Patents by Inventor Bettina Möckel

Bettina Möckel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the fermentative preparation of L-amino acids using coryneform bacteria
    Publication number: 20020168732
    Abstract: The invention relates to a process for the preparation of L-amino acids in which the following steps are carried out,
    Type: Application
    Filed: March 26, 2001
    Publication date: November 14, 2002
    Inventors: Bettina Moeckel, Thomas Hermann, Walter Pfefferle
  • Nucleotide sequences which code for the rpsL gene
    Publication number: 20020155557
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: February 15, 2002
    Publication date: October 24, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Stefan Hans, Caroline Kreutzer, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences coding for the ccpA1 gene
    Publication number: 20020151001
    Abstract: The present invention provides isolated polynucleotides containing a polynucleotide sequence which is:
    Type: Application
    Filed: August 27, 2001
    Publication date: October 17, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Caroline Kreutzer
  • Polynucleotides encoding the nadA gene and methods of producing nicotinic acid or nicotinic acid derivatives
    Publication number: 20020137163
    Abstract: The present invention relates to polynucleotides corresponding to the nadA gene and which encode the quinolinate synthetase A protein, methods of producing nicotinic acid or nicotinic acid derivatives, and methods of screening for polynucleotides which encode proteins having quinolinate synthetase A activity.
    Type: Application
    Filed: February 22, 2001
    Publication date: September 26, 2002
    Applicant: Degussa-Huels Aktiengesellschaft
    Inventors: Christine Bastuck, Brigitte Bathe, Nicole Dusch, Bettina Moeckel, Georg Thierbach
  • Polynucleotides encoding the nadC gene and methods of producing nicotinic acid or nicotinic acid derivatives
    Publication number: 20020137169
    Abstract: The present invention relates to polynucleotides corresponding to the nadC gene and which encode the nicotinate nucleotide pyrophosphorylase protein, methods of producing nicotinic acid or nicotinic acid derivatives, and methods of screening for polynucleotides which encode proteins having nicotinate nucleotide pyrophosphorylase activity.
    Type: Application
    Filed: February 22, 2001
    Publication date: September 26, 2002
    Applicant: Degussa-Huels Aktiengesellschaft
    Inventors: Christine Bastuck, Brigitte Bathe, Nicole Dusch, Bettina Moeckel, Georg Thierbach
  • Nucleotide sequences coding for the PTSI protein
    Publication number: 20020132323
    Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which the ptsI gene is enhanced.
    Type: Application
    Filed: September 13, 2001
    Publication date: September 19, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Stephan Hans, Natalie Schischka, Walter Pfefferle
  • Nucleotide sequences which code for the rpoB gene
    Publication number: 20020119537
    Abstract: The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the &bgr;-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the &bgr;-subunit of RNA polymerase B.
    Type: Application
    Filed: June 25, 2001
    Publication date: August 29, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the RPSL gene
    Publication number: 20020119549
    Abstract: The present invention relates to polynucleotides corresponding to the rpsL gene and which encode ribosomal protein S12, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having ribosomal protein S12 activity.
    Type: Application
    Filed: October 31, 2001
    Publication date: August 29, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Hans Stephan, Caroline Kreutzer, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the metE gene
    Publication number: 20020110877
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: August 2, 2001
    Publication date: August 15, 2002
    Applicant: DEGUSSA AG
    Inventors: Brigitte Bathe, Bettina Moeckel, Walter Pfefferle, Klaus Huthmacher, Christian Rueckert, Joern Kalinowski, Alfred Puehler, Michael Binder, Dieter Greissinger, Georg Thierbach
  • Nucleotide sequences which code for the metY gene
    Publication number: 20020110878
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: August 2, 2001
    Publication date: August 15, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Walter Pfefferle, Klaus Huthmacher, Christian Rueckert, Joern Kalinowski, Alfred Puehler, Michael Binder, Dieter Greissinger, Georg Thierbach
  • Nucleotide sequences coding for the luxR gene
    Publication number: 20020086404
    Abstract: The present invention relates to polynucleotides corresponding to the luxR gene and which encode a LuxR transcriptional activator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LuxR transcriptional activation activity.
