Patents by Inventor Betty A. Diamond

Betty A. Diamond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides which bind to anti-double stranded DNA antibody
    Patent number: 6001964
    Abstract: The present invention provides a method for identifying a peptide which binds to an anti-double stranded DNA antibody. The present invention also provides a class of peptides identified by the method of the present invention which bind to anti-double stranded DNA antibodies and compositions containing these peptides. The present invention also provides methods for the diagnosis and treatment of systemic lupus erythematosus utilizing the peptides of the present invention.
    Type: Grant
    Filed: September 20, 1995
    Date of Patent: December 14, 1999
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Bruce D. Gaynor, Betty A. Diamond, Matthew D. Scharff, Philippe Valadon
  • Hybridoma-producing NSO myeloma cell line
    Patent number: 5565337
    Abstract: This invention relates to an NSO myeloma cell line which has increased fusion frequency, and to a method of producing said cell line. The NSO cell line of the invention, when fused with B cells, produces monoclonal antibody-secreting hybridoma which has increased resistance to death. In addition, the monoclonal antibodies secreted by said hybridomas have increased affinity for foreign antigens and for autoantigens.
    Type: Grant
    Filed: August 23, 1994
    Date of Patent: October 15, 1996
    Assignee: Albert Einstein College of Medicine of Yeshiva University, a Division of Yeshiva University
    Inventors: Betty A. Diamond, Subhransu Ray
  • Monoclonal antibodies reactive with shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus
    Patent number: 4692416
    Abstract: The invention relates to monoclonal anti-idiotypic antibodies to human anti-DNA antibodies. Monoclonal, anti-idiotypic antibodies are produced using hybridoma technology. The antibodies are used as diagnostic reagents in methods to determine the presence of anti-native DNA antibodies in serum from patients suspected of having systemic lupus erythematosus.
    Type: Grant
    Filed: November 16, 1983
    Date of Patent: September 8, 1987
    Assignee: Yeshiva University
    Inventor: Betty A. Diamond
  • Method for removal of human antibodies to native DNA from serum
    Patent number: 4690905
    Abstract: The invention relates to monoclonal anti-idiotypic antibodies to human anti-DNA antibodies. Monoclonal, anti-idiotypic antibodies are produced using hybridoma technology. The antibodies are used as diagnostic reagents in methods to determine the presence of anti-native DNA antibodies in serum from patients suspected of having systemic lupus erythematosus, and as therapeutic reagents in methods to remove the anti-native DNA antibodies from the serum of patients with systemic lupus erythematosus.
    Type: Grant
    Filed: November 30, 1983
    Date of Patent: September 1, 1987
    Assignee: Albert Einstein College of Medicine of Yeshiva University, a division of Yeshiva University
    Inventor: Betty A. Diamond