Patents by Inventor Bernd Stahl

Bernd Stahl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090220639
    Abstract: The present invention provides the use of a composition comprising non-digestible oligosaccharide for the manufacture of a composition for enteral administration to an infant delivered via caesarean section.
    Type: Application
    Filed: October 6, 2006
    Publication date: September 3, 2009
    Applicant: N.V. NUTRICIA
    Inventors: Joachim Schmitt, Bernd Stahl, Jan Knol
  • Publication number: 20090162323
    Abstract: The present invention relates to methods for feeding and to compositions to be administered to infants delivered via caesarian section and in particular to the use of a) at least two different microorganisms; or b) at least one microorganism and at least one indigestible oligosaccharide; or c) at least two different Bifidobacteria species, subspecies or strains for the manufacture of a composition for enteral administration to an infant delivered via caesarean section. Thereby it is possible to stimulate the healthy development of the intestinal flora of said infants.
    Type: Application
    Filed: October 20, 2006
    Publication date: June 25, 2009
    Applicant: N.V. Nutricia
    Inventors: Günther Boehm, Bernd Stahl, Jan Knol
  • Publication number: 20090156550
    Abstract: The present invention relates to the use of oligosaccharide mixtures for the treatment and/or prevention of infections, in particular for reducing the severity of childhood infection or the treatment and/or prevention of childhood infection.
    Type: Application
    Filed: December 6, 2005
    Publication date: June 18, 2009
    Inventors: Belinda Potappel-Van 'T Land, Johan Garssen, Gunther Boehm, Bernd Stahl
  • Patent number: 7498318
    Abstract: Provided is a carbohydrate mixture comprising at least one modified carbohydrate from a base body and a carbohydrate residue coupled therewith. The base body concerned is either a digestible glucose-containing carbohydrate in the form of a digestible glucan or a non-digestible reserve carbohydrate, skeletal carbohydrate or a low-molecular component thereof. By coupling the base body with a carbohydrate residue, the glucose release from the inventive carbohydrate mixture is reduced by at least 10%, determined in an in-vivo digestion system on the basis of pancreatine and compared with a carbohydrate mixture containing the same amount by weight of non-modified carbohydrates. By means of the inventive carbohydrate mixture, the postprandial blood glucose concentration after eating can be moderated. The glucose can thus be metabolized by diabetics in spite of the existing lack of insulin. The inventive carbohydrate mixtures can be used in food for diabetics and in pharmaceuticals.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: March 3, 2009
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Michael Kliem, Sandra Farwer, Gunther Sawatzki, Gunther Boehm
  • Patent number: 7445904
    Abstract: The present invention relates to in vitro and in vivo assays for the identification of agents that are useful in the treatment of neurodegenerative diseases that are associated with defects in protein folding. The present further relates to in vitro and in vivo assays for the identification of agents that contribute to the neurodegenerative processes which occur in these diseases. The present invention also relates to in vitro and in vivo models of neurodegenerative diseases. These assays and models will be useful in further understanding the pathogenesis of various neurodegenerative diseases in which defects in protein folding have been implicated, in identifying additional endogenous or environmental factors that contribute to the etiologies of these diseases, and in developing effective therapies for the prevention and/or treatment of these diseases.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: November 4, 2008
    Inventors: Thomas C Südhof, Bernd Stahl, Soenke Tobaben
  • Publication number: 20080269330
    Abstract: The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
    Type: Application
    Filed: November 11, 2005
    Publication date: October 30, 2008
    Applicant: N.V. Nutricia
    Inventors: Bernd Stahl, Gunther Boehm, Christopher Beermann, Johan Garssen
  • Publication number: 20080207559
    Abstract: A carbohydrate mixture for dietetic foods and pharmaceuticals containing several carbohydrates is provided according to the present invention. Said carbohydrate mixture is characterized in that they contain or consist of two different, substantially soluble carbohydrate components A and B, which remain undigested in the gastrointestinal tract and enter the large intestine without being resorbed, that said carbohydrate component A is composed of at least one monosaccharide or of at least one oligosaccharide (disaccharide to hexasaccharide) or of a mixture of two or more of these saccharides, that the carbohydrate component B is composed of a polysaccharide (from heptasaccharide onwards) or of a mixture of two or more polysaccharides, that the carbohydrate component A=5 to 95 wt-% and the carbohydrate component B=5 to 95 wt-% of the sum of the carbohydrate components A+B (=100 wt-%), and that at least 80 wt-% of the carbohydrates/saccharides of the carbohydrate components A and B have a prebiotic effect.
    Type: Application
    Filed: April 30, 2008
    Publication date: August 28, 2008
    Applicant: N.V. Nutricia
    Inventors: Gunther Sawatzki, Bernd Stahl
  • Publication number: 20080199446
    Abstract: The present invention relates to compositions containing probiotic bacteria and uronic acid oligosaccharides. The compositions can suitably be used as infant nutrition and advantageously reduce the incidence of infection.
    Type: Application
    Filed: April 18, 2006
    Publication date: August 21, 2008
    Inventors: Adrianus Johannes Maria Vriesema, Jan Knol, Bernd Stahl
  • Publication number: 20080193627
    Abstract: The present invention relates to a process for spray drying uronic acid oligosaccharides and to a powder compositions thus obtained. Typically the powder composition comprises between 25 and 100 wt. % uronic acid oligosaccharide with a DP between 2 and 50 based on total weight of uronic acid, with and an average particle size between 20 ?m and 100 ?m.
    Type: Application
    Filed: April 21, 2006
    Publication date: August 14, 2008
    Inventors: Martin Van Eert, Bernd Stahl, Antonie Van Baalen
  • Publication number: 20080124323
    Abstract: The present invention provides a method and composition for the treatment and/or prevention of respiratory tract infection and/or respiratory tract infection disease, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and at least 5 wt. % digestible galactose saccharide.
    Type: Application
    Filed: August 24, 2005
    Publication date: May 29, 2008
    Inventors: Gunther Boehm, Laura M'Rabet, Bernd Stahl, Johan Garssen
  • Publication number: 20080125346
    Abstract: The present invention relates to a nutritional composition containing protein, fat and carbohydrate; and a. a nucleotide component selected from the group consisting of nucleic acid, nucleic acid derivatives, nucleotides, nucleoside polyphosphates, polynucleotides, nucleosides, ribose, desoxyribose, and dinucleosidpolyphosphates (NpxN); and b. a non-proteinaceous negatively charged, glycan or glycoconjugate component with a molecular weight between 200 and 20.000 dalton. The present nutritional composition is particularly suited for feeding infants as it mimics the protective effects of human milk, in particular against allergies and infections.
    Type: Application
    Filed: August 22, 2005
    Publication date: May 29, 2008
    Inventors: Christopher Beermann, Gunther Boehm, Bernd Stahl
  • Publication number: 20080096794
    Abstract: The invention relates to the use of a peptide mixture comprising peptides with a molecular weight from 1000 to 5000 Daltons for the prevention and/or treatment of tumour diseases, of diseases which are associated with a development disorder of the immune system, of diseases of the immune system, of autoimmune reactions, of allergies and of inflammation in man, a protein component which contains such a peptide mixture and a formula food containing this peptide mixture. The peptides are preferably obtained from non-human proteins suitable for nutritional purposes, in particular by the enzymatic or hydrolytic cleavage of these proteins.
    Type: Application
    Filed: August 12, 2005
    Publication date: April 24, 2008
    Inventors: Gunther Boehm, Christopher Beermann, Bernd Stahl, Gilda Georgi, Joachim Schmitt, Nadine Bock, Sorge Kelm
  • Publication number: 20080015166
    Abstract: The invention concerns a method for stimulating intestinal barrier integrity in a patient infected with HIV by administering to said patient composition comprising: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (ARA), and at least two distinct oligosaccharides.
    Type: Application
    Filed: June 22, 2005
    Publication date: January 17, 2008
    Inventors: Eric Alexander van Tol, Linette Eustachia Willemsen, Marleen Koetsier, Christopher Beermann, Bernd Stahl
  • Publication number: 20070248649
    Abstract: A carbohydrate mixture for dietetic foods and pharmaceuticals containing several carbohydrates is provided according to the present invention. Said carbohydrate mixture is characterized in that they contain or consist of two different, substantially soluble carbohydrate components A and B, which remain undigested in the gastrointestinal tract and enter the large intestine without being resorbed, that said carbohydrate component A is composed of at least one monosaccharide or of at least one oligosaccharide (disaccharide to hexasaccharide) or of a mixture of two or more of these saccharides, that the carbohydrate component B is composed of a polysaccharide (from heptasaccharide onwards) or of a mixture of two or more polysaccharides, that the carbohydrate component A=5 to 95 wt-% and the carbohydrate component B=5 to 95 wt-% of the sum of the carbohydrate components A+B (=100 wt-%), and that at least 80 wt-% of the carbohydrates/saccharides of the carbohydrate components A and B have a prebiotic effect.
    Type: Application
    Filed: January 5, 2007
    Publication date: October 25, 2007
    Applicant: N.V. Nutricia
    Inventors: Gunther Sawatzki, Bernd Stahl
  • Publication number: 20070098762
    Abstract: The present invention relates to a method for enhancing the immune system and the treatment and/or prevention of immune system related disorders in a mammal, particularly newborns, said method comprising the administration of acid oligosaccharide and neutral oligosaccharide. Food compositions suitable for use in the above method are also provided.
    Type: Application
    Filed: October 25, 2004
    Publication date: May 3, 2007
    Applicant: N.V. NUTRICIA
    Inventors: Bernd Stahl, Laura M'Rabet, Arjan Vos, Johan Garssen, Gunther Boehm
  • Publication number: 20070054877
    Abstract: Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells. Said preparation contains at least one carbohydrate having an uronic acid unit on one of the ends thereof. 10 to 100% of the present, terminal uronic acid units pertaining to the carbohydrates are provided with a double bond that is especially situated between the C4 and C5 atom.
    Type: Application
    Filed: August 29, 2006
    Publication date: March 8, 2007
    Applicant: N.V. NUTRICIA
    Inventors: Bernd Stahl, Gunther Boehm
  • Publication number: 20070004656
    Abstract: The invention relates to novel enzymes, which transfer sialic acid from a donor molecule onto an acceptor molecule (trans-sialidases). The enzymes are isolated from the protozoan Trypanosoma congolense.
    Type: Application
    Filed: December 11, 2003
    Publication date: January 4, 2007
    Applicant: RENISHAW PLC
    Inventors: Joachim Schmitt, Gunter Boehm, Bernd Stahl, Roland Schauer, Evelin Tiralongo, Silke Schrader
  • Publication number: 20060105990
    Abstract: Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells. Said preparation contains at least one carbohydrate having an uronic acid unit on one of the ends thereof. 10 to 100% of the present, terminal uronic acid units pertaining to the carbohydrates are provided with a double bond that is especially situated between the C4 and C5 atom.
    Type: Application
    Filed: December 22, 2005
    Publication date: May 18, 2006
    Applicant: N.V. NUTRICIA
    Inventors: Bernd Stahl, Gunther Boehm
  • Patent number: 7010114
    Abstract: The inventive SS7 signaling server for routing SS7 links, includes a signaling transfer point (STP) and a signaling application server (SAS). STP and SAS have different functionalities. The STP has at least one external interface to connect the STP via at least one SS7 link to at least one telecommunications unit, and an internal interface to connect the STP to the SAS. The STP processes incoming SS7 messages, e.g. in the SCCP layer. The SAS is capable to process at least one, advantageously at least two different application service requests. The STP identifies a single application service request in one incoming SS7 message and provides the identified single application service request to the SAS for further processing. The SAS has e.g. two TCAP processes to identify two different application services, e.g. INAP and MAP. STP and SAS are interconnected via an internal interworking protocol, e.g. using TCP/IP.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: March 7, 2006
    Assignee: Alcatel
    Inventors: Bernd Stahl, Uwe Spitzer, Rudolf Salomon, Albert Henger, Andreas Breiholz
  • Publication number: 20050222080
    Abstract: Described is the use of in particular homopolymer cycloglycans having a ring-shaped base structure of 2 to 40 monosaccharides in the ring, for preventing the invasion and infection of mammal cells by pathogens, and for combating diseases caused by such pathogens, and food compositions, dietetic compositions and pharmaceutical compositions containing these cycloglycans.
    Type: Application
    Filed: January 20, 2003
    Publication date: October 6, 2005
    Applicant: N.V. Nutricia
    Inventors: Bernd Stahl, Berndt Finke, Joachim Schmitt, Werner Goebel, Jorg Slaghuis, Gunther Boehm