Patents by Inventor Bin Ye

Bin Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110045508
    Abstract: The present invention is directed to diagnostic methods based upon the detection of peptides derived from the degradation of CA125. In particular, it is concerned with assays of urine samples collected from women for the purpose of determining whether they are at increased risk for having ovarian cancer, have decreased their risk as the result of clinical or non-clinical procedures, to monitor the efficacy of a treatment method, or to determine whether cancer has recurred or advanced.
    Type: Application
    Filed: January 30, 2009
    Publication date: February 24, 2011
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Bin Ye, Daniel Cramer
  • Patent number: 7828481
    Abstract: A medical table wherein a top board on which a patient is placed is supported by a base having an internal instrument so as to be movable parallel to the board surface, the medical table includes a detecting device that detects the possibility that a hand or fingers, which grip the top board, come in contact with the internal instrument during the movement of the top board or internal instrument, and a preventing device that prevents the movement of the top board or the internal instrument on the basis of a detection signal of the detecting device.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: November 9, 2010
    Assignee: GE Medical Systems Global Technology Company, LLC
    Inventors: Bin Ye, Jiake Xu, Shaobo Gu, Feng Wang
  • Publication number: 20100275219
    Abstract: A network storage monitor system includes a device driver running on each of at least one first computer and a monitor application running on a second computer in communication with the each first computer. Each first computer also is in communication with a network storage switch and the network storage switch is in communication with at least one storage device. Each device driver sends to the second computer data regarding a storage event when the storage event is initiated by the respective first computer.
    Type: Application
    Filed: April 23, 2009
    Publication date: October 28, 2010
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: William G. Carlson, Ian MacQuarrie, Eric Wieder, Bin Ye
  • Patent number: 7794145
    Abstract: A medical table in which a top plate for a patient to lie on is supported by a pedestal base in a manner to be able to move parallel to a plate surface, includes a detecting device for detecting that fingers holding the top plate are about to collide against the pedestal base when moving the top plate, and a stopping device for stopping movement of the top plate according to a detection signal from the detecting device.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: September 14, 2010
    Assignee: GE Medical Systems Global Technology Company, LLC
    Inventors: Jiake Xu, Bin Ye
  • Publication number: 20100210630
    Abstract: This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
    Type: Application
    Filed: April 30, 2010
    Publication date: August 19, 2010
    Inventors: Damian Arnaiz, Greg Brown, Emmanuel Claret, Arwed Cleve, David Davey, William Guilford, Seock-Kyu Khim, Thomas Kirkland, Monica J. Kochanny, Amy Liang, David Light, John Parkinson, David Vogel, Guo Ping Wei, Bin Ye
  • Patent number: 7737145
    Abstract: This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: June 15, 2010
    Assignee: Estrellita Pharmaceuticals, LLC
    Inventors: Damian Arnaiz, Greg Brown, Emmanuel Claret, Arwed Cleve, David Davey, William Guilford, Seock-Kyu Khim, Thomas Kirkland, Monica J. Kochanny, Amy Liang, David Light, John Parkinson, David Vogel, Guo Ping Wei, Bin Ye
  • Patent number: 7549799
    Abstract: A radiographic system (100) is provided wherein a single X-ray detector can be handled freely using a cable and which can prevent an operator or a patient from being troubled by the cable. The radiographic system (100) comprises a radiographic panel (5) configured to radiograph in two dimensions a radiation exposed to a subject and output radiation image data, a cable (6) for the supply of electric power to the radiographic panel and transfer of the radiation image data, a conveyance unit (8) for conveying the cable in a predetermined direction, a cable length adjusting unit (7) provided in the conveyance unit to adjust the length of the cable, and a movement control unit (72) configured to move the conveyance unit in accordance with a tilting direction of the cable from the cable length adjusting unit to the radiographic panel.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: June 23, 2009
    Assignee: GE Medical Systems Global Technology Company, LLC
    Inventor: Bin Ye
  • Publication number: 20090099102
    Abstract: The present invention is directed to pharmaceutical compositions and nutritional supplements that contain large amount of ginkgolides, particularly ginkgolide A or B, and for which, the other components normally found in Ginkgo biloba extracts have been removed. The compositions may be administered to women to prevent or treat ovarian cancer, particularly non-mucinous ovarian cancer.
    Type: Application
    Filed: October 24, 2006
    Publication date: April 16, 2009
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Bin Ye, Daniel Cramer
  • Publication number: 20090086930
    Abstract: A medical table in which a top plate for a patient to lie on is supported by a pedestal base in a manner to be able to move parallel to a plate surface, includes a detecting device for detecting that fingers holding the top plate are about to collide against the pedestal base when moving the top plate, and a stopping device for stopping movement of the top plate according to a detection signal from the detecting device.
