Abstract: Provided are a connection establishment method and device, a storage medium and an electronic device. In the connection establishment method, a target module acquires a connection request, wherein the connection request is used for requesting establishment of a connection between a terminal application and a target service, and the connection request contains a target service identifier of the target service; and the target module initiates the connection request to the target service based on the target service identifier to request the establishment of the connection between the terminal application and the target service.

Abstract: Provided are a method for receiving border gateway protocol (BGP)-intent route, and a method for advertising BGP-intent route. The method for receiving BGP-intent route includes: receiving the BGP-intent route advertised by a BGP speaker, where the BGP-intent route carries at least one of the following: a metric type, a metric and metric credit information.

Abstract: present disclosure relates, in part, to SARS-CoV-2 papain-like protease (PLpro) inhibitors of Formula (I), pharmaceutical compositions thereof, and methods of using the same for promoting an antiviral effect in a subject and/or treating, preventing, and/or ameliorating a viral infection in a subject:

Abstract: A method for packet scheduling, a network device, a storage medium, and a computer program product are disclosed. The method may include acquiring a local deadline time indicative of a maximum allowable residence time of a packet at a local node; acquiring a cumulative deadline time indicative of a sum of each local deadline time that the packet goes through at each upstream node via which the packet is transferred, and a cumulative residence time indicative of the sum of each local residence time that the packet goes through at each upstream node via which the packet is transferred; and calculating a deadline time adjustment value according to the local deadline time, the cumulative deadline time, and the cumulative residence time; and adjusting a time at which the packet is sent according to the deadline time adjustment value.

Abstract: The present disclosure relates, in part, to SARS-CoV-2 papain-like protease (PLpro) inhibitor compounds of Formula (I), pharmaceutical compositions thereof, and methods of using the same for promoting an antiviral effect in a subject and/or treating, preventing, and/or ameliorating a viral infection in a subject:

Abstract: Provided are resource deployment and application data routing methods and apparatuses, and a storage medium. The application data routing method includes: receiving application data sent by an application client, wherein the application data carries or indicates a first cloud resource node list, and the first cloud resource node list comprises one or more cloud resource nodes; determining a target cloud resource node from the first cloud resource node list according to a cloud resource state of each of the one or more cloud resource nodes and a network state between the application client and each of the one or more cloud resource nodes; and routing and forwarding the application data to the target cloud resource node.

Abstract: Disclosed are a data transmission system, method, and apparatus, a device, and a medium, used for solving the problem in the prior art of low data transmission efficiency in a remote vehicle diagnostic process. Specifically, a vehicle diagnostic device establishes a UDT communication connection with a remote diagnostic server, and during a data transmission process, the vehicle diagnostic device periodically determines a current congestion value on the basis of a transmission delay between the vehicle diagnostic device and the remote diagnostic server, a network state of the vehicle diagnostic device, and the load capacity of the remote diagnostic server, and according to a target transmission rate corresponding to the current congestion value, sends a UDT data packet encapsulated by data to be transmitted of a target vehicle.

Abstract: Disclosed is an intelligent recognition method for a time sequence image of a concrete dam defect. The method includes: extracting a feature sequence of the time sequence image containing the concrete dam defect; matching a located defect with a real defect by using an objective function; adding a loss term based on a tight sensing intersection-over-union to a loss function of a model so as to pay attention to integrity of a defect sequence and improve accuracy; and extracting a defect feature and recognizing a defect type after completing defect location. According to the present disclosure, the time sequence image of the concrete dam defect is detected effectively, so that a defect in a long image sequence can be located and the defect type can be recognized accurately.

Abstract: A PI3K inhibitor, a preparation method therefor, and a use thereof are provided. The PI3K inhibitor of is a compound of formula I, or a salt thereof, a stereoisomer thereof, a solvate thereof, a hydrate thereof, or a prodrug thereof. The prepared compound can be used for preparing a PI3K selective inhibitor and for preparing a drug for preventing and/or treating a disease related to PI3K, such as a drug for preventing and/or treating cancer.

Abstract: A path calculation method, which is applied to a head node, may include: acquiring virtual networks and Cyclic Queuing and Forwarding (CQF) scheduling parameters supported by nodes, where each of the nodes supports at least one CQF scheduling parameter; acquiring a target binding relationship, where the target binding relationship is a binding relationship between a target virtual network and a target CQF scheduling parameter; determining a plurality of target nodes and a plurality of target links belonging to the target virtual network according to the target binding relationship and the virtual networks and the CQF scheduling parameters supported by the nodes; and calculating a target path to a tail node in the target virtual network according to the plurality of target nodes, the plurality of target links, and the target CQF scheduling parameter.

