Abstract: A data cable contains a cable core having a plurality of core pairs. Each of the core pairs are composed of two cores directly surrounded by a pair shielding. The pair shielding has a conductive exterior surrounding a core pair and being oriented outward. An overall shield surrounds the cable core and lies on the conductive exterior of the pair shielding and is thereby electrically connected to the cable core.

Abstract: A method monitors a line for changed ambient conditions. The line has a measuring line with a predetermined length and a measuring conductor surrounded by insulation having a known dielectric constant. In the method, an analog signal having a predetermined frequency is generated, the signal is divided into a reference signal and an operating signal, the operating signal is fed into the measuring conductor, a return signal obtained from the operating signal is combined with the reference signal and by a phase shift between the reference signal and the return signal, a measure is determined for the changed condition, particularly for a temperature change.

Abstract: In a contact connecting of preferably a number of shielded conductor pairs to a board in particular of a plug for high-speed data connections, the board is formed of multiple layers and contains a conductor path tier and a ground tier. A ground contact zone of the ground tier projects, in a tongue-like manner, towards the connected conductor pairs. In the region of the ground contact zone, the individual conductor pairs are pressed in contact against the corresponding pair shielding thereof. To this end, in particular a clamping element is provided that is also used to achieve the shield contacting.

Abstract: A data cable for high-speed data transmissions includes at least one wire pair formed of wires extending in a longitudinal direction and being surrounded by a shielding foil to form a pair shielding. A dielectric intermediate film or foil having a varying lay length is spun around the wire pair between the shielding foil and the wire pair, in order to effectively avoid a damping peak at high transmission frequencies.

Abstract: A data cable for high-speed data transmissions includes at least one wire pair formed of wires extending in a longitudinal direction and being surrounded by a shielding foil to form a pair shielding. A dielectric intermediate film or foil having a varying lay length is spun around the wire pair between the shielding foil and the wire pair, in order to effectively avoid a damping peak at high transmission frequencies.

Abstract: A data cable for high-speed data transmission at signal frequencies of >10 GHz includes at least one core pair which is surrounded by a film-shaped pair shield having an inner shielding film and an outer shielding film which, are in electrical contact with one another and in which the inner shielding film is wound around the core pair. By virtue of this measure, an undesired resonance effect is avoided which, in previously wound pair shields, has not allowed use for relatively high signal frequencies. At the same time, an undesired common-mode signal, which would occur in the case of a longitudinally folded shielding film, is thus suppressed.

Abstract: A device, in particular a pre-assembled transmission cable, is used to transmit differential data signals in a high-speed data connection. The device contains a circuit board with a conductor pair with two signal conductors for transmitting the differential data signal. An output line which is insulated from the conductor pair is paired with the conductor pair, the output line running parallel to the signal conductors in a non-interrupted manner and additionally being connected to a measuring conductor via at least one damping element. By virtue of the configuration, an undesired common-mode signal component is at least partly coupled into the output line, where the signal component is absorbed during operation.

Abstract: In a contact connecting of preferably a number of shielded conductor pairs to a board in particular of a plug for high-speed data connections, the board is formed of multiple layers and contains a conductor path tier and a ground tier. A ground contact zone of the ground tier projects, in a tongue-like manner, towards the connected conductor pairs. In the region of the ground contact zone, the individual conductor pairs are pressed in contact against the corresponding pair shielding thereof. To this end, in particular a clamping element is provided that is also used to achieve the shield contacting.

Abstract: A signal cable, namely a coaxial cable or a balanced cable, has at least one signal conductor for transmitting high frequency signals, in particular also in the gigahertz range, while having an acceptable return loss. It is provided optionally or in combination that the signal conductor is embodied as a stranded conductor with a varying lay length or that the signal cable is a balanced cable having signal conductors that are mutually twisted with a varying lay length.

Abstract: The present invention provides novel imidazo[1,2-a]pyridine compounds that are useful in therapy of diseases and disorders. The novel compounds inhibit the activation of Hypoxia Inducible Factor (HIF)-mediated transcription and signaling under hypoxic conditions. In one aspect, the compounds of the present invention are useful for the preparation of a medicament for the treatment or prevention of a disease or disorder selected from the group consisting of an inflammatory disease, a hyperproliferative disease or disorder, a hypoxia-related pathology and a disease characterized by excessive vascularization.

Abstract: The present invention provides antineoplastic peptides of formula I, I R1R2N-CHX-CO-A-B-D-E-(G)S-K wherein R1, R2, X, A, B, D, E, G, K and s have the meanings stated in the description. The compounds have antineoplastic activity.

Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L??(I), and acid salts thereof, wherein A, B, D, E, F, G and K are ?-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a ?-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.

Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L??(I), and acid salts thereof, wherein A, B, D, E, F, G and K are ?-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a ?-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.

Abstract: The present invention provides compounds of formula (I), wherein R1 is a monocyclic 5- or 6-membered heteroaryl; R4 is phenyl or monocyclic 5- or 6-membered heteroaryl; and the other substituents as defined in the claims, that inhibit cell and cell division and that inhibit the activation of Hypoxia Inducible Factor (HIF)—mediated transcription and signaling under hypoxic conditions. In one aspect, the compounds of the present invention are useful for the preparation of a medicament for the treatment or prevention of a disease or disorder selected from the group consisting of an inflammatory disease, a hyperproliferative disease or disorder, a hypoxia-related pathology and a disease characterized by excessive vascularisation. Also provided is a pharmaceutical composition, comprising a compound of the invention and a second therapeutic agent or radiation, useful for the treatment or prevention of the mentioned diseases or disorders.

Abstract: The present invention provides novel compounds that inhibit cell proliferation and cell division and that inhibit the activation of Hypoxia Inducible Factor (HIF)-mediated transcription and signaling under hypoxic conditions. In one aspect, the compounds of the present invention are useful for the preparation of a medicament for the treatment or prevention of a disease or disorder selected from the group consisting of an inflammatory disease, a hyperproliferative disease or disorder, a hypoxia-related pathology and a disease characterized by excessive vascularisation. Also provided is a pharmaceutical composition comprising a compound of the invention and a second therapeutic agent or radiation useful for the treatment or prevention of the mentioned diseases or disorders. In a first aspect the present invention relates to a compound having a structure according to formula (I).

Abstract: The present invention provides antineoplastic peptides of formula I, R1R2N-CHX-CO-A-B-D-E-(G)S-K?I wherein R1, R2, X, A, B, D, G, K and s have the meanings stated in the description. The compounds have antineoplastic activity.

Abstract: The present invention provides antineoplastic peptides of formula I, R1R2N—CHX—CO—A—B-D-E-(G)s-K wherein R1, R2, X, A, B, D, E, G, K and s have the meanings stated in the description. The compounds have antineoplastic activity.

Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L??(I), and acid salts thereof, wherein A, B, D, E, F, G and K are ?-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a ?-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.

Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L ??(I), and acid salts thereof, wherein A, B, D, E, F, G and K are ?-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a ?-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.

Abstract: A data transmission cable (2) comprises at least one pair of wires (4) comprising two wires (6) lying parallel to each other, each with an electrical conductor (8) surrounded by an insulation (10). The pair of wires (4) is sheathed over its length by a foil (12) with an electrically conducting inner side (14) and an electrically insulating outer side (16). To improve the electrical properties of the data transmission cable (2), the foil (12) has a longitudinal fold (18), so that the inner side (14) is directed outward, an additional wire (20), which contacts the inner side (14) made to face outward, being laid on the foil (12).