Patents by Inventor Bettina Möckel

Bettina Möckel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide sequences which code for the lysR3 gene
    Patent number: 6812006
    Abstract: The present invention relates to polynucleotides corresponding to the lysR3 gene and which encode a LysR3 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR3 transcriptional regulator activity.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: November 2, 2004
    Assignee: Degussa AG
    Inventors: Bettina Moeckel, Caroline Kreutzer
  • Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
    Patent number: 6808914
    Abstract: The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: October 26, 2004
    Assignee: Degussa AG
    Inventors: Yvonne Tilg, Bernhard Eikmanns, Lothar Eggeling, Hermann Sahm, Bettina Möckel
  • Nucleotide sequences which code for the ccpa2 gene
    Publication number: 20040209285
    Abstract: The invention relates to polynucleotides corresponding to the ccpA2 gene and which encode a CcpA2 catabolite control protein, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having CcpA2 catabolite control activity.
    Type: Application
    Filed: December 2, 2003
    Publication date: October 21, 2004
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Caroline Kreutzer, Thomas Hermann, Mike Farwick, Achim Marx, Walter Pfefferle
  • Nucleotide sequences which encode the pfk gene
    Patent number: 6806068
    Abstract: The present invention is directed to nucleotide sequences coding for phosphofructokinase which have been derived from Corynebacterium glutamicum.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: October 19, 2004
    Assignee: Degussa AG Dusseldorf
    Inventors: Bettina Möckel, Walter Pfefferle
  • Nucleotide sequences which code for the rpoB gene
    Publication number: 20040180359
    Abstract: The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the &bgr;-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the &bgr;-subunit of RNA polymerase B.
    Type: Application
    Filed: November 13, 2003
    Publication date: September 16, 2004
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the rpoB gene
    Patent number: 6783967
    Abstract: The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the &bgr;-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the &bgr;-subunit of RNA polymerase B.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: August 31, 2004
    Assignee: Degussa AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the eno gene
    Patent number: 6713289
    Abstract: The present invention is directed to nucleotide sequences coding for a bacterial enolase enzyme. These sequences may be used in improved methods for the fermentative preparation of amino acids using coryneform bacteria.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: March 30, 2004
    Assignee: Degussa AG
    Inventors: Bettina Möckel, Walter Pfefferle, Thomas Hermann, Alfred Pühler, Jörn Kalinowski, Brigitte Bathe
  • Polynucleotides encoding the nadA gene and methods of producing nicotinic acid or nicotinic acid derivatives
    Patent number: 6692946
    Abstract: The present invention relates to polynucleotides corresponding to the nadA gene and which encode the quinolinate synthetase A protein, methods of producing nicotinic acid or nicotinic acid derivatives, and methods of screening for polynucleotides which encode proteins having quinolinate synthetase A activity.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: February 17, 2004
    Assignee: Degussa AG
    Inventors: Christine Bastuck, Brigitte Bathe, Nicole Dusch, Bettina Moeckel, Georg Thierbach
  • Polynucleotides encoding the nadC gene and methods of producing nicotinic acid or nicotinic acid derivatives
    Patent number: 6689587
    Abstract: The present invention relates to polynucleotides corresponding to the nadC gene and which encode the nicotinate nucleotide pyrophosphorylase protein, methods of producing nicotinic acid or nicotinic acid derivatives, and methods of screening for polynucleotides which encode proteins having nicotinate nucleotide pyrophosphorylase activity.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: February 10, 2004
    Assignee: Degussa AG
    Inventors: Christine Bastuck, Brigitte Bathe, Nicole Dusch, Bettina Moeckel, Georg Thierbach
  • Nucleotide sequences which code for the CcpA2 gene
    Patent number: 6689586
    Abstract: The invention relates to polynucleotides corresponding to the ccpA2 gene and which encode a CcpA2 catabolite control protein, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having CcpA2 catabolite control activity.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: February 10, 2004
    Assignee: Degussa AG
    Inventors: Bettina Moeckel, Caroline Kreutzer, Thomas Hermann, Mike Garwick, Achim Marx, Walter Pfefferle
  • Nucleotide sequences coding for the PTSI protein
    Patent number: 6680187
    Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which the ptsI gene is enhanced.
