Patents by Inventor Bettina Mockel

Bettina Mockel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the fermentative preparation of L-amino acids using coryneform bacteria
    Patent number: 6379934
    Abstract: The invention provides a process for the fermentative preparation of L-amino acids using coryneform bacteria, in which the subunit carrying the biotin-carboxyl carrier protein domain and the biotin-carboxylase domain of the nucleotide sequence encoding the enzyme acetyl-CoA carboxylase (accBC gene) is amplified, in particular is overexpressed.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: April 30, 2002
    Assignee: Degussa AG
    Inventors: Yvonne Tilg, Bernd Eikmanns, Lothar Eggeling, Hermann Sahm, Bettina Mockel, Walter Pfefferle
  • Nucleotide sequences which code for the ppsA gene
    Publication number: 20020045224
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the ppsA gene, and a host-vector system having a coryneform host bacterium in which the ppsA gene is present in attenuated form and a vector which carries at least the ppsA gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 5, 2001
    Publication date: April 18, 2002
    Inventors: Bettina Mockel, Achim Marx, Christine Bastuck, Michael Buchholz, Walter Pfefferle
  • Nucleotide sequences which code for the cma gene
    Publication number: 20020042106
    Abstract: The invention relates to a genetically modified coryneform bacterium, the cma gene of which is amplified, and an isolated polynucleotide which codes for cyclopropane-mycolic acid synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the cma gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Application
    Filed: May 1, 2001
    Publication date: April 11, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Lothar Eggeling, Hermann Sahm
  • Nucleotide sequences which code for the fadD15 gene
    Publication number: 20020042107
    Abstract: The invention relates to a genetically modified coryneform bacterium, the fadD15 gene of which is amplified, and an isolated polynucleotide which codes for acyl-CoA synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the fadD15 gene in the bacteria and the use of the polynucleotide as a primer or hybridization probe.
    Type: Application
    Filed: May 16, 2001
    Publication date: April 11, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Nucleotide sequences encoding the glk-gene
    Publication number: 20020040129
    Abstract: The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising:
    Type: Application
    Filed: November 30, 2000
    Publication date: April 4, 2002
    Inventors: Bettina Mockel, Walter Pfefferle
  • Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
    Patent number: 6361986
    Abstract: The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: March 26, 2002
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Yvonne Tilg, Bernd Eikmanns, Lothar Eggeling, Hermann Sahm, Bettina Möckel
  • Process for the fermentative production of L-amino acids using coryneform bacteria
    Patent number: 6355454
    Abstract: This invention relates to a process for the production of L-amino acids using coryneform bacteria, in which the glutamate dehydrogenase gene is amplified.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: March 12, 2002
    Assignee: Degussa Huls AG
    Inventors: Achim Marx, Bettina Mockel, Walter Pfefferle, Hermann Sahm, Albert De Graaf, Lothar Eggeling
  • Process for the production of L-amino acids by fermentation using coryneform bacteria
    Publication number: 20020028490
    Abstract: The invention relates to a process for the production of L-amino acids by fermentation using coryneform bacteria in which the mqo gene is enhanced.
    Type: Application
    Filed: May 10, 2001
    Publication date: March 7, 2002
    Inventors: Douwe Molenaar, Michel Eduard Van Der Rest, Bettina Mockel
  • Novel nucleotide sequences encoding the gpm gene
    Publication number: 20020002275
    Abstract: The invention relates to an isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising:
    Type: Application
    Filed: November 29, 2000
    Publication date: January 3, 2002
    Inventors: Bettina Mockel, Walter Pfefferle
  • Nucleotide sequences encoding the dapC gene and process for the production of L-lysine
    Publication number: 20010049123
    Abstract: The invention relates to an isolated polynucleotide from coryneform bacteria containing at least one polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: March 22, 2001
    Publication date: December 6, 2001
    Inventors: Bettina Mockel, Anke Weissenborn, Walter Pfefferle, Michael Hartmann, Jorn Kalinowski, Alfred Puhler
  • L-lysine-producing corynebacteria and process for the preparation of l-lysine
    Patent number: 6200785
    Abstract: The invention relates to L-lysine-producing strains of corynebacteria with amplified lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are amplified and, in particular, overexpressed, and to a process for the preparation of L-lysine.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: March 13, 2001
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfeffere, Lothar Eggeling, Hermann Sahm, Miroslav Patek