Abstract: The present disclosure relates to methods of treating cancer by administering a compound, which is a Fibroblast Growth Factor Receptor (FGFR) inhibitor, in combination with a Kirsten rat sarcoma (KRAS) inhibitor.

Abstract: An example circuit includes a substrate having a surface and electrically conductive lines. The electrically conductive lines extend in a direction substantially parallel to the surface and substantially orthogonal to a virtual centerline. The circuit also includes first and second instances of a driver device having respective first and second sides, and respective line outputs. The line outputs are arranged along the first side of the respective instance of the driver device, and the respective first side of each of the first and second instances of the driver device are nearer the virtual centerline than the second side thereof. The line outputs of the first instance of the driver device are coupled to a first set of the electrically conductive lines, and the line outputs of the second instance of the driver device are coupled to a second set of the electrically conductive lines.

Abstract: A system for performing a coordinated transaction is disclosed, involving a digital asset transaction performed on a blockchain and a payment transaction performed at a payment processing system. The system comprises a blockchain subsystem arranged to interface with the blockchain and to execute a main workflow process including the digital asset transaction and an interface to the payment processing system. A plurality of interface operations are provided which can be invoked by the main workflow process. Each operation is arranged to communicate via the interface with the payment processing system to control execution of a respective stage of the payment processing transaction at the payment processing system; and to maintain on the blockchain minor transaction data tracking a status of the payment processing transaction at the respective stage. The system is further configured to synchronize execution of the digital asset transaction with the payment transaction using the interface operations.

Abstract: Disclosed herein is a method for generating an image using an electronic device having a color camera, comprising: activating the color camera and a camera application on the electronic device; displaying, through the camera application, a preview image generated by the color camera; determining, automatically, whether the preview image includes an image of a first object; displaying, through the camera application in response to a determination that the preview image includes the image of the first object, a first image generated by the color camera, the first image including a color region corresponding to the first object and a grayscale region corresponding to objects that are not the first object; and displaying, through the camera application in response to a determine that the preview image does not include any image of the first object, a second image generated by the color camera, the second image is a grayscale image.

Abstract: Provided are an on-board data processing method, an electronic device and a storage medium, which relates to a field of artificial intelligence technology, and in particular, to fields of Internet of Things, autonomous parking, automatic driving and the like. The on-board data processing method includes: comparing collected user behavior data with on-board data, to obtain difference data used to characterize scene data that is related to user behavior and not included in the on-board data; reporting the difference data; and updating the on-board data by using a downloaded data package obtained through the difference data, in response to a data update operation. By adopting the method, the accuracy of driving in the automatic driving scene may be improved.

Abstract: A polishing composition includes an abrasive; a pH adjuster; a barrier film removal rate enhancer; a low-k removal rate inhibitor; an azole-containing corrosion inhibitor; and a hard mask removal rate enhancer. A method of polishing a substrate includes the steps of: applying the polishing composition described herein to a surface of a substrate, wherein the surface comprises ruthenium or a hard mask material; and bringing a pad into contact with the surface of the substrate and moving the pad in relation to the substrate.

Abstract: A method for enabling secure communication. The method includes providing a first virtual network function (“VNF”) at a first network location and providing a second VNF at a second network location. A first Layer 3 virtual private network (“L3 VPN”) tunnel is constructed by the first VNF and the second VNF between the first network location and the second network location, and a first local area network (“LAN”) at the first network location and a second LAN at the second network location are connected by the first L3 VPN tunnel. Further provided is a method for establishing a secure communication environment.

Abstract: This application discloses signal processing methods and apparatuses, in the field of radar technologies, and may be applied to scenarios such as intelligent transportation (for example, intelligent transportation, assisted driving, or autonomous driving), a smart home, and a robot. In an example method, a first range time-domain signal of a first subband and a second range time-domain signal of a second subband adjacent to the first subband are obtained. The first range time-domain signal and the second range time-domain signal are synthesized and superposed to obtain a third range time-domain signal. A first peak point and a second peak point of the third range time-domain signal are obtained. A constant phase error ?err between the first range time-domain signal and the second range time-domain signal is obtained based on the first peak point and the second peak point.

Abstract: The present disclosure provides a method and apparatus for processing three dimensional graphic data, a device, a storage medium and a product, relating to a field of artificial intelligence, in particular to a field of autonomous driving. The specific implementation is: receiving a data compression request for a target graphic element in a three dimensional electronic map, and obtaining at least one vertex data corresponding to the target graphic element; extracting a global coordinate matrix with a shared attribute in the at least one vertex data; extracting local coordinate data with a private attribute respectively corresponding to the at least one vertex data; and sending, in response to a graphic drawing request for the target graphic element, the global coordinate matrix and the local coordinate data respectively corresponding to the at least one vertex data to a graphic display device.

Abstract: This disclosure relates to a method that includes applying a polishing composition to a surface of a substrate; bringing a pad into contact with the surface of the substrate and moving the pad in relation to the substrate to create a polished substrate; treating the polished substrate with a rinse solvent; flowing a vapor over a meniscus formed at an interface between air and the rinse solvent on the polished substrate. The vapor includes a first component containing a water miscible organic solvent, a second component containing a cleaning agent, and a third component containing an inert gas.

Abstract: Provided are a method for processing an image, an electronic device, a vehicle, a server, and a storage medium, which relate to a field of artificial intelligence technology, and in particular, to the fields of autonomous driving, intelligent transportation, and the like. The specific implementation scheme is as follows: sending at least one piece of image information to a server, the at least one piece of image information being collected by a vehicle during driving in a target area; acquiring a first mapping result generated by the server, the first mapping result including first environmental characteristic information in the target area; and storing the first mapping result as the map information of the target area, the map information of the target area being used for driving the autonomous driving of the vehicle in the target area.

Abstract: Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.

Abstract: A distributed microwave radar imaging method includes obtaining a first echo signal received by a first microwave radar, where the first microwave radar is disposed at a first height; obtaining a second echo signal received by a second microwave radar, where the second microwave radar is disposed at a second height, and the first height is lower than the second height; determining a first radar imaging result image of a detected target based on the first echo signal; determining a second radar imaging result image of the detected target based on the second echo signal; fusing the first radar imaging result image and the second radar imaging result image to obtain a target fused image; and determining outline information of the detected target based on the target fused image.

Abstract: Disclosed are an optically pure oxaspiro-substituted pyrrolopyrazole derivative, a preparation method therefor and the pharmaceutical use thereof. The compounds are compounds as shown in formula (I) and formula (II) or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof.

Abstract: Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.

Abstract: An electronic device for optically detecting an appearance of a product for defects includes a first camera device, a second camera device, at least one white light source, and at least one red light source. The first camera device is perpendicular to a plane of the product to be detected. When the red light source is activated, the first camera device captures images of edges of the plane of the product, when the white light source is activated, the second camera device captures images of the plane of the product. The electronic device detects the appearance of the plane of the product for defects according to the images captured by the first and second camera devices, the defects can include stair slope errors, scratches, sanding marks, and gas marks.

Abstract: The disclosure provides a method for determining a slope slip plane with a gently-inclined soft interlayer, including: S1, determining a curve formed with a slip arc of a trailing edge tearing plane, a soft interlayer plane and a slip arc of a leading edge shear opening as a slope slip plane; S2, calculating a slip plane stability coefficient; S3, determination of a position of the gently-inclined soft interlayer plane: if the slip plane stability coefficient is less than 1 but close to 1, determining that the position of the slope slip plane is accurate; otherwise, moving the position of the soft interlayer plane and repeating steps S1 and S2, until the slip plane stability coefficient is less than 1 and close to 1. The method is simple, and has a high accuracy for determining a non-circular slip plane with a soft interlayer as a bottom slip plane.

Abstract: An amorphous solid form of a compound comprising of the angiotensin receptor antagonist (ARB) valsartan, the neutral endopeptidase inhibitor (NEPi) (2R,4S)-5-biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methylpentanoic acid ethyl ester and sodium cations is provided. This is compound is useful for the treatment of hypertension and/or heart failure.

Abstract: An example circuit includes a substrate having a surface and electrically conductive lines. The electrically conductive lines extend in a direction substantially parallel to the surface and substantially orthogonal to a virtual centerline. The circuit also includes first and second instances of a driver device having respective first and second sides, and respective line outputs. The line outputs are arranged along the first side of the respective instance of the driver device, and the respective first side of each of the first and second instances of the driver device are nearer the virtual centerline than the second side thereof. The line outputs of the first instance of the driver device are coupled to a first set of the electrically conductive lines, and the line outputs of the second instance of the driver device are coupled to a second set of the electrically conductive lines.

Abstract: A polishing composition includes an anionic abrasive, a pH adjuster a low-k removal rate inhibitor, a ruthenium removal rate enhancer, and water. A method of polishing a substrate includes the steps of: applying the polishing composition described herein to a surface of a substrate, wherein the surface comprises ruthenium or a hard mask material; and bringing a pad into contact with the surface of the substrate and moving the pad in relation to the substrate.