Patents by Inventor Bin Zhong

Bin Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170008906
    Abstract: The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
    Type: Application
    Filed: September 22, 2016
    Publication date: January 12, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Craig A. Coburn, Steven W. Ludmerer, Kun Liu, Hao Wu, Richard Soll, Bin Zhong, Jian Zhu
  • Patent number: 9504690
    Abstract: The present invention relates to novel Tetracyclic Xanthene Derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, Y1, Y2, Z, Ra, Rb, R1a, R1b and R2 are as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Xanthene Derivative, and methods of using the Tetracyclic Xanthene Derivatives for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: November 29, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Craig A. Coburn, Stuart B. Rosenblum, Joseph A. Kozlowski, Richard Soll, Hao Wu, Bin Hu, Bin Zhong, Dahai Wang, Changmao Shen, Fei Sun
  • Publication number: 20160257697
    Abstract: Thiophene-substituted tetracyclic compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2, R3, R4 and R5 are as defined herein. The compositions comprising at least one thiophene-substituted tetracyclic compound, and methods of using the thiophene-substituted tetracyclic compounds for treating or preventing HCV infection in a patient are also provided.
    Type: Application
    Filed: December 31, 2013
    Publication date: September 8, 2016
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Ling Tong, Wensheng Yu, Joseph A. Kozlowski, Lei Chen, Oleg Selyutin, Seong Heon Kim, Michael Dwyer, Bin Hu, Bin Zhong, Dahai Wang, Jinglai Hao, Changmao Shen, Zhixin Lei, Weijun Wang
  • Publication number: 20160208139
    Abstract: A shellac coating composition for producing a shellac coating on a substrate comprises a fatty acid component, shellac and little or no volatile carrier liquid. Because the fatty acid inhibits the polymerization of the shellac when molten, the composition can be converted into a liquid state for coating purposes by simple heating, thereby eliminating the need for the volatile carrier liquid.
    Type: Application
    Filed: November 23, 2015
    Publication date: July 21, 2016
    Inventors: Katie L. Fontaine, Margaret McWeeney, Stephen A. Santos, Bin Zhong, Paul J. Pothier
  • Patent number: 9367187
    Abstract: A touch panel having at least one non-right angle corner region on a corner of the touch panel is provided. The touch panel includes a first electrode and a second electrode. The first electrode crosses the second electrode, and the first electrode is electrically isolated from the second electrode. The first electrode includes a plurality of first stripe electrodes extending along a first direction. The second electrode includes a plurality of second stripe electrodes and at least one auxiliary electrode. The second stripe electrodes extend along a second direction. The auxiliary electrode is disposed on the non-right angle corner region. An included angle between the auxiliary electrode and the second direction is less than 90 degrees. The auxiliary electrode is electrically connected to at least one of the second stripe electrodes adjacent to the auxiliary electrode.
    Type: Grant
    Filed: October 27, 2013
    Date of Patent: June 14, 2016
    Assignee: TPK Touch Systems (Xiamen) Inc.
    Inventors: Chen-Hsin Chang, Bin Zhong, Fuding Wang, Lixian Chen, Tianyan Wang
  • Publication number: 20160159752
    Abstract: The present invention is directed to piperazine derivatives, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
    Type: Application
    Filed: July 29, 2014
    Publication date: June 9, 2016
    Applicants: Merck Sharp & Dohme Corp., MSD R&D (CHINA) CO., LTD.
