deploys at least one staple from the staple holder. Another exemplary surgical stapler may include a staple holder, an anvil movably connected to the staple holder, staples positioned within the staple holder; and a sled slidable within the staple holder to contact directly at least one staple, where that direct contact urges at least one staple out of the staple holder and against the anvil.

Abstract: A method for closing a patent foramen ovale in the heart tissue of a patient may include percutaneously advancing a connector applicator to the patent foramen ovale, registering the connector applicator with the patent foramen ovale, deploying connectors into heart tissue to close the patent foramen ovale; and percutaneously removing the connector applicator from the heart. One or more anchors may be used to register the connector applicator with the patent foramen ovale. The connector applicator may include a driver having a longitudinal passage therein, where at least part of at least one connector is positioned within the passage.

Abstract: One example of surgical apparatus for treating tissue may include an effector including at least two jaws movable toward one another, where the effector holds and is configured to deploy a of clips in a clip application mode, and where the jaws are configured to deliver energy to coagulate tissue in a coagulation mode, where said effector is switchable between clip application mode and coagulation mode. Another example of surgical apparatus for treating tissue may include an effector holding clips, and two fingers movable toward one another to close the clips one at a time, where each finger is a different pole of a bipolar coagulator. An exemplary method for treating tissue with a surgical apparatus may include placing the surgical apparatus adjacent to tissue at a location, selecting one of a plurality of operational modes of the surgical apparatus, where the operational modes include clip application mode and coagulation mode, and actuating the surgical apparatus according to the selected operational mode.

Abstract: A tool for treating tissue in conjunction with one or more connectors may include an anvil against which at least one connector is urged, and a flexible tip extending from the distal end of said anvil. At least one connector may be held by a connector holder that is pivotally connected to the anvil. The anvil may be used to treat tissue by making an incision in the wall of the blood vessel, inserting the flexible tip and at least a portion of the anvil through the incision into the lumen of the blood vessel, and deforming at least one connector, introduced from outside the wall of the blood vessel, against the portion of the anvil that is located within the lumen of the blood vessel.

Abstract: An anastomosis system for connecting a graft vessel to a target vessel includes spaced-apart arms, and an anvil connected to those arms, where that anvil has a blunt distal end. The anvil is insertable into the target vessel. One or more connectors, such as staples, may be deployed from each arm to connect the graft vessel to the target vessel.

Abstract: An exemplary driverless surgical stapler may include a staple holder; staples positioned within that staple holder; and at least one wedge, where each wedge is slidable to directly contact at least one staple, where that contact causes deployment of each contacted staple. An exemplary surgical method may include providing a driverless surgical stapler that has a staple holder, staples positioned within the staple holder, and at least one wedge; and sliding at least one wedge relative to the staples to directly contact at least one staple.

Abstract: An integrated anastomosis tool may include an effector that both makes an opening in the wall of a target vessel and connects a graft vessel to the target vessel. The connection between the graft vessel and the target vessel may be compliant, and may be achieved by deploying a plurality of connectors such as staples into tissue. The effector may include a cutter assembly and a connection module that are independently actuatable. The cutter assembly and/or the connection module may be cable-actuated.

Abstract: An anastomosis tool includes a handle connected to a tissue effector that may be capable of being oriented in two or more positions relative to the handle. The tissue effector holds a graft vessel having at least one flap defined in at least one end thereof against the side of a target vessel. Actuation of a trigger or other mechanism on the handle causes the tissue effector to deploy one or more connectors into the flaps of the graft vessel and the side of the target vessel, thereby connecting the graft vessel to the target vessel.

Abstract: A method for closing an aneurysm in a blood vessel may utilize a staple having two or more tines, where those tines are oriented at least partially in the proximal direction. The method may include advancing the staple through the vasculature to a location within the aneurysm, plastically deforming the staple to a splayed configuration, penetrating at least one said tine of the staple in that splayed configuration into tissue in proximity to the neck of the aneurysm, and plastically deforming the staple to a closed configuration to close the aneurysm.

Abstract: A surgical tool may include a staple holding strip, and surgical staples frangibly connected to an edge of that staple holding strip.

Abstract: An implantable sterilization device may include a ring having an inner diameter, a core slidable through the inner diameter of the ring, and a tissue securing element, at least part of which is positioned between the ring and the core. A method of closing a fallopian tube may include providing a closure system including a handle, a flexible shaft connected to the handle, and a sterilization device detachably connected to the flexible shaft, inserting the flexible shaft into the lumen of the fallopian tube and advancing the flexible shaft into the lumen; compressing a portion of the wall of the fallopian tube with the sterilization device to secure the sterilization device relative to the fallopian tube, blocking the lumen of the fallopian tube with the sterilization device; and separating the sterilization device from the tube.

Abstract: One method for closing an opening in tissue may include providing a substantially continuous solid staple having a plurality of tines and a longitudinal centerline, plastically deforming the staple to a splayed configuration; penetrating at least one tine into tissue in proximity to the opening; and plastically deforming the staple to a closed configuration. Another method for closing an opening in tissue may include providing a staple having a plurality of tines; plastically deforming the staple to a splayed configuration by applying force in the distal direction against a proximal surface of the staple; penetrating at least one tine into tissue in proximity to the opening; and plastically deforming the staple from the splayed configuration to a closed configuration by applying force in the distal direction against a proximal surface of the staple.

Abstract: A method for anastomosing a first vessel to a second vessel may include connecting an end of the first vessel to the side of the second vessel and creating an opening in the wall of the second vessel from within the lumen of the second vessel, where that opening allows fluid communication between the lumen of the first vessel and the lumen of the second vessel.

Abstract: An exemplary medical apparatus insertable into the vasculature of a patient at an insertion point for treating a defect in the heart, may include an elongated, flexible driver sufficient in length to extend from the insertion point to the defect in the heart; and a staple frangibly attached to the distal end of the driver. Another exemplary medical apparatus may include a catheter sufficient in length to extend from the insertion point to the patent foramen ovale; a housing attached to the distal end of the catheter; a driver extending into the housing; and a staple frangibly attached to the driver.