Patents by Inventor Betty A. Diamond

Betty A. Diamond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF AUTISM SPECTRUM DISORDER USING DECOY ANTIGENS TO MATERNAL BRAIN-REACTIVE ANTIBODIES
    Publication number: 20230067234
    Abstract: Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies.
    Type: Application
    Filed: June 21, 2022
    Publication date: March 2, 2023
    Inventors: Betty A. Diamond, Simone Mader, Lior Brimberg, Peter Gregersen
  • Inhibition of autism spectrum disorder using decoy antigens to maternal brain-reactive antibodies
    Patent number: 11365243
    Abstract: Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: June 21, 2022
    Assignee: The Feinstein Institutes for Medical Research
    Inventors: Betty A. Diamond, Simone Mader, Lior Brimberg, Peter Gregersen
  • C1q AND HMGB1 FUSION PROTEINS AND USES THEREOF
    Publication number: 20220089644
    Abstract: Fusion proteins of C1q peptides and HMBG1 A-box or HMBG1 B-box, or C1q peptides and DWESY peptide are provided, and methods of use thereof.
    Type: Application
    Filed: October 12, 2021
    Publication date: March 24, 2022
    Inventor: Betty A. Diamond
  • C1q and HMGB1 fusion proteins and uses thereof
    Patent number: 11168112
    Abstract: Fusion proteins of C1q peptides and HMBG1 A-box or HMBG1 B-box, or C1q peptides and DWESY peptide are provided, and methods of use thereof.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: November 9, 2021
    Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
    Inventor: Betty A. Diamond
  • INHIBITION OF AUTISM SPECTRUM DISORDER USING DECOY ANTIGENS TO MATERNAL BRAIN-REACTIVE ANTIBODIES
    Publication number: 20200247880
    Abstract: Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies.
    Type: Application
    Filed: April 20, 2020
    Publication date: August 6, 2020
    Inventors: Betty A. Diamond, Simone Mader, Lior Brimberg, Peter Gregersen
  • Inhibition of autism spectrum disorder using decoy antigens to maternal brain-reactive antibodies
    Patent number: 10654919
    Abstract: Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: May 19, 2020
    Assignee: The Feinstein Institutes for Medical Research
    Inventors: Betty A. Diamond, Simone Mader, Lior Brimberg, Peter Gregersen
  • C1q AND HMGB1 FUSION PROTEINS AND USES THEREOF
    Publication number: 20190169232
    Abstract: Fusion proteins of C1q peptides and HMBG1 A-box or HMBG1 B-box, or C1q peptides and DWESY peptide are provided, and methods of use thereof.
    Type: Application
    Filed: January 31, 2019
    Publication date: June 6, 2019
    Applicant: THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
    Inventor: Betty A. Diamond
  • INHIBITION OF AUTISM SPECTRUM DISORDER USING DECOY ANTIGENS TO MATERNAL BRAIN-REACTIVE ANTIBODIES
    Publication number: 20190040121
    Abstract: Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies.
    Type: Application
    Filed: September 30, 2016
    Publication date: February 7, 2019
    Applicant: THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Betty A. Diamond, Simone Mader, Lior Brimberg
  • C1q peptides and uses thereof
    Patent number: 9758557
    Abstract: Isolated C1q peptides, fusion proteins and compositions comprising such and fusion proteins comprising are provided. Isolated fusion proteins comprising X4WX5YX6 as defined herein and compositions comprising such are also provided. Methods of treating autoimmune disorders are provided.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: September 12, 2017
    Assignee: The Feinstein Institute for Medical Research
    Inventor: Betty A. Diamond
  • Compounds and methods for treatment of systemic lupus erythematosus
    Patent number: 9096576
    Abstract: Small molecule compounds are provided for treating lupus as are methods of treating lupus using these compounds.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: August 4, 2015
    Assignee: The Feinstein Institute For Medical Research
    Inventors: Yousef Al-Abed, Betty A. Diamond
  • C1q PEPTIDES AND USES THEREOF
    Publication number: 20150104472
    Abstract: Isolated C1q peptides, fusion proteins and compositions comprising such and fusion proteins comprising are provided. Isolated fusion proteins comprising X4WX5YX6 as defined herein and compositions comprising such are also provided. Methods of treating autoimmune disorders are provided.
    Type: Application
    Filed: July 15, 2014
    Publication date: April 16, 2015
    Applicant: THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
    Inventor: Betty A. Diamond
  • COMPOUNDS AND METHODS FOR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20140309255
    Abstract: Small molecule compounds are provided for treating lupus as are methods of treating lupus using these compounds.
    Type: Application
    Filed: April 15, 2014
    Publication date: October 16, 2014
    Applicant: The Feinstein Institute For Medical Research
    Inventors: Yousef Al-Abed, Betty A. Diamond
  • Compounds and methods for treatment of systemic lupus erythematosus
    Patent number: 8741924
    Abstract: Small molecule compounds are provided for treating lupus as are methods of treating lupus using these compounds.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: June 3, 2014
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Yousef Al-Abed, Betty A. Diamond
  • METHODS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS USING HIV PROTEASE INHIBITORS
    Publication number: 20130317040
    Abstract: The present invention is directed to a method of treating systemic lupus erythematosus (SLE) in a subject comprising administering to the subject an amount of an HIV protease inhibitor effective to treat SLE. The present invention is also directed to a pharmaceutical product comprising an HIV protease inhibitor formulated in a pharmaceutically acceptable carrier, and a package insert providing instructions for the administration of the HIV protease inhibitor for the treatment of SLE. In addition, the present invention is directed to the use of an HIV protease inhibitor for the preparation of a medicament for the treatment of SLE.