    Inventors: Peter D. Williams, John A. McCauley, David Jonathan Bennett, Christopher J. Bungard, Lehua Chang, Michael P. Dwyer, M. Katharine Holloway, Kartik M. Keertikar, H. Marie Loughran, Jessie J. Manikowski, Gregori J. Morriello, Dong-Ming Shen, Edward C. Sherer, Jurgen Schultz, Sherman T. Waddell, Catherine M. Wiscount, Nicolas Zorn, Xin-Jie Chu, Satyanarayana Tummanapalli, Vijayasaradhi Sivalenka, Bin Hu, Tao Ji, Bin Zhong
  • Publication number: 20150335648
    Abstract: The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2 R3, R4 and R are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: December 31, 2013
    Publication date: November 26, 2015
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Wensheng Yu, Ling Tong, Joseph A. Kozlowski, Oleg Selyutin, Lei Chen, Jae-Hun Kim, Deyou Sha, Razia Rizvi, Bandarpalle Shankar, Bin Hu, Bin Zhong, Dahai Wang, Jinglai Hao, Wei Wei, Tao Ji, Shuai Zan
  • Publication number: 20150286315
    Abstract: A touch panel includes a driving layer and a sensing layer. The driving layer has a first top surface and a driving layer edge. The first top surface has at least one first connecting region. The driving layer edge surrounds the first connecting region and there is a first distance between the first connecting region and the driving layer edge. The sensing layer is disposed on the first top surface of the driving layer. The second top surface of sensing layer away from the driving layer has at least one second connecting region. The sensing layer edge of the sensing layer surrounds the second connecting region, and there is a second distance between the sensing layer edge and the at least one second connecting region.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 8, 2015
    Inventors: Chen-Hsin Chang, Bin Zhong, Che-I Wu, Fuding Wang, Lixian Chen, Yongbin Ke
  • Publication number: 20150246917
    Abstract: The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
    Type: Application
    Filed: May 13, 2015
    Publication date: September 3, 2015
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Craig A. Coburn, Steven W. Ludmerer, Kun Liu, Hao Wu, Richard Soll, Bin Zhong, Jian Zhu
  • Patent number: 9102125
    Abstract: The printed image on a major face of a flexible food packaging film is covered by a shellac barrier coating.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: August 11, 2015
    Assignee: Mantrose-Haeuser Co., Inc.
    Inventors: Graham C. Battersby, Stephen A. Santos, Bin Zhong, Xiangdong Gan
  • Patent number: 9090661
    Abstract: The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: July 28, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Craig A. Coburn, John A. McCauley, Steven W. Ludmerer, Kun Liu, Joseph P. Vacca, Hao Wu, Bin Hu, Richard Soll, Fei Sun, Xinghai Wang, Man Yan, Chengren Zhang, Mingwei Zheng, Bin Zhong, Jian Zhu
  • Publication number: 20140371138
    Abstract: The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
    Type: Application
    Filed: August 29, 2014
    Publication date: December 18, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Craig A. Coburn, John A. McCauley, Steven W. Ludmerer, Kun Liu, Joseph P. Vacca, Hao Wu, Bin Hu, Richard Soll, Fei Sun, Xinghai Wang, Man Yan, Chengren Zhang, Mingwei Zheng, Bin Zhong, Jian Zhu
  • Publication number: 20140327870
    Abstract: A lens structure including a quarter wave plate layer and a linear polarizing plate layer is provided. When the linear polarizing plate layer is located at an outer side of the lens away from a viewer's eye, the polarizing axis of the linear polarizing plate layer is in a vertical direction. The lens structure can be used to make dual-purpose eyeglasses with sunglasses and 3D glasses functions. Any one of the quarter wave plate layer and the linear polarizing plate layer can be disposed at the outer side away from the user's eyes by adjusting the orientation of the lens of the present invention. When the linear polarizing plate layer is located at the outer side away from the user's eyes, the optical axis of the linear polarizing plate layer is in the vertical direction. Thus, the dual-purpose eyeglasses with both sunglasses and 3D glasses functions can be achieved.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 6, 2014
    Inventors: Wingyip Kenny Chow, Bin Zhong
  • Patent number: 8871759
    Abstract: The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: October 28, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Craig A. Coburn, Steven W. Ludmerer, Kun Liu, Hao Wu, Richard Soll, Bin Zhong, Jian Zhu
  • Publication number: 20140199264
    Abstract: The present invention relates to novel Tetracyclic Xanthene Derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, Y1, Y2, Z, Ra, Rb, R1a, R1b and R2 are as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Xanthene Derivative, and methods of using the Tetracyclic Xanthene Derivatives for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: March 16, 2012
    Publication date: July 17, 2014
    Inventors: Craig A. Coburn, Stuart B. Rosenblum, Joseph A. Kozlowski, Richard Soll, Hao Wu, Bin Hu, Bin Zhong, Dahai Wang, Changmao Shen, Fei Sun
  • Patent number: 8765239
    Abstract: The printed image on a major face of a flexible food packaging film is covered by a shellac barrier coating.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: July 1, 2014
    Assignee: Mantrose-Haeuser Co., Inc.
