Abstract: Disclosed herein is an anti-tumor pharmaceutical composition based on immune checkpoint blockade and use thereof. The anti-tumor pharmaceutical composition comprises: paroxetine hydrochloride, and a T-cell enhancer, wherein the T-cell enhancer is at least one of vitamin E and thymosin. Through a series of in vitro and in vivo experiments, cannabidiol and paroxetine hydrochloride were first found to be capable of effectively reducing the expression of PD-L1 on the tumor cell membrane, thereby blocking the PD-1/PD-L1 signaling pathway and enhancing the ability of T cells to kill tumor cells. The T-cell enhancer added on this basis can further increase the quantity and activity of T cells, significantly increase the killing ability of T cells after immunosuppression is relieved, and greatly improve the anti-tumor effect of the drug.

Abstract: A robotic system for use in installing final trim and assembly part includes an auto-labeling system that combines images of a primary component, such as a vehicle, with those of computer based model, where feature based object tracking methods are used to compare the two. In some forms a camera can be mounted to a moveable robot, while in other the camera can be fixed in position relative to the robot. An artificial marker can be used in some forms. Robot movement tracking can also be used. A runtime operation can utilize a deep learning network to augment feature-based object tracking to aid in initializing a pose of the vehicle as well as an aid in restoring tracking if lost.

Abstract: A multispectral light field imaging system includes a primary lens, a microlens array, a first relay lens, a dichroic lens, a second relay lens, a third relay lens, a first image sensor, a first filter, a second image sensor and a second filter, wherein the microlens array is located at an image plane of the primary lens; the first relay lens together with the second relay lens and the third relay lens forms a 1:1 relay lens group imaging system on a spectral band 1 light path and a spectral band 2 light path respectively; the dichroic lens forms an included angle of 45° with a light axis; the first image sensor is located at a focal plane of the second relay lens, and the second image sensor is located at a focal plane of the third relay lens.

Abstract: The present disclosure provides an internal pressure adjustment structure for a multi-chamber inflatable product, which can simplify the user's air pressure adjustment operation and improve the user's experience. The internal pressure adjustment structure may include at least one regulating valve positioned between at least two air chambers of an inflatable product and an inflation and deflation assembly fluidly coupled to at least one of the at least two air chambers.

Abstract: An impact tool includes a motor including or connected to a drive shaft for outputting power and is rotatable about a first axis, an impact assembly including a main shaft and a spring sleeved on the main shaft, a transmission assembly for transmitting the power output by the drive shaft to the main shaft, a main shaft bearing for supporting the main shaft, and a second bearing for supporting the drive shaft. The projections of the second bearing, the main shaft bearing and the spring on a reference plane perpendicular to the up and down direction have an overlapping region.

Abstract: An air leakage prevention adjusting structure of a mechanical pump is provided. The adjusting structure may be applied to a multi-channel pump. The multi-channel pump may comprise a body, an air pump assembly and a channel switching structure which are arranged in the body, and a panel matched on the body. The adjusting structure may be matched on the panel and may comprise a channel selection knob, a turntable and a power switch. The channel selection knob may be rotatably arranged on the panel. The turntable may be arranged in the body. The upper end of the turntable may be connected with the channel selection knob, and the lower end of the turntable may be matched with the channel switching assembly. A convex edge and a notch may be arranged on the turntable. A button for controlling the on-off of a power supply is arranged on the power switch, and is selectively matched with the convex edge and the notch of the turntable.

Abstract: A filter medium contamination detection structure may comprise a filter element and a prompt assembly. The prompt assembly may comprise a first pressure sensor, which may comprise a signal output end, and a second pressure sensor, which may comprise a signal output end. The first pressure sensor may be connected to a water inlet of the filter element, and the second pressure sensor may be connected to a water outlet of the filter element or outside air. The signal output ends of the first pressure sensor and the second pressure sensor may be connected to a signal input end of a controller. When the filter element is dirty, a pressure at the water inlet end may increase or a pressure at the water outlet end may decrease, and the difference between the first sensor and the second pressure sensor may increase.

Abstract: A multispectral light field imaging system includes a primary lens, a microlens array, a first relay lens, a dichroic lens, a second relay lens, a third relay lens, a first image sensor, a first filter, a second image sensor and a second filter, wherein the microlens array is located at an image plane of the primary lens; the first relay lens together with the second relay lens and the third relay lens forms a 1:1 relay lens group imaging system on a spectral band 1 light path and a spectral band 2 light path respectively; the dichroic lens forms an included angle of 45° with a light axis; the first image sensor is located at a focal plane of the second relay lens, and the second image sensor is located at a focal plane of the third relay lens.

Abstract: A robotic system capable of being trained with a plurality of images that are synthetically augmented from an initial image data set includes a training system toward that end. An image augmentation system includes in one form a neural network trained to generate synthetic images using a generative adversarial network which includes the ability to synthesize images having various poses with adjustments to image parameters such as light and color among potential others. In another form the image augmentation system includes a set of images projected or transformed from its original pose to a number of different poses using an affine transform, and the ability to progress across an entire dimensional space of anticipated robot movements which produce various potential poses.

