Abstract: The invention provides a compound of formula (I), a pharmaceutical composition thereof, a method of preparing a medicament for the treatment of a cancer, and a method of treating cancers. The invention exhibits merits against cancers such as significantly higher potency and effectiveness over a broader range of cancers. In formula (I), Ra is a benzyl group with alkyl and/or alkoxy; Rb is selected from H and alkyl groups; Rf is an alkyl; and R3 is selected from a substituted phenyl, a heterocyclic group, and wherein Rc is selected from a fused ring, fused rings, and any bivalent cyclic group.

Abstract: A method for identifying the type of faults occurred on a power line, characterized in that it comprises: calculating a fault point voltage on fault points based on terminal voltage and fault locations of the power line; adopting the fault point voltage corresponding to a maximum transition resistance as a setting value; comparing the fault point voltage on fault points with the setting value; and identifying the type of fault as a permanent type or a transient type based on the result of the comparison.

Abstract: The present invention provides a new synchronization method named Multi-Node Echo Method (MNEM), which settles the problem of clock/data synchronization with asymmetrical channels. In MNEM, the echo messages are relayed among multi-node loop both by clockwise and anti-clockwise. Based on Multi-Node Echo Method, the invention further provides a method to detect symmetrical status of a communication network, a method to detect asymmetrical status of any channel in a communication network, and a method to calculate the sending and receiving delay values of any channel in a communication network, even when the channel is asymmetrical.

Abstract: An exemplary pin bending device (200) includes a base (210), a sliding member (230), a fixing member (240), and a latch member (250). The sliding member (230) is slidably positioned on the base and defines a plurality of holes (2303) for receiving first portions of pins. The fixing member is fixed on the base. The latch member is movably positioned on the base. The latch member is able to move towards the fixing member in a direction perpendicular to the sliding direction of the sliding member and engage with the fixing member to fix second portions of the pins.

Abstract: A method and a protection IED for supervising a secondary circuit of an instrument transformer in a power system are disclosed. The instrument transformer is connected to a power system component. The method includes: detecting, by a protection IED which is connected to the secondary circuit of the instrument transformer and protects the power system component, disturbances in a signal from the instrument transformer; and determining whether a failure occurs in the secondary circuit of the instrument transformer, according to both a disturbance detection result from the protection IED and another disturbance detection result from at least one of other protection IEDs.

Abstract: The present invention discloses a fast power swing unblocking method and apparatus for a distance protection in a power system, which is able to ensure fast phase-segregated tripping of distance protection for faults during a power swing (3-phase or 2-phase swing). The power swing unblocking method in a power system according to the present invention comprises calculating changing rates of impedances for all operating loops of the distance protection in the power system; and determining a fault loop based on the calculated changing rates. If there is a fault loop, a blocked distance zone for the fault loop is unblocked. Before calculating the changing rates, whether the power system is under a power swing is checked and a distance zone that might mal-operate under the power swing is blocked if it is checked that the power system is under the power swing.

Abstract: A method and a system for rearranging sound conductors included in parallel lines in power transmission are provided. The parallel lines include at least a first line (L1) and a second line (L2) each of which includes N conductors (1A, 1B, and 1C; or, 2A, 2B, and 2C), N is an integer number greater than or equal to 3. The method includes: selecting any N sound conductors (1B, 1C, 2C) which are not included in one line, among the 2N conductors (1A, 1B, and 1C; 2A, 2B, and 2C) included in the two lines (L1, L2); connecting each of one or more unselected conductors (1A) included in the first line (L1) to a corresponding one of one or more selected sound conductors (2C) included in the second line (L2) while keeping the second line (L2) tripped, so that a reconstructed line is formed by using the N selected sound conductors (1B, 1C, 2C) to resume power transmission of the first line (L1).

Abstract: A method and apparatus for fault identification in a transmission line are provided. The method may include measuring at an end of the transmission line when the transmission line has a fault to obtain a measured signal g(t), comparing the measured signal g(t) with a predefined standard signal f(t), the predefined standard signal f(t) having beat frequency characteristic; and identifying that the fault is a transient fault if the measured signal g(t) matches the predefined standard signal f(t) according to a result of the comparison, or the fault is a permanent fault if the measured signal g(t) does not match the predefined standard signal f(t) according to the result of the comparison.

Abstract: A Voice over Internet Protocol (VoIP) system includes two or more VoIP terminals, a monitoring server (30), and a soft switch device (10). The soft switch is capable of determining whether or not phone number associated with at least one of the two or more VoIP terminals is predetermined to be monitored, amending information associated with communication between the two or more VoIP terminals, and establishing the communication between the two or more VoIP terminals through the monitoring server. The monitoring server is capable of reading voice data packets sent between the two or more VoIP terminals.