    Inventors: Graham C. Battersby, Stephen A. Santos, Bin Zhong, Xiangdong Gan
  • Patent number: 8759549
    Abstract: This invention relates to a novel compound extracted from antrodia Cinnamomea and related compounds of formula (1), and pharmaceutical compositions comprising the compound of formula (1) and a pharmaceutically acceptable carrier or excipient. The invention further comprises the method of inhibit cancer cells by administering an effective amount of the compound of formula (1).
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: June 24, 2014
    Inventors: Ching-Kuo Lee, Pi-Yu Chen, Jir-Mehng Lo, Wen-Bin Zhong, Tien-Wang Chiu, Chieh-Chou Yu
  • Publication number: 20140131069
    Abstract: The present disclosure provides a touch-sensing electrode structure, which includes a plurality of touch-sensing electrodes. Each of the touch-sensing electrodes includes a main body and a connecting portion connected to an end of the main body; wherein the width of the connecting portion is not less than a half width of the end of the main body. The touch-sensing electrode structure also includes a plurality of signal-transmitting wires, each of which includes a head portion and a tail wire connected to the head portion. The head portions of the signal-transmitting wires is superimposed on the connecting portions and electrically connected to the connecting portions respectively. Furthermore, a method of manufacturing the above touch-sensing electrode structure is also provided.
    Type: Application
    Filed: November 7, 2013
    Publication date: May 15, 2014
    Applicant: TPK Touch Systems (Xiamen) Inc.
    Inventors: Chen-Hsin Chang, Bin Zhong, Fuding Wang, Zhenjun Fei, Lixian Chen
  • Publication number: 20140118280
    Abstract: A touch panel having at least one non-right angle corner region on a corner of the touch panel is provided. The touch panel includes a first electrode and a second electrode. The first electrode crosses the second electrode, and the first electrode is electrically isolated from the second electrode. The first electrode includes a plurality of first stripe electrodes extending along a first direction. The second electrode includes a plurality of second stripe electrodes and at least one auxiliary electrode. The second stripe electrodes extend along a second direction. The auxiliary electrode is disposed on the non-right angle corner region. An included angle between the auxiliary electrode and the second direction is less than 90 degrees. The auxiliary electrode is electrically connected to at least one of the second stripe electrodes adjacent to the auxiliary electrode.
    Type: Application
    Filed: October 27, 2013
    Publication date: May 1, 2014
    Applicant: TPK Touch Systems (Xiamen) Inc.
    Inventors: Chen-Hsin Chang, Bin Zhong, Fuding Wang, Lixian Chen, Tianyan Wang
  • Publication number: 20140120216
    Abstract: Provided herein are methods and compositions for forming a coating on the external surface of a solid chocolate or chocolate-coated product. The method comprises applying at least one layer of a coating composition comprising a solvent selected from water, ethanol, and isopropanol, or any combination thereof and one or more film forming agents to the external surface of the product, and then drying the coating composition to provide a dried coating or film on the external surface of the chocolate. The dried coating renders the external surface of the chocolate more resistant to abrasion or scuffing during processing, packaging, storage, and/or transport. The coating composition of the present invention cures or dries in 30 minutes or less. In certain embodiments, the film or coating cures in 15 minutes or less. In certain embodiments, the film or coating cures in 10 minutes or less.
    Type: Application
    Filed: September 20, 2013
    Publication date: May 1, 2014
    Applicant: Mantrose-Haeuser Company, Inc.
    Inventors: Bin Zhong, Margo McWeeney, Stephen A. Santos, Alan McGregor