Abstract: The present application proposes a method and a system for constructing a data command frame for remote reservation control, by setting a first byte representing a reserved working time start point, a second byte representing one-time working duration, a third byte representing the reservation status of a whole working cycle, the whole working cycle is divided into several time units, the third byte includes several bits corresponding to several time units, and assigns the value of each bit to determine whether the time units corresponding to each bit is reserved as working time; then combining the first byte, the second byte and the third byte to construct data command frame, and sending the command frames to device to realize remote control. This method enables remote reservation setting on the management of places like spa pools, which is safer and more convenient for spa management staff, and can greatly improve working efficiency and reduce the probability of error.

Abstract: A contamination prompt structure for a filter medium may comprise a filter element and a prompt assembly. The prompt assembly may have a movable part. One end of the movable part may be in communication with one of a water inlet of the filter element, or a water outlet of the filter element, and the other end of the movable part may be in communication with the other one of the water inlet of the filter element, the water outlet of the filter element, or outside air. When the filter element is in a contaminated state, a rise of pressure at the water inlet or a drop of pressure at the water outlet may drive the movable part to move to send a prompt for a user to replace the filter element.

Abstract: An inspection device for use in a fluid container having at least an opening includes a housing sized to fit through the opening. The housing has at least two fluid flow channels extending therethrough, each having an inlet and an outlet, and a pump maintained in the housing within each fluid flow channel. The pumps are selectively controlled to maneuver the housing within the fluid container. The inspection device continues with a method of in-situ inspection of a container having at least one opening to receive a fluid, that includes up-loading a virtual model of the container into a computer, inserting the device into the container, generating a position signal by the device and receiving the position signal on a computer. A virtual image of the device in the virtual model of the container is generated to determine an actual position of the device within the container.

Abstract: An impact tool includes an impact assembly and a housing. The impact assembly is used for applying an impact force to an output shaft and includes a main shaft driven by a drive shaft, an impact block connected to the main shaft, and a hammer anvil mating with and struck by the impact block. A motor is at least partially accommodated in the housing. A length L from a rear end of the housing to a front end of the output shaft is greater than or equal to 78 mm and less than or equal to 97 mm and an outer circumferential diameter D of the housing is less than or equal to 60 mm.

Abstract: A ducted air conditioner includes a housing, a heat-retaining and drainage assembly, a fan assembly and an air conditioning device. The heat-retaining and drainage assembly is disposed in the housing, and includes a first heat-retaining member and a second heat-retaining member. The first heat-retaining member includes a first dividing plate. The second heat-retaining member is stacked with the first heat-retaining member, the second heat-retaining member includes a second dividing plate connected to the first heat-retaining member. An inner space of the housing is divided to a first cavity and a second cavity, an arrangement direction of the first cavity and the second cavity is perpendicular to a stacking direction of the first heat-retaining member and the second heat-retaining member. The fan assembly is disposed in the first cavity. The air conditioning device is disposed in the second cavity, and located between the first heat-retaining member and the second heat-retaining member.

Abstract: An independent display frame interpolation circuit includes a System-on-a-Chip and an independent display chip. The System-on-a-Chip is configured to generate first data based on first content to be displayed, and send the first data to the independent display chip in a case that a target TE signal sent by the independent display chip is received, where a frame rate of the first data is smaller than a frame rate of the first content. The independent display chip is configured to perform frame interpolation processing on the first data to obtain second data, and a frame rate of the second data is greater than or equal to the frame rate of the first content.

Abstract: A robotic system for use in installing final trim and assembly part includes an auto-labeling system that combines images of a primary component, such as a vehicle, with those of computer based model, where feature based object tracking methods are used to compare the two. In some forms a camera can be mounted to a moveable robot, while in other the camera can be fixed in position relative to the robot. An artificial marker can be used in some forms. Robot movement tracking can also be used. A runtime operation can utilize a deep learning network to augment feature-based object tracking to aid in initializing a pose of the vehicle as well as an aid in restoring tracking if lost.

Abstract: A low-loss motor may include a casing, a rear cover, and a rotatable shaft. The rotatable shaft may have a first end contacting the rear cover and a second end. An end face of the first end of the rotatable shaft may have a first shape and a contact surface of the rear cover may have a second shape, the second shape being different than the first shape.

Abstract: A chuck device includes a connecting mechanism and a locking mechanism, where the locking mechanism includes a driving portion, a first locking portion and a second locking portion, where the first locking portion at least partially extends into a first receiving portion; and the second locking portion is rotatably connected to the first receiving portion through a second shaft. When the locking mechanism is in a first state, the second locking portion rotates along a first direction to drive a sleeve to bias against a biasing element and release a limitation on the first locking portion.

Abstract: An inflatable product includes an integrated axial-flow pump which produces a high rate of inflation. The pump includes a cover mounted to a body of the pump and selectively configurable between open and closed positions. In the open position, air is allowed to flow between the inflatable chamber and the ambient air through the pump body. When the cover is closed, the air chamber of the inflatable product is sealed with respect to the ambient air such that air is retained within the inflatable chamber when inflated. A power switch is positioned to be deactivated by the cover when the cover is mounted to the body of the pump, such that replacement of the cover during inflation or deflation of the inflatable product automatically deactivates the pump.