Patents by Inventor Bernhard Günther

Bernhard Günther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200206241
    Abstract: The invention provides novel pharmaceutical compositions for the treatment of increased intraocular pressure based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The compositions can be administered topically into the eye. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: December 31, 2019
    Publication date: July 2, 2020
    Applicant: NOVALIQ GMBH
    Inventors: Bastian THEISINGER, Sonja THEISINGER, Bernhard GÜNTHER
  • Publication number: 20200188318
    Abstract: The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: September 20, 2019
    Publication date: June 18, 2020
    Inventors: Bernhard Günther, Bastian Theisinger, Sonja Theisinger, Dieter Scherer
  • Patent number: 10576154
    Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: March 3, 2020
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Dieter Scherer, Anthony Pettigrew, Bastian Theisinger, Sonja Theisinger
  • Publication number: 20200060987
    Abstract: A pharmaceutical composition comprising a semifluorinated alkane of formula (I): F(CF2)n(CH2)mH, wherein n is an integer from 4 to 6, and m is an integer from 5 to 8, for use in the treatment or prevention of a disease or condition relating to an ocular surface of an eye of an individual, wherein the individual is a contact lens wearer, and wherein the contact lens is a hydro gel contact lens and the composition is administered topically to a surface of the eye of the individual before the contact lens is inserted to the eye of the individual and/or during contact lens wear and/or after the contact lens has been removed from the eye of the individual, or wherein the contact lens is a silicone hydrogel contact lens and the composition is administered topically to a surface of the eye of the individual after the contact lens has been removed from the eye of the individual.
    Type: Application
    Filed: May 9, 2018
    Publication date: February 27, 2020
    Inventors: Bernhard GÜNTHER, Markus BEIER, Oliver SCHLÜTER
  • Patent number: 10555953
    Abstract: The invention provides novel pharmaceutical compositions based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: February 11, 2020
    Assignee: NOVALIQ GMBH
    Inventors: Bastian Theisinger, Sonja Theisinger, Bernhard Günther
  • Patent number: 10525062
    Abstract: The invention provides novel pharmaceutical compositions for the treatment of increased intraocular pressure based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The compositions can be administered topically into the eye. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: January 7, 2020
    Assignee: NOVALIQ GMBH
    Inventors: Bastian Theisinger, Sonja Theisinger, Bernhard Günther
  • Publication number: 20190343793
    Abstract: The present invention provides a pharmaceutical composition comprising: a) a therapeutically effective amount of at least one cannabinoid receptor binding ligand, and b) a liquid vehicle comprising at least one semifluorinated alkane; as well as the use of such pharmaceutical compositions as a medicament.
    Type: Application
    Filed: September 27, 2017
    Publication date: November 14, 2019
    Inventors: Bernhard GÜNTHER, Frank LÖSCHER, Sonja KRÖSSER, Philipp STEVEN
  • Publication number: 20190328717
    Abstract: The present invention relates to a pharmaceutical composition comprising a therapeutically effective amount of tacrolimus and a liquid vehicle comprising at least one semifluorinated alkane for use in a method of treating an intraocular inflammatory eye disease.
    Type: Application
    Filed: December 14, 2017
    Publication date: October 31, 2019
    Inventors: Bernhard GÜNTHER, Dieter SCHERER, Heping XU
  • Patent number: 10449164
    Abstract: The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: October 22, 2019
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Bastian Theisinger, Sonja Theisinger, Dieter Scherer
  • Publication number: 20190274970
    Abstract: The present invention provides a pharmaceutical composition comprising 1-perfluorohexyl-octane (F6H8) for use in the therapy, treatment, prevention or amelioration of anterior or posterior blepharitis, preferably posterior blepharitis or symptoms associated therewith. Furthermore, the present invention provides a pharmaceutical kit for the therapy of anterior or posterior blepharitis or symptoms associated therewith.
