Patents by Inventor Bernd Kuhn

Bernd Kuhn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050288308
    Abstract: Compounds of the formula (I): as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5 have the significance given in claim 1 can be used in the form of pharmaceutical compositions.
    Type: Application
    Filed: June 27, 2005
    Publication date: December 29, 2005
    Inventors: Kurt Amrien, Daniel Hunziker, Bernd Kuhn, Alexander Mayweg, Werner Neidhart
  • Publication number: 20050245589
    Abstract: The invention relates to compounds of the formula I: wherein one of R5, R6 and R7 is and X1, X2, R1 to R15 and n are as defined in the description, and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR ? and/or PPAR? agonists.
    Type: Application
    Filed: April 26, 2005
    Publication date: November 3, 2005
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Matthew Wright
  • Publication number: 20050245515
    Abstract: The invention relates to compounds of formula (I): and pharmaceutically acceptable salts and pharmaceutically acceptable esters thereof, wherein R1, R2, R3, R4, R5, R6, A, m, n and p are defined as in claim 1. These compounds can be used as pharmaceutical compositions for the treatment of, for example, diabetes.
    Type: Application
    Filed: April 27, 2005
    Publication date: November 3, 2005
    Inventors: Henrietta Dehmlow, Bernd Kuhn, Narendra Panday, Hasane Ratni, Tanja Schulz-Gasch, Matthew Wright
  • Publication number: 20050215577
    Abstract: The present invention relates to compounds of the formula (I) wherein R1, R2, R3, R4, R5, X1, X2, X3, X4, n, and k are defined in the description and claims, and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for in the treatment and prophylaxis of diseases which are modulated by LXR? and/or LXR? agonists, including increased lipid and cholesterol levels, particularly low HDL-cholesterol, high LDL-cholesterol, atherosclerotic diseases, diabetes, particularly non-insulin dependent diabetes mellitus, metabolic syndrome, dyslipidemia, Alzheimer's disease, sepsis, inflammatory diseases such as colitis, pancreatitis, cholestasis/fibrosis of the liver, and diseases that have an inflammatory component such as Alzheimer's disease or impaired/improvable cognitive function.
    Type: Application
    Filed: March 23, 2005
    Publication date: September 29, 2005
    Inventors: Henrietta Dehmlow, Bernd Kuhn, Raffaello Masciadri, Narendra Panday, Hasane Ratni, Matthew Wright
  • Publication number: 20050203160
    Abstract: This invention relates to compounds of the formula I: wherein one of R6, R7 and R8 is and R1 to R15 and n are as defined in the description, and all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR ? and/or PPAR? agonists.
    Type: Application
    Filed: March 8, 2005
    Publication date: September 15, 2005
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Matthew Wright
  • Publication number: 20050186463
    Abstract: A sealing structure in a fuel cell and/or an electrolyzer (particularly a solid-oxide fuel cell and/or a solid-oxide electrolyzer) is arranged between neighboring separator plates of a cell stack. The sealing structure is constructed in at least two layers, including at least one insulating layer and at least one sealing layer.
    Type: Application
    Filed: March 22, 2005
    Publication date: August 25, 2005
    Applicant: Bayerische Motoren Werke AG
    Inventors: Olav Finkenwirth, Bernd Kuhn, Hans-Rainer Zerfass
  • Publication number: 20050175884
    Abstract: A fuel cell includes a cathode-electrolyte-anode unit, and a perforated foil structure distributes fuel gas over an electrode surface thereof. Longitudinal axes of at least some of the holes forming perforations in the foil are inclined differently relative to the foil surface such that, near a fuel gas feed, the outlet openings of the holes facing the electrode are oriented at least slightly toward the area of the fuel gas outlet from the fuel cell. Near a fuel gas outlet, the inlet openings of the holes facing the electrode are oriented at least slightly to the area of the fuel gas feed. However, holes whose inlet openings facing away from the electrode are oriented toward the fuel gas feed, and holes whose outlet openings facing away from the electrode are oriented toward the fuel gas outlet, may also be arranged alternately side-by-side.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 11, 2005
    Applicant: Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Maximilian Danzer, Franz-Josef Wetzel, Xiaofeng Yan, Thomas Hoefler, Bernd Kuhn, Andreas Stoermer, Olav Finkenwirth
  • Patent number: 6916484
    Abstract: The invention relates to an aqueous pharmaceutical composition containing moxifloxacin and less than 10 ppb iron.
    Type: Grant
    Filed: July 25, 2000
    Date of Patent: July 12, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd Kühn, Hans-Friedrich Mahler, Michael Eisele
  • Publication number: 20050142426
    Abstract: A fuel cell stack comprises several mutually stacked fuel cells, each of which has a cathode-electrolyte-anode unit, and a perforated foil for distributing a fuel gas over a first electrode surface. The foil carries the cathode-electrolyte-anode unit and is assembled with a further structure to form an enclosure having a cavity through which fuel gas flows to the first electrode. Opposite the cathode-electrolyte-anode unit, each enclosure has a distribution configuration for distributing air-oxygen over the surface of the second electrode of an adjacent enclosure, so that a cathode-electrolyte-anode unit and a distribution configuration are situated between the foil and the further structure of adjacent enclosures in the stack. In addition, the stack contains at least one bracing enclosure whose walls have an impermeable construction and which is filled with a material expands when heated.
