Patents by Inventor Biao He

Biao He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10419951
    Abstract: A method for combining with a minimum isolation bandwidth includes: determining an insertion loss and an isolation between ports of a combiner; calculating a total isolation bandwidth of an isolation band in the combiner according to the insertion loss and the isolation between ports; determining guard bandwidths adjacent to the isolation band in combined systems, the combined systems being at least two communication systems combined by the combiner; and, calculating an actual isolation bandwidth of the combiner according to the guard bandwidths of the combined systems and the total isolation bandwidth.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: September 17, 2019
    Assignee: CHINA UNITED NETWORK COMMUNICATIONS GROUP COMPANY LIMITED
    Inventors: Guixin Pan, Xiaoming Huang, Wei Li, Biao He, Jun Yan, Junbin Mo, Huiming Ge, Yuchen Shi, Jianquan Wang, Qingyu Cai
  • Publication number: 20190216918
    Abstract: The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/US/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to rMuVIowa/US/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuV?SH) and/or incapable of expressing the V protein (rMuV?V).
    Type: Application
    Filed: March 13, 2019
    Publication date: July 18, 2019
    Inventors: Biao He, Steven A. Rubin
  • Patent number: 10329585
    Abstract: The present invention includes the Paramyxovirus Parainfluenza Virus 5 (PIV5) as an oncolytic agent for treating various cancers, including, but not limited to breast cancer, lung cancer and melanoma. PIV5 oncolytic agents include both wild type PIV5 and various recombinant PIV5 constructs. Recombinant PIV5 constructs may include PIV5 lacking the conserved C-terminus of the V protein (PIV5V?C), PIV5 with mutations in the N-terminus of the V/P protein (PIV5CPI?), and PIV5 expressing MDA-7/IL-24 (rPIV5-MDA7), rPIV5-V/P-CPI?, rPIV5-CPI+, rPIV5-Rev, rPIV5-RL, rPIV5-P-S157A, rPIV5-P-S308A, rPIV5-L-A1981D, rPIV5-F-5443P, rPIV5-MDA7, rPIV5?SH-CPI?, or rPIV5?SH-Rev. Also included are methods of making and using such oncolytic agents and compositions including such oncolytic agents.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: June 25, 2019
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventor: Biao He
  • Publication number: 20190161538
    Abstract: Antibodies that specifically bind to a Sonic Hedgehog (Shh) polypeptide, or an antigen binding fragment thereof, are provided. Also provided are methods of treating an individual for cancer using the Shh polypeptide antibodies. Methods of analyzing a tissue sample for cell-surface expression of a full-length Shh polypeptide are also provided.
    Type: Application
    Filed: June 28, 2017
    Publication date: May 30, 2019
    Applicant: The Regents of the University of California
    Inventors: David M. Jablons, Bhairavi Tolani, Biao He, Etienne Giroux-Leprieur
  • Publication number: 20180372507
    Abstract: An information sharing method for a smart electricity meter, the smart electricity meter and an acquisition router are provided. Multiple Internet Protocol version 6 (IPv6) addresses are allocated to the smart electricity meter; the smart electricity meter specifies the corresponding IPv6 address according to a type of information to initiate a Transmission Control Protocol (TCP)/Internet Protocol (IP) connection to the acquisition router; and the acquisition router searches for routing IPv6 addresses with same rules as rules of the IPv6 address according to the IPv6 address, and sends the information to destination addresses specified by the information through the routing IPv6 addresses.
    Type: Application
    Filed: July 11, 2016
    Publication date: December 27, 2018
    Inventors: Wenpeng Luan, Biao He, Fengquan Zhou, Peng Wang, Daqing Xu, Zhanguo Zhang, Xuezheng Xie
  • Publication number: 20180351485
    Abstract: A method and circuit for controlling or starting a U-shape single phase synchronous permanent magnetic motor (U-SPSPM motor) having a rotor and a stator and coupled to a single phase alternating current (AC) power source through a switch, including estimating back electromotive force (back-EMF) of the motor based on an observer model with inputs indicative of the measured signals, and triggering the switch to supply power to the motor based on the estimates of the back-EMF.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventors: KEVIN J. FITZPATRICK, BIAO HE, QIANG MEI, YING XIAO
  • Patent number: 10075110
    Abstract: A method and circuit for controlling or starting a U-shape single phase synchronous permanent magnetic motor (U-SPSPM motor) having a rotor and a stator and coupled to a single phase alternating current (AC) power source through a switch, including estimating back electromotive force (back-EMF) of the motor based on an observer model with inputs indicative of the measured signals, and triggering the switch to supply power to the motor based on the estimates of the back-EMF.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: September 11, 2018
    Assignee: Whirlpool Corporation
    Inventors: Kevin J. Fitzpatrick, Biao He, Qiang Mei, Ying Xiao
  • Publication number: 20180044644
    Abstract: Compositions, methods of use and methods of manufacture are provided for PIV5-based amplifying VLP (AVLP) that can deliver an expressible heterologous nucleotide sequence in target cells without producing progeny, and which demonstrate useful safety and therapeutic efficacy in multiple animal and human health applications, such as vaccination, gene therapy and cancer therapy.