    Type: Grant
    Filed: September 13, 2001
    Date of Patent: January 20, 2004
    Assignee: Degussa AG
    Inventors: Bettina Moeckel, Stephan Hans, Natalie Schischka, Walter Pfefferle
  • Polynucleotide encoding a diaminopimelate epimerase from Corynebacterium glutamicum
    Patent number: 6670156
    Abstract: The present application is directed to a diaminopimelate epimerase from Corynebacterium glutamicum and to polynucleotides encoding this enzyme. The gene has been given the designation “dapF.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: December 30, 2003
    Assignee: Degussa AG
    Inventors: Bettina Möckel, Walter Pfefferle, Brigitte Bathe, Jorn Kalinowski, Oliver Kirchner, Michael Hartmann, Alfred Pühler
  • Nucleotide sequences which code for the cma gene
    Patent number: 6638753
    Abstract: The invention relates to a genetically modified coryneform bacterium, the cma gene of which is amplified, and an isolated polynucleotide which codes for cyclopropane-mycolic acid synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the cma gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: October 28, 2003
    Assignees: Degussa AG, Forschungszentrum Julich GmbH
    Inventors: Madhavan Nampoothiri K., Bettina Möckel, Lothar Eggeling, Hermann Sahm
  • Nucleotide sequences coding for the ptsI protein
    Publication number: 20030198991
    Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which the ptsI gene is enhanced.
    Type: Application
    Filed: June 13, 2003
    Publication date: October 23, 2003
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Stephan Hans, Natalie Schischka, Walter Pfefferle
  • Nucleotide sequences which code for the zwa1 gene
    Patent number: 6632644
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID NO 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID NO 2 c) polynucleotide which is complementary to the polynucleotides of a) and b) and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and processes for the fermentative preparation of L-amino acid with amplification of the zwa1 gene in the coryneform bacteria employed.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: October 14, 2003
    Assignee: DeGussa AG
    Inventors: Bettina Möckel, Walter Pfefferle, Achim Marx, Jörn Kalinowski, Brigitte Bathe, Alfred Pühler
  • Nucleotide sequences encoding the sucC and sucD genes
    Patent number: 6623946
    Abstract: Polynucleotides that contain polynucleotide sequences encoding the sucC and sucD genes, selected from the group a) a polynucleotide that is at least 70% identical to a polynucleotide encoding a polypeptide that contains the amino acid sequence of SEQ ID NO:2, b) a polynucleotide that is at least 70% identical to a polynucleotide encoding a polypeptide that contains the amino acid sequence of SEQ ID NO:3, c) a polynucleotide encoding a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID NO:2, d) a polynucleotide encoding a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID NO:3, e) a polynucleotide that is complementary to one of the polynucleotides of a), b), c) or d), and f) a polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b), c), d) or e), a process for the fermentative production of L-amino acids using coryneform bacter
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: September 23, 2003
    Assignee: Degussa AG
    Inventors: Bettina Möckel, Walter Pfefferle, Achim Marx
  • Nucleotide sequences coding for the 1ysR1 gene
    Publication number: 20030170780
    Abstract: The present invention relates to polynucleotides corresponding to the lysR1 gene and which encode a LysR1 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR3 transcriptional regulator activity.
    Type: Application
    Filed: July 13, 2001
    Publication date: September 11, 2003
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Mike Farwick, Thomas Hermann, Caroline Kreutzer, Walter Pfefferle
  • Nucleotide sequences which code for the rpoB gene
    Publication number: 20030166884
    Abstract: The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the &bgr;-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the &bgr;-subunit of RNA polymerase B.
    Type: Application
    Filed: February 19, 2002
    Publication date: September 4, 2003
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the lysR3 gene
    Publication number: 20030100099
    Abstract: The present invention relates to polynucleotides corresponding to the lysR3 gene and which encode a LysR3 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR3 transcriptional regulator activity.
    Type: Application
    Filed: December 11, 2001
    Publication date: May 29, 2003
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Caroline Kreutzer
  • Nucleotide sequences coding for the cls gene
    Patent number: 6562607
    Abstract: This invention relates to a genetically modified coryneform bacterium, the cls gene of which is amplified, and to an isolated polynucleotide, which codes for cardiolipin synthase from coryneform bacteria and to a process for the fermentative production of L-amino acids with amplification of the cls gene in the bacteria and to the use of the polynucleotide as a primer or hybridization probe.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: May 13, 2003
    Assignees: Degussa-Huls Aktiengesellschaft, Forschungszentrum Julich GmbH
    Inventors: Madhavan Nampoothiri K., Bettina Möckel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm