Abstract: A pressure-induced counter includes a pressure acquisition unit, a delay unit and a counter unit. The pressure acquisition unit is electrically coupled to the counter unit via the delay unit. The pressure acquisition unit is configured for acquiring a pressure signal of an external pressure applied thereon to generate and output an original electrical signal corresponding to the pressure signal. The delay unit is configured for processing the original electrical signal outputted from the pressure acquisition unit to obtain a processed electrical signal by depressing the leading-edge jitter existing therein. The counter unit is configured for receiving the processed electrical signal transmitted from the delay unit and taking count of the received signals.

Abstract: Aromatase inhibitors (AIs) are disclosed which are useful in the treatment and prevention of post-menopausal breast cancer. New AIs derived from natural products are disclosed that are evaluated for clinical utility for treating post-menopausal breast cancer and may also act as chemopreventive agents for preventing breast cancer. Several pure compounds demonstrated AI activity using a noncellular, enzyme-based microsomal and a cell-based aromatase assay. Correlations are made between structural classes with levels of aromatase inhibition. The disclosure may be utilized to direct synthetic modification of natural product scaffolds to enhance aromatase inhibition or to standardize botanical dietary supplements for increased aromatase inhibition activity.

Abstract: A system includes a mounting device (200), a detecting device (100), and a circuit (300). The mounting device includes a base (210), and a mounting head (220) opposite to the base. The detecting device is fixed on the base, and includes a shell (110) comprising a cavity (112) therein, a probe (130) fixed in the cavity and protruding towards the through hole, and a plug (150) having a pin (152) made of conductive materials. The shell further includes an opening (118) communicating with the cavity, and a through hole (114) formed opposite to the mounting head and communicating with the cavity. The pin is connected to the probe through the opening. The circuit includes a PLC circuit (320), and a power supply (310) connected with the PLC circuit. The pin connects with one of the PLC circuit and power circuit, and the mounting head connects with the remaining one.

Abstract: A surface treatment apparatus (100) comprises a transporting device (20), a planishing device (30) and a driving device (10). The transporting device comprises a base (21). The base comprises a front portion (212), a rear portion (214), and a pair of parallel middle portions (216) each comprising a slideway, which defines an opening therein. The base still comprising a sliding block (26) received in the opening (218), with two sides of the sliding block respectively slidably received in the slideways in the pair of middle portions. The planishing device comprises a pair of mounting blocks (32) fixed on the sliding block, at least one axle (34) fixed between the mounting blocks, and at least one wheels (342) fixed on the axle. The driving device is used for driving the sliding block to slide in the opening.

Abstract: A clamp changing apparatus includes a holder (70) including a plurality of clamp-holding devices (72), each of which holding a clamp (10) thereon, a robot (50) including a shaft (501), and a coupling device (30) secured on the shaft of the robot. The robot selects one of the clamps held on the clamp-holding devices according to a predetermined machining program therein, changes out a used clamp for the selected clamp, and mounts the selected clamp on the coupling device.

Abstract: A system includes a mounting device (200), a detecting device (100), and a circuit (300). The mounting device includes a base (210), and a mounting head (220) opposite to the base. The detecting device is fixed on the base, and includes a shell (110) comprising a cavity (112) therein, a probe (130) fixed in the cavity and protruding towards the through hole, and a plug (150) having a pin (152) made of conductive materials. The shell further includes an opening (118) communicating with the cavity, and a through hole (114) formed opposite to the mounting head and communicating with the cavity. The pin is connected to the probe through the opening. The circuit includes a PLC circuit (320), and a power supply (310) connected with the PLC circuit. The pin connects with one of the PLC circuit and power circuit, and the mounting head connects with the remaining one.

Abstract: Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloalkyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alkyl, aryl, alkylaryl, arylalkyl, and cycloalkyl; R3, with the base nitrogen, forms an amide or sulfonamide; R4 is selected from nitro, amine, amide, and benzamide; or a pharmaceutically acceptable salts thereof Also provided are small molecule selective aromatase inhibitors having a molecular weight of less 500 g/mol. In some embodiments, the small molecule selective aromatase inhibitors described herein have a molecular weight of less than 450 g/mol. Also provided are methods for suppressing aromatase activity expression in cancer cells comprising the step of administering a pharmaceutically effective amount of a small molecule aromatase inhibitor to a subject in need of such treatment. In one embodiment, the cancer cells are breast cancer cells.

Abstract: A surface treatment apparatus (100) comprises a transporting device (20), a planishing device (30) and a driving device (10). The transporting device comprises a base (21). The base comprises a front portion (212), a rear portion (214), and a pair of parallel middle portions (216) each comprising a slideway, which defines an opening therein. The base still comprising a sliding block (26) received in the opening (218), with two sides of the sliding block respectively slidably received in the slideways in the pair of middle portions. The planishing device comprises a pair of mounting blocks (32) fixed on the sliding block, at least one axle (34) fixed between the mounting blocks, and at least one wheels (342) fixed on the axle. The driving device is used for driving the sliding block to slide in the opening.

Abstract: A clamp changing apparatus includes a holder (70) including a plurality of clamp-holding devices (72), each of which holding a clamp (10) thereon, a robot (50) including a shaft (501), and a coupling device (30) secured on the shaft of the robot. The robot selects one of the clamps held on the clamp-holding devices according to a predetermined machining program therein, changes out a used clamp for the selected clamp, and mounts the selected clamp on the coupling device.

Abstract: A method is directed to coating a light source. The method provides a setup stage, a coating stage and an optional drying stage. The setup stage involves a loading of a luminescent spray solution into a reservoir of an inkjet printer cartridge, a setting of a spraying distance between a platform and the inkjet printer cartridge, and a creation of a spray profile drawing corresponding to the light source. The coating stage involves a secure positioning of the light source on the platform, and a printing of the spray profile drawing where the luminescent material is sprayed upon the diode(s) of the light source. The final drying stage implements a crosslinking technique or curing technique to dry the coated diode(s).