Abstract: This application provides a composite separator and a battery. In a first aspect, this application provides a composite separator, which includes a base film and an adhesive coating. The adhesive coating includes polyethylene wax particles and inorganic particles. The polyethylene wax particles can play a good adhesive role, prevent dimensional changes caused by release of internal stress, and improve the problem of wrinkling of the separator upon electrolyte injection. The inorganic particles play a supporting role. By adjusting the weight ratio and the size ratio of the polyethylene wax particles and the inorganic particles, and the weight of the polyethylene wax particles per unit area, the air permeability increase before and after providing the adhesive coating and the air permeability increase of the composite separator before and after hot pressing can be reduced on the basis of ensuring the adhesion force of the composite separator.

Abstract: The invention provides a compound of formula (I): or a salt thereof, R1-R4, X, L, and ring A have any of the values described in the specification, as well as compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof. The compounds are useful as inhibitors of papain-like protease and as antiviral agents.

Abstract: The present application proposes a method and system for quantitative derivation of an on-line evaluation layered model for evaluating concrete dam operation performance, and a storage medium, and relates to the technical field of dam operation safety monitoring and management. A logic architecture of quantitative derivation of the concrete dam operation performance mainly has two aspects, a longitudinal dimension and a transverse dimension. The longitudinal dimension is the principal line of assessing longitudinal evaluation of the on-line evaluation layered model, and an analysis idea of the concrete dam from local to global and from details to whole is objectively reflected from six levels of monitoring data, diagnosis methods, monitored items, evaluation indicators, key parts and an overall project.

Abstract: Provided are a CD80 protein variant and a fusion protein comprising the CD80 protein variant, which can bind to PD-L1, CTLA-4 and CD28, activate the activity of T lymphocytes, and inhibit the growth and/or proliferation of tumors or tumor cells. Also provided are a nucleic acid encoding the fusion protein, a vector comprising the fusion protein, a cell comprising the nucleic acid or the vector, a method for preparing the fusion protein, and use of the fusion protein.

Abstract: A display substrate and a manufacturing method therefor, and a display apparatus. The display substrate includes a plurality of first electrodes (31) and a plurality of pixel definition structures (32) disposed on the base substrate (10). The pixel definition structures (32) are disposed between adjacent first electrodes (31) and forming pixel openings (35) exposing the first electrodes (31). A pixel definition structure (32) includes at least a first insulating layer (101), a second insulating layer (102), a third insulating layer (103), and a fourth insulating layer (104). An orthographic projection of the second insulating layer (102) on the base substrate at least partially overlaps an orthographic projection of a first electrode (31) on the base substrate. A surface of the second insulating layer (102) is provided with a second recess (106).

Abstract: Provided in the embodiments of the present disclosure are a routing method and apparatus, a cloud resource registering method and apparatus, and a storage medium and an electronic apparatus.

Abstract: Disclosed are a battery, and a battery diaphragm and a manufacturing method therefor, which belong to the field of batteries. The battery diaphragm has a composite structure constituted by a first member and a second member. The diaphragm comprises: the first element is manufactured from a modification material provided to improve the thermal stability of the diaphragm, the first element being a stack of nanowires distributed in layers; and the second element is manufactured from a base material provided to serve as the body of the diaphragm, the first element being loaded on the second element and supported by the second element. The battery diaphragm has a good thermal stability.

Abstract: A method for packet scheduling, a network device, a storage medium, and a computer program product are disclosed. The method may include acquiring a local deadline time indicative of a maximum allowable residence time of a packet at a local node; acquiring a cumulative deadline time indicative of a sum of each local deadline time that the packet goes through at each upstream node via which the packet is transferred, and a cumulative residence time indicative of the sum of each local residence time that the packet goes through at each upstream node via which the packet is transferred; and calculating a deadline time adjustment value according to the local deadline time, the cumulative deadline time, and the cumulative residence time; and adjusting a time at which the packet is sent according to the deadline time adjustment value.

Abstract: A path calculation method, which is applied to a head node, may include: acquiring virtual networks and Cyclic Queuing and Forwarding (CQF) scheduling parameters supported by nodes, where each of the nodes supports at least one CQF scheduling parameter; acquiring a target binding relationship, where the target binding relationship is a binding relationship between a target virtual network and a target CQF scheduling parameter; determining a plurality of target nodes and a plurality of target links belonging to the target virtual network according to the target binding relationship and the virtual networks and the CQF scheduling parameters supported by the nodes; and calculating a target path to a tail node in the target virtual network according to the plurality of target nodes, the plurality of target links, and the target CQF scheduling parameter.

Abstract: Provided is a SIRP? variant and a fusion protein thereof, capable of specifically blocking interaction between CD47 protein and SIRP?, not causing coagulation reaction, and capable of inhibiting growth and/or proliferation of tumors or tumor cells.