    Type: Application
    Filed: July 13, 2001
    Publication date: July 4, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Caroline Kreutzer, Brigitte Bathe
  • Nucleotide sequences for encoding of the lysR2-Gene
    Publication number: 20020081674
    Abstract: Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: July 24, 2001
    Publication date: June 27, 2002
    Applicant: Degussa AG
    Inventors: Bettina Moeckel, Mike Farwick, Thomas Hermann, Caroline Kreutzer, Walter Pfefferle
  • Nucleotide sequences which code for the CcpA2 gene
    Publication number: 20020068336
    Abstract: The invention relates to polynucleotides corresponding to the ccpA2 gene and which encode a CcpA2 catabolite control protein, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having CcpA2 catabolite control activity.
    Type: Application
    Filed: August 27, 2001
    Publication date: June 6, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Caroline Kreutzer, Thomas Hermann, Mike Garwick, Achim Marx, Walter Pfefferle
  • Nucleotide sequence which code for the metH gene
    Publication number: 20020048793
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: August 2, 2001
    Publication date: April 25, 2002
    Applicant: DEGUSSA AG
    Inventors: Brigitte Bathe, Bettina Moeckel, Walter Pfefferle, Klaus Huthmacher, Christian Rueckert, Joern Kalinowski, Alfred Puehler, Michael Binder, Dieter Greissinger, Georg Thierbach
  • Nucleotide sequences which code for the metF gene
    Publication number: 20020049305
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: August 2, 2001
    Publication date: April 25, 2002
    Applicant: DEGUSSA AG
    Inventors: Brigitte Bathe, Bettina Moeckel, Walter Pfefferle, Klaus Huthmacher, Michael Binder, Dieter Greissinger, Georg Thierbach
  • Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
    Patent number: 6361986
    Abstract: The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: March 26, 2002
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Yvonne Tilg, Bernd Eikmanns, Lothar Eggeling, Hermann Sahm, Bettina Möckel
  • Nucleotide sequences coding for the lipA gene
    Publication number: 20020031810
    Abstract: Nucleotide sequences from coryneform bacteria coding for the lipA gene and a process for fermentative preparation of amino acids by attenuation of the lipA gene.
    Type: Application
    Filed: August 29, 2001
    Publication date: March 14, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Walter Pfefferle, Michael Buchholz
  • Nucleotide sequences coding for the lipB gene
    Publication number: 20020031809
    Abstract: The invention relates to polynucleotides corresponding to the lipB gene and which encode a lipoprotein ligase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having lipoprotein ligase B activity.
    Type: Application
    Filed: August 31, 2001
    Publication date: March 14, 2002
    Applicant: Degussa AG
    Inventors: Bettina Moeckel, Walter Pfefferle, Michael Buchholz
  • Production of L-isoleucine by means of recombinant microorganisms with deregulated threonine dehydratase
    Patent number: 6107063
    Abstract: The invention relates to processes for the microbial production of L-isoleucine. To this end, in a gene in vitro of a threonine dehydratse, one or more bases in the gene region coding the enzyme's allosteric domains are exchanged in such a way that at least one amino acid in the amino acid sequence of the allosteric domains of the enzyme is replaced by another so that the enzyme is no longer inhibited by L-isoleucine feedback. Furthermore, concrete amino acid exchanges in the amino acid sequence of the enzyme are effected in a gene in vitro of a threonin dehydratase of Corynebacterium glutamicum by base exchange both outside and inside and outside the gene region coding the allosteric domains of the enzyme si that, after the transformation of such mutated threonine dehydratase genes into a threonine or L-isoleucine-producing host cell, the latter repeatedly forms L-isoleucine.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: August 22, 2000
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Bettina Moeckel, Lothar Eggeling, Hermann Sahm