    Type: Application
    Filed: September 25, 2008
    Publication date: April 2, 2009
    Inventors: Jiake Xu, Bin Ye
  • Publication number: 20090086929
    Abstract: A medical table wherein a top board on which a patient is placed is supported by a base having an internal instrument so as to be movable parallel to the board surface, the medical table includes a detecting device that detects the possibility that a hand or fingers, which grip the top board, come in contact with the internal instrument during the movement of the top board or internal instrument, and a preventing device that prevents the movement of the top board or the internal instrument on the basis of a detection signal of the detecting device
    Type: Application
    Filed: September 25, 2008
    Publication date: April 2, 2009
    Inventors: Bin Ye, Jiake Xu, Shaobo Gu, Feng Wang
  • Patent number: 7485455
    Abstract: The present invention discloses four groups of SCN5A variants that represent the most common SCN5A variants in humans. A specific mutation in one of the variants has been shown to display a different phenotype in relation to a human heart disease than other variants and known human sodium channel ? subunits with corresponding mutations. The present invention provides new tools to study mutations and to design or identify new diagnostic and treatment strategies or agents for sodium channel related diseases or conditions.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: February 3, 2009
    Assignees: Wisconsin Alumni Research Foundation, Mayo Clinic Health Solutions
    Inventors: Jonathan C. Makielski, Bin Ye, Michael J. Ackerman
  • Publication number: 20080293087
    Abstract: The present invention relates to isolated sulfonylurea receptor polynucleotides and polypeptides, as well as vectors and cells lines containing the polynucleotides and polypeptides. The present invention also relates to methods of using cell lines containing the polynucleotides and polypeptides to identify agents that are useful in ischemic preconditioning.
    Type: Application
    Filed: October 31, 2007
    Publication date: November 27, 2008
    Inventors: Jonathan C. Makielski, Nian-Qing Shi, Bin Ye
  • Publication number: 20080176833
    Abstract: This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.
    Type: Application
    Filed: December 13, 2007
    Publication date: July 24, 2008
    Inventors: Marc Adler, Stefan Baeurle, Judi Bryant, Ming Chen, Yuo-Ling Chou, Paul Hrvatin, Seock-Kyu Khim, Monica Kochanny, Wheeseong Lee, Michael Mamounas, Janet Meurer Ogden, Gary Bruce Phillips, Victor Selchau, Christopher West, Bin Ye, Shendong Yuan, Martin Krueger
  • Publication number: 20080159485
    Abstract: A radiographic system(100) is provided wherein a single X-ray detector can be handled freely using a cable and which can prevent an operator or a patient from being troubled by the cable. The radiographic system(100) comprises a radiographic panel(5) configured to radiograph in two dimensions a radiation exposed to a subject and output radiation image data, a cable(6) for the supply of electric power to the radiographic panel and transfer of the radiation image data, a conveyance unit(8) for conveying the cable in a predetermined direction, a cable length adjusting unit(7) provided in the conveyance unit to adjust the length of the cable, and a movement control unit(72) configured to move the conveyance unit in accordance with a tilting direction of the cable from the cable length adjusting unit to the radiographic panel.
    Type: Application
    Filed: December 28, 2007
    Publication date: July 3, 2008
    Inventor: Bin Ye
  • Patent number: 7288383
    Abstract: The present invention is directed to methods of identifying women at increased risk of having ovarian cancer. Identification is based upon the extent to which biological samples derived from the women exhibit elevated levels of eosinophil-derived neurotoxin (EDN).
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: October 30, 2007
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Bin Ye, Daniel W. Cramer, Samuel C. Mok
  • Publication number: 20070155727
    Abstract: This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4a, R4b, R4c, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, R9 and R10 are described herein, or pharmaceutically acceptable salts, solvates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and which are therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of using and preparing the compounds of the invention are also disclosed.
    Type: Application
    Filed: December 22, 2006
    Publication date: July 5, 2007
    Applicant: Schering Aktiengessellschaft
    Inventors: Ming Chen, Emmanuel Claret, Arwed Cleve, David Davey, William Guilford, Seock-Kyu Khim, Thomas Kirkland, Monica Kochanny, Amy Liang, David Light, John Parkinson, David Vogel, Guo Wei, Bin Ye, Hong Ye
  • Publication number: 20070155726
    Abstract: This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
    Type: Application
    Filed: December 22, 2006
    Publication date: July 5, 2007
    Applicant: Schering Aktiengesellschaft
    Inventors: Damian Arnaiz, Greg Brown, Emmanuel Claret, Arwed Cleve, David Davey, William Guilford, Seock-Kyu Khim, Thomas Kirkland, Monica Kochanny, Amy Liang, David Light, John Parkinson, David Vogel, Guo Wei, Bin Ye
  • Patent number: 7220856
    Abstract: The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b): enantiomers, diastereomers, salts and solvates thereof wherein R1, R2, R3, R4, R5, and R7 are as defined herein. The invention further includes a method of CCR5-mediated disorders employing such compounds.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: May 22, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Laura Dunning, Stefan Jaroch, Monica J. Kochanny, Wheeseong Lee, Xiongdong Lian, Meina Liang, Shou-Fu Lu, James Onuffer, Gary Phillips, Guo-Ping Wei, Bin Ye
  • Publication number: 20070032438
    Abstract: Pharmaceutical compositions containing taxanes having about 5 to about 75% phospholipid, about 0.01 to about 50% of a surfactant of an HLB value greater than 10, about 0.01 to about 50% alcohol and about 0.01 to about 40% taxane(s) or a derivative thereof.
    Type: Application
    Filed: August 2, 2005
    Publication date: February 8, 2007
    Applicant: TTY BIOPHARM COMPANY LIMITED
    Inventors: Yu-Fang Hu, Yao-Kun Huang, Shian-Bin Ye
  • Patent number: 7112408
    Abstract: The present invention is directed to a method for determining whether a woman has, or is likely to develop, ovarian cancer based upon assays of the alpha subunit of haptoglobin.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: September 26, 2006
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Bin Ye, Samuel C. Mok, Daniel W. Cramer, Ross S. Berkowitz, Steven Skates