    Type: Application
    Filed: February 24, 2005
    Publication date: June 30, 2005
    Applicant: Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Maximilian Danzer, Franz Wetzel, Xiaofeng Yan, Thomas Hoefler, Bernd Kuhn, Andreas Stoermer, Olav Finkenwirth
  • Patent number: 6890947
    Abstract: Compounds of formula I are provided as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R8, A, A1 and n have the significance indicated in the specification.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: May 10, 2005
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alfred Binggeli, Beat Wirz, Uwe Grether, Hans Hilpert, Roland Humm, Hans Iding, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr
  • Publication number: 20050096353
    Abstract: This invention relates to compounds of the formula wherein one of R6, R7 and R8 is and X, Y1 to Y4, R1 to R14 and n are as defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.
    Type: Application
    Filed: October 29, 2004
    Publication date: May 5, 2005
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Matthew Blake Wright
  • Publication number: 20050096337
    Abstract: This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.
    Type: Application
    Filed: October 29, 2004
    Publication date: May 5, 2005
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Matthew Wright
  • Publication number: 20050096336
    Abstract: There are presented compounds of the formula wherein R6 and R7 is R4 and R5 or R5 and R6 together with the carbon atoms to which they are attached, form a ring as defined in the description and X1, X2, Y1 to Y4, R1 to R13 and n are as specified in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.
    Type: Application
    Filed: October 29, 2004
    Publication date: May 5, 2005
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Matthew Wright
  • Publication number: 20050004187
    Abstract: This invention relates to compounds of the formula wherein one of R6, R7 or R8 is and all enantiomers and pharmaceutically acceptable salts and/or esters thereof as well as pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.
    Type: Application
    Filed: June 28, 2004
    Publication date: January 6, 2005
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Matthew Wright
  • Publication number: 20040259902
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: June 17, 2004
    Publication date: December 23, 2004
    Inventors: Markus Boehringer, Bernd Kuhn, Thomas Luebbers, Patrizio Mattei, Robert Narquizian, Hans Peter Wessel
  • Publication number: 20040259903
    Abstract: The present invention provides compounds of formula (I) 1
    Type: Application
    Filed: June 17, 2004
    Publication date: December 23, 2004
    Inventors: Markus Boehringer, Bernd Kuhn, Patrizio Mattei, Robert Narquizian
  • Publication number: 20040248951
    Abstract: This invention relates to compounds of the formula 1
    Type: Application
    Filed: June 1, 2004
    Publication date: December 9, 2004
    Inventors: Jean Ackermann, Johannes Aebi, Alfred Binggeli, Uwe Grether, Georges Hirth, Bernd Kuhn, Hans-Peter Maerki, Markus Meyer, Peter Mohr, Mathew Blake Wright
  • Publication number: 20040219417
    Abstract: A sealing structure in a fuel cell and/or an electrolyzer (particularly a solid-oxide fuel cell and/or a solid-oxide electrolyzer) is arranged between neighboring separator plates of a cell stack. The sealing structure is constructed in at least two layers, including at least one insulating layer and at least one sealing layer.
    Type: Application
    Filed: January 21, 2004
    Publication date: November 4, 2004
    Applicant: Bayerische Motoren Aktiengesellschaft
    Inventors: Olav Finkenwirth, Bernd Kuhn
  • Publication number: 20040200686
    Abstract: A housing arrangement can be connected to a flywheel for rotation in common around an axis of rotation, and a pressure element is connected to the housing arrangement for rotation in common around the axis of rotation but is able to shift in the axial direction. A release spring arrangement includes at least one spring element which acts on the pressure element and is supported against the flywheel after the housing arrangement has been attached to the flywheel. Each spring element is held in place on the pressure element by means of a fastening element.
    Type: Application
    Filed: February 26, 2004
    Publication date: October 14, 2004
    Applicant: ZF Sachs AG
    Inventors: Alfred Schauer, Bernd Kuhn, Thomas Schubert, Jurgen Pfeifer
  • Publication number: 20040180005
    Abstract: A method for the production of nanodispersions, in which at least two metered partial streams are brought together in such a way that they are subject to thorough mixing caused by turbulence. The partial streams have a flow rate in the range from 0.1 to 500 ml/h and the mixed stream has an overall flow rate in the range from 1 ml/h to 500 ml/h. The turbulent mixing leads to the formation of a disperse phase in a continuous phase with a dispersity of 0.1 to 5000 nm. Another object of the invention is a method for the in-situ formulation of a pharmaceutical dispersion, with in-line application of the pharmaceutical dispersion.
    Type: Application
    Filed: November 19, 2003
    Publication date: September 16, 2004
    Inventors: Kai Christian Jurgens, Bernd Kuhn