    Type: Application
    Filed: April 28, 2016
    Publication date: February 15, 2018
    Applicant: University of Georgia Research Foundation, Inc.
    Inventor: Biao He
  • Publication number: 20180002761
    Abstract: The present invention provides methods for providing a prognosis for lung adenocarcinoma, using a panel of eight molecular markers that are differentially expressed in lung adenocarcinoma.
    Type: Application
    Filed: March 8, 2017
    Publication date: January 4, 2018
    Inventors: David M. JABLONS, Dan J. RAZ, Biao HE
  • Patent number: 9840470
    Abstract: The present disclosure provides compositions, pharmaceutical preparations and methods for the diagnosis and treatment of cancers expressing a GLI polypeptide. The disclosed compositions and pharmaceutical preparations may comprise one or more pyrazolyl-containing compounds, or an analog or derivative thereof.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: December 12, 2017
    Assignee: The Regents of the University of California
    Inventors: Biao He, Michael Mann, David M. Jablons
  • Publication number: 20170353875
    Abstract: A method for combining with a minimum isolation bandwidth includes: determining an insertion loss and an isolation between ports of a combiner; calculating a total isolation bandwidth of an isolation band in the combiner according to the insertion loss and the isolation between ports; determining guard bandwidths adjacent to the isolation band in combined systems, the combined systems being at least two communication systems combined by the combiner; and, calculating an actual isolation bandwidth of the combiner according to the guard bandwidths of the combined systems and the total isolation bandwidth.
    Type: Application
    Filed: August 22, 2017
    Publication date: December 7, 2017
    Applicant: CHINA UNITED NETWORK COMMUNICATIONS GROUP COMPANY LIMITED
    Inventors: Guixin PAN, Xiaoming HUANG, Wei LI, Biao HE, Jun YAN, Junbin MO, Huiming GE, Yuchen SHI, Jianquan WANG, Qingyu CAI
  • Publication number: 20170327845
    Abstract: The present invention includes the Paramyxovirus Parainfluenza Virus 5 (PIV5) as an oncolytic agent for treating various cancers, including, but not limited to breast cancer, lung cancer and melanoma. PIV5 oncolytic agents include both wild type PIV5 and various recombinant PIV5 constructs. Recombinant PIV5 constructs may include PIV5 lacking the conserved C-terminus of the V protein (PIV5V?C), PIV5 with mutations in the N-terminus of the V/P protein (PIV5CPI?), and PIV5 expressing MDA-7/IL-24 (rPIV5-MDA7), rPIV5-V/P-CPI?, rPIV5-CPI+, rPIV-Rev, rPIV5-RL, rPIV5-P-S157A, rPIV5-P-S308A, rPIV5-L-A1981D, rPIV5-F-5443P, rPIV5-MDA7, rPIV5?SH-CPI?, or rPIV5?SH-Rev. Also included are methods of making and using such oncolytic agents and compositions including such oncolytic agents.
    Type: Application
    Filed: June 30, 2017
    Publication date: November 16, 2017
    Inventor: Biao He
  • Publication number: 20170288581
    Abstract: A method and circuit for controlling or starting a U-shape single phase synchronous permanent magnetic motor (U-SPSPM motor) having a rotor and a stator and coupled to a single phase alternating current (AC) power source through a switch, including estimating back electromotive force (back-EMF) of the motor based on an observer model with inputs indicative of the measured signals, and triggering the switch to supply power to the motor based on the estimates of the back-EMF.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 5, 2017
    Inventors: KEVIN J. FITZPATRICK, BIAO HE, QIANG MEI, YING XIAO
  • Publication number: 20170232098
    Abstract: The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/US/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to rMuVIowa/US/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuV?SH) and/or incapable of expressing the V protein (rMuV?V).
    Type: Application
    Filed: April 28, 2017
    Publication date: August 17, 2017
    Inventor: Biao He
  • Patent number: 9732358
    Abstract: The present invention includes the Paramyxovirus Parainfluenza Virus 5 (PIV5) as an oncolytic agent for treating various cancers, including, but not limited to breast cancer, lung cancer and melanoma. PIV5 oncolytic agents include both wild type PIV5 and various recombinant PIV5 constructs. Recombinant PIV5 constructs may include PIV5 lacking the conserved C-terminus of the V protein (PIV5VAC), PIV5 with mutations in the N-terminus of the V/P protein (PIV5CPI?), and PIV5 expressing MDA-7/IL-24 (rPIV5-MDA7), rPIV5-V/P-CPI?, rPIV5-CPI+, rPIV-Rev, rPIV5-RL, rPIV5-P-S157A, rPIV5-P-S308A, rPIV5-L-A1981D, rPIV5-F-S443P, rPIV5-MDA7, rPIV5ASH-CPI?, or rPIV5ASH-Rev. Also included are methods of making and using such oncolytic agents and compositions including such oncolytic agents.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: August 15, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventor: Biao He
  • Patent number: 9729093
    Abstract: A method for controlling a U-shape single phase synchronous permanent magnetic motor having a rotor and a stator and coupled to a single phase alternating current (AC) power source through a switch includes estimating back-electromotive force and the position of the rotor based on a voltage feedback signal, a current feedback signal, and a phase feedback signal indicative of a zero-crossing of the single phase AC power source. Once the speed and position of the rotor are determined, a controller can trigger a switch to supply power to the motor.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: August 8, 2017
    Assignee: Whirlpool Corporation
    Inventors: Kevin J. Fitzpatrick, Biao He, Qiang Mei, Ying Xiao
  • Patent number: 9725424
    Abstract: Disclosed in the present invention are 4-(5-amino-6-hydroxybenzoxazol-2-yl)ammonium benzoate shown in formula (I) and the preparation method and use thereof. The preparation method comprises: fully reacting 4-(5-amino-6-hydroxybenzoxazol-2-yl)benzoic acid shown in formula (II) or 4-(5-amino-6-hydroxybenzoxazol-2-yl)carboxamide benzoate, as a raw material, with ammonia in an aqueous solvent, and directly heating the obtained reaction liquid to remove excess ammonia, so as to obtain 4-(5-amino-6-hydroxybenzoxazol-2-yl)ammonium benzoate. The mass of the 4-(5-amino-6-hydroxybenzoxazol-2-yl)ammonium benzoate (ABAA) prepared in the present invention can reach a polymer grade (where the purity is above 99.
    Type: Grant
    Filed: February 9, 2013
    Date of Patent: August 8, 2017
    Assignees: ZHEJIANG UNIVERSITY OF TECHNOLOGY, YANCHENG DRAGON CHEMICAL CO., LTD.
    Inventors: Ningren Jin, Biao He, Jing Jin
  • Publication number: 20170170759
    Abstract: A method for controlling a U-shape single phase synchronous permanent magnetic motor having a rotor and a stator and coupled to a single phase alternating current (AC) power source through a switch includes estimating back-electromotive force and the position of the rotor based on a voltage feedback signal, a current feedback signal, and a phase feedback signal indicative of a zero-crossing of the single phase AC power source. Once the speed and position of the rotor are determined, a controller can trigger a switch to supply power to the motor.
    Type: Application
    Filed: December 15, 2015
    Publication date: June 15, 2017
    Inventors: KEVIN J. FITZPATRICK, BIAO HE, QIANG MEI, YING XIAO
  • Patent number: 9649371
    Abstract: The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/us/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to MuVIowa/us/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuV?SH) and/or incapable of expressing the V protein (rMuV?V).
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: May 16, 2017
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventor: Biao He
  • Publication number: 20170067080
    Abstract: The present invention provides safe, stable, efficacious, and cost-effective vaccines based on viral expression vectors that include a parainfluenza virus 5 (PIV5) genome including a heterologous nucleotide sequence expressing a heterologous polypeptide.
    Type: Application
    Filed: October 18, 2016
    Publication date: March 9, 2017
    Inventor: Biao He