Abstract: A display system includes a segmented light source including a plurality of separately controlled segments to emit light, optics to direct the light, and a spatial light modulator (SLM) to modulate the light from the light source, wherein the light from one or more of the plurality of segments from the segmented light source are directed to the SLM through the optics, such that spatial mapping from the segments to the SLM is maintained.

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36?, IL-36?, and/or IL-36?, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.

Abstract: The present invention provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36?, IL-36?, and/or IL-36?, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.

Abstract: Carefully coordinated patches having camouflaging and/or benefit properties can be formed for application to a desired region of human skin. The patches include a flexible film having a first, adhesive, outwardly facing major surface and a second outwardly facing surface which is textured to correspond to skin covered by the patch during use; wherein the flexible film further comprises at least one pigmented region and at least one region adapted to modify one or more optical properties selected from the group consisting of light transmission, light reflection, and light absorption. Methods of custom use of such patches may include 3D printing processes.

Abstract: Disclosed herein are systems and methods for implementing virtualized Road-Side Units (vRSUs). Edge computing devices implementing one or more vRSU services may associate vehicles with identifiers that are based at least in part upon the locations of the vehicles. The locations may be established by location services of the edge computing devices, based upon communication received from the vehicles via wireless cellular communication links. The edge computing devices may then process infrastructure information that they receive, for distribution to the vehicles, at the vRSU services. Based upon the processing of infrastructure information at the vRSU services, messages may be generated for transmission to the vehicles (e.g., over the wireless cellular communication links), with the messages carrying information based upon the infrastructure information, such as in the form of safety messages and/or information messages.

Abstract: A transdermal delivery device includes a film having first and second outwardly facing major surfaces; at least one liquid reservoir contained within the film; at least one microfluidic channel having a transverse dimension between about 100 nm and 0.5 mm disposed within the film and in fluid communication with the at least one liquid reservoir; and at least one outlet port associated with at least one microneedle operatively connected to the first outwardly facing major surface of the film in fluid communication with the at least one microfluidic channel.

Abstract: A dermal delivery device includes a film having first and second outwardly facing major surfaces; at least one liquid reservoir contained within the film; at least one microfluidic channel having a transverse dimension between about 100 nm and 0.5 mm disposed within the film and in fluid communication with the at least one liquid reservoir; and at least one outlet port operatively connected to the first outwardly facing major surface of the film in fluid communication with the at least one microfluidic channel.

Abstract: A transdermal delivery device includes a film having first and second outwardly facing major surfaces; at least one liquid reservoir contained within the film; at least one microfluidic channel having a transverse dimension between about 100 nm and 0.5 mm disposed within the film and in fluid communication with the at least one liquid reservoir; and at least one outlet port associated with at least one microneedle operatively connected to the first outwardly facing major surface of the film in fluid communication with the at least one microfluidic channel.

Abstract: Systems and methods for dynamic maximum transmission unit determination are disclosed. For example, one or more triggering events may be detected to initiate determining whether to adjust transmission unit sizing for data transmission between devices. Received signal strength indicator (RSSI) values may be exchanged between the devices and those RSSI values may be utilized to determine a strength of a communication signal between devices. When the RSSI values are low, the communication signal strength may be weak and the devices may adjust the transmission unit size to be larger. In other examples when the RSSI values are high, the communication signal strength may be strong and the devices may adjust the transmission unit size to be smaller.

Abstract: An array of differing microneedles can be accurately achieved including a film having first and second, outwardly facing major surfaces. The first, outwardly facing major surface has a plurality of stratum corneum piercing microneedles extending therefrom, and the plurality of microneedles includes a plurality of first microneedles having a first benefit agent and a plurality of second microneedles having a second benefit agent.

Abstract: A Foundational Framework (“the Framework”) may refer to an apparatus that connects a multiplicity of potentially very complex components, each of which produce different types of information related to financial forecast, while maintaining a distributed and federated model to allow high autonomy to each component. The innovative Framework provides a unified operation of lifecycle of every component and allows the production of unlimited types of forecasts of different dimensions and for different purposes using a common tool that is responsible of coordinating and running the sequence of components for the user's needs.