    Type: Application
    Filed: December 21, 2011
    Publication date: November 28, 2013
    Applicant: The Feinstein Institute of Medical Research
    Inventors: Yousef Al-Abed, Betty A. Diamond
  • COMPOUNDS AND METHODS FOR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20130123299
    Abstract: Small molecule compounds are provided for treating lupus as are methods of treating lupus using these compounds.
    Type: Application
    Filed: May 6, 2011
    Publication date: May 16, 2013
    Applicant: The Feinstein Institute for Medical Research
    Inventors: Yousef Al-Abed, Betty A. Diamond
  • Peptides for detecting anti-double stranded DNA antibody and uses thereof
    Patent number: 7517657
    Abstract: The present invention provides a method for identifying a peptide which binds to an anti-double stranded DNA antibody. The present invention also provides a class of peptides identified by the method of the present invention which bind to anti-double stranded DNA antibodies and compositions containing these peptides. The present invention also provides methods for the diagnosis and treatment of systemic lupus erythematosus utilizing the peptides of the present invention.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: April 14, 2009
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Bruce D. Gaynor, Betty A. Diamond, Matthew D. Scharff, Philippe Valadon
  • Treatment of Cognitive Dysfunction in Lupus
    Publication number: 20070231316
    Abstract: Methods of preventing binding of an anti-double stranded (ds)-DNA antibody to a neuron in a mammal exhibiting or at risk for lupus-induced cognitive dysfunction are provided. Methods of inhibiting progression of cognitive dysfunction in a mammal exhibiting or at risk for lupus-induced cognitive dysfunction are also provided. Also provided are methods of inhibiting progression of cognitive dysfunction in a mammal exhibiting or at risk for lupus-induced cognitive dysfunction. Additionally, methods of inhibiting progression of cognitive dysfunction in a mammal exhibiting or at risk for lupus-induced cognitive dysfunction are provided. Further provided are methods of inducing cognitive dysfunction in a mammal, and nonhuman mammal treated with a DNA mimotope in such a manner to induce antibodies that bind to ds-DNA and an NR2 subunit of a neuron in the mammal, then, after the antibodies are induced, treated to temporarily open the blood brain barrier.
    Type: Application
    Filed: October 5, 2004
    Publication date: October 4, 2007
    Inventors: Betty Diamond, Bruce Volpe
  • Methods and compositions for identification of antigen-specific B cell populations
    Publication number: 20050287607
    Abstract: Provided are compositions and methods for identifying, enumerating and isolating B cells that react to a particular antigen. Included are tetrameric antigen-avidin complexes not comprising an MHC molecule, kits for producing the complexes, and reagents for diagnosing an autoimmune disease or monitoring progression of an autoimmune disease comprising the complexes. Also provided are B cells comprising the complexes and methods of using the complexes for: labeling a B cell reactive to a specific antigen, isolating a B cell reactive to a specific antigen from a mixture of B cells reactive to more than one antigen, quantifying B cells reactive to a specific antigen in a mixture of B cells reactive to more than one antigen, measuring immunity in a mammal characterized by the presence of B cells reactive to a specific antigen, and monitoring a disease in a mammal or determining whether a mammal has a disease characterized by the presence of B cells reactive to a specific antigen.
    Type: Application
    Filed: January 4, 2005
    Publication date: December 29, 2005
    Inventors: Betty Diamond, Jeffrey Newman
  • Peptides for the treatment and diagnosis of systemic lupus erythematosus
    Publication number: 20050214852
    Abstract: The present invention provides a method for identifying a peptide which binds to an anti-double stranded DNA antibody. The present invention also provides a class of peptides identified by the method of the present invention which bind to anti-double stranded DNA antibodies and compositions containing these peptides. The present invention also provides methods for the diagnosis and treatment of systemic lupus erythematosus utilizing the peptides of the present invention.
    Type: Application
    Filed: May 13, 2005
    Publication date: September 29, 2005
    Inventors: Bruce Gaynor, Betty Diamond, Matthew Scharff, Philippe Valadon
  • Peptides for the treatment and diagnosis of systemic lupus erythematosus
    Patent number: 6932970
    Abstract: The present invention provides a method for identifying a peptide which binds to an anti-double stranded DNA antibody. The present invention also provides a class of peptides identified by the method of the present invention which bind to anti-double stranded DNA antibodies and compositions containing these peptides. The present invention also provides methods for the diagnosis and treatment of systemic lupus erythematosus utilizing the peptides of the present invention.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: August 23, 2005
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Bruce D. Gaynor, Betty A. Diamond, Matthew D. Scharff, Philippe Valadon