Abstract: A pressure-induced counter includes a pressure acquisition unit, a delay unit and a counter unit. The pressure acquisition unit is electrically coupled to the counter unit via the delay unit. The pressure acquisition unit is configured for acquiring a pressure signal of an external pressure applied thereon to generate and output an original electrical signal corresponding to the pressure signal. The delay unit is configured for processing the original electrical signal outputted from the pressure acquisition unit to obtain a processed electrical signal by depressing the leading-edge jitter existing therein. The counter unit is configured for receiving the processed electrical signal transmitted from the delay unit and taking count of the received signals.

Abstract: Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloalkyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alkyl, aryl, alkylaryl, arylalkyl, and cycloalkyl; R3, with the base nitrogen, forms an amide or sulfonamide; R4 is selected from nitro, amine, amide, and benzamide; or a pharmaceutically acceptable salts thereof. Also provided are small molecule selective aromatase inhibitors having a molecular weight of less 500 g/mol. In some embodiments, the small molecule selective aromatase inhibitors described herein have a molecular weight of less than 450 g/mol. Also provided are methods for suppressing aromatase activity expression in cancer cells comprising the step of administering a pharmaceutically effective amount of a small molecule aromatase inhibitor to a subject in need of such treatment. In one embodiment, the cancer cells are breast cancer cells.

Abstract: A method for media communication through NAT includes assigning a relay port and sending a command to a media relay server by a soft switch device, amending signaling messages of a caller IP terminal and a callee IP terminal so that media packets of the caller IP terminal and the callee IP terminal are transmitted to the media relay server using the soft switch device, and receiving the media packets on the relay port, recording IP addresses, and establishing corresponding connection of the caller IP terminal and the callee IP terminal for relaying the following media packets as the media relay server.

Abstract: A Voice over Internet Protocol (VoIP) system includes two or more VoIP terminals, a monitoring server (30), and a soft switch device (10). The soft switch is capable of determining whether or not phone number associated with at least one of the two or more VoIP terminals is predetermined to be monitored, amending information associated with communication between the two or more VoIP terminals, and establishing the communication between the two or more VoIP terminals through the monitoring server. The monitoring server is capable of reading voice data packets sent between the two or more VoIP terminals.

Abstract: An exemplary pin bending device (200) includes a base (210), a sliding member (230), a fixing member (240), and a latch member (250). The sliding member (230) is slidably positioned on the base and defines a plurality of holes (2303) for receiving first portions of pins. The fixing member is fixed on the base. The latch member is movably positioned on the base. The latch member is able to move towards the fixing member in a direction perpendicular to the sliding direction of the sliding member and engage with the fixing member to fix second portions of the pins.

Abstract: A pressure-induced counter includes a pressure acquisition unit, a delay unit and a counter unit. The pressure acquisition unit is electrically coupled to the counter unit via the delay unit. The pressure acquisition unit is configured for acquiring a pressure signal of an external pressure applied thereon to generate and output an original electrical signal corresponding to the pressure signal. The delay unit is configured for processing the original electrical signal outputted from the pressure acquisition unit to obtain a processed electrical signal by depressing the leading-edge jitter existing therein. The counter unit is configured for receiving the processed electrical signal transmitted from the delay unit and taking count of the received signals.

Abstract: Aromatase inhibitors (AIs) are disclosed which are useful in the treatment and prevention of post-menopausal breast cancer. New AIs derived from natural products are disclosed that are evaluated for clinical utility for treating post-menopausal breast cancer and may also act as chemopreventive agents for preventing breast cancer. Several pure compounds demonstrated AI activity using a noncellular, enzyme-based microsomal and a cell-based aromatase assay. Correlations are made between structural classes with levels of aromatase inhibition. The disclosure may be utilized to direct synthetic modification of natural product scaffolds to enhance aromatase inhibition or to standardize botanical dietary supplements for increased aromatase inhibition activity.

Abstract: A system includes a mounting device (200), a detecting device (100), and a circuit (300). The mounting device includes a base (210), and a mounting head (220) opposite to the base. The detecting device is fixed on the base, and includes a shell (110) comprising a cavity (112) therein, a probe (130) fixed in the cavity and protruding towards the through hole, and a plug (150) having a pin (152) made of conductive materials. The shell further includes an opening (118) communicating with the cavity, and a through hole (114) formed opposite to the mounting head and communicating with the cavity. The pin is connected to the probe through the opening. The circuit includes a PLC circuit (320), and a power supply (310) connected with the PLC circuit. The pin connects with one of the PLC circuit and power circuit, and the mounting head connects with the remaining one.

Abstract: A surface treatment apparatus (100) comprises a transporting device (20), a planishing device (30) and a driving device (10). The transporting device comprises a base (21). The base comprises a front portion (212), a rear portion (214), and a pair of parallel middle portions (216) each comprising a slideway, which defines an opening therein. The base still comprising a sliding block (26) received in the opening (218), with two sides of the sliding block respectively slidably received in the slideways in the pair of middle portions. The planishing device comprises a pair of mounting blocks (32) fixed on the sliding block, at least one axle (34) fixed between the mounting blocks, and at least one wheels (342) fixed on the axle. The driving device is used for driving the sliding block to slide in the opening.