Abstract: An array of differing microneedles can be accurately achieved including a film having first and second, outwardly facing major surfaces. The first, outwardly facing major surface has a plurality of stratum corneum piercing microneedles extending therefrom, and the plurality of microneedles includes a plurality of first microneedles having a first benefit agent and a plurality of second microneedles having a second benefit agent.

Abstract: A set of at least two substantially rectangular pillows sold as a bundle for use in locations that accommodate a periodic changing or replacement of clientele, such as hotels, motels, hospitals, military barracks, college dormitories, and the like. A first substantially rectangular pillow has a longitudinal upper border having a proximal end and a distal end and a longitudinal lower border parallel to the longitudinal upper border, the longitudinal lower border having a proximal end and a distal end, each of the ends being oppositely disposed to the longitudinal upper border proximal end and the longitudinal upper border distal end, respectively. A first side border is connected to the proximal ends of the longitudinal upper border and the longitudinal lower border. A second side border is connected to the distal ends of the longitudinal upper border and the longitudinal lower border.

Abstract: A system includes an applicator mask having an applicator surface having a three-dimensional shape corresponding to the isolated body part; and at least one membrane releasably disposed on the applicator surface and having an outer surface in facing relation with the applicator surface and inner adhesive surface opposite thereof. The membrane includes one or more benefit agents disposed in one or more treatment zones.

Abstract: Carefully coordinated patches having camouflaging and/or benefit properties can be formed for application to a desired region of human skin. The patches include a flexible film having a first, adhesive, outwardly facing major surface and a second outwardly facing surface which is textured to correspond to skin covered by the patch during use; wherein the flexible film further comprises at least one pigmented region and at least one region adapted to modify one or more optical properties selected from the group consisting of light transmission, light reflection, and light absorption. Methods of custom use of such patches may include 3D printing processes.

Abstract: A system includes an applicator mask having an applicator surface having a three-dimensional shape corresponding to the isolated body part; and at least one membrane releasably disposed on the applicator surface and having an outer surface in facing relation with the applicator surface and inner adhesive surface opposite thereof. The membrane includes one or more benefit agents disposed in one or more treatment zones.

Abstract: A rectangular bed pillow has a longitudinal upper border having a proximal end and a distal end and a longitudinal lower border parallel to the longitudinal upper border. A first side border is connected to the proximal ends of the upper border and the lower border. A second side border is connected to the distal ends of the upper border and the lower border. A longitudinal partition is disposed parallel to the upper border and the lower border extending between the first and second side borders, forming an upper portion and a lower portion of the pillow. A first quantity of filling material fills the upper portion of the pillow and a second quantity of filling material fills the lower portion of the pillow, so the upper portion of the pillow has a first thickness and the lower portion of the pillow has a second thickness.

Abstract: A wireless power transfer circuit can include an interphase transformer operatively coupled to a receiver coil, a rectifier, and a load. The receiver coil can be configured to have an alternating current induced therein by a transmitter coil. The interphase transformer can be configured to deliver a current to the load that is twice the current induced in the receiver coil, and the rectifier can be configured to rectify the current delivered to the load. The interphase transformer may be constructed with a center tapped winding structure or a bifilar winding structure, and may be constructed as a planar transformer. The rectifier may be made up of diodes (which may be Schottky diodes) or may be a synchronous rectifier comprised of switching devices such as MOSFETs.

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36?, IL-36?, and/or IL-36?, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.

Abstract: Methods, systems and computer program products for managing content objects in a content management system. A metadata template is assigned to a content object of the content management system. Extensible metadata pertaining to the content object is allocated in accordance with the assigned metadata template. Various operations over the content object result in population of the allocated extensible metadata. When the content object is subjected to a workflow, the execution flow and/or the form of responses associated with execution of the workflow are informed by the populated extensible metadata. A single content object can take on an association with multiple sets of extensible metadata and each set of extensible metadata can take on association with a respective workflow.