Patents by Inventor Bettina Mockel

Bettina Mockel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide sequences which code for the pgsA2 gene
    Publication number: 20020155555
    Abstract: The invention relates to a genetically modified coryneform bacterium, the pgsA2 gene of which is amplified, and an isolated polynucleotide which codes for CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the pgsA2 gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Application
    Filed: May 16, 2001
    Publication date: October 24, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Method to monitor a fermentation process
    Publication number: 20020151700
    Abstract: The present invention provides arrays of single- or doublestranded desoxyribonucleic acid (DNA) probes immobilized on solid supports and for using those probe arrays to detect specific nucleic acid sequences contained in a target nucleic acid in a sample, especially a method to monitore a fermentation process.
    Type: Application
    Filed: July 17, 2001
    Publication date: October 17, 2002
    Inventors: Mike Farwick, Jennifer Brehme, Thomas Hermann, Brigitte Bathe, Achim Marx, Bettina Mockel, Mechthild Rieping, Eugen Ermantraut, Thomas Ellinger, Klaus Huthmacher, Walter Pfefferle
  • Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
    Publication number: 20020142405
    Abstract: The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.
    Type: Application
    Filed: December 21, 2001
    Publication date: October 3, 2002
    Inventors: Yvonne Tilg, Bernd Eikmanns, Lothar Eggeling, Hermann Sahm, Bettina Mockel
  • Nucleotide sequences which code for the cstA gene
    Publication number: 20020137912
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the cstA gene, and a host-vector system having a coryneform host bacterium in which the cstA gene is present in attenuated form and a vector which carries at least the cstA gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: August 24, 2001
    Publication date: September 26, 2002
    Inventors: Bettina Mockel, Achim Marx, Walter Pfefferle, Mike Farwick, Thomas Hermann
  • Nucleotide sequences which code for the zwa1 gene
    Publication number: 20020127663
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: December 8, 2000
    Publication date: September 12, 2002
    Inventors: Bettina Mockel, Walter Pfefferle, Achim Marx, Jorn Kalinowski, Brigitte Bathe, Alfred Puhler
  • Novel nucleotide sequences encoding the zwa2 gene
    Publication number: 20020106748
    Abstract: The invention provides novel isolated polynucleotides containing a polynucleotide sequence chosen from the group
    Type: Application
    Filed: December 4, 2000
    Publication date: August 8, 2002
    Inventors: Bettina Mockel, Anke Weissenborn, Walter Pfefferle, Achim Marx, Alfred Puhler, Jorn Kalinowski, Brigitte Bathe, Nicole Dusch
  • Novel nucleotide sequences coding for the cls gene
    Publication number: 20020102667
    Abstract: This invention relates to a genetically modified coryneform bacterium, the cls gene of which is amplified, and to an isolated polynucleotide, which codes for cardiolipin synthase from coryneform bacteria and to a process for the fermentative production of L-amino acids with amplification of the cls gene in the bacteria and to the use of the polynucleotide as a primer or hybridization probe.
    Type: Application
    Filed: May 4, 2001
    Publication date: August 1, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Sequences which code for the sigE gene
    Publication number: 20020103356
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: August 24, 2001
    Publication date: August 1, 2002
    Inventors: Bettina Mockel, Thomas Hermann, Mike Farwick, Michael Binder, Walter Pfefferle
  • Nucleotide sequences encoding the ptsH gene
    Publication number: 20020094554
    Abstract: The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising
    Type: Application
    Filed: January 8, 2001
    Publication date: July 18, 2002
    Inventors: Mike Farwick, Bettina Mockel, Walter Pfefferle
  • Nucleotide sequences which code for the pck gene
    Patent number: 6420151
    Abstract: Isolated polynucleotide from coryneform bacteria, comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for the polypeptide which is expressed by the pck gene contained on vector pK19mobsacB&Dgr;pck in the deposited E.coli strain DSM 13047, c) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, d) polynucleotide which is complementary to the polynucleotides of a), b) or c) and e) polynucleotide comprising at least 15 successive bases of the polynucleotide sequence of a), b), c) or d).
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: July 16, 2002
    Assignee: Degussa-Huls AG
    Inventors: Bernard Eikmanns, Christian Riedel, Hermann Sahm, Bettina Mockel
  • Nucleotide sequences encoding the ptsH gene
    Publication number: 20020090700
    Abstract: The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising
    Type: Application
    Filed: March 29, 2001
    Publication date: July 11, 2002
    Inventors: Mike Farwick, Bettina Mockel, Walter Pfefferle
  • L-lysine-producing corynebacteria and process for the preparation of L-lysine
    Publication number: 20020086371
    Abstract: The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
    Type: Application
    Filed: March 8, 2001
    Publication date: July 4, 2002
    Applicant: Degussa-Huls Aktiengesellschaft
    Inventors: Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek
  • Nucleotide sequences which code for the citB gene
    Publication number: 20020086372
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the citB gene, and a host-vector system having a coryneform host bacterium in which the citB gene is present in attenuated form and a vector which carries at least the citB gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: August 31, 2001
    Publication date: July 4, 2002
    Inventors: Bettina Mockel, Thomas Hermann, Mike Farwick, Walter Pfefferle, Achim Marx
  • Nucleotide sequences which code for the citA gene
    Publication number: 20020081672
    Abstract: The invention relates to isolated polynucleotides comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: March 13, 2001
    Publication date: June 27, 2002
    Inventors: Bettina Mockel, Mike Farwick, Thomas Hermann, Achim Marx, Walter Pfefferle
  • Nucleotide sequences which code for the eno gene
    Publication number: 20020082403
    Abstract: The present invention is directed to nucleotide sequences coding for a bacterial enolase enzyme. These sequences may be used in improved methods for the fermentative preparation of amino acids using coryneform bacteria.
    Type: Application
    Filed: May 21, 2001
    Publication date: June 27, 2002
    Inventors: Bettina Mockel, Walter Pfefferle, Thomas Hermann, Alfred Puhler, Jorn Kalinowski, Brigitte Bathe
  • Novel nucleotide sequences coding for the glbO gene
    Publication number: 20020081673
    Abstract: Isolated polynucleotides containing at least one nucleic acid sequence selected from the group
    Type: Application
    Filed: March 22, 2001
    Publication date: June 27, 2002
    Inventors: Bettina Mockel, Achim Marx, Walter Pfefferle
  • Nucleotide sequences coding for the genes sucC and sucD
    Publication number: 20020072099
    Abstract: The invention relates to polynucleotides that contain poLynucleotide sequences coding for the genes sucC and sucD, selected from the group
    Type: Application
    Filed: April 20, 2001
    Publication date: June 13, 2002
    Inventors: Bettina Mockel, Walter Pfefferle, Achim Marx
  • NEW NUCLEOTIDE SEQUENCES WHICH CODE FOR PCK GENE
    Publication number: 20020065403
    Abstract: Isolated polynucleotide from coryneform bacteria, comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: December 7, 1999
    Publication date: May 30, 2002
    Inventors: BERNHARD EIKMANNS, CHRISTIAN RIEDEL, HERMANN SAHM, BETTINA MOCKEL
  • Nucleotide sequences which code for the acp gene
    Publication number: 20020055154
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: May 10, 2001
    Publication date: May 9, 2002
    Inventors: Bettina Mockel, Anke Weissenborn, Walter Pfefferle, Hermann Sahm, Lothar Eggeling, Madhavan Nampoothiri
  • L-lysine-producing corynebacteria and process for the preparation of lysine
    Publication number: 20020055153
    Abstract: The invention relates to L-lysine-producing strains of corynebacteria with enhanced pyc gene (pyruvate carboxylase gene), in which strains additional genes, chosen from the group consisting of the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the lysE gene (lysine export carrier gene) and the dapB gene (dihydrodipicolinate reductase gene), but especially the dapA gene, are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
    Type: Application
    Filed: March 19, 2001
    Publication date: May 9, 2002
    Applicant: Degussa-Huls Aktiengesellschaft
    Inventors: Caroline Kreutzer, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek