Patents by Inventor Bernd Stahl

Bernd Stahl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110112280
    Abstract: The present invention relates to the use of a modulator of a polypeptide having or comprising an amino acid sequence as disclosed herein or of a functional fragment or derivative thereof or of a polynucleotide encoding said polypeptide or fragment or derivative for the preparation of a pharmaceutical composition for preventing, alleviating or treating diseases or conditions associated with the degeneration or injury of vertebrate nervous tissue, associated with seizures or associated with angiogenic disorders or disorders of the cardiovascular system.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 12, 2011
    Inventors: Bernhard K. Mueller, Philippe P. Monnier, Paolo Macchi, Friedrich Bonhoeffer, Bernd Stahl, Matthias Mann, Jens S. Andersen
  • Patent number: 7939118
    Abstract: An oligosaccharide mixture based on oligosaccharides from one or several animal milks composed of two or more monosaccharide units. The oligosaccharide mixture comprises at least two oligosaccharide fractions which are each composed of at least two different oligosaccharides. Lactose does not pertain thereto and the total spectrum of the oligosaccharides in the oligosaccharide mixture differs from those present in animal milk or animal milks, wherefrom the oligosaccharide fractions are extracted and that a) if the oligosaccharides are extracted from only one animal milk, the proportion of neutral oligosaccharides to acidic oligosaccharides is 90-60:10-40 weight %, or b) if the oligosaccharides are extracted from at least two animal milks, the oligosaccharides extracted from two different animal milks each make up 10 weight % of the total amount of oligosaccharides present in the oligosaccharide mixture. The oligosaccharide mixture approximates human milk with respect to its positive properties.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: May 10, 2011
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Günther Böhm, Berndt Finke, Gilda Georgi, Jürgen Jelinek, Joachim J. Schmitt
  • Publication number: 20110098246
    Abstract: The present invention relates to the use of nutritional compositions comprising non-digestible oligosaccharides for preventing corticoid administration, particularly to infants.
    Type: Application
    Filed: June 5, 2009
    Publication date: April 28, 2011
    Inventors: Bernd Stahl, Jürgen Jelinek, Günther Boehm
  • Publication number: 20110086814
    Abstract: The present invention concerns the use of uronic acid saccharide for preventing growth of Enterobacter sakazakii.
    Type: Application
    Filed: June 5, 2009
    Publication date: April 14, 2011
    Applicant: N.V. NUTRICIA
    Inventors: Bernd Stahl, Matthias Fischer
  • Patent number: 7919479
    Abstract: Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells. Said preparation contains at least one carbohydrate having an uronic acid unit on one of the ends thereof. 10 to 100% of the present, terminal uronic acid units pertaining to the carbohydrates are provided with a double bond that is especially situated between the C4 and C5 atom.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: April 5, 2011
    Assignee: N. V. Nutricia
    Inventors: Bernd Stahl, Gunther Boehm
  • Publication number: 20100330040
    Abstract: Nutritional compositions with health benefits comprising bacterial strains and galactooligosaccharides are disclosed.
    Type: Application
    Filed: November 20, 2008
    Publication date: December 30, 2010
    Inventors: Jan Knol, Bernd Stahl
  • Patent number: 7858595
    Abstract: Neutral straight-chain or branched oligosaccharides for preventing the invasion and infection of mammal cells by pathogens and for fighting diseases caused by such pathogens are disclosed. Food, dietetic products and pharmaceutical agents containing oligosaccharides consist of a base unit of formula (I), and between 0 and 19 other units of formula (II), which are linked directly or indirectly to the base unit. Gal represents a galactose monosaccharide unit; Glc represents a glucose monosaccharide unit; HexNAc rpresents an N-acetylated galactosamine or glucosamine monosaccharide unit (GalNAc or GlcNAc); R independently represent a ? 1-3 or ? 1-6 glycosidic link to HexNAc monosaccharide of the next [Gal-HexNAc] unit (II), and on a terminal [Gal-HexNAc] unit, or R are not present; and a terminal [Gal-HexNAc] unit, wherein R represent a deoxyhexose radical, can have another deoxyhexose radical on the HexNAc monosaccharide unit.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: December 28, 2010
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Berndt Finke, Joachim Schmitt, Werner Goebel, Jörg Slaghuis
  • Publication number: 20100234286
    Abstract: The present invention relates to a method and a composition for feeding low birthweight infants (LBW infants), very low birthweight infants (VLBW infants), extremely low birthweight infants (ELBW infants) and preterm infants for improving oral tolerance.
    Type: Application
    Filed: March 23, 2007
    Publication date: September 16, 2010
    Applicant: N.V. NUTRICIA
    Inventors: Gilda Georgi, Bernd Stahl, Günther Boehm
  • Publication number: 20100216740
    Abstract: Cereal-based semi-liquid and/or semi-solid compositions suitable for supporting the transition period wherein the infant changes from a diet consisting of breast milk or liquid infant formula to solid adult foods, comprising uronic acid carbohydrates with a degree of polymerisation (DP) between 10 and 300 and also uses thereof are disclosed.
    Type: Application
    Filed: March 21, 2008
    Publication date: August 26, 2010
    Applicant: N.V. NUTRICIA
    Inventors: Bernd Stahl, Martine Sandra Alles, Brigitte Antonia Maria Borgmann
  • Patent number: 7759324
    Abstract: Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells. Said preparation contains at least one carbohydrate having an uronic acid unit on one of the ends thereof. 10 to 100% of the present, terminal uronic acid units pertaining to the carbohydrates are provided with a double bond that is especially situated between the C4 and C5 atom.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: July 20, 2010
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Gunther Boehm
  • Publication number: 20100167982
    Abstract: The invention concerns a method for stimulating intestinal barrier integrity in a patient infected with HIV by administering to said patient composition comprising: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (ARA), and at least two distinct oligosaccharides.
    Type: Application
    Filed: December 29, 2009
    Publication date: July 1, 2010
    Inventors: Eric Alexander Franciscus van Tol, Linette Eustachia Maria Willemsen, Marleen Antoinette Koetsier, Christopher Beermann, Bernd Stahl
  • Publication number: 20100136134
    Abstract: A nutritional or pharmaceutical composition containing a fat component, a protein component and a carbohydrate component and comprising whey and casein. The composition has a weight ratio of casein to whey is 1:1 to 1:2.4 and that the composition contains: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids. The long chain polyunsaturated fatty acid being docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. The composition reduces—among others—the risks attached to feeding whey dominant infant formula.
    Type: Application
    Filed: August 19, 2005
    Publication date: June 3, 2010
    Applicant: N.V. Nutricia
    Inventors: Günther Boehm, Christopher Beermann, Bernd Stahl, Laura M'rabet, Johan Garssen
  • Publication number: 20100063002
    Abstract: The present invention concerns a therapy aimed at language and/or social skills in infants through administration of components stimulating the development of a healthy intestinal flora.
    Type: Application
    Filed: March 13, 2007
    Publication date: March 11, 2010
    Inventors: Bernd Stahl, Jan Knol
  • Publication number: 20100035828
    Abstract: The present invention relates to methods and nutritional compositions for stimulating the immune system, particularly in subjects with an impaired immune system such as 5 infants, said method comprising administering a composition comprising sheep milk and/or short chain oligosaccharides.
    Type: Application
    Filed: March 21, 2007
    Publication date: February 11, 2010
    Inventors: Laura M'Rabet, Antonie Van Baalen, Bernd Stahl, Arjan Paul Vos, Thomas Hubertus Martinus Snoeren
  • Patent number: 7655784
    Abstract: The invention relates to novel enzymes, which transfer sialic acid from a donor molecule onto an acceptor molecule (trans-sialidases). The enzymes are isolated from the protozoan Trypanosoma congolense.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: February 2, 2010
    Assignee: N.V. Nutricia
    Inventors: Joachim Schmitt, Gunter Boehm, Bernd Stahl, Roland Schauer, Evelin Tiralongo, Silke Schrader
  • Publication number: 20100016214
    Abstract: A carbohydrate mixture for dietetic foods and pharmaceuticals containing several carbohydrates is provided according to the present invention. Said carbohydrate mixture is characterized in that they contain or consist of two different, substantially soluble carbohydrate components A and B, which remain undigested in the gastrointestinal tract and enter the large intestine without being resorbed, that said carbohydrate component A is composed of at least one monosaccharide or of at least one oligosaccharide (disaccharide to hexasaccharide) or of a mixture of two or more of these saccharides, that the carbohydrate component B is composed of a polysaccharide (from heptasaccharide onwards) or of a mixture of two or more polysaccharides, that the carbohydrate component A=5 to 95 wt-% and the carbohydrate component B=5 to 95 wt-% of the sum of the carbohydrate components A+B (=100 wt-%), and that at least 80 wt-% of the carbohydrates/saccharides of the carbohydrate components A and B have a prebiotic effect.
    Type: Application
    Filed: September 23, 2009
    Publication date: January 21, 2010
    Inventors: Gunther SAWATZKI, Bernd Stahl
  • Publication number: 20090305362
    Abstract: The present invention provides processes for the manufacture of uronic acid oligosaccharides using extrusion. The uronic acid polymers are extruded with an enzyme, under basic conditions (pH>9) and/or under high shear.
    Type: Application
    Filed: July 19, 2006
    Publication date: December 10, 2009
    Applicant: N.V Nutricia
    Inventors: Bernd Stahl, Ton A. Van Baalen
  • Publication number: 20090305996
    Abstract: A food or supplement for pregnant women comprising water soluble, non-digestible saccharides is described. The composition is used to improve the flora and/or immune system of the pregnant women, to improve the immune system of the infant and to improve the intestinal flora of the infant after birth.
    Type: Application
    Filed: March 9, 2007
    Publication date: December 10, 2009
    Inventors: Christopher Beermann, Jan Knol, Martine Sandra Alles, Bernd Stahl, Günther Boehm
  • Patent number: 7601364
    Abstract: A carbohydrate mixture for dietetic foods and pharmaceuticals containing several carbohydrates is provided. The carbohydrate mixture comprises two different, substantially soluble carbohydrate components A and B, which remain undigested in the gastrointestinal tract and enter the large intestine without being resorbed. Component A comprises at least one monosaccharide, at least one oligosaccharide (disaccharide to hexasaccharide), or a mixture thereof. Component B comprises a polysaccharide or a mixture of two or more polysaccharides. Component A constitutes 5 to 95 wt-% and Component B constitutes 5 to 95 wt-% of the sum of the Components; and at least 80 wt-% of the carbohydrates/saccharides of Components A and B have a prebiotic effect. The inventive carbohydrate mixture exhibits not only a nutritive effect, but also stimulates health-promoting microorganisms present in the natural flora of the large intestine.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: October 13, 2009
    Assignee: N.V. Nutricia
    Inventors: Gunther Sawatzki, Bernd Stahl
  • Publication number: 20090221486
    Abstract: The present invention provides the use of a composition comprising uronic acid oligosaccharide for the manufacture of a composition for enteral administration to an infant delivered via caesarean section.
    Type: Application
    Filed: October 6, 2006
    Publication date: September 3, 2009
    Inventors: Joachim Schmitt, Bernd Stahl, Jan Knol