    Type: Application
    Filed: September 20, 2017
    Publication date: September 12, 2019
    Inventors: Bernhard GÜNTHER, Frank LÖSCHER, Sonja KRÖSSER
  • Publication number: 20190256591
    Abstract: The invention provides novel compositions of antibodies based on liquid vehicles selected from semifluorinated alkanes. The use of these vehicles provides for improved stability and shelf-life of antibodies and their derivatives. The compositions are useful for topical administration or for parenteral injection.
    Type: Application
    Filed: March 6, 2019
    Publication date: August 22, 2019
    Applicant: NOVALIQ GMBH
    Inventors: Bernhard Günther, Dieter Scherer, Anthony Pettigrew, Gesche Graf
  • Publication number: 20190240234
    Abstract: The invention provides novel pharmaceutical compositions based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: April 17, 2019
    Publication date: August 8, 2019
    Applicant: NOVALIQ GMBH
    Inventors: Bastian THEISINGER, Sonja THEISINGER, Bernhard GÜNTHER
  • Patent number: 10369117
    Abstract: The invention provides novel compositions comprising at least two or more semifluorinated alkanes. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue, such as for use in the treatment of keratoconjunctivitis sicca (dry eye) and/or meibomian gland dysfunction and symptoms associated therewith. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: August 6, 2019
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Bastian Theisinger, Sonja Theisinger, Dieter Scherer
  • Publication number: 20190224123
    Abstract: The invention provides liquid compositions in the form of physically stable emulsions comprising a semifluorinated alkane. The semifluorinated alkane is comprised in the dispersed phase, which may also include an active pharmaceutical ingredient. One of the preferred active ingredients is propofol. The compositions are optionally heat sterilisable and can be used for pharmaceutical or cosmetic product applications, and administered topically, intravenously, or via other routes.
    Type: Application
    Filed: January 28, 2019
    Publication date: July 25, 2019
    Applicant: NOVALIQ GMBH
    Inventors: Bastian THEISINGER, Sonja THEISINGER, Bernhard GÜNTHER
  • Patent number: 10273298
    Abstract: The invention provides novel compositions of antibodies based on liquid vehicles selected from semifluorinated alkanes. The use of these vehicles provides for improved stability and shelf-life of antibodies and their derivatives. The compositions are useful for topical administration or for parenteral injection.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: April 30, 2019
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Dieter Scherer, Anthony Pettigrew, Gesche Graf
  • Publication number: 20180360908
    Abstract: The invention provides pharmaceutical compositions comprising about 0.05 to 0.1% (w/v) cyclosporine dissolved in 1-perfluorobutyl-pentane for use in the topical treatment of dry eye disease and provides for dosing and treatment methods thereof. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 20, 2018
    Inventors: Markus BEIER, Jörg HAISSER, Alice MEIDES, Sonja KRÖSSER, Hartmut VOSS, Frank LÖSCHER, Bernhard GÜNTHER
  • Publication number: 20180326066
    Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: July 20, 2018
    Publication date: November 15, 2018
    Inventors: Bernhard GÜNTHER, Dieter SCHERER, Anthony PETTIGREW, Bastian THEISINGER, Sonja THEISINGER
  • Publication number: 20180303849
    Abstract: The invention provides novel pharmaceutical compositions for the treatment of increased intraocular pressure based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The compositions can be administered topically into the eye. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: June 25, 2018
    Publication date: October 25, 2018
    Applicant: NOVALIQ GMBH
    Inventors: Bastian THEISINGER, Sonja THEISINGER, Bernhard GÜNTHER
  • Patent number: 10058615
    Abstract: The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be used as medicines that are topically administered to an eye or ophthalmic tissue. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: August 28, 2018
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Dieter Scherer, Anthony Pettigrew, Bastian Theisinger, Sonja Theisinger
  • Patent number: 10045996
    Abstract: The invention provides novel pharmaceutical compositions for the treatment of increased intraocular pressure based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The compositions can be administered topically into the eye. The invention further provides kits comprising such compositions.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: August 14, 2018
    Assignee: NOVALIQ GMBH
    Inventors: Bastian Theisinger, Sonja Theisinger